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Lawrence Leichman

Title(s)Clinical Professor, Medicine
SchoolHealth Sciences
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    THYMIDYLATE SYNTHASE QUANTITATION IN HUMAN COLON CANCER
    NIH/NCI U01CA060108Aug 18, 1993 - Jun 30, 1998
    Role: Co-Principal Investigator
    RESPONSE DETERMINANTS IN ESOPHAGEAL AND GASTRIC CANCERS
    NIH/NCI R01CA056119Feb 1, 1993 - Jan 31, 1996
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Zhao B, Leichman LP, Horgan S, Bouvet M, Kelly KJ. Evaluation of treatment and outcomes for Hispanic patients with gastric cancer at Commission on Cancer-accredited centers in the United States. J Surg Oncol. 2019 Feb 11. PMID: 30742314.
      View in: PubMed
    2. Kato S, Okamura R, Baumgartner JM, Patel H, Leichman L, Kelly K, Sicklick JK, Fanta PT, Lippman SM, Kurzrock R. Analysis of Circulating Tumor DNA and Clinical Correlates in Patients with Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma. Clin Cancer Res. 2018 Dec 15; 24(24):6248-6256. PMID: 30348637.
      View in: PubMed
    3. Lin D, Gold HT, Schreiber D, Leichman LP, Sherman SE, Becker DJ. Impact of socioeconomic status on survival for patients with anal cancer. Cancer. 2018 Apr 15; 124(8):1791-1797. PMID: 29527660.
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    4. Lin D, Goldberg JD, Hochman T, Levinson BA, Khan M, Newman E, Leichman LP, Gold HT. Delivery of adjuvant chemotherapy among stage III colon cancer patients at a public versus private hospital in New York City. Cancer Causes Control. 2018 Feb; 29(2):253-260. PMID: 29250702.
      View in: PubMed
    5. Guo S, Contratto M, Miller G, Leichman L, Wu J. Immunotherapy in pancreatic cancer: Unleash its potential through novel combinations. World J Clin Oncol. 2017 Jun 10; 8(3):230-240. PMID: 28638792.
      View in: PubMed
    6. Cohen SJ, O'Neil BH, Berlin J, Ames P, McKinley M, Horan J, Catalano PM, Davies A, Weekes CD, Leichman L. A phase 1b study of erlotinib in combination with gemcitabine and nab-paclitaxel in patients with previously untreated advanced pancreatic cancer: an Academic Oncology GI Cancer Consortium study. Cancer Chemother Pharmacol. 2016 Apr; 77(4):693-701. PMID: 26886016.
      View in: PubMed
    7. Leichman L, Groshen S, O'Neil BH, Messersmith W, Berlin J, Chan E, Leichman CG, Cohen SJ, Cohen D, Lenz HJ, Gold P, Boman B, Fielding A, Locker G, Cason RC, Hamilton SR, Hochster HS. Phase II Study of Olaparib (AZD-2281) After Standard Systemic Therapies for Disseminated Colorectal Cancer. Oncologist. 2016 Feb; 21(2):172-7. PMID: 26786262; PMCID: PMC4746089 [Available on 02/01/17].
    8. Grew D, Bitterman D, Leichman CG, Leichman L, Sanfilippo N, Moore HG, Du K. HIV Infection Is Associated With Poor Outcomes for Patients With Anal Cancer in the Highly Active Antiretroviral Therapy Era. Dis Colon Rectum. 2015 Dec; 58(12):1130-6. PMID: 26544809.
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    9. Bitterman DS, Grew D, Gu P, Cohen RF, Sanfilippo NJ, Leichman CG, Leichman LP, Moore HG, Gold HT, Du KL. Comparison of anal cancer outcomes in public and private hospital patients treated at a single radiation oncology center. J Gastrointest Oncol. 2015 Oct; 6(5):524-33. PMID: 26487947; PMCID: PMC4570920.
    10. Cohen DJ, Leichman L. Controversies in the treatment of local and locally advanced gastric and esophageal cancers. J Clin Oncol. 2015 Jun 01; 33(16):1754-9. PMID: 25918302.
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    11. Lin D, Leichman L. The current status of neoadjuvant therapy for esophageal cancer. Semin Thorac Cardiovasc Surg. 2014; 26(2):102-9. PMID: 25441001.
