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    Kevin Brown

    TitleProfessor
    SchoolUniversity of California, San Diego
    DepartmentGeosciences Research Division
    Address9500 Gilman Drive #0225
    CA La Jolla 92093
    Phone858-822-4077
    vCardDownload vCard

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Machiela MJ, Hofmann JN, Carreras-Torres R, Brown K, Johansson M, Wang Z, Foll M, Li P, Rothman N, Savage SA, Gaborieau V, McKay JD, Ye Y, Henrion M, Bruinsma F, Jordan S, Severi G, Hveem K, Vatten LJ, Fletcher T, Koppova K, Larsson SC, Wolk A, Banks RE, Selby PJ, Easton DF, Pharoah P, Andreotti G, Freeman LEB, Koutros S, Albanes D, Mannisto S, Weinstein S, Clark PE, Edwards TE, Lipworth L, Gapstur SM, Stevens VL, Carol H, Freedman ML, Pomerantz MM, Cho E, Kraft P, Preston MA, Wilson KM, Gaziano JM, Sesso HS, Black A, Freedman ND, Huang WY, Anema JG, Kahnoski RJ, Lane BR, Noyes SL, Petillo D, Colli LM, Sampson JN, Besse C, Blanche H, Boland A, Burdette L, Prokhortchouk E, Skryabin KG, Yeager M, Mijuskovic M, Ognjanovic M, Foretova L, Holcatova I, Janout V, Mates D, Mukeriya A, Rascu S, Zaridze D, Bencko V, Cybulski C, Fabianova E, Jinga V, Lissowska J, Lubinski J, Navratilova M, Rudnai P, Szeszenia-Dabrowska N, Benhamou S, Cancel-Tassin G, Cussenot O, Bueno-de-Mesquita HB, Canzian F, Duell EJ, Ljungberg B, Sitaram RT, Peters U, White E, Anderson GL, Johnson L, Luo J, Buring J, Lee IM, Chow WH, Moore LE, Wood C, Eisen T, Larkin J, Choueiri TK, Lathrop GM, Teh BT, Deleuze JF, Wu X, Houlston RS, Brennan P, Chanock SJ, Scelo G, Purdue MP. Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma. Eur Urol. 2017 Aug 07. PMID: 28797570.
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      2. Choi J, Xu M, Makowski MM, Zhang T, Law MH, Kovacs MA, Granzhan A, Kim WJ, Parikh H, Gartside M, Trent JM, Teulade-Fichou MP, Iles MM, Newton-Bishop JA, Bishop DT, MacGregor S, Hayward NK, Vermeulen M, Brown K. A common intronic variant of PARP1 confers melanoma risk and mediates melanocyte growth via regulation of MITF. Nat Genet. 2017 Sep; 49(9):1326-1335. PMID: 28759004.
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      3. Zhang M, Lykke-Andersen S, Zhu B, Xiao W, Hoskins JW, Zhang X, Rost LM, Collins I, Bunt MV, Jia J, Parikh H, Zhang T, Song L, Jermusyk A, Chung CC, Zhu B, Zhou W, Matters GL, Kurtz RC, Yeager M, Jensen TH, Brown K, Ongen H, Bamlet WR, Murray BA, McCarthy MI, Chanock SJ, Chatterjee N, Wolpin BM, Smith JP, Olson SH, Petersen GM, Shi J, Amundadottir L. Characterising cis-regulatory variation in the transcriptome of histologically normal and tumour-derived pancreatic tissues. Gut. 2017 Jun 20. PMID: 28634199.
