James Beadle

Title(s)Recall Non-faculty Academic, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
vCardDownload vCard

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Enhanced broad spectrum in vitro antiviral efficacy of 3-F-4-MeO-Bn, 3-CN, and 4-CN derivatives of lipid remdesivir nucleoside monophosphate prodrugs. Antiviral Res. 2023 11; 219:105718. McMillan RE, Lo MK, Zhang XQ, Beadle JR, Valiaeva N, Garretson AF, Clark AE, Freshman JE, Murphy J, Montgomery JM, Spiropoulou CF, Schooley RT, Hostetler KY, Carlin AF. PMID: 37758067; PMCID: PMC10790242.
      View in: PubMed   Mentions:    Fields:    
    2. 1-O-Octadecyl-2-O-benzyl-sn-glyceryl-3-phospho-GS-441524 (V2043). Evaluation of Oral V2043 in a Mouse Model of SARS-CoV-2 Infection and Synthesis and Antiviral Evaluation of Additional Phospholipid Esters with Enhanced Anti-SARS-CoV-2 Activity. J Med Chem. 2023 04 27; 66(8):5802-5819. Carlin AF, Beadle JR, Clark AE, Gully KL, Moreira FR, Baric RS, Graham RL, Valiaeva N, Leibel SL, Bray W, McMillan RE, Freshman JE, Garretson AF, McVicar RN, Rana T, Zhang XQ, Murphy JA, Schooley RT, Hostetler KY. PMID: 37040439; PMCID: PMC10108740.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    3. Broad-Spectrum In Vitro Antiviral Activity of ODBG-P-RVn: An Orally-Available, Lipid-Modified Monophosphate Prodrug of Remdesivir Parent Nucleoside (GS-441524). Microbiol Spectr. 2021 12 22; 9(3):e0153721. Lo MK, Shrivastava-Ranjan P, Chatterjee P, Flint M, Beadle JR, Valiaeva N, Murphy J, Schooley RT, Hostetler KY, Montgomery JM, Spiropoulou CF. PMID: 34817209; PMCID: PMC8612139.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    4. Broad-spectrum in vitro antiviral activity of ODBG-P-RVn: an orally-available, lipid-modified monophosphate prodrug of remdesivir parent nucleoside (GS-441524). bioRxiv. 2021 Aug 10. Lo MK, Shrivastava-Ranjan P, Chatterjee P, Flint M, Beadle JR, Valiaeva N, Schooley RT, Hostetler KY, Montgomery JM, Spiropoulou C. PMID: 34401879; PMCID: PMC8366795.
      View in: PubMed   Mentions:
    5. Rethinking Remdesivir: Synthesis, Antiviral Activity, and Pharmacokinetics of Oral Lipid Prodrugs. Antimicrob Agents Chemother. 2021 09 17; 65(10):e0115521. Schooley RT, Carlin AF, Beadle JR, Valiaeva N, Zhang XQ, Clark AE, McMillan RE, Leibel SL, McVicar RN, Xie J, Garretson AF, Smith VI, Murphy J, Hostetler KY. PMID: 34310217; PMCID: PMC8448143.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    6. Rethinking Remdesivir: Synthesis, Antiviral Activity and Pharmacokinetics of Oral Lipid Prodrugs. bioRxiv. 2021 Jun 07. Schooley RT, Carlin AF, Beadle JR, Valiaeva N, Zhang XQ, Clark AE, McMillan RE, Leibel SL, McVicar RN, Xie J, Garretson AF, Smith VI, Murphy J, Hostetler KY. PMID: 32869033; PMCID: PMC7457622.
