Umber Dube

Title(s)Resident Physician, Dermatology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer's disease brains. Alzheimers Dement. 2023 05; 19(5):1785-1799. Novotny BC, Fernandez MV, Wang C, Budde JP, Bergmann K, Eteleeb AM, Bradley J, Webster C, Ebl C, Norton J, Gentsch J, Dube U, Wang F, Morris JC, Bateman RJ, Perrin RJ, McDade E, Xiong C, Chhatwal J, Dominantly Inherited Alzheimer Network (DIAN) Study Group, Alzheimer's Disease Neuroimaging Initiative, Alzheimer's Disease Metabolomics Consortium (ADMC), Goate A, Farlow M, Schofield P, Chui H, Karch CM, Cruchaga C, Benitez BA, Harari O. PMID: 36251323; PMCID: PMC10106526.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    2. Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders. Nat Neurosci. 2021 09; 24(9):1302-1312. Yang C, Farias FHG, Ibanez L, Suhy A, Sadler B, Fernandez MV, Wang F, Bradley JL, Eiffert B, Bahena JA, Budde JP, Li Z, Dube U, Sung YJ, Mihindukulasuriya KA, Morris JC, Fagan AM, Perrin RJ, Benitez BA, Rhinn H, Harari O, Cruchaga C. PMID: 34239129; PMCID: PMC8521603.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    3. Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease. Acta Neuropathol Commun. 2020 11 19; 8(1):196. Ibanez L, Bahena JA, Yang C, Dube U, Farias FHG, Budde JP, Bergmann K, Brenner-Webster C, Morris JC, Perrin RJ, Cairns NJ, O'Donnell J, Álvarez I, Diez-Fairen M, Aguilar M, Miller R, Davis AA, Pastor P, Kotzbauer P, Campbell MC, Perlmutter JS, Rhinn H, Harari O, Cruchaga C, Benitez BA. PMID: 33213513; PMCID: PMC7678051.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    4. Correction to: Overlapping genetic architecture between Parkinson disease and melanoma. Acta Neuropathol. 2020 05; 139(5):963. Dube U, Ibanez L, Budde JP, Benitez BA, Davis AA, Harari O, Iles MM, Law MH, Brown KM, 23andMe Research Team, Melanoma-Meta-analysis Consortium, Cruchaga C. PMID: 32172342.
      View in: PubMed   Mentions:    Fields:    
    5. APOE genotype regulates pathology and disease progression in synucleinopathy. Sci Transl Med. 2020 02 05; 12(529). Davis AA, Inman CE, Wargel ZM, Dube U, Freeberg BM, Galluppi A, Haines JN, Dhavale DD, Miller R, Choudhury FA, Sullivan PM, Cruchaga C, Perlmutter JS, Ulrich JD, Benitez BA, Kotzbauer PT, Holtzman DM. PMID: 32024799; PMCID: PMC7289511.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimals
    6. Examination of the Effect of Rare Variants in TREM2, ABI3, and PLCG2 in LOAD Through Multiple Phenotypes. J Alzheimers Dis. 2020; 77(4):1469-1482. Olive C, Ibanez L, Farias FHG, Wang F, Budde JP, Norton JB, Gentsch J, Morris JC, Li Z, Dube U, Del-Aguila J, Bergmann K, Bradley J, Benitez BA, Harari O, Fagan A, Ances B, Cruchaga C, Fernandez MV. PMID: 32894242; PMCID: PMC7927150.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    7. Well Water and Parkinson's Disease in Medicare Beneficiaries: A Nationwide Case-Control Study. J Parkinsons Dis. 2020; 10(2):693-705. Silver MR, Racette BA, Dube U, Faust IM, Searles Nielsen S. PMID: 32083591; PMCID: PMC7342021.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    8. Overlapping genetic architecture between Parkinson disease and melanoma. Acta Neuropathol. 2020 02; 139(2):347-364. Dube U, Ibanez L, Budde JP, Benitez BA, Davis AA, Harari O, Iles MM, Law MH, Brown KM, 23andMe Research Team, Melanoma-Meta-analysis Consortium, Cruchaga C. PMID: 31845298; PMCID: PMC7379325.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    9. An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations. Nat Neurosci. 2019 11; 22(11):1903-1912. Dube U, Del-Aguila JL, Li Z, Budde JP, Jiang S, Hsu S, Ibanez L, Fernandez MV, Farias F, Norton J, Gentsch J, Wang F, Dominantly Inherited Alzheimer Network (DIAN), Salloway S, Masters CL, Lee JH, Graff-Radford NR, Chhatwal JP, Bateman RJ, Morris JC, Karch CM, Harari O, Cruchaga C. PMID: 31591557; PMCID: PMC6858549.
