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    Lawrence Leichman

    TitleAssociate Physician Diplomate
    SchoolUniversity of California, San Diego
    DepartmentMedicine
    Address9500 Gilman Drive #0987
    CA La Jolla 92093
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      THYMIDYLATE SYNTHASE QUANTITATION IN HUMAN COLON CANCER
      NIH/NCI U01CA060108Aug 18, 1993 - Jun 30, 1998
      Role: Co-Principal Investigator
      RESPONSE DETERMINANTS IN ESOPHAGEAL AND GASTRIC CANCERS
      NIH/NCI R01CA056119Feb 1, 1993 - Jan 31, 1996
      Role: Principal Investigator

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      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Guo S, Contratto M, Miller G, Leichman L, Wu J. Immunotherapy in pancreatic cancer: Unleash its potential through novel combinations. World J Clin Oncol. 2017 Jun 10; 8(3):230-240. PMID: 28638792.
        View in: PubMed
      2. Cohen SJ, O'Neil BH, Berlin J, Ames P, McKinley M, Horan J, Catalano PM, Davies A, Weekes CD, Leichman L. A phase 1b study of erlotinib in combination with gemcitabine and nab-paclitaxel in patients with previously untreated advanced pancreatic cancer: an Academic Oncology GI Cancer Consortium study. Cancer Chemother Pharmacol. 2016 Apr; 77(4):693-701. PMID: 26886016.
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      3. Grew D, Bitterman D, Leichman CG, Leichman L, Sanfilippo N, Moore HG, Du K. HIV Infection Is Associated With Poor Outcomes for Patients With Anal Cancer in the Highly Active Antiretroviral Therapy Era. Dis Colon Rectum. 2015 Dec; 58(12):1130-6. PMID: 26544809.
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      4. O'Neil BH, Scott AJ, Ma WW, Cohen SJ, Leichman L, Aisner DL, Menter AR, Tejani MA, Cho JK, Granfortuna J, Coveler L, Olowokure OO, Baranda JC, Cusnir M, Phillip P, Boles J, Nazemzadeh R, Rarick M, Cohen DJ, Radford J, Fehrenbacher L, Bajaj R, Bathini V, Fanta P, Berlin J, McRee AJ, Maguire R, Wilhelm F, Maniar M, Jimeno A, Gomes CL, Messersmith WA. A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer. Ann Oncol. 2015 Dec; 26(12):2505. PMID: 26489442.
        View in: PubMed
      5. Bitterman DS, Grew D, Gu P, Cohen RF, Sanfilippo NJ, Leichman CG, Leichman L, Moore HG, Gold HT, Du KL. Comparison of anal cancer outcomes in public and private hospital patients treated at a single radiation oncology center. J Gastrointest Oncol. 2015 Oct; 6(5):524-33. PMID: 26487947; PMCID: PMC4570920.
      6. O'Neil BH, Scott AJ, Ma WW, Cohen SJ, Leichman L, Aisner DL, Menter AR, Tejani MA, Cho JK, Granfortuna J, Coveler L, Olowokure OO, Baranda JC, Cusnir M, Phillip P, Boles J, Nazemzadeh R, Rarick M, Cohen DJ, Radford J, Fehrenbacher L, Bajaj R, Bathini V, Fanta P, Berlin J, McRee AJ, Maguire R, Wilhelm F, Maniar M, Jimeno A, Gomes CL, Messersmith WA. A phase II/III randomized study to compare the efficacy and safety of rigosertib plus gemcitabine versus gemcitabine alone in patients with previously untreated metastatic pancreatic cancer. Ann Oncol. 2015 Sep; 26(9):1923-9. PMID: 26091808; PMCID: PMC4551155.
      7. Cohen DJ, Leichman L. Controversies in the treatment of local and locally advanced gastric and esophageal cancers. J Clin Oncol. 2015 Jun 01; 33(16):1754-9. PMID: 25918302.
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      8. Hochster HS, Uboha N, Messersmith W, Gold PJ, ONeil BH, Cohen D, Denlinger C, Cohen S, Leichman CG, Leichman L, Lenz HJ. Phase II study of selumetinib (AZD6244, ARRY-142886) plus irinotecan as second-line therapy in patients with K-RAS mutated colorectal cancer. Cancer Chemother Pharmacol. 2015 Jan; 75(1):17-23. PMID: 25322874.