      View in: PubMed   Mentions: 1  
    7. Octadecyloxyethyl benzyl tenofovir: A novel tenofovir diester provides sustained intracellular levels of tenofovir diphosphate. Antiviral Res. 2019 11; 171:104614. Beadle JR, Aldern KA, Zhang XQ, Valiaeva N, Hostetler KY, Schooley RT. PMID: 31550449; PMCID: PMC6927535.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    8. Octadecyloxyethyl Adefovir Exhibits Potent in vitro and in vivo Cytotoxic Activity and Has Synergistic Effects with Ara-C in Acute Myeloid Leukemia. Chemotherapy. 2018; 63(4):225-237. Khoury H, He R, Schimmer A, Beadle JR, Hostetler KY, Minden MD. PMID: 30372692.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    9. Inhibition of adenovirus serotype 14 infection by octadecyloxyethyl esters of (S)-[(3-hydroxy-2-phosphonomethoxy)propyl]- nucleosides in vitro. Antiviral Res. 2018 10; 158:122-126. Kumaki Y, Woolcott JD, Roth JP, Mclean TZ, Smee DF, Barnard DL, Valiaeva N, Beadle JR, Hostetler KY. PMID: 30096340.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    10. Evaluation of ODE-Bn-PMEG, an acyclic nucleoside phosphonate prodrug, as an antiviral against productive HPV infection in 3D organotypic epithelial cultures. Antiviral Res. 2018 02; 150:164-173. Banerjee NS, Wang HK, Beadle JR, Hostetler KY, Chow LT. PMID: 29287913; PMCID: PMC5800947.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    11. A novel lipid prodrug strategy for sustained delivery of hexadecyloxypropyl 9-[2-(phosphonomethoxy)ethyl]guanine (HDP-PMEG) on unwanted ocular proliferation. Drug Deliv. 2017 Nov; 24(1):1703-1712. Chen M, Hou J, Tan G, Xie P, Freeman WR, Beadle JR, Hostetler KY, Cheng L. PMID: 29115885; PMCID: PMC8241053.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    12. Synthesis and Antiviral Evaluation of Octadecyloxyethyl Benzyl 9-[(2-Phosphonomethoxy)ethyl]guanine (ODE-Bn-PMEG), a Potent Inhibitor of Transient HPV DNA Amplification. J Med Chem. 2016 12 08; 59(23):10470-10478. Beadle JR, Valiaeva N, Yang G, Yu JH, Broker TR, Aldern KA, Harden EA, Keith KA, Prichard MN, Hartman T, Buckheit RW, Chow LT, Hostetler KY. PMID: 27933957.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    13. Micelle formulation of hexadecyloxypropyl-cidofovir (HDP-CDV) as an intravitreal long-lasting delivery system. Eur J Pharm Biopharm. 2015 Jan; 89:271-9. Ma F, Nan K, Lee S, Beadle JR, Hou H, Freeman WR, Hostetler KY, Cheng L. PMID: 25513956; PMCID: PMC4355386.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    14. A novel cytarabine crystalline lipid prodrug: hexadecyloxypropyl cytarabine 3',5'-cyclic monophosphate for proliferative vitreoretinopathy. Mol Vis. 2012; 18:1907-17. Kim JS, Beadle JR, Freeman WR, Hostetler KY, Hartmann K, Valiaeva N, Kozak I, Conner L, Trahan J, Aldern KA, Cheng L. PMID: 22876115; PMCID: PMC3413433.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    15. Intraocular safety and pharmacokinetics of hexadecyloxypropyl-cidofovir (HDP-CDV) as a long-lasting intravitreal antiviral drug. Invest Ophthalmol Vis Sci. 2011 Dec 09; 52(13):9391-6. Wang H, Chhablani J, Freeman WR, Beadle JR, Hostetler KY, Hartmann K, Conner L, Aldern KA, Pearson L, Cheng L. PMID: 22058340; PMCID: PMC3250264.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    16. Inhibition of HIV-1 by octadecyloxyethyl esters of (S)-[3-hydroxy-2-(phosphonomethoxy)propyl] nucleosides and evaluation of their mechanism of action. Antimicrob Agents Chemother. 2011 Nov; 55(11):5063-72. Magee WC, Valiaeva N, Beadle JR, Richman DD, Hostetler KY, Evans DH. PMID: 21896914; PMCID: PMC3195056.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    17. Synthesis and antiviral evaluation of 9-(S)-[3-alkoxy-2-(phosphonomethoxy)propyl]nucleoside alkoxyalkyl esters: inhibitors of hepatitis C virus and HIV-1 replication. Bioorg Med Chem. 2011 Aug 01; 19(15):4616-25. Valiaeva N, Wyles DL, Schooley RT, Hwu JB, Beadle JR, Prichard MN, Hostetler KY. PMID: 21719300; PMCID: PMC3139790.