      View in: PubMed   Mentions: 148     Fields:    Translation:Humans
    10. The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion. Acta Neuropathol. 2020 01; 139(1):45-61. Li Z, Farias FHG, Dube U, Del-Aguila JL, Mihindukulasuriya KA, Fernandez MV, Ibanez L, Budde JP, Wang F, Lake AM, Deming Y, Perez J, Yang C, Bahena JA, Qin W, Bradley JL, Davenport R, Bergmann K, Morris JC, Perrin RJ, Benitez BA, Dougherty JD, Harari O, Cruchaga C. PMID: 31456032; PMCID: PMC6942643.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    11. The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk. Sci Transl Med. 2019 08 14; 11(505). Deming Y, Filipello F, Cignarella F, Cantoni C, Hsu S, Mikesell R, Li Z, Del-Aguila JL, Dube U, Farias FG, Bradley J, Budde J, Ibanez L, Fernandez MV, Blennow K, Zetterberg H, Heslegrave A, Johansson PM, Svensson J, Nellgård B, Lleo A, Alcolea D, Clarimon J, Rami L, Molinuevo JL, Suárez-Calvet M, Morenas-Rodríguez E, Kleinberger G, Ewers M, Harari O, Haass C, Brett TJ, Benitez BA, Karch CM, Piccio L, Cruchaga C. PMID: 31413141; PMCID: PMC6697053.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCells
    12. A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain. Alzheimers Res Ther. 2019 08 09; 11(1):71. Del-Aguila JL, Li Z, Dube U, Mihindukulasuriya KA, Budde JP, Fernandez MV, Ibanez L, Bradley J, Wang F, Bergmann K, Davenport R, Morris JC, Holtzman DM, Perrin RJ, Benitez BA, Dougherty J, Cruchaga C, Harari O. PMID: 31399126; PMCID: PMC6689177.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansCells
    13. Overlap in the Genetic Architecture of Stroke Risk, Early Neurological Changes, and Cardiovascular Risk Factors. Stroke. 2019 06; 50(6):1339-1345. Ibanez L, Heitsch L, Dube U, Farias FHG, Budde J, Bergmann K, Davenport R, Bradley J, Carrera C, Kinnunen J, Sallinen H, Strbian D, Slowik A, Fernandez-Cadenas I, Montaner J, Lee JM, Cruchaga C. PMID: 31084338; PMCID: PMC6538457.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    14. TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers. Mol Neurodegener. 2019 05 08; 14(1):18. Del-Aguila JL, Benitez BA, Li Z, Dube U, Mihindukulasuriya KA, Budde JP, Farias FHG, Fernández MV, Ibanez L, Jiang S, Perrin RJ, Cairns NJ, Morris JC, Harari O, Cruchaga C. PMID: 31068200; PMCID: PMC6505298.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    15. Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP. Transl Psychiatry. 2018 12 13; 8(1):265. Jiang S, Wen N, Li Z, Dube U, Del Aguila J, Budde J, Martinez R, Hsu S, Fernandez MV, Cairns NJ, Dominantly Inherited Alzheimer Network (DIAN), International FTD-Genomics Consortium (IFGC), Harari O, Cruchaga C, Karch CM. PMID: 30546007; PMCID: PMC6293323.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    16. Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure. Genome Med. 2018 06 08; 10(1):43. Li Z, Del-Aguila JL, Dube U, Budde J, Martinez R, Black K, Xiao Q, Cairns NJ, Dominantly Inherited Alzheimer Network (DIAN), Dougherty JD, Lee JM, Morris JC, Bateman RJ, Karch CM, Cruchaga C, Harari O. PMID: 29880032; PMCID: PMC5992755.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    17. Use of medical care biases associations between Parkinson disease and other medical conditions. Neurology. 2018 06 12; 90(24):e2155-e2165. Gross A, Racette BA, Camacho-Soto A, Dube U, Searles Nielsen S. PMID: 29743207; PMCID: PMC5996836.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    18. Pleiotropic Effects of Variants in Dementia Genes in Parkinson Disease. Front Neurosci. 2018; 12:230. Ibanez L, Dube U, Davis AA, Fernandez MV, Budde J, Cooper B, Diez-Fairen M, Ortega-Cubero S, Pastor P, Perlmutter JS, Cruchaga C, Benitez BA. PMID: 29692703; PMCID: PMC5902712.
      View in: PubMed   Mentions: 11  
    19. Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels. BMC Neurol. 2017 Nov 15; 17(1):198. Ibanez L, Dube U, Saef B, Budde J, Black K, Medvedeva A, Del-Aguila JL, Davis AA, Perlmutter JS, Harari O, Benitez BA, Cruchaga C. PMID: 29141588; PMCID: PMC5688622.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    20. Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease. PLoS Genet. 2017 Nov; 13(11):e1007045. Fernández MV, Kim JH, Budde JP, Black K, Medvedeva A, Saef B, Deming Y, Del-Aguila J, Ibañez L, Dube U, Harari O, Norton J, Chasse R, Morris JC, Goate A, NIA-LOAD family study group, NCRAD, Cruchaga C. PMID: 29091718; PMCID: PMC5683650.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    21. TMEM230 in Parkinson's disease. Neurobiol Aging. 2017 08; 56:212.e1-212.e3. Ibanez L, Dube U, Budde J, Black K, Medvedeva A, Davis AA, Perlmutter JS, Benitez BA, Cruchaga C. PMID: 28457580; PMCID: PMC5526081.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    22. Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex. Cell. 2012 May 11; 149(4):899-911. Kwan KY, Lam MM, Johnson MB, Dube U, Shim S, Rašin MR, Sousa AM, Fertuzinhos S, Chen JG, Arellano JI, Chan DW, Pletikos M, Vasung L, Rowitch DH, Huang EJ, Schwartz ML, Willemsen R, Oostra BA, Rakic P, Heffer M, Kostovic I, Judaš M, Sestan N. PMID: 22579290; PMCID: PMC3351852.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
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