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      4. Scelo G, Purdue MP, Brown K, Johansson M, Wang Z, Eckel-Passow JE, Ye Y, Hofmann JN, Choi J, Foll M, Gaborieau V, Machiela MJ, Colli LM, Li P, Sampson JN, Abedi-Ardekani B, Besse C, Blanche H, Boland A, Burdette L, Chabrier A, Durand G, Le Calvez-Kelm F, Prokhortchouk E, Robinot N, Skryabin KG, Wozniak MB, Yeager M, Basta-Jovanovic G, Dzamic Z, Foretova L, Holcatova I, Janout V, Mates D, Mukeriya A, Rascu S, Zaridze D, Bencko V, Cybulski C, Fabianova E, Jinga V, Lissowska J, Lubinski J, Navratilova M, Rudnai P, Szeszenia-Dabrowska N, Benhamou S, Cancel-Tassin G, Cussenot O, Baglietto L, Boeing H, Khaw KT, Weiderpass E, Ljungberg B, Sitaram RT, Bruinsma F, Jordan SJ, Severi G, Winship I, Hveem K, Vatten LJ, Fletcher T, Koppova K, Larsson SC, Wolk A, Banks RE, Selby PJ, Easton DF, Pharoah P, Andreotti G, Freeman LEB, Koutros S, Albanes D, Männistö S, Weinstein S, Clark PE, Edwards TL, Lipworth L, Gapstur SM, Stevens VL, Carol H, Freedman ML, Pomerantz MM, Cho E, Kraft P, Preston MA, Wilson KM, Michael Gaziano J, Sesso HD, Black A, Freedman ND, Huang WY, Anema JG, Kahnoski RJ, Lane BR, Noyes SL, Petillo D, Teh BT, Peters U, White E, Anderson GL, Johnson L, Luo J, Buring J, Lee IM, Chow WH, Moore LE, Wood C, Eisen T, Henrion M, Larkin J, Barman P, Leibovich BC, Choueiri TK, Mark Lathrop G, Rothman N, Deleuze JF, McKay JD, Parker AS, Wu X, Houlston RS, Brennan P, Chanock SJ. Genome-wide association study identifies multiple risk loci for renal cell carcinoma. Nat Commun. 2017 Jun 09; 8:15724. PMID: 28598434.
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      5. Long S, Brown K, Drewry LL, Anthony B, Phan IQH, Sibley LD. Calmodulin-like proteins localized to the conoid regulate motility and cell invasion by Toxoplasma gondii. PLoS Pathog. 2017 May; 13(5):e1006379. PMID: 28475612.
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      6. Fang J, Jia J, Makowski M, Xu M, Wang Z, Zhang T, Hoskins JW, Choi J, Han Y, Zhang M, Thomas J, Kovacs M, Collins I, Dzyadyk M, Thompson A, O'Neill M, Das S, Lan Q, Koster R. Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148. Nat Commun. 2017 May 02; 8:15034. PMID: 28447668.
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      7. Zhang T, Xu M, Makowski MM, Lee C, Kovacs M, Fang J, Willems E, Trent JM, Hayward NK, Vermeulen M, Brown K. SDHD promoter mutations ablate GABP transcription factor binding in melanoma. Cancer Res. 2017 Jan 20. PMID: 28108517.
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      8. Chung JY, Choi J, Sears JD, Ylaya K, Perry C, Choi CH, Hong SM, Cho H, Brown K, Hewitt SM. A melanin-bleaching methodology for molecular and histopathological analysis of formalin-fixed paraffin-embedded tissue. Lab Invest. 2016 Oct; 96(10):1116-27. PMID: 27548802.
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      9. Claps G, Cheli Y, Zhang T, Scortegagna M, Lau E, Kim H, Qi J, Li JL, James B, Dzung A, Levesque MP, Dummer R, Hayward NK, Bosenberg M, Brown K, Ronai ZA. A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis. Cell Rep. 2016 May 31; 15(9):1884-92. PMID: 27210757.
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      10. Zhang T, Dutton-Regester K, Brown K, Hayward NK. The genomic landscape of cutaneous melanoma. Pigment Cell Melanoma Res. 2016 May; 29(3):266-83. PMID: 26833684.
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      11. Brown K, Lourido S, Sibley LD. Serum Albumin Stimulates Protein Kinase G-dependent Microneme Secretion in Toxoplasma gondii. J Biol Chem. 2016 Apr 29; 291(18):9554-65. PMID: 26933037.
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      12. Makowski MM, Willems E, Fang J, Choi J, Zhang T, Jansen PW, Brown K, Vermeulen M. An interaction proteomics survey of transcription factor binding at recurrent TERT promoter mutations. Proteomics. 2016 Feb; 16(3):417-26. PMID: 26553150.
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      13. Harland M, Petljak M, Robles-Espinoza CD, Ding Z, Gruis NA, van Doorn R, Pooley KA, Dunning AM, Aoude LG, Wadt KA, Gerdes AM, Brown K, Hayward NK, Newton-Bishop JA, Adams DJ, Bishop DT. Germline TERT promoter mutations are rare in familial melanoma. Fam Cancer. 2016 Jan; 15(1):139-44. PMID: 26433962.