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    18. Synthesis, metabolic stability and antiviral evaluation of various alkoxyalkyl esters of cidofovir and 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine. Bioorg Med Chem. 2011 May 01; 19(9):2950-8. Ruiz J, Beadle JR, Buller RM, Schreiwer J, Prichard MN, Keith KA, Lewis KC, Hostetler KY. PMID: 21493074; PMCID: PMC3104040.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    19. Antiproliferative property of hexadecyloxypropyl 9-[2-(phosphonomethoxy) ethyl] guanine (HDP-PMEG) for unwanted ocular proliferation. Mol Vis. 2011 Mar 02; 17:627-37. Hou J, Li Y, Zhou Z, Valiaeva N, Beadle JR, Hostetler K, Freeman WR, Hu DN, Chen H, Cheng L. PMID: 21386925; PMCID: PMC3049735.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    20. Intraocular pharmacokinetics of a crystalline lipid prodrug, octadecyloxyethyl-cyclic-cidofovir, for cytomegalovirus retinitis. J Ocul Pharmacol Ther. 2011 Apr; 27(2):157-62. Cheng L, Beadle JR, Tammewar A, Hostetler KY, Hoh C, Freeman WR. PMID: 21351867; PMCID: PMC3078534.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    21. Solution structure of a DNA duplex containing the potent anti-poxvirus agent cidofovir. J Am Chem Soc. 2011 Feb 23; 133(7):2264-74. Julien O, Beadle JR, Magee WC, Chatterjee S, Hostetler KY, Evans DH, Sykes BD. PMID: 21280608; PMCID: PMC3051402.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    22. Oral hexadecyloxypropyl-cidofovir therapy in pregnant guinea pigs improves outcome in the congenital model of cytomegalovirus infection. Antimicrob Agents Chemother. 2011 Jan; 55(1):35-41. Bravo FJ, Bernstein DI, Beadle JR, Hostetler KY, Cardin RD. PMID: 21078944; PMCID: PMC3019685.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    23. Antiproliferative effects of octadecyloxyethyl 9-[2-(phosphonomethoxy)ethyl]guanine against Me-180 human cervical cancer cells in vitro and in vivo. Chemotherapy. 2010; 56(1):54-9. Valiaeva N, Trahan J, Aldern KA, Beadle JR, Hostetler KY. PMID: 20215748; PMCID: PMC2914419.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    24. Antiviral evaluation of octadecyloxyethyl esters of (S)-3-hydroxy-2-(phosphonomethoxy)propyl nucleosides against herpesviruses and orthopoxviruses. Antiviral Res. 2009 Dec; 84(3):254-9. Valiaeva N, Prichard MN, Buller RM, Beadle JR, Hartline CB, Keith KA, Schriewer J, Trahan J, Hostetler KY. PMID: 19800369; PMCID: PMC2787864.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    25. Antischistosomal activity of hexadecyloxypropyl cyclic 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine and other alkoxyalkyl esters of acyclic nucleoside phosphonates assessed by schistosome worm killing in vitro. Antimicrob Agents Chemother. 2009 Dec; 53(12):5284-7. Botros SS, William S, Beadle JR, Valiaeva N, Hostetler KY. PMID: 19704122; PMCID: PMC2786359.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    26. Intravitreal crystalline drug delivery for intraocular proliferation diseases. Invest Ophthalmol Vis Sci. 2010 Jan; 51(1):474-81. Cheng L, Hostetler K, Valiaeva N, Tammewar A, Freeman WR, Beadle J, Bartsch DU, Aldern K, Falkenstein I. PMID: 19696179; PMCID: PMC2869063.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    27. Alkoxyalkyl esters of 9-(s)-(3-hydroxy-2-phosphonomethoxypropyl) adenine are potent and selective inhibitors of hepatitis B virus (HBV) replication in vitro and in HBV transgenic mice in vivo. Antimicrob Agents Chemother. 2009 Jul; 53(7):2865-70. Morrey JD, Korba BE, Beadle JR, Wyles DL, Hostetler KY. PMID: 19398648; PMCID: PMC2704649.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    28. The octadecyloxyethyl ester of (S)-9-[3-hydroxy-2-(phosphonomethoxy) propyl]adenine is a potent and selective inhibitor of hepatitis C virus replication in genotype 1A, 1B, and 2A replicons. Antimicrob Agents Chemother. 2009 Jun; 53(6):2660-2. Wyles DL, Kaihara KA, Korba BE, Schooley RT, Beadle JR, Hostetler KY. PMID: 19289518; PMCID: PMC2687240.