Gaurav Syal

Title(s)Associate Clinical Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    1. Pre-operative visceral adipose tissue radiodensity is a potentially novel prognostic biomarker for early endoscopic post-operative recurrence in Crohn's disease. World J Gastrointest Surg. 2024 Mar 27; 16(3):740-750. Gu P, Dube S, Gellada N, Choi SY, Win S, Lee YJ, Yang S, Haritunians T, Melmed GY, Vasiliauskas EA, Bonthala N, Syal G, Yarur AJ, Ziring D, Rabizadeh S, Fleshner P, Kallman C, Devkota S, Targan SR, Li D, McGovern DP. PMID: 38577075; PMCID: PMC10989343.
      View in: PubMed   Mentions:
    2. Real-World Effectiveness of Ustekinumab in Ulcerative Colitis in a United States Multicenter Cohort Consortium. Inflamm Bowel Dis. 2024 Mar 26. Yarur AJ, Ungaro R, Huang K, Wang W, Sasankan P, Zulqarnain M, Johnson AM, Bader G, Kay C, Costable N, Dulaney D, Fenster M, Beniwal-Patel P, Syal G, Patel A, Loftus E, Pekow J, Cohen B, Deepak P. PMID: 38531068.
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    3. Comprehensive Association Analyses of Extraintestinal Manifestations in Inflammatory Bowel Disease. Gastroenterology. 2024 Mar 13. Khrom M, Long M, Dube S, Robbins L, Botwin GJ, Yang S, Mengesha E, Li D, Naito T, Bonthala NN, Ha C, Melmed G, Rabizadeh S, Syal G, Vasiliauskas E, Ziring D, Brant SR, Cho J, Duerr RH, Rioux J, Schumm P, Silverberg M, Ananthakrishnan AN, Faubion WA, Jabri B, Lira SA, Newberry RD, Sandler RS, Xavier RJ, Kugathasan S, Hercules D, Targan SR, Sartor RB, Haritunians T, McGovern DPB. PMID: 38490347.
      View in: PubMed   Mentions:    Fields:    
    4. Impact of Treatment Response on Risk of Serious Infections in Patients With Crohn's Disease: Secondary Analysis of the PYRAMID Registry. Clin Gastroenterol Hepatol. 2024 Jan 11. Ahuja D, Luo J, Qi Y, Syal G, Boland BS, Chang J, Ma C, Jairath V, Xu R, Singh S. PMID: 38216022.
      View in: PubMed   Mentions:    Fields:    
    5. AGA Clinical Practice Guideline on the Management of Pouchitis and Inflammatory Pouch Disorders. Gastroenterology. 2024 Jan; 166(1):59-85. Barnes EL, Agrawal M, Syal G, Ananthakrishnan AN, Cohen BL, Haydek JP, Al Kazzi ES, Eisenstein S, Hashash JG, Sultan SS, Raffals LE, Singh S, AGA Clinical Guidelines Committee. Electronic address: clinicalpractice@gastro.org. PMID: 38128971.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Comparative Persistence of Non-tumor Necrosis Factor (TNF) vs. TNF Antagonists for Post-operative Prophylaxis in Crohn's Disease (CD). Dig Dis Sci. 2024 Jan; 69(1):235-245. Gu P, Dube S, Lee Y, Yang S, Li D, Haritunians T, Vasiliauskas E, Bonthala N, Syal G, Yarur A, Ziring D, Targan S, Rabizadeh S, Melmed GY, Fleshner P, McGovern DPB. PMID: 38015321; PMCID: PMC10787872.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Patients' Perspectives, Experiences, and Concerns With Perianal Fistulae: Insights From Online Targeted-Disease Forums. Crohns Colitis 360. 2023 Oct; 5(4):otad073. Khalil C, van Deen WK, Dupuy T, Syal G, Arnold C, Cazzetta SE, Nazarey PP, Almario CV, Spiegel BMR. PMID: 38046445; PMCID: PMC10693318.
      View in: PubMed   Mentions:
    8. Effectiveness of Oral Tofacitinib in Chronic Pouchitis: A Prospective, Open-Label Pilot Study. Inflamm Bowel Dis. 2023 Oct 28. Syal G, Mishkin DS, Banty A, Lee S, Fontelera N, Hampton M, Ziring D, Fleshner PR, Melmed GY. PMID: 37898112.