      View in: PubMed
    12. Leichman L. NO147: the Giving Tree. J Natl Cancer Inst. 2014 Jul; 106(7). PMID: 24925351.
      View in: PubMed
    13. Min C, Bangalore S, Jhawar S, Guo Y, Nicholson J, Formenti SC, Leichman LP, Du KL. Chemoradiation therapy versus chemotherapy alone for gastric cancer after R0 surgical resection: a meta-analysis of randomized trials. Oncology. 2014; 86(2):79-85. PMID: 24435019.
      View in: PubMed
    14. Leichman LP, Goldman BH, Bohanes PO, Lenz HJ, Thomas CR, Billingsley KG, Corless CL, Iqbal S, Gold PJ, Benedetti JK, Danenberg KD, Blanke CD. S0356: a phase II clinical and prospective molecular trial with oxaliplatin, fluorouracil, and external-beam radiation therapy before surgery for patients with esophageal adenocarcinoma. J Clin Oncol. 2011 Dec 01; 29(34):4555-60. PMID: 22025151.
      View in: PubMed
    15. Gross ME, Leichman L, Lowe ES, Swaisland A, Agus DB. Safety and pharmacokinetics of high-dose gefitinib in patients with solid tumors: results of a phase I study. Cancer Chemother Pharmacol. 2012 Jan; 69(1):273-80. PMID: 22002543.
      View in: PubMed
    16. Lorusso PM, Jimeno A, Dy G, Adjei A, Berlin J, Leichman L, Low JA, Colburn D, Chang I, Cheeti S, Jin JY, Graham RA. Pharmacokinetic dose-scheduling study of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with locally advanced or metastatic solid tumors. Clin Cancer Res. 2011 Sep 01; 17(17):5774-82. PMID: 21753154.
      View in: PubMed
    17. Leichman L, Thomas CR. Squamous cell cancer of the esophagus: the forgotten one. Gastrointest Cancer Res. 2011 Jan; 4(1):22-3. PMID: 21464867; PMCID: PMC3070285.
    18. Gold PJ, Goldman B, Iqbal S, Leichman LP, Zhang W, Lenz HJ, Blanke CD. Cetuximab as second-line therapy in patients with metastatic esophageal adenocarcinoma: a phase II Southwest Oncology Group Study (S0415). J Thorac Oncol. 2010 Sep; 5(9):1472-6. PMID: 20631636; PMCID: PMC2928397.
    19. Leichman L. On target? Off target? Why we really do not know. J Clin Oncol. 2010 Jun 20; 28(18):2937-8. PMID: 20458025.
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    20. Sparano JA, Lee JY, Kaplan LD, Levine AM, Ramos JC, Ambinder RF, Wachsman W, Aboulafia D, Noy A, Henry DH, Von Roenn J, Dezube BJ, Remick SC, Shah MH, Leichman L, Ratner L, Cesarman E, Chadburn A, Mitsuyasu R. Rituximab plus concurrent infusional EPOCH chemotherapy is highly effective in HIV-associated B-cell non-Hodgkin lymphoma. Blood. 2010 Apr 15; 115(15):3008-16. PMID: 20023215; PMCID: PMC2858478.
    21. Ilson DH, Wadleigh RG, Leichman LP, Kelsen DP. Paclitaxel given by a weekly 1-h infusion in advanced esophageal cancer. Ann Oncol. 2007 May; 18(5):898-902. PMID: 17351256.
      View in: PubMed
    22. Leichman L. Neoadjuvant chemotherapy for disseminated colorectal cancer: changing the paradigm. J Clin Oncol. 2006 Aug 20; 24(24):3817-8. PMID: 16921031.
      View in: PubMed
    23. Leichman L, Pendyala L, Leichman CG. Definitive and neoadjuvant therapies for esophageal and gastroesophageal junction tumors: a look back and toward the future. Semin Oncol. 2003 Aug; 30(4 Suppl 11):11-8. PMID: 14506599.
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    24. Garcia AA, Leichman L, Baranda J, Pandit L, Lenz HJ, Leichman CG. Phase II clinical trial of 5-fluorouracil, trimetrexate, and leucovorin (NFL) in patients with advanced pancreatic cancer. Int J Gastrointest Cancer. 2003; 34(2-3):79-86. PMID: 15361639.