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    29. Inhibition of herpesvirus replication by hexadecyloxypropyl esters of purine- and pyrimidine-based phosphonomethoxyethyl nucleoside phosphonates. Antimicrob Agents Chemother. 2008 Dec; 52(12):4326-30. Prichard MN, Hartline CB, Harden EA, Daily SL, Beadle JR, Valiaeva N, Kern ER, Hostetler KY. PMID: 18852272; PMCID: PMC2592848.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    30. Effect of oral treatment with (S)-HPMPA, HDP-(S)-HPMPA or ODE-(S)-HPMPA on replication of murine cytomegalovirus (MCMV) or human cytomegalovirus (HCMV) in animal models. Antiviral Res. 2008 Aug; 79(2):133-5. Quenelle DC, Collins DJ, Pettway LR, Hartline CB, Beadle JR, Wan WB, Hostetler KY, Kern ER. PMID: 18336926; PMCID: PMC2650230.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    31. Anti-BK virus activity of nucleoside analogs. Antimicrob Agents Chemother. 2008 Apr; 52(4):1519-21. Randhawa P, Zemlicka J, Sauerbrei A, Meier C, Hostetler KY, Beadle JR, Farasati NA, Huang Y, Bradley M. PMID: 18285481; PMCID: PMC2292553.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    32. Intraocular properties of an alkoxyalkyl derivative of cyclic 9-(S)-(3-hydroxyl-2-phosphonomehoxypropyl) adenine, an intravitreally injectable anti-HCMV drug in rabbit and guinea pig. J Ocul Pharmacol Ther. 2007 Oct; 23(5):433-44. Tammewar AM, Cheng L, Hostetler KY, Falkenstein I, Beadle JR, Barron EC, Kozak I, Freeman WR. PMID: 17900229.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    33. Effect of oral treatment with hexadecyloxypropyl-[(S)-9-(3-hydroxy-2- phosphonylmethoxypropyl)adenine] [(S)-HPMPA] or octadecyloxyethyl-(S)-HPMPA on cowpox or vaccinia virus infections in mice. Antimicrob Agents Chemother. 2007 Nov; 51(11):3940-7. Quenelle DC, Collins DJ, Herrod BP, Keith KA, Trahan J, Beadle JR, Hostetler KY, Kern ER. PMID: 17846137; PMCID: PMC2151427.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    34. Evaluation of hexadecyloxypropyl-9-R-[2-(Phosphonomethoxy)propyl]- adenine, CMX157, as a potential treatment for human immunodeficiency virus type 1 and hepatitis B virus infections. Antimicrob Agents Chemother. 2007 Oct; 51(10):3505-9. Painter GR, Almond MR, Trost LC, Lampert BM, Neyts J, De Clercq E, Korba BE, Aldern KA, Beadle JR, Hostetler KY. PMID: 17646420; PMCID: PMC2043283.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    35. Synthesis of cidofovir and (S)-HPMPA ether lipid prodrugs. Curr Protoc Nucleic Acid Chem. 2007 Jun; Chapter 15:Unit 15.2. Beadle JR. PMID: 18428972.
      View in: PubMed   Mentions: 6     Fields:    
    36. In vitro evaluation of the anti-orf virus activity of alkoxyalkyl esters of CDV, cCDV and (S)-HPMPA. Antiviral Res. 2007 Jul; 75(1):52-7. Dal Pozzo F, Andrei G, Lebeau I, Beadle JR, Hostetler KY, De Clercq E, Snoeck R. PMID: 17184854.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    37. Synthesis of the 5-phosphono-pent-2-en-1-yl nucleosides: a new class of antiviral acyclic nucleoside phosphonates. Bioorg Med Chem. 2007 Feb 15; 15(4):1771-9. Choo H, Beadle JR, Chong Y, Trahan J, Hostetler KY. PMID: 17166725; PMCID: PMC1810563.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    38. Antiviral activities of novel 5-phosphono-pent-2-en-1-yl nucleosides and their alkoxyalkyl phosphonoesters. Antimicrob Agents Chemother. 2007 Feb; 51(2):611-5. Choo H, Beadle JR, Kern ER, Prichard MN, Keith KA, Hartline CB, Trahan J, Aldern KA, Korba BE, Hostetler KY. PMID: 17130297; PMCID: PMC1797766.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    39. Oral 1-O-octadecyl-2-O-benzyl-sn-glycero-3-cidofovir targets the lung and is effective against a lethal respiratory challenge with ectromelia virus in mice. Antiviral Res. 2007 Mar; 73(3):212-8. Hostetler KY, Beadle JR, Trahan J, Aldern KA, Owens G, Schriewer J, Melman L, Buller RM. PMID: 17123638; PMCID: PMC1859865.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    40. Synthesis and antiviral evaluation of alkoxyalkyl-phosphate conjugates of cidofovir and adefovir. Antiviral Res. 2007 Jul; 75(1):87-90. Ruiz JC, Beadle JR, Aldern KA, Keith KA, Hartline CB, Kern ER, Hostetler KY. PMID: 17367874; PMCID: PMC1899528.