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      14. Feng Y, Pinkerton AB, Hulea L, Zhang T, Davies MA, Grotegut S, Cheli Y, Yin H, Lau E, Kim H, De SK, Barile E, Pellecchia M, Bosenberg M, Li JL, James B, Hassig CA, Brown K, Topisirovic I, Ronai ZA. SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex. Cancer Res. 2015 Dec 15; 75(24):5211-8. PMID: 26603897.
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      15. Eck BL, Fahmi R, Brown K, Zabic S, Raihani N, Miao J, Wilson DL. Computational and human observer image quality evaluation of low dose, knowledge-based CT iterative reconstruction. Med Phys. 2015 Oct; 42(10):6098. PMID: 26429285.
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      16. Law MH, Bishop DT, Lee JE, Brossard M, Martin NG, Moses EK, Song F, Barrett JH, Kumar R, Easton DF, Pharoah PD, Swerdlow AJ, Kypreou KP, Taylor JC, Harland M, Randerson-Moor J, Akslen LA, Andresen PA, Avril MF, Azizi E, Scarrà GB, Brown K, D?bniak T, Duffy DL, Elder DE, Fang S, Friedman E, Galan P, Ghiorzo P, Gillanders EM, Goldstein AM, Gruis NA, Hansson J, Helsing P, Hocevar M, Höiom V, Ingvar C, Kanetsky PA, Chen WV. Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma. Nat Genet. 2015 Sep; 47(9):987-95. PMID: 26237428.
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      17. Kim H, Frederick DT, Levesque MP, Cooper ZA, Feng Y, Krepler C, Brill L, Samuels Y, Hayward NK, Perlina A, Piris A, Zhang T, Halaban R, Herlyn MM, Brown K, Wargo JA, Dummer R, Flaherty KT, Ronai ZA. Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation. Cell Rep. 2015 Jun 9; 11(9):1458-73. PMID: 26027934.
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      18. Aoude LG, Pritchard AL, Robles-Espinoza CD, Wadt K, Harland M, Choi J, Gartside M, Quesada V, Johansson P, Palmer JM, Ramsay AJ, Zhang X, Jones K, Symmons J, Holland EA, Schmid H, Bonazzi V, Woods S, Dutton-Regester K, Stark MS, Snowden H, van Doorn R, Montgomery GW, Martin NG, Keane TM, López-Otín C, Gerdes AM, Olsson H, Ingvar C, Borg A, Gruis NA, Trent JM, Jönsson G, Bishop DT, Mann GJ, Newton-Bishop JA, Brown K, Adams DJ, Hayward NK. Nonsense Mutations in the Shelterin Complex Genes ACD and TERF2IP in Familial Melanoma. J Natl Cancer Inst. 2015 Feb; 107(2). PMID: 25505254.
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      19. Wadt KA, Aoude LG, Johansson P, Solinas A, Pritchard A, Crainic O, Andersen MT, Kiilgaard JF, Heegaard S, Sunde L, Federspiel B, Madore J, Thompson JF, McCarthy SW, Goodwin A, Tsao H, Jönsson G, Busam K, Gupta R, Trent JM, Gerdes AM, Brown K, Scolyer RA, Hayward NK. A recurrent germline BAP1 mutation and extension of the BAP1 tumor predisposition spectrum to include basal cell carcinoma. Clin Genet. 2015 Sep; 88(3):267-72. PMID: 25225168.
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      20. Noël PB, Köhler T, Fingerle AA, Brown K, Zabic S, Münzel D, Haller B, Baum T, Henninger M, Meier R, Rummeny EJ, Dobritz M. Evaluation of an iterative model-based reconstruction algorithm for low-tube-voltage (80 kVp) computed tomography angiography. J Med Imaging (Bellingham). 2014 Oct; 1(3):033501. PMID: 26158054.
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      21. Iles MM, Bishop DT, Taylor JC, Hayward NK, Brossard M, Cust AE, Dunning AM, Lee JE, Moses EK, Akslen LA. The effect on melanoma risk of genes previously associated with telomere length. J Natl Cancer Inst. 2014 Oct; 106(10). PMID: 25231748.
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      22. Ham A, Rabadi M, Kim M, Brown K, Ma Z, D'Agati V, Lee HT. Peptidyl arginine deiminase-4 activation exacerbates kidney ischemia-reperfusion injury. Am J Physiol Renal Physiol. 2014 Nov 1; 307(9):F1052-62. PMID: 25164081.