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      9. Lin D, Leichman L. The current status of neoadjuvant therapy for esophageal cancer. Semin Thorac Cardiovasc Surg. 2014; 26(2):102-9. PMID: 25441001.
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      10. Leichman L. NO147: the Giving Tree. J Natl Cancer Inst. 2014 Jul; 106(7). PMID: 24925351.
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      11. Min C, Bangalore S, Jhawar S, Guo Y, Nicholson J, Formenti SC, Leichman L, Du KL. Chemoradiation therapy versus chemotherapy alone for gastric cancer after R0 surgical resection: a meta-analysis of randomized trials. Oncology. 2014; 86(2):79-85. PMID: 24435019.
        View in: PubMed
      12. Leichman L, Goldman BH, Bohanes PO, Lenz HJ, Thomas CR, Billingsley KG, Corless CL, Iqbal S, Gold PJ, Benedetti JK, Danenberg KD, Blanke CD. S0356: a phase II clinical and prospective molecular trial with oxaliplatin, fluorouracil, and external-beam radiation therapy before surgery for patients with esophageal adenocarcinoma. J Clin Oncol. 2011 Dec 01; 29(34):4555-60. PMID: 22025151; PMCID: PMC3236655.
      13. Gross ME, Leichman L, Lowe ES, Swaisland A, Agus DB. Safety and pharmacokinetics of high-dose gefitinib in patients with solid tumors: results of a phase I study. Cancer Chemother Pharmacol. 2012 Jan; 69(1):273-80. PMID: 22002543.
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      14. Lorusso PM, Jimeno A, Dy G, Adjei A, Berlin J, Leichman L, Low JA, Colburn D, Chang I, Cheeti S, Jin JY, Graham RA. Pharmacokinetic dose-scheduling study of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with locally advanced or metastatic solid tumors. Clin Cancer Res. 2011 Sep 01; 17(17):5774-82. PMID: 21753154.
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      15. Leichman L, Thomas CR. Squamous cell cancer of the esophagus: the forgotten one. Gastrointest Cancer Res. 2011 Jan; 4(1):22-3. PMID: 21464867; PMCID: PMC3070285.
      16. Gold PJ, Goldman B, Iqbal S, Leichman L, Zhang W, Lenz HJ, Blanke CD. Cetuximab as second-line therapy in patients with metastatic esophageal adenocarcinoma: a phase II Southwest Oncology Group Study (S0415). J Thorac Oncol. 2010 Sep; 5(9):1472-6. PMID: 20631636; PMCID: PMC2928397.
      17. Leichman L. On target? Off target? Why we really do not know. J Clin Oncol. 2010 Jun 20; 28(18):2937-8. PMID: 20458025.
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      18. Sparano JA, Lee JY, Kaplan LD, Levine AM, Ramos JC, Ambinder RF, Wachsman W, Aboulafia D, Noy A, Henry DH, Von Roenn J, Dezube BJ, Remick SC, Shah MH, Leichman L, Ratner L, Cesarman E, Chadburn A, Mitsuyasu R. Rituximab plus concurrent infusional EPOCH chemotherapy is highly effective in HIV-associated B-cell non-Hodgkin lymphoma. Blood. 2010 Apr 15; 115(15):3008-16. PMID: 20023215; PMCID: PMC2858478.
      19. Ilson DH, Wadleigh RG, Leichman L, Kelsen DP. Paclitaxel given by a weekly 1-h infusion in advanced esophageal cancer. Ann Oncol. 2007 May; 18(5):898-902. PMID: 17351256.
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      20. Leichman L, Lawrence D, Leichman CG, Nava H, Nava E, Proulx G, Clark K, Khushalani NI, Berdzik J, Greco W, Smith P, Creaven PJ, Kepner JL, Javle MM, Pendyala L. Expression of genes related to activity of oxaliplatin and 5-fluorouracil in endoscopic biopsies of primary esophageal cancer in patients receiving oxaliplatin, 5-flourouracil and radiation: characterization and exploratory analysis with survival. J Chemother. 2006 Oct; 18(5):514-24. PMID: 17127229.