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    41. Alkoxyalkyl esters of (S)-9-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine are potent inhibitors of the replication of wild-type and drug-resistant human immunodeficiency virus type 1 in vitro. Antimicrob Agents Chemother. 2006 Aug; 50(8):2857-9. Hostetler KY, Aldern KA, Wan WB, Ciesla SL, Beadle JR. PMID: 16870786; PMCID: PMC1538655.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    42. Activities of alkoxyalkyl esters of cidofovir (CDV), cyclic CDV, and (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine against orthopoxviruses in cell monolayers and in organotypic cultures. Antimicrob Agents Chemother. 2006 Jul; 50(7):2525-9. Lebeau I, Andrei G, Dal Pozzo F, Beadle JR, Hostetler KY, De Clercq E, van den Oord J, Snoeck R. PMID: 16801436; PMCID: PMC1489770.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    43. Synthesis and antiviral evaluation of alkoxyalkyl esters of acyclic purine and pyrimidine nucleoside phosphonates against HIV-1 in vitro. Antiviral Res. 2006 Oct; 72(1):10-9. Valiaeva N, Beadle JR, Aldern KA, Trahan J, Hostetler KY. PMID: 16630664.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    44. Synthesis and antiviral evaluation of alkoxyalkyl derivatives of 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine against cytomegalovirus and orthopoxviruses. J Med Chem. 2006 Mar 23; 49(6):2010-5. Beadle JR, Wan WB, Ciesla SL, Keith KA, Hartline C, Kern ER, Hostetler KY. PMID: 16539388.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    45. Synthesis and antiviral evaluation of alkoxyalkyl esters of phosphonopropoxymethyl-guanine and phosphonopropoxymethyl-diaminopurine. Antivir Chem Chemother. 2006; 17(2):89-95. Ruiz JC, Aldern KA, Beadle JR, Hartline CB, Kern ER, Hostetler KY. PMID: 17042330.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    46. Enhanced antiproliferative effects of alkoxyalkyl esters of cidofovir in human cervical cancer cells in vitro. Mol Cancer Ther. 2006 Jan; 5(1):156-9. Hostetler KY, Rought S, Aldern KA, Trahan J, Beadle JR, Corbeil J. PMID: 16432174.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    47. Comparative activities of lipid esters of cidofovir and cyclic cidofovir against replication of herpesviruses in vitro. Antimicrob Agents Chemother. 2005 Sep; 49(9):3724-33. Williams-Aziz SL, Hartline CB, Harden EA, Daily SL, Prichard MN, Kushner NL, Beadle JR, Wan WB, Hostetler KY, Kern ER. PMID: 16127046; PMCID: PMC1195409.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    48. Intraocular properties of hexadecyloxypropyl-cyclic-cidofovir in Guinea pigs. J Ocul Pharmacol Ther. 2005 Jun; 21(3):205-9. Lu S, Cheng L, Hostetler KY, Koh HJ, Beadle JR, Davidson MC, Freeman WR. PMID: 15969637.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    49. Comparison of the antiviral activities of alkoxyalkyl and alkyl esters of cidofovir against human and murine cytomegalovirus replication in vitro. Antimicrob Agents Chemother. 2005 Feb; 49(2):656-62. Wan WB, Beadle JR, Hartline C, Kern ER, Ciesla SL, Valiaeva N, Hostetler KY. PMID: 15673748; PMCID: PMC547274.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    50. Ether lipid-ester prodrugs of acyclic nucleoside phosphonates: activity against adenovirus replication in vitro. J Infect Dis. 2005 Feb 01; 191(3):396-9. Hartline CB, Gustin KM, Wan WB, Ciesla SL, Beadle JR, Hostetler KY, Kern ER. PMID: 15633099.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    51. Characterization of a novel intraocular drug-delivery system using crystalline lipid antiviral prodrugs of ganciclovir and cyclic cidofovir. Invest Ophthalmol Vis Sci. 2004 Nov; 45(11):4138-44. Cheng L, Hostetler KY, Lee J, Koh HJ, Beadle JR, Bessho K, Toyoguchi M, Aldern K, Bovet JM, Freeman WR. PMID: 15505067; PMCID: PMC2666013.