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      23. Barrett JH, Taylor JC, Bright C, Harland M, Dunning AM, Akslen LA, Andresen PA, Avril MF, Azizi E, Bianchi Scarrà G, Brossard M, Brown K, Debniak T, Elder DE, Friedman E, Ghiorzo P, Gillanders EM, Gruis NA, Hansson J, Helsing P, Hocevar M, Höiom V, Ingvar C, Landi MT, Lang J, Lathrop GM, Lubinski J, Mackie RM, Molven A, Novakovic S, Olsson H, Puig S, Puig-Butille JA, van der Stoep N, van Doorn R, van Workum W, Goldstein AM, Kanetsky PA, Pharoah PD, Demenais F, Hayward NK, Newton Bishop JA, Bishop DT, Iles MM. Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions. Int J Cancer. 2015 Mar 15; 136(6):1351-60. PMID: 25077817.
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      24. Song F, Amos CI, Lee JE, Lian CG, Fang S, Liu H, MacGregor S, Iles MM, Law MH, Lindeman NI, Montgomery GW, Duffy DL, Cust AE, Jenkins MA, Whiteman DC, Kefford RF, Giles GG, Armstrong BK, Aitken JF, Hopper JL, Brown K, Martin NG, Mann GJ, Bishop DT, Bishop JA. Identification of a melanoma susceptibility locus and somatic mutation in TET2. Carcinogenesis. 2014 Sep; 35(9):2097-101. PMID: 24980573.
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      25. Aoude LG, Xu M, Zhao ZZ, Kovacs M, Palmer JM, Johansson P, Symmons J, Trent JM, Martin NG, Montgomery GW, Brown K, Hayward NK. Assessment of PALB2 as a Candidate Melanoma Susceptibility Gene. PLoS One. 2014; 9(6):e100683. PMID: 24949998.
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      26. Kim M, Ham A, Kim KY, Brown K, Lee HT. The Volatile Anesthetic Isoflurane Increases Endothelial Adenosine Generation via Microparticle Ecto-5'-Nucleotidase (CD73) Release. PLoS One. 2014; 9(6):e99950. PMID: 24945528.
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      27. Shen B, Brown K, Lee TD, Sibley LD. Efficient Gene Disruption in Diverse Strains of Toxoplasma gondii Using CRISPR/CAS9. MBio. 2014; 5(3). PMID: 24825012.
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      28. Farrell A, Coleman BI, Benenati B, Brown K, Blader IJ, Marth GT, Gubbels MJ. Whole genome profiling of spontaneous and chemically induced mutations in Toxoplasma gondii. BMC Genomics. 2014; 15:354. PMID: 24885922.
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      29. Robles-Espinoza CD, Harland M, Ramsay AJ, Aoude LG, Quesada V, Ding Z, Pooley KA, Pritchard AL, Tiffen JC, Petljak M, Palmer JM, Symmons J, Johansson P, Stark MS, Gartside MG, Snowden H, Montgomery GW, Martin NG, Liu JZ, Choi J, Makowski M, Brown K, Dunning AM, Keane TM, López-Otín C, Gruis NA, Hayward NK, Bishop DT, Newton-Bishop JA, Adams DJ. POT1 loss-of-function variants predispose to familial melanoma. Nat Genet. 2014 May; 46(5):478-81. PMID: 24686849.
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      30. Ham A, Kim M, Kim JY, Brown K, Yeh J, D'Agati VD, Lee HT. Critical Role of Interleukin-11 in Isoflurane-mediated Protection against Ischemic Acute Kidney Injury in Mice. Anesthesiology. 2013 Dec; 119(6):1389-401. PMID: 24037316.
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      31. Ham A, Kim M, Kim JY, Brown K, Fruttiger M, D'Agati VD, Thomas Lee H. Selective deletion of the endothelial sphingosine-1-phosphate 1 receptor exacerbates kidney ischemia-reperfusion injury. Kidney Int. 2014 Apr; 85(4):807-23. PMID: 24025642.
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      32. Aoude LG, Wadt K, Bojesen A, Crüger D, Borg A, Trent JM, Brown K, Gerdes AM, Jönsson G, Hayward NK. A BAP1 mutation in a Danish family predisposes to uveal melanoma and other cancers. PLoS One. 2013; 8(8):e72144. PMID: 23977234.