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    25. Gergel TJ, Leichman L, Nava HR, Blumenson LE, Loewen GM, Gibbs JE, Khushalani NI, Leichman CG, Bodnar LM, Douglass HO, Smith JL, Kuettel MR, Proulx GM. Effect of concurrent radiation therapy and chemotherapy on pulmonary function in patients with esophageal cancer: dose-volume histogram analysis. Cancer J. 2002 Nov-Dec; 8(6):451-60. PMID: 12500854.
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    26. Khushalani NI, Leichman CG, Proulx G, Nava H, Bodnar L, Klippenstein D, Litwin A, Smith J, Nava E, Pendyala L, Smith P, Greco W, Berdzik J, Douglass H, Leichman L. Oxaliplatin in combination with protracted-infusion fluorouracil and radiation: report of a clinical trial for patients with esophageal cancer. J Clin Oncol. 2002 Jun 15; 20(12):2844-50. PMID: 12065561.
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    27. Lenz HJ, Hayashi K, Salonga D, Danenberg KD, Danenberg PV, Metzger R, Banerjee D, Bertino JR, Groshen S, Leichman LP, Leichman CG. p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: an analysis of response and survival. Clin Cancer Res. 1998 May; 4(5):1243-50. PMID: 9607583.
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    28. Lenz HJ, Danenberg KD, Leichman CG, Florentine B, Johnston PG, Groshen S, Zhou L, Xiong YP, Danenberg PV, Leichman LP. p53 and thymidylate synthase expression in untreated stage II colon cancer: associations with recurrence, survival, and site. Clin Cancer Res. 1998 May; 4(5):1227-34. PMID: 9607581.
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    29. Hayashi K, Metzger R, Salonga D, Danenberg K, Leichman LP, Fink U, Sendler A, Kelsen D, Schwartz GK, Groshen S, Lenz HJ, Danenberg PV. High frequency of simultaneous loss of p16 and p16beta gene expression in squamous cell carcinoma of the esophagus but not in adenocarcinoma of the esophagus or stomach. Oncogene. 1997 Sep 18; 15(12):1481-8. PMID: 9333024.
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    30. Muggia FM, Synold TW, Newman EM, Jeffers S, Leichman LP, Doroshow JH, Johnson K, Groshen S. Failure of pretreatment with intravenous folic acid to alter the cumulative hematologic toxicity of lometrexol. J Natl Cancer Inst. 1996 Oct 16; 88(20):1495-6. PMID: 8841028.
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    31. Seydel HG, Stablein DM, Leichman LP, Kinzie JJ, Thomas PR. Hyperfractionated radiation and chemotherapy for unresectable localized adenocarcinoma of the pancreas. The Gastrointestinal Tumor Study Group experience. Cancer. 1990 Apr 01; 65(7):1478-82. PMID: 2138054.
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    32. Bukowski RM, Leichman LP, Rivkin SE. Phase II trial of m-AMSA in gallbladder and cholangiocarcinoma: a Southwest Oncology Group Study. Eur J Cancer Clin Oncol. 1983 Jun; 19(6):721-3. PMID: 6307706.
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    33. Haas CD, Mansfield CM, Leichman LP, Considine B, Bukowski RM. Combined nonsimultaneous radiation therapy and chemotherapy with 5-FU, doxorubicin, and mitomycin for residual localized gastric adenocarcinoma: a Southwest Oncology Group pilot study. Cancer Treat Rep. 1983 May; 67(5):421-4. PMID: 6687837.
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    34. Knight WA, Loesch DM, Leichman LP, Fabian C, O'Bryan RM. Methyl-GAG in advanced colon cancer: a phase II trial of the Southwest Oncology Group. Cancer Treat Rep. 1982 Dec; 66(12):2099-100. PMID: 7139653.
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    35. Leichman LP, Baker LH, Stanhope CR, Samson MK, Fraile RJ, Vaitkevicius VK, Hilgers R. Mitomycin C and bleomycin in the treatment of far-advanced cervical cancer: a Southwest Oncology Group pilot study. Cancer Treat Rep. 1980 Oct-Nov; 64(10-11):1139-40. PMID: 6161699.
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