Our site may be slower due to heavy traffic from automated "bots" and AI crawlers. We're working to fix this.

Lalit Deshmukh

Title(s)Associate Professor, Chemistry and Biochemistry
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Quantitative Characterization of Chain-Flipping of Acyl Carrier Protein of Escherichia coli Using Chemical Exchange NMR. J Am Chem Soc. 2024 Jul 10; 146(27):18650-18660. Kalaj BN, La Clair JJ, Shen Y, Schwieters CD, Deshmukh L, Burkart MD. PMID: 38875499; PMCID: PMC11299499.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    2. Phase Separation and Fibrillization of Human Annexin A7 Are Mediated by Its Proline-Rich Domain. Biochemistry. 2023 11 07; 62(21):3036-3040. Yu C, Nelson SL, Meisl G, Ghirlando R, Deshmukh L. PMID: 37788367; PMCID: PMC10634317.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Reversible phase separation of ESCRT protein ALIX through tyrosine phosphorylation. Sci Adv. 2023 07 14; 9(28):eadg3913. Elias RD, Zhu Y, Su Q, Ghirlando R, Zhang J, Deshmukh L. PMID: 37450591; PMCID: PMC10348681.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    4. ALS Variants of Annexin A11's Proline-Rich Domain Impair Its S100A6-Mediated Fibril Dissolution. ACS Chem Neurosci. 2023 08 02; 14(15):2583-2589. Shihora A, Elias RD, Hammond JA, Ghirlando R, Deshmukh L. PMID: 37433222; PMCID: PMC10401653.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    5. Avidity-Based Method for the Efficient Generation of Monoubiquitinated Recombinant Proteins. J Am Chem Soc. 2023 04 12; 145(14):7748-7752. Nelson SL, Li Y, Chen Y, Deshmukh L. PMID: 37010382; PMCID: PMC10103170.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    6. Mechanistic roles of tyrosine phosphorylation in reversible amyloids, autoinhibition, and endosomal membrane association of ALIX. J Biol Chem. 2021 11; 297(5):101328. Elias RD, Ramaraju B, Deshmukh L. PMID: 34688656; PMCID: PMC8577116.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    7. Quantitative NMR Study of Insulin-Degrading Enzyme Using Amyloid-β and HIV-1 p6 Elucidates Its Chaperone Activity. Biochemistry. 2021 08 24; 60(33):2519-2523. Ramaraju B, Nelson SL, Zheng W, Ghirlando R, Deshmukh L. PMID: 34342986; PMCID: PMC8895387.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    8. Proline-rich domain of human ALIX contains multiple TSG101-UEV interaction sites and forms phosphorylation-mediated reversible amyloids. Proc Natl Acad Sci U S A. 2020 09 29; 117(39):24274-24284. Elias RD, Ma W, Ghirlando R, Schwieters CD, Reddy VS, Deshmukh L. PMID: 32917811; PMCID: PMC7533887.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    9. Inhibition of HIV Maturation via Selective Unfolding and Cross-Linking of Gag Polyprotein by a Mercaptobenzamide Acetylator. J Am Chem Soc. 2019 05 22; 141(20):8327-8338. Miller Jenkins LM, Paine EL, Deshmukh L, Nikolayevskiy H, Lyons GC, Scerba MT, George Rosenker K, Luecke HF, Louis JM, Chertova E, Gorelick RJ, Ott DE, Clore GM, Appella DH. PMID: 31042030; PMCID: PMC8496520.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    10. Targeting a Dark Excited State of HIV-1 Nucleocapsid by Antiretroviral Thioesters Revealed by NMR Spectroscopy. Angew Chem Int Ed Engl. 2018 03 01; 57(10):2687-2691. Deshmukh L, Tugarinov V, Appella DH, Clore GM. PMID: 29345807; PMCID: PMC6034507.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    11. Binding kinetics and substrate selectivity in HIV-1 protease-Gag interactions probed at atomic resolution by chemical exchange NMR. Proc Natl Acad Sci U S A. 2017 11 14; 114(46):E9855-E9862. Deshmukh L, Tugarinov V, Louis JM, Clore GM. PMID: 29087351; PMCID: PMC5699096.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    12. Transient HIV-1 Gag-protease interactions revealed by paramagnetic NMR suggest origins of compensatory drug resistance mutations. Proc Natl Acad Sci U S A. 2016 11 01; 113(44):12456-12461. Deshmukh L, Louis JM, Ghirlando R, Clore GM. PMID: 27791180; PMCID: PMC5098610.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    13. Quantitative Characterization of Configurational Space Sampled by HIV-1 Nucleocapsid Using Solution NMR, X-ray Scattering and Protein Engineering. Chemphyschem. 2016 06 03; 17(11):1548-52. Deshmukh L, Schwieters CD, Grishaev A, Clore GM. PMID: 26946052; PMCID: PMC5590652.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    14. Mutations Proximal to Sites of Autoproteolysis and the α-Helix That Co-evolve under Drug Pressure Modulate the Autoprocessing and Vitality of HIV-1 Protease. Biochemistry. 2015 Sep 08; 54(35):5414-24. Louis JM, Deshmukh L, Sayer JM, Aniana A, Clore GM. PMID: 26266692; PMCID: PMC5590646.