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      33. Kim JY, Kim M, Ham A, Brown K, Greene RW, D'Agati VD, Lee HT. IL-11 is required for A1 adenosine receptor-mediated protection against ischemic AKI. J Am Soc Nephrol. 2013 Oct; 24(10):1558-70. PMID: 23813214.
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      34. Iles MM, Law MH, Stacey SN, Han J, Fang S, Pfeiffer R, Harland M, Macgregor S, Taylor JC, Aben KK, Akslen LA, Avril MF, Azizi E, Bakker B, Benediktsdottir KR, Bergman W, Scarrà GB, Brown K, Calista D, Chaudru V, Fargnoli MC, Cust AE, Demenais F, de Waal AC, Debniak T, Elder DE, Friedman E, Galan P, Ghiorzo P, Gillanders EM, Goldstein AM, Gruis NA, Hansson J, Helsing P, Hocevar M, Höiom V, Hopper JL, Ingvar C, Janssen M, Jenkins MA, Kanetsky PA, Kiemeney LA, Lang J, Lathrop GM, Leachman S, Lee JE, Lubinski J, Mackie RM, Mann GJ, Martin NG, Mayordomo JI, Molven A, Mulder S, Nagore E, Novakovic S, Okamoto I, Olafsson JH, Olsson H, Pehamberger H, Peris K, Grasa MP, Planelles D, Puig S, Puig-Butille JA, Randerson-Moor J, Requena C, Rivoltini L, Rodolfo M, Santinami M, Sigurgeirsson B, Snowden H, Song F, Sulem P, Thorisdottir K, Tuominen R, Van Belle P, van der Stoep N, van Rossum MM, Wei Q, Wendt J, Zelenika D, Zhang M, Landi MT, Thorleifsson G, Bishop DT, Amos CI, Hayward NK, Stefansson K, Bishop JA, Barrett JH. A variant in FTO shows association with melanoma risk not due to BMI. Nat Genet. 2013 Apr; 45(4):428-32, 432e1. PMID: 23455637.
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      35. Zabic S, Wang Q, Morton T, Brown K. A low dose simulation tool for CT systems with energy integrating detectors. Med Phys. 2013 Mar; 40(3):031102. PMID: 23464282.
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      36. Kim M, Ham A, Kim JY, Brown K, D'Agati VD, Lee HT. The volatile anesthetic isoflurane induces ecto-5'-nucleotidase (CD73) to protect against renal ischemia and reperfusion injury. Kidney Int. 2013 Jul; 84(1):90-103. PMID: 23423261.
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      37. Lee HT, Kim M, Kim JY, Brown K, Ham A, D'Agati VD, Mori-Akiyama Y. Critical role of interleukin-17A in murine intestinal ischemia-reperfusion injury. Am J Physiol Gastrointest Liver Physiol. 2013 Jan 1; 304(1):G12-25. PMID: 23125155.
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      38. Park SW, Kim M, Kim JY, Ham A, Brown K, Mori-Akiyama Y, Ouellette AJ, D'Agati VD, Lee HT. Paneth cell-mediated multiorgan dysfunction after acute kidney injury. J Immunol. 2012 Dec 1; 189(11):5421-33. PMID: 23109723.
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      39. Wadt K, Choi J, Chung JY, Kiilgaard J, Heegaard S, Drzewiecki KT, Trent JM, Hewitt SM, Hayward NK, Gerdes AM, Brown K. A cryptic BAP1 splice mutation in a family with uveal and cutaneous melanoma, and paraganglioma. Pigment Cell Melanoma Res. 2012 Nov; 25(6):815-8. PMID: 22889334.
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      40. Brown K, Fialko Y. 'Melt welt' mechanism of extreme weakening of gabbro at seismic slip rates. Nature. 2012 Aug 30; 488(7413):638-41. PMID: 22932388.
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      41. Lee HT, Park SW, Kim M, Ham A, Anderson LJ, Brown K, D'Agati VD, Cox GN. Interleukin-11 protects against renal ischemia and reperfusion injury. Am J Physiol Renal Physiol. 2012 Oct 15; 303(8):F1216-24. PMID: 22859402.