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      21. Leichman L. Neoadjuvant chemotherapy for disseminated colorectal cancer: changing the paradigm. J Clin Oncol. 2006 Aug 20; 24(24):3817-8. PMID: 16921031.
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      22. Leichman L, Pendyala L, Leichman CG. Definitive and neoadjuvant therapies for esophageal and gastroesophageal junction tumors: a look back and toward the future. Semin Oncol. 2003 Aug; 30(4 Suppl 11):11-8. PMID: 14506599.
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      23. Garcia AA, Leichman L, Baranda J, Pandit L, Lenz HJ, Leichman CG. Phase II clinical trial of 5-fluorouracil, trimetrexate, and leucovorin (NFL) in patients with advanced pancreatic cancer. Int J Gastrointest Cancer. 2003; 34(2-3):79-86. PMID: 15361639.
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      24. Gergel TJ, Leichman L, Nava HR, Blumenson LE, Loewen GM, Gibbs JE, Khushalani NI, Leichman CG, Bodnar LM, Douglass HO, Smith JL, Kuettel MR, Proulx GM. Effect of concurrent radiation therapy and chemotherapy on pulmonary function in patients with esophageal cancer: dose-volume histogram analysis. Cancer J. 2002 Nov-Dec; 8(6):451-60. PMID: 12500854.
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      25. Khushalani NI, Leichman CG, Proulx G, Nava H, Bodnar L, Klippenstein D, Litwin A, Smith J, Nava E, Pendyala L, Smith P, Greco W, Berdzik J, Douglass H, Leichman L. Oxaliplatin in combination with protracted-infusion fluorouracil and radiation: report of a clinical trial for patients with esophageal cancer. J Clin Oncol. 2002 Jun 15; 20(12):2844-50. PMID: 12065561.
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      26. Gergel T, Proulx G, Leichman L, Nava H, Kuettel M. Diagnostic dilemmas in oncology: case 3. Pericardial effusion after esophageal radiation. J Clin Oncol. 2001 Dec 01; 19(23):4344-5. PMID: 11731519.
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      27. Garcia AA, Leichman CG, Lenz HJ, Baranda J, Lujan R, Casagrande Y, Leichman L. Phase II trial of outpatient schedule of paclitaxel in patients with previously untreated metastatic, measurable adenocarcinoma of the stomach. Jpn J Clin Oncol. 2001 Jun; 31(6):275-8. PMID: 11463806.
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      28. Leichman L, Leichman CG. Therapy of disseminated colorectal cancer: the emerging role of intratumoral molecular biology. Eur J Surg Suppl. 2001; (586):43-8. PMID: 11718526.
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      29. Salonga D, Danenberg KD, Johnson M, Metzger R, Groshen S, Tsao-Wei DD, Lenz HJ, Leichman CG, Leichman L, Diasio RB, Danenberg PV. Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase. Clin Cancer Res. 2000 Apr; 6(4):1322-7. PMID: 10778957.
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      30. Koda RT, Garcia AA, Chatterjee DJ, Li WY, Parimoo D, Jeffers S, Rogers M, Leichman CG, Leichman L, Wu EY, Shetty BV, Webber S, Clendinnin N, Muggia FM. Phase I study of AG 331, a novel thymidylate synthase inhibitor, in patients with refractory solid tumors. Cancer Chemother Pharmacol. 1999; 43(6):489-96. PMID: 10321509.
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      31. Metzger R, Danenberg K, Leichman CG, Salonga D, Schwartz EL, Wadler S, Lenz HJ, Groshen S, Leichman L, Danenberg PV. High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil. Clin Cancer Res. 1998 Oct; 4(10):2371-6. PMID: 9796967.
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      32. Lenz HJ, Danenberg KD, Leichman CG, Florentine B, Johnston PG, Groshen S, Zhou L, Xiong YP, Danenberg PV, Leichman L. p53 and thymidylate synthase expression in untreated stage II colon cancer: associations with recurrence, survival, and site. Clin Cancer Res. 1998 May; 4(5):1227-34. PMID: 9607581.