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    15. Conformation and dynamics of the Gag polyprotein of the human immunodeficiency virus 1 studied by NMR spectroscopy. Proc Natl Acad Sci U S A. 2015 Mar 17; 112(11):3374-9. Deshmukh L, Ghirlando R, Clore GM. PMID: 25713345; PMCID: PMC4371905.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    16. Skelemin association with αIIbβ3 integrin: a structural model. Biochemistry. 2014 Nov 04; 53(43):6766-75. Gorbatyuk V, Nguyen K, Podolnikova NP, Deshmukh L, Lin X, Ugarova TP, Vinogradova O. PMID: 25224262; PMCID: PMC4222533.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    17. Investigation of the structure and dynamics of the capsid-spacer peptide 1-nucleocapsid fragment of the HIV-1 gag polyprotein by solution NMR spectroscopy. Angew Chem Int Ed Engl. 2014 Jan 20; 53(4):1025-8. Deshmukh L, Ghirlando R, Clore GM. PMID: 24338988; PMCID: PMC4049115.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    18. Structure and dynamics of full-length HIV-1 capsid protein in solution. J Am Chem Soc. 2013 Oct 30; 135(43):16133-47. Deshmukh L, Schwieters CD, Grishaev A, Ghirlando R, Baber JL, Clore GM. PMID: 24066695; PMCID: PMC3946434.
      View in: PubMed   Mentions: 75     Fields:    Translation:Cells
    19. Integrin β3 crosstalk with VEGFR accommodating tyrosine phosphorylation as a regulatory switch. PLoS One. 2012; 7(2):e31071. West XZ, Meller N, Malinin NL, Deshmukh L, Meller J, Mahabeleshwar GH, Weber ME, Kerr BA, Vinogradova O, Byzova TV. PMID: 22363548; PMCID: PMC3281915.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    20. Structural studies of a signal peptide in complex with signal peptidase I cytoplasmic domain: the stabilizing effect of membrane-mimetics on the acquired fold. Proteins. 2012 Mar; 80(3):807-17. De Bona P, Deshmukh L, Gorbatyuk V, Vinogradova O, Kendall DA. PMID: 22113858; PMCID: PMC3277640.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    21. Tyrosine phosphorylation as a conformational switch: a case study of integrin β3 cytoplasmic tail. J Biol Chem. 2011 Nov 25; 286(47):40943-53. Deshmukh L, Meller N, Alder N, Byzova T, Vinogradova O. PMID: 21956114; PMCID: PMC3220520.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    22. Integrin {beta}3 phosphorylation dictates its complex with the Shc phosphotyrosine-binding (PTB) domain. J Biol Chem. 2010 Nov 05; 285(45):34875-84. Deshmukh L, Gorbatyuk V, Vinogradova O. PMID: 20739287; PMCID: PMC2966102.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    23. NMR solution structure of human cannabinoid receptor-1 helix 7/8 peptide: candidate electrostatic interactions and microdomain formation. Biochem Biophys Res Commun. 2009 Dec 18; 390(3):441-6. Tyukhtenko S, Tiburu EK, Deshmukh L, Vinogradova O, Janero DR, Makriyannis A. PMID: 19766594; PMCID: PMC3679914.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    24. The solution structure of Bacillus anthracis dihydrofolate reductase yields insight into the analysis of structure-activity relationships for novel inhibitors. Biochemistry. 2009 May 19; 48(19):4100-8. Beierlein JM, Deshmukh L, Frey KM, Vinogradova O, Anderson AC. PMID: 19323450; PMCID: PMC2810191.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    25. Structural biology of human cannabinoid receptor-2 helix 6 in membrane-mimetic environments. Biochem Biophys Res Commun. 2009 Jun 26; 384(2):243-8. Tiburu EK, Tyukhtenko S, Deshmukh L, Vinogradova O, Janero DR, Makriyannis A. PMID: 19397896; PMCID: PMC3679894.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    26. NMR structural characterization of the penta-peptide calpain inhibitor. FEBS Lett. 2009 Jan 05; 583(1):135-40. Deshmukh L, Wu L, Guttmann RP, Vinogradova O. PMID: 19059407.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    27. Characterization of the neuron-specific L1-CAM cytoplasmic tail: naturally disordered in solution it exercises different binding modes for different adaptor proteins. Biochemistry. 2008 Apr 01; 47(13):4160-8. Tyukhtenko S, Deshmukh L, Kumar V, Lary J, Cole J, Lemmon V, Vinogradova O. PMID: 18321067; PMCID: PMC2426742.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    28. Structural insight into the interaction between platelet integrin alphaIIbbeta3 and cytoskeletal protein skelemin. J Biol Chem. 2007 Nov 02; 282(44):32349-56. Deshmukh L, Tyukhtenko S, Liu J, Fox JE, Qin J, Vinogradova O. PMID: 17804417.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    Lalit's Networks
    Concepts (138)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (3)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCSD Profiles is managed by the UC San Diego Altman Clinical and Translational Research Institute (ACTRI).
    This site is running Profiles RNS version UCSF-v3.1.0-16-gff1bd585 on PROFILES-PWEB04. We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use.

    Copyright © The Regents of the University of California