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      42. Park SW, Kim JY, Ham A, Brown K, Kim M, D'Agati VD, Lee HT. A1 adenosine receptor allosteric enhancer PD-81723 protects against renal ischemia-reperfusion injury. Am J Physiol Renal Physiol. 2012 Sep; 303(5):F721-32. PMID: 22759398.
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      43. Park SW, Kim M, Kim JY, Brown K, Haase VH, D'Agati VD, Lee HT. Proximal tubule sphingosine kinase-1 has a critical role in A1 adenosine receptor-mediated renal protection from ischemia. Kidney Int. 2012 Oct; 82(8):878-91. PMID: 22695326.
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      44. Xu Y, Brown K, Wang ZA, van der Wel H, Teygong C, Zhang D, Blader IJ, West CM. The Skp1 protein from Toxoplasma is modified by a cytoplasmic prolyl 4-hydroxylase associated with oxygen sensing in the social amoeba Dictyostelium. J Biol Chem. 2012 Jul 20; 287(30):25098-110. PMID: 22648409.
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      45. Sriram KB, Larsen JE, Savarimuthu Francis SM, Wright CM, Clarke BE, Duhig EE, Brown K, Hayward NK, Yang IA, Bowman RV, Fong KM. Array-comparative genomic hybridization reveals loss of SOCS6 is associated with poor prognosis in primary lung squamous cell carcinoma. PLoS One. 2012; 7(2):e30398. PMID: 22363434.
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      46. Stark MS, Woods SL, Gartside MG, Bonazzi VF, Dutton-Regester K, Aoude LG, Chow D, Sereduk C, Niemi NM, Tang N, Ellis JJ, Reid J, Zismann V, Tyagi S, Muzny D, Newsham I, Wu Y, Palmer JM, Pollak T, Youngkin D, Brooks BR, Lanagan C, Schmidt CW, Kobe B, MacKeigan JP, Yin H, Brown K, Gibbs R, Trent J, Hayward NK. Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing. Nat Genet. 2012 Feb; 44(2):165-9. PMID: 22197930.
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      47. Park SW, Kim M, Brown K, D'Agati VD, Lee HT. Inhibition of sphingosine 1-phosphate receptor 2 protects against renal ischemia-reperfusion injury. J Am Soc Nephrol. 2012 Feb; 23(2):266-80. PMID: 22095950.
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      48. Yokoyama S, Woods SL, Boyle GM, Aoude LG, MacGregor S, Zismann V, Gartside M, Cust AE, Haq R, Harland M, Taylor JC, Duffy DL, Holohan K, Dutton-Regester K, Palmer JM, Bonazzi V, Stark MS, Symmons J, Law MH, Schmidt C, Lanagan C, O'Connor L, Holland EA, Schmid H, Maskiell JA, Jetann J, Ferguson M, Jenkins MA, Kefford RF, Giles GG, Armstrong BK, Aitken JF, Hopper JL, Whiteman DC, Pharoah PD, Easton DF, Dunning AM, Newton-Bishop JA, Montgomery GW, Martin NG, Mann GJ, Bishop DT, Tsao H, Trent JM, Fisher DE, Hayward NK, Brown K. A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature. 2011 Dec 1; 480(7375):99-103. PMID: 22080950.
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      49. Law MH, Montgomery GW, Brown K, Martin NG, Mann GJ, Hayward NK, MacGregor S. Meta-analysis combining new and existing data sets confirms that the TERT-CLPTM1L locus influences melanoma risk. J Invest Dermatol. 2012 Feb; 132(2):485-7. PMID: 21993562.
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      50. Barrett JH, Iles MM, Harland M, Taylor JC, Aitken JF, Andresen PA, Akslen LA, Armstrong BK, Avril MF, Azizi E, Bakker B, Bergman W, Bianchi-Scarrà G, Bressac-de Paillerets B, Calista D, Cannon-Albright LA, Corda E, Cust AE, Debniak T, Duffy D, Dunning AM, Easton DF, Friedman E, Galan P, Ghiorzo P, Giles GG, Hansson J, Hocevar M, Höiom V, Hopper JL, Ingvar C, Janssen B, Jenkins MA, Jönsson G, Kefford RF, Landi G, Landi MT, Lang J, Lubinski J, Mackie R, Malvehy J, Martin NG, Molven A, Montgomery GW, van Nieuwpoort FA, Novakovic S, Olsson H, Pastorino L, Puig S, Puig-Butille JA, Randerson-Moor J, Snowden H, Tuominen R, Van Belle P, van der Stoep N, Whiteman DC, Zelenika D, Han J, Fang S, Lee JE, Wei Q, Lathrop GM, Gillanders EM, Brown K, Goldstein AM, Kanetsky PA, Mann GJ, Macgregor S, Elder DE, Amos CI, Hayward NK, Gruis NA, Demenais F, Bishop JA, Bishop DT. Genome-wide association study identifies three new melanoma susceptibility loci. Nat Genet. 2011 Nov; 43(11):1108-13. PMID: 21983787.