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      33. Lenz HJ, Hayashi K, Salonga D, Danenberg KD, Danenberg PV, Metzger R, Banerjee D, Bertino JR, Groshen S, Leichman L, Leichman CG. p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: an analysis of response and survival. Clin Cancer Res. 1998 May; 4(5):1243-50. PMID: 9607583.
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      34. Metzger R, Leichman CG, Danenberg KD, Danenberg PV, Lenz HJ, Hayashi K, Groshen S, Salonga D, Cohen H, Laine L, Crookes P, Silberman H, Baranda J, Konda B, Leichman L. ERCC1 mRNA levels complement thymidylate synthase mRNA levels in predicting response and survival for gastric cancer patients receiving combination cisplatin and fluorouracil chemotherapy. J Clin Oncol. 1998 Jan; 16(1):309-16. PMID: 9440758.
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      35. Leichman CG, Lenz HJ, Leichman L, Danenberg K, Baranda J, Groshen S, Boswell W, Metzger R, Tan M, Danenberg PV. Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin. J Clin Oncol. 1997 Oct; 15(10):3223-9. PMID: 9336359.
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      36. Hayashi K, Metzger R, Salonga D, Danenberg K, Leichman L, Fink U, Sendler A, Kelsen D, Schwartz GK, Groshen S, Lenz HJ, Danenberg PV. High frequency of simultaneous loss of p16 and p16beta gene expression in squamous cell carcinoma of the esophagus but not in adenocarcinoma of the esophagus or stomach. Oncogene. 1997 Sep 18; 15(12):1481-8. PMID: 9333024.
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      37. Crookes P, Leichman CG, Leichman L, Tan M, Laine L, Stain S, Baranda J, Casagrande Y, Groshen S, Silberman H. Systemic chemotherapy for gastric carcinoma followed by postoperative intraperitoneal therapy: a final report. Cancer. 1997 May 01; 79(9):1767-75. PMID: 9128994.
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      38. al-Sarraf M, Martz K, Herskovic A, Leichman L, Brindle JS, Vaitkevicius VK, Cooper J, Byhardt R, Davis L, Emami B. Progress report of combined chemoradiotherapy versus radiotherapy alone in patients with esophageal cancer: an intergroup study. J Clin Oncol. 1997 Jan; 15(1):277-84. PMID: 8996153.
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      39. Muggia FM, Synold TW, Newman EM, Jeffers S, Leichman L, Doroshow JH, Johnson K, Groshen S. Failure of pretreatment with intravenous folic acid to alter the cumulative hematologic toxicity of lometrexol. J Natl Cancer Inst. 1996 Oct 16; 88(20):1495-6. PMID: 8841028.
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      40. Muggia FM, Wu X, Spicer D, Groshen S, Jeffers S, Leichman CG, Leichman L, Chan KK. Phase I and pharmacokinetic study of oral UFT, a combination of the 5-fluorouracil prodrug tegafur and uracil. Clin Cancer Res. 1996 Sep; 2(9):1461-7. PMID: 9816321.
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      41. Leichman CG, Poplin E, Zalupski M, Garcia Y, Grant A, Angeles A, DeJong L, Leichman L. A pilot trial of continuous infusion 5-fluorouracil with levamisole for adjuvant therapy of colon cancer. J Infus Chemother. 1996; 6(2):84-6. PMID: 8809655.
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      42. Lenz HJ, Leichman CG, Danenberg KD, Danenberg PV, Groshen S, Cohen H, Laine L, Crookes P, Silberman H, Baranda J, Garcia Y, Li J, Leichman L. Thymidylate synthase mRNA level in adenocarcinoma of the stomach: a predictor for primary tumor response and overall survival. J Clin Oncol. 1996 Jan; 14(1):176-82. PMID: 8558194.
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      43. Lenz HJ, Danenberg KD, Schnieders B, Banerjee D, Bertino JR, Leichman L, Danenberg PV. Identification of mutations by RNA conformational polymorphism "bar code" analysis. Genomics. 1995 Nov 01; 30(1):120-2. PMID: 8595893.
