Harrison Penrose

Title(s)Resident Physician, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    University of California, San Diego, La Jolla, CAInternal Medicine
    Tulane University School of Medicine, New Orleans, LAMD, PhD05/2021Medicine
    University of California, San Diego, La Jolla, CAMS06/2012General Biology
    University of California, San Diego, La Jolla, CABS06/2011Biochemistry & Cell Biology

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. FOXO3 Expression in Macrophages Is Lowered by a High-Fat Diet and Regulates Colonic Inflammation and Tumorigenesis. Metabolites. 2022 Mar 16; 12(3). Iftikhar R, Penrose HM, King AN, Kim Y, Ruiz E, Kandil E, Machado HL, Savkovic SD. PMID: 35323693; PMCID: PMC8949544.
      View in: PubMed   Mentions:
    2. Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity. Oncogenesis. 2021 Nov 29; 10(11):82. Iftikhar R, Penrose HM, King AN, Samudre JS, Collins ME, Hartono AB, Lee SB, Lau F, Baddoo M, Flemington EF, Crawford SE, Savkovic SD. PMID: 34845203; PMCID: PMC8630180.
      View in: PubMed   Mentions: 1  
    3. Trends in the Incidence of Early-Onset Colorectal Adenocarcinoma Among Black and White US Residents Aged 40 to 49 Years, 2000-2017. JAMA Netw Open. 2021 11 01; 4(11):e2130433. Montminy EM, Zhou M, Maniscalco L, Penrose H, Yen T, Patel SG, Wu XC, Karlitz JJ. PMID: 34751760; PMCID: PMC8579235.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. Ulcerative colitis immune cell landscapes and differentially expressed gene signatures determine novel regulators and predict clinical response to biologic therapy. Sci Rep. 2021 04 27; 11(1):9010. Penrose HM, Iftikhar R, Collins ME, Toraih E, Ruiz E, Ungerleider N, Nakhoul H, Flemington EF, Kandil E, Shah SB, Savkovic SD. PMID: 33907256; PMCID: PMC8079702.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    5. STAT1 regulates interferon-γ-induced angiotensinogen and MCP-1 expression in a bidirectional manner in primary cultured mesangial cells. J Renin Angiotensin Aldosterone Syst. 2020 Jul-Sep; 21(3):1470320320946527. Penrose HM, Katsurada A, Miyata K, Urushihara M, Satou R. PMID: 32741247; PMCID: PMC7412908.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    6. Bacterial TLR4 and NOD2 signaling linked to reduced mitochondrial energy function in active inflammatory bowel disease. Gut Microbes. 2020 05 03; 11(3):350-363. Ruiz E, Penrose HM, Heller S, Nakhoul H, Baddoo M, Flemington EF, Kandil E, Savkovic SD. PMID: 31063017; PMCID: PMC7524318.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    7. Loss of Forkhead Box O3 Facilitates Inflammatory Colon Cancer: Transcriptome Profiling of the Immune Landscape and Novel Targets. Cell Mol Gastroenterol Hepatol. 2019; 7(2):391-408. Penrose HM, Cable C, Heller S, Ungerleider N, Nakhoul H, Baddoo M, Hartono AB, Lee SB, Burow ME, Flemington EF, Crawford SE, Savkovic SD. PMID: 30718226; PMCID: PMC6360252.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    8. Inflammation as a Regulator of the Renin-Angiotensin System and Blood Pressure. Curr Hypertens Rep. 2018 10 05; 20(12):100. Satou R, Penrose H, Navar LG. PMID: 30291560; PMCID: PMC6203444.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    9. In colonic ρ0 (rho0) cells reduced mitochondrial function mediates transcriptomic alterations associated with cancer. Oncoscience. 2017 Nov; 4(11-12):189-198. Penrose HM, Heller S, Cable C, Nakhoul H, Ungerleider N, Baddoo M, Pursell ZF, Flemington EK, Crawford SE, Savkovic SD. PMID: 29344557; PMCID: PMC5769983.
      View in: PubMed   Mentions: 5  
    10. High-fat diet induced leptin and Wnt expression: RNA-sequencing and pathway analysis of mouse colonic tissue and tumors. Carcinogenesis. 2017 03 01; 38(3):302-311. Penrose HM, Heller S, Cable C, Nakhoul H, Baddoo M, Flemington E, Crawford SE, Savkovic SD. PMID: 28426873; PMCID: PMC5862315.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    11. Reduced mitochondrial activity in colonocytes facilitates AMPKα2-dependent inflammation. FASEB J. 2017 05; 31(5):2013-2025. Heller S, Penrose HM, Cable C, Biswas D, Nakhoul H, Baddoo M, Flemington E, Crawford SE, Savkovic SD. PMID: 28183804; PMCID: PMC5388551.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    12. VSL#3 Probiotic Stimulates T-cell Protein Tyrosine Phosphatase-mediated Recovery of IFN-γ-induced Intestinal Epithelial Barrier Defects. Inflamm Bowel Dis. 2016 12; 22(12):2811-2823. Krishnan M, Penrose HM, Shah NN, Marchelletta RR, McCole DF. PMID: 27824650; PMCID: PMC5779620.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    13. Macrophage-derived IL-6 contributes to ANG II-mediated angiotensinogen stimulation in renal proximal tubular cells. Am J Physiol Renal Physiol. 2016 05 15; 310(10):F1000-7. O'Leary R, Penrose H, Miyata K, Satou R. PMID: 27009340; PMCID: PMC4983453.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    14. Intestinal inflammation requires FOXO3 and prostaglandin E2-dependent lipogenesis and elevated lipid droplets. Am J Physiol Gastrointest Liver Physiol. 2016 05 15; 310(10):G844-54. Heller S, Cable C, Penrose H, Makboul R, Biswas D, Cabe M, Crawford SE, Savkovic SD. PMID: 26968210; PMCID: PMC4895869.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    15. Epidermal growth factor receptor mediated proliferation depends on increased lipid droplet density regulated via a negative regulatory loop with FOXO3/Sirtuin6. Biochem Biophys Res Commun. 2016 Jan 15; 469(3):370-6. Penrose H, Heller S, Cable C, Makboul R, Chadalawada G, Chen Y, Crawford SE, Savkovic SD. PMID: 26657850; PMCID: PMC5607009.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    16. A comparison of linaclotide and lubiprostone dosing regimens on ion transport responses in human colonic mucosa. Pharmacol Res Perspect. 2015 Mar; 3(2):e00128. Kang SB, Marchelletta RR, Penrose H, Docherty MJ, McCole DF. PMID: 26038704; PMCID: PMC4448989.
      View in: PubMed   Mentions: 1     Fields:    
    17. Spermidine stimulates T cell protein-tyrosine phosphatase-mediated protection of intestinal epithelial barrier function. J Biol Chem. 2013 Nov 08; 288(45):32651-32662. Penrose HM, Marchelletta RR, Krishnan M, McCole DF. PMID: 24022492; PMCID: PMC3820900.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
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