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      51. Macgregor S, Montgomery GW, Liu JZ, Zhao ZZ, Henders AK, Stark M, Schmid H, Holland EA, Duffy DL, Zhang M, Painter JN, Nyholt DR, Maskiell JA, Jetann J, Ferguson M, Cust AE, Jenkins MA, Whiteman DC, Olsson H, Puig S, Bianchi-Scarrà G, Hansson J, Demenais F, Landi MT, Debniak T, Mackie R, Azizi E, Bressac-de Paillerets B, Goldstein AM, Kanetsky PA, Gruis NA, Elder DE, Newton-Bishop JA, Bishop DT, Iles MM, Helsing P, Amos CI, Wei Q, Wang LE, Lee JE, Qureshi AA, Kefford RF, Giles GG, Armstrong BK, Aitken JF, Han J, Hopper JL, Trent JM, Brown K, Martin NG, Mann GJ, Hayward NK. Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3. Nat Genet. 2011 Nov; 43(11):1114-8. PMID: 21983785.
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      52. Amos CI, Wang LE, Lee JE, Gershenwald JE, Chen WV, Fang S, Kosoy R, Zhang M, Qureshi AA, Vattathil S, Schacherer CW, Gardner JM, Wang Y, Bishop DT, Barrett JH. Genome-wide association study identifies novel loci predisposing to cutaneous melanoma. Hum Mol Genet. 2011 Dec 15; 20(24):5012-23. PMID: 21926416.
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      53. Park SW, Kim M, Brown K, D'Agati VD, Lee HT. Paneth cell-derived interleukin-17A causes multiorgan dysfunction after hepatic ischemia and reperfusion injury. Hepatology. 2011 May; 53(5):1662-75. PMID: 21360570.
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      54. Park SW, Chen SW, Kim M, Brown K, Kolls JK, D'Agati VD, Lee HT. Cytokines induce small intestine and liver injury after renal ischemia or nephrectomy. Lab Invest. 2011 Jan; 91(1):63-84. PMID: 20697374.
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      62. Skibola CF, Bracci PM, Halperin E, Conde L, Craig DW, Agana L, Iyadurai K, Becker N, Brooks-Wilson A, Curry JD, Spinelli JJ, Holly EA, Riby J, Zhang L, Nieters A, Smith MT, Brown K. Genetic variants at 6p21.33 are associated with susceptibility to follicular lymphoma. Nat Genet. 2009 Aug; 41(8):873-5. PMID: 19620980.
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      63. Bishop DT, Demenais F, Iles MM, Harland M, Taylor JC, Corda E, Randerson-Moor J, Aitken JF, Avril MF, Azizi E, Bakker B, Bianchi-Scarrà G, Bressac-de Paillerets B, Calista D, Cannon-Albright LA, Chin-A-Woeng T, Debniak T, Galore-Haskel G, Ghiorzo P, Gut I, Hansson J, Hocevar M, Höiom V, Hopper JL, Ingvar C, Kanetsky PA, Kefford RF, Landi MT, Lang J, Lubinski J, Mackie R, Malvehy J, Mann GJ, Martin NG, Montgomery GW, van Nieuwpoort FA, Novakovic S, Olsson H, Puig S, Weiss M, van Workum W, Zelenika D, Brown K, Goldstein AM, Gillanders EM, Boland A, Galan P, Elder DE, Gruis NA, Hayward NK, Lathrop GM, Barrett JH, Bishop JA. Genome-wide association study identifies three loci associated with melanoma risk. Nat Genet. 2009 Aug; 41(8):920-5. PMID: 19578364.