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      44. Leichman L, Lenz HJ, Leichman CG, Groshen S, Danenberg K, Baranda J, Spears CP, Boswell W, Silberman H, Ortega A. Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: preliminary report from an ongoing trial. Eur J Cancer. 1995 Jul-Aug; 31A(7-8):1306-10. PMID: 7577041.
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      45. Johnston PG, Lenz HJ, Leichman CG, Danenberg KD, Allegra CJ, Danenberg PV, Leichman L. Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors. Cancer Res. 1995 Apr 01; 55(7):1407-12. PMID: 7882343.
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      46. Saltz LB, Leichman CG, Young CW, Muggia FM, Conti JA, Spiess T, Jeffers S, Leichman L. A fixed-ratio combination of uracil and Ftorafur (UFT) with low dose leucovorin. An active oral regimen for advanced colorectal cancer. Cancer. 1995 Feb 01; 75(3):782-5. PMID: 7828128.
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      47. Israel VK, Jiang C, Muggia FM, Tulpule A, Jeffers S, Leichman L, Morrow CP, Roman L, Leichman CG, Chan KK. Intraperitoneal 5-fluoro-2'-deoxyuridine (FUDR) and (S)-leucovorin for disease predominantly confined to the peritoneal cavity: a pharmacokinetic and toxicity study. Cancer Chemother Pharmacol. 1995; 37(1-2):32-8. PMID: 7497594.
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      48. Chen TC, Hinton DR, Leichman L, Atkinson RD, Apuzzo ML, Couldwell WT. Multifocal inflammatory leukoencephalopathy associated with levamisole and 5-fluorouracil: case report. Neurosurgery. 1994 Dec; 35(6):1138-42; discussion 1142-3. PMID: 7885561.
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      49. Muggia FM, Tulpule A, Retzios A, Chen F, Jeffers S, Leichman CG, Leichman L, Spears CP, Chan KK. Intraperitoneal 5-fluoro-2'-deoxyuridine with escalating doses of leucovorin: pharmacology and clinical tolerance. Invest New Drugs. 1994; 12(3):197-206. PMID: 7896538.
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      50. Leichman CG, Leichman L, Spears CP, Rosen PJ, Jeffers S, Groshen S. Prolonged continuous infusion of fluorouracil with weekly bolus leucovorin: a phase II study in patients with disseminated colorectal cancer. J Natl Cancer Inst. 1993 Jan 06; 85(1):41-4. PMID: 8416255.
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      51. Leichman L, Silberman H, Leichman CG, Spears CP, Ray M, Muggia FM, Kiyabu M, Radin R, Laine L, Stain S. Preoperative systemic chemotherapy followed by adjuvant postoperative intraperitoneal therapy for gastric cancer: a University of Southern California pilot program. J Clin Oncol. 1992 Dec; 10(12):1933-42. PMID: 1453207.
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      52. Kiyabu M, Leichman L, Chandrasoma P. Effects of preoperative chemotherapy on gastric adenocarcinomas. A morphologic study of 25 cases. Cancer. 1992 Nov 01; 70(9):2239-45. PMID: 1327491.
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      53. Herskovic A, Martz K, al-Sarraf M, Leichman L, Brindle J, Vaitkevicius V, Cooper J, Byhardt R, Davis L, Emami B. Combined chemotherapy and radiotherapy compared with radiotherapy alone in patients with cancer of the esophagus. N Engl J Med. 1992 Jun 11; 326(24):1593-8. PMID: 1584260.
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      54. Muggia FM, Brown TD, Goodman PJ, Macdonald JS, Hersh EM, Fleming TR, Leichman L. High incidence of coagualopathy in phase II studies of recombinant tumor necrosis factor in advanced pancreatic and gastric cancers. Anticancer Drugs. 1992 Jun; 3(3):211-7. PMID: 1525400.
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      55. Horikoshi T, Danenberg KD, Stadlbauer TH, Volkenandt M, Shea LC, Aigner K, Gustavsson B, Leichman L, Frösing R, Ray M. Quantitation of thymidylate synthase, dihydrofolate reductase, and DT-diaphorase gene expression in human tumors using the polymerase chain reaction. Cancer Res. 1992 Jan 01; 52(1):108-16. PMID: 1727369.