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    52. Oral treatment of murine cytomegalovirus infections with ether lipid esters of cidofovir. Antimicrob Agents Chemother. 2004 Sep; 48(9):3516-22. Kern ER, Collins DJ, Wan WB, Beadle JR, Hostetler KY, Quenelle DC. PMID: 15328119; PMCID: PMC514741.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    53. Oral activity of ether lipid ester prodrugs of cidofovir against experimental human cytomegalovirus infection. J Infect Dis. 2004 Aug 01; 190(3):499-503. Bidanset DJ, Beadle JR, Wan WB, Hostetler KY, Kern ER. PMID: 15243923.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    54. Inhibitory activity of alkoxyalkyl and alkyl esters of cidofovir and cyclic cidofovir against orthopoxvirus replication in vitro. Antimicrob Agents Chemother. 2004 May; 48(5):1869-71. Keith KA, Wan WB, Ciesla SL, Beadle JR, Hostetler KY, Kern ER. PMID: 15105146; PMCID: PMC400568.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    55. Effects of four antiviral substances on lethal vaccinia virus (IHD strain) respiratory infections in mice. Int J Antimicrob Agents. 2004 May; 23(5):430-7. Smee DF, Wong MH, Bailey KW, Beadle JR, Hostetler KY, Sidwell RW. PMID: 15120719.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    56. Oral treatment of cowpox and vaccinia virus infections in mice with ether lipid esters of cidofovir. Antimicrob Agents Chemother. 2004 Feb; 48(2):404-12. Quenelle DC, Collins DJ, Wan WB, Beadle JR, Hostetler KY, Kern ER. PMID: 14742188; PMCID: PMC321539.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    57. Efficacy of oral active ether lipid analogs of cidofovir in a lethal mousepox model. Virology. 2004 Jan 20; 318(2):474-81. Buller RM, Owens G, Schriewer J, Melman L, Beadle JR, Hostetler KY. PMID: 14972516.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    58. Esterification of cidofovir with alkoxyalkanols increases oral bioavailability and diminishes drug accumulation in kidney. Antiviral Res. 2003 Aug; 59(3):163-71. Ciesla SL, Trahan J, Wan WB, Beadle JR, Aldern KA, Painter GR, Hostetler KY. PMID: 12927306.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    59. Ganciclovir release rates in vitreous from different formulations of 1-O-hexadecylpropanediol-3-phospho-ganciclovir. J Ocul Pharmacol Ther. 2003 Apr; 19(2):161-9. Cheng L, Hostetler KY, Toyoguchi M, Beadle JR, Rodanant N, Gardner MF, Aldern KA, Bergeron-Lynn G, Freeman WR. PMID: 12804061.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    60. Alkoxyalkyl esters of cidofovir and cyclic cidofovir exhibit multiple-log enhancement of antiviral activity against cytomegalovirus and herpesvirus replication in vitro. Antimicrob Agents Chemother. 2002 Aug; 46(8):2381-6. Beadle JR, Hartline C, Aldern KA, Rodriguez N, Harden E, Kern ER, Hostetler KY. PMID: 12121908; PMCID: PMC127379.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    61. Enhanced inhibition of orthopoxvirus replication in vitro by alkoxyalkyl esters of cidofovir and cyclic cidofovir. Antimicrob Agents Chemother. 2002 Apr; 46(4):991-5. Kern ER, Hartline C, Harden E, Keith K, Rodriguez N, Beadle JR, Hostetler KY. PMID: 11897580; PMCID: PMC127114.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    62. Treatment or prevention of herpes simplex virus retinitis with intravitreally injectable crystalline 1-O-hexadecylpropanediol-3-phospho-ganciclovir. Invest Ophthalmol Vis Sci. 2002 Feb; 43(2):515-21. Cheng L, Hostetler KY, Chaidhawangul S, Gardner MF, Beadle JR, Toyoguchi M, Bergeron-Lynn G, Freeman WR. PMID: 11818399.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    James's Networks
    Concepts (234)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (12)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCSD Profiles is managed by the UC San Diego Altman Clinical and Translational Research Institute (ACTRI).
    This site is running Profiles RNS version UCSF-v3.1.0-3-g1ef1264b on PROFILES-PWEB04. We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use.

    Copyright © The Regents of the University of California