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      69. Seftor EA, Brown K, Chin L, Kirschmann DA, Wheaton WW, Protopopov A, Feng B, Balagurunathan Y, Trent JM, Nickoloff BJ, Seftor RE, Hendrix MJ. Epigenetic transdifferentiation of normal melanocytes by a metastatic melanoma microenvironment. Cancer Res. 2005 Nov 15; 65(22):10164-9. PMID: 16288000.
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      77. Laverack GR, Brown K. Qualitative research in a cross-cultural context: Fijian experiences. Qual Health Res. 2003 Mar; 13(3):333-42. PMID: 12669335.
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      79. Eastwood H, Brown K, Markovic D, Pieri LF. Variation in the ESR1 and ESR2 genes and genetic susceptibility to anorexia nervosa. Mol Psychiatry. 2002; 7(1):86-9. PMID: 11803451.
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      80. Devaney JM, Donarum EA, Brown K, Meyer J, Stöber G, Lesch KP, Nestadt G, Stephan DA, Pulver AE. No missense mutation of WKL1 in a subgroup of probands with schizophrenia. Mol Psychiatry. 2002; 7(4):419-23. PMID: 11986987.
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      81. Koul RL, Chand RP, Chacko A, Ali M, Brown K, Bushnarmuth SR, Escolar DM, Stephan DA. Severe autosomal recessive rippling muscle disease. Muscle Nerve. 2001 Nov; 24(11):1542-7. PMID: 11745958.
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      82. MacDonald TJ, Brown K, LaFleur B, Peterson K, Lawlor C, Chen Y, Packer RJ, Cogen P, Stephan DA. Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease. Nat Genet. 2001 Oct; 29(2):143-52. PMID: 11544480.
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      83. Papaconstantinou AD, Fisher BR, Umbreit TH, Goering PL, Lappas NT, Brown K. Effects of beta-estradiol and bisphenol A on heat shock protein levels and localization in the mouse uterus are antagonized by the antiestrogen ICI 182,780. Toxicol Sci. 2001 Oct; 63(2):173-80. PMID: 11568360.
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      84. Laitinen PJ, Brown K, Piippo K, Swan H, Devaney JM, Brahmbhatt B, Donarum EA, Marino M, Tiso N, Viitasalo M, Toivonen L, Stephan DA, Kontula K. Mutations of the cardiac ryanodine receptor (RyR2) gene in familial polymorphic ventricular tachycardia. Circulation. 2001 Jan 30; 103(4):485-90. PMID: 11157710.
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      85. Lavigne JV, Brown K, Gidding S, Evans M, Stevens VJ, von Almen TK, Ewart C, Weil C. A cholesterol-lowering diet does not produce adverse psychological effects in children: three-year results from the dietary intervention study in children. Health Psychol. 1999 Nov; 18(6):604-13. PMID: 10619534.
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      86. Trinh DP, Brown K, Jeang KT. Epithelin/granulin growth factors: extracellular cofactors for HIV-1 and HIV-2 Tat proteins. Biochem Biophys Res Commun. 1999 Mar 16; 256(2):299-306. PMID: 10079180.
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      87. Reimers TM, Brown K, Van Horn L, Stevens V, Obarzanek E, Hartmuller VW, Snetselaar L, von Almen TK, Chiostri J. Maternal acceptability of a dietary intervention designed to lower children's intake of saturated fat and cholesterol: the Dietary Intervention Study in Children (DISC). J Am Diet Assoc. 1998 Jan; 98(1):31-4. PMID: 9434647.
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      88. Abbaszadegan MR, Struewing JP, Brown K, Snider JV, Goodsaid F, Gore-Langton R, Hughes MR. Automated detection of prevalent mutations in BRCA1 and BRCA2 genes, using a fluorogenic PCR allelic discrimination assay. Genet Test. 1997-1998; 1(3):171-80. PMID: 10464643.
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      89. Packer RK, Curry CA, Brown K. Urinary organic anion excretion in response to dietary acid and base loading. J Am Soc Nephrol. 1995 Feb; 5(8):1624-9. PMID: 7756596.
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      90. Marriott SJ, Lindholm PF, Brown K, Gitlin SD, Duvall JF, Radonovich MF, Brady JN. A 36-kilodalton cellular transcription factor mediates an indirect interaction of human T-cell leukemia/lymphoma virus type I TAX1 with a responsive element in the viral long terminal repeat. Mol Cell Biol. 1990 Aug; 10(8):4192-201. PMID: 2370863; PMCID: PMC360951.
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