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      56. Leichman L, Berry BT. Cisplatin therapy for adenocarcinoma of the stomach. Semin Oncol. 1991 Feb; 18(1 Suppl 3):25-33. PMID: 2003225.
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      57. Leichman L, Berry BT. Experience with cisplatin in treatment regimens for esophageal cancer. Semin Oncol. 1991 Feb; 18(1 Suppl 3):64-72. PMID: 2003229.
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      58. Muggia FM, Chan KK, Russell C, Colombo N, Speyer JL, Sehgal K, Jeffers S, Sorich J, Leichman L, Beller U. Phase I and pharmacologic evaluation of intraperitoneal 5-fluoro-2'-deoxyuridine. Cancer Chemother Pharmacol. 1991; 28(4):241-50. PMID: 1831736.
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      59. Leichman L, Cummings BJ. Anal carcinoma. Curr Probl Cancer. 1990 May-Jun; 14(3):117-59. PMID: 2202554.
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      60. Seydel HG, Stablein DM, Leichman L, Kinzie JJ, Thomas PR. Hyperfractionated radiation and chemotherapy for unresectable localized adenocarcinoma of the pancreas. The Gastrointestinal Tumor Study Group experience. Cancer. 1990 Apr 01; 65(7):1478-82. PMID: 2138054.
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      61. Leichman CG, Leichman L, Spears CP, Rosen PJ, Muggia F, Jeffers S, Waugh W. Biological modification of protracted infusion of 5-fluorouracil with weekly leucovorin. A dose seeking clinical trial for patients with disseminated gastrointestinal cancers. Cancer Chemother Pharmacol. 1990; 26(1):57-61. PMID: 2182214.
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      62. Leichman L. Cancer of the esophagus: the Wayne State University experience. Invest New Drugs. 1989 Apr; 7(1):91-100. PMID: 2661486.
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      63. Leichman L. The role of chemotherapy in the treatment of squamous cell tumors of the esophagus. Cancer Treat Res. 1989; 42:127-49. PMID: 2577101.
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      64. Herskovic A, Leichman L, Lattin P, Han I, Ahmad K, Leichman G, Rosenberg J, Steiger Z, Bendal C, White B. Chemo/radiation with and without surgery in the thoracic esophagus: the Wayne State experience. Int J Radiat Oncol Biol Phys. 1988 Sep; 15(3):655-62. PMID: 3138217.
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      65. Shepard KV, Larson R, Le Beau MM, Leichman L, Levin B. Acute leukemia occurring after radiotherapy and chemotherapy with a nitrosourea, PCNU. Invest New Drugs. 1988 Jun; 6(2):121-4. PMID: 3170132.
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      66. Seydel HG, Leichman L, Byhardt R, Cooper J, Herskovic A, Libnock J, Pazdur R, Speyer J, Tschan J. Preoperative radiation and chemotherapy for localized squamous cell carcinoma of the esophagus: a RTOG Study. Int J Radiat Oncol Biol Phys. 1988 Jan; 14(1):33-5. PMID: 3335460.
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      67. Steiger Z, Wilson RF, Leichman L, Busuito MJ, Rosenberg JC. Primary adenocarcinoma of the esophagus. J Surg Oncol. 1987 Sep; 36(1):68-70. PMID: 3626564.
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      68. Poplin E, Fleming T, Leichman L, Seydel HG, Steiger Z, Taylor S, Vance R, Stuckey WJ, Rivkin SE. Combined therapies for squamous-cell carcinoma of the esophagus, a Southwest Oncology Group Study (SWOG-8037). J Clin Oncol. 1987 Apr; 5(4):622-8. PMID: 3559653.
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      69. Leichman L, Herskovic A, Leichman CG, Lattin PB, Steiger Z, Tapazoglou E, Rosenberg JC, Arbulu A, Asfaw I, Kinzie J. Nonoperative therapy for squamous-cell cancer of the esophagus. J Clin Oncol. 1987 Mar; 5(3):365-70. PMID: 2434626.
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      70. Karanes C, Ratanatharathorn V, Schilcher RB, Young JD, Emmer D, Hoschner JA, Leichman L, Baker LH. High-dose mitomycin-C with autologous bone marrow transplantation in patients with refractory malignancies. Influence of dose schedule on pharmacokinetics and nonhematopoietic toxicities. Am J Clin Oncol. 1986 Oct; 9(5):444-8. PMID: 3096129.
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      71. Sternberg C, Kelsen D, Dukeman M, Leichman L, Heelan R. Carboplatin: a new platinum analog in the treatment of epidermoid carcinoma of the esophagus. Cancer Treat Rep. 1985 Nov; 69(11):1305-7. PMID: 3912041.
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      72. Leichman L, Nigro N, Vaitkevicius VK, Considine B, Buroker T, Bradley G, Seydel HG, Olchowski S, Cummings G, Leichman C. Cancer of the anal canal. Model for preoperative adjuvant combined modality therapy. Am J Med. 1985 Feb; 78(2):211-5. PMID: 3918441.
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      73. Panettiere FJ, Leichman L, Tilchen EJ, Chen TT. Chemotherapy for advanced epidermoid carcinoma of the esophagus with single-agent cisplatin: final report on a Southwest Oncology Group study. Cancer Treat Rep. 1984 Jul-Aug; 68(7-8):1023-4. PMID: 6540144.
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      74. Leichman L, Steiger Z, Seydel HG, Vaitkevicius VK. Combined preoperative chemotherapy and radiation therapy for cancer of the esophagus: the Wayne State University, Southwest Oncology group and Radiation Therapy Oncology Group experience. Semin Oncol. 1984 Jun; 11(2):178-85. PMID: 6427931.
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      75. Leichman L, Steiger Z, Seydel HG, Dindogru A, Kinzie J, Toben S, MacKenzie G, Shell J. Preoperative chemotherapy and radiation therapy for patients with cancer of the esophagus: a potentially curative approach. J Clin Oncol. 1984 Feb; 2(2):75-9. PMID: 6538224.
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      76. Leichman L, McDonald B, Dindogru A, Samson M, Vaitkevicius VK. Cisplatin. An active drug in the treatment of disseminated gastric cancer. Cancer. 1984 Jan 01; 53(1):18-22. PMID: 6317158.
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      77. Haynes JW, Miller PR, Steiger Z, Leichman L, Kling GA. Celestin tube use: radiographic manifestations of associated complications. Radiology. 1984 Jan; 150(1):41-4. PMID: 6196808.
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      78. Steiger Z, Wilson RF, Leichman L, Franklin R, Dindogru A, Kinzie J. Management of malignant bronchoesophageal fistulas. Surg Gynecol Obstet. 1983 Sep; 157(3):201-4. PMID: 6612568.
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      79. Schilcher RB, Young JD, Leichman L, Haas CD, Baker LH. Phase I evaluation and pharmacokinetics of aziridinylbenzoquinone using a weekly intravenous schedule. Cancer Res. 1983 Aug; 43(8):3907-11. PMID: 6683127.
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      80. Bukowski RM, Leichman L, Rivkin SE. Phase II trial of m-AMSA in gallbladder and cholangiocarcinoma: a Southwest Oncology Group Study. Eur J Cancer Clin Oncol. 1983 Jun; 19(6):721-3. PMID: 6307706.
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      81. Nigro ND, Seydel HG, Considine B, Vaitkevicius VK, Leichman L, Kinzie JJ. Combined preoperative radiation and chemotherapy for squamous cell carcinoma of the anal canal. Cancer. 1983 May 15; 51(10):1826-9. PMID: 6831348.
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      82. Haas CD, Mansfield CM, Leichman L, Considine B, Bukowski RM. Combined nonsimultaneous radiation therapy and chemotherapy with 5-FU, doxorubicin, and mitomycin for residual localized gastric adenocarcinoma: a Southwest Oncology Group pilot study. Cancer Treat Rep. 1983 May; 67(5):421-4. PMID: 6687837.
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      83. Knight WA, Loesch DM, Leichman L, Fabian C, O'Bryan RM. Methyl-GAG in advanced colon cancer: a phase II trial of the Southwest Oncology Group. Cancer Treat Rep. 1982 Dec; 66(12):2099-100. PMID: 7139653.
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