      View in: PubMed   Mentions:    Fields:    
    9. Withdrawal of Immunomodulators or TNF Antagonists in Patients With Inflammatory Bowel Diseases in Remission on Combination Therapy: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2024 01; 22(1):22-33.e6. Katibian DJ, Solitano V, Polk DB, Nguyen T, Ma C, Syal G, Kobayashi T, Hibi T, Buhl S, Ainsworth MA, Jairath V, Singh S. PMID: 37716619.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis. Gut. 2023 11; 72(11):2068-2080. Akhlaghpour M, Haritunians T, More SK, Thomas LS, Stamps DT, Dube S, Li D, Yang S, Landers CJ, Mengesha E, Hamade H, Murali R, Potdar AA, Wolf AJ, Botwin GJ, Khrom M, International IBD Genetics Consortium, Ananthakrishnan AN, Faubion WA, Jabri B, Lira SA, Newberry RD, Sandler RS, Sartor RB, Xavier RJ, Brant SR, Cho JH, Duerr RH, Lazarev MG, Rioux JD, Schumm LP, Silverberg MS, Zaghiyan K, Fleshner P, Melmed GY, Vasiliauskas EA, Ha C, Rabizadeh S, Syal G, Bonthala NN, Ziring DA, Targan SR, Long MD, McGovern DPB, Michelsen KS. PMID: 37080587.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. Azathioprine Withdrawal Is Cost-Effective in Patients with Crohn's Disease in Remission on Infliximab and Azathioprine. Dig Dis Sci. 2023 02; 68(2):404-413. Syal G, Melmed GY, Almario CV, Spiegel BMR. PMID: 36512266.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Comparative Safety and Effectiveness of Biologic Therapy for Crohn's Disease: A CA-IBD Cohort Study. Clin Gastroenterol Hepatol. 2023 08; 21(9):2359-2369.e5. Singh S, Kim J, Luo J, Paul P, Rudrapatna V, Park S, Zheng K, Syal G, Ha C, Fleshner P, McGovern D, Sauk JS, Limketkai B, Dulai PS, Boland BS, Eisenstein S, Ramamoorthy S, Melmed G, Mahadevan U, Sandborn WJ, Ohno-Machado L. PMID: 36343846.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    13. Interactive Inflammatory Bowel Disease Biologics Decision Aid Does Not Improve Patient Outcomes Over Static Education: Results From a Randomized Trial. Am J Gastroenterol. 2022 09 01; 117(9):1508-1518. Almario CV, van Deen WK, Chen M, Gale R, Sidorkiewicz S, Choi SY, Bonthala N, Ha C, Syal G, Dupuy T, Liu X, Melmed GY, Spiegel BMR. PMID: 35973146; PMCID: PMC9450884.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Effect of Obesity on Risk of Hospitalization, Surgery, and Serious Infection in Biologic-Treated Patients With Inflammatory Bowel Diseases: A CA-IBD Cohort Study. Am J Gastroenterol. 2022 10 01; 117(10):1639-1647. Gu P, Luo J, Kim J, Paul P, Limketkai B, Sauk JS, Park S, Parekh N, Zheng K, Rudrapatna V, Syal G, Ha C, McGovern DP, Melmed GY, Fleshner P, Eisenstein S, Ramamoorthy S, Dulai PS, Boland BS, Grunvald E, Mahadevan U, Ohno-Machado L, Sandborn WJ, Singh S. PMID: 35973139.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    15. Effectiveness and Safety of Biologic Therapy in Hispanic Vs Non-Hispanic Patients With Inflammatory Bowel Diseases: A CA-IBD Cohort Study. Clin Gastroenterol Hepatol. 2023 01; 21(1):173-181.e5. Nguyen NH, Luo J, Paul P, Kim J, Syal G, Ha C, Rudrapatna V, Park S, Parekh N, Zheng K, Sauk JS, Limketkai B, Fleshner P, Eisenstein S, Ramamoorthy S, Melmed G, Dulai PS, Boland BS, Mahadevan U, Sandborn WJ, Ohno-Machado L, McGovern D, Singh S. PMID: 35644340; PMCID: PMC9701245.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Magnitude of Preoperative C-Reactive Protein Elevation Is Associated With De Novo Crohn's Disease After Ileal Pouch-Anal Anastomosis in Patients With Severe Colitis. Dis Colon Rectum. 2022 03 01; 65(3):399-405. Takakura WR, Mirocha J, Ovsepyan G, Zaghiyan KN, Syal G, Fleshner P. PMID: 34657077.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Appropriateness of Medical and Surgical Treatments for Chronic Pouchitis Using RAND/UCLA Appropriateness Methodology. Dig Dis Sci. 2022 Oct; 67(10):4687-4694. Syal G, Sparrow MP, Velayos F, Cheifetz AS, Devlin S, Irving PM, Kaplan GG, Raffals LE, Ullman T, Gecse KB, Fleshner PR, Lightner AL, Siegel CA, Melmed GY. PMID: 35006492.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Health Maintenance Consensus for Adults With Inflammatory Bowel Disease. Inflamm Bowel Dis. 2021 10 18; 27(10):1552-1563. Syal G, Serrano M, Jain A, Cohen BL, Rieder F, Stone C, Abraham B, Hudesman D, Malter L, McCabe R, Holubar S, Afzali A, Cheifetz AS, Gaidos JKJ, Moss AC. PMID: 34279600; PMCID: PMC8861367.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Preoperative Serum Vedolizumab Levels Do Not Impact Postoperative Outcomes in Inflammatory Bowel Disease. Dis Colon Rectum. 2021 10 01; 64(10):1259-1266. Parrish AB, Lopez NE, Truong A, Zaghiyan K, Melmed GY, McGovern DPB, Ha C, Syal G, Bonthala N, Jain A, Landers CJ, Targan SR, Fleshner P. PMID: 34516445.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    20. Endoscopic evaluation after surgery in inflammatory bowel disease. Lancet Gastroenterol Hepatol. 2021 09; 6(9):690-691. Syal G, Fleshner PR, Melmed GY. PMID: 34391521.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Decreased Antibody Responses to Ad26.COV2.S Relative to SARS-CoV-2 mRNA Vaccines in Patients With Inflammatory Bowel Disease. Gastroenterology. 2021 12; 161(6):2041-2043.e1. Pozdnyakova V, Botwin GJ, Sobhani K, Prostko J, Braun J, Mcgovern DPB, Melmed GY, Appel K, Banty A, Feldman E, Ha C, Kumar R, Lee S, Rabizadeh S, Stein T, Syal G, Targan S, Vasiliauskas E, Ziring D, Debbas P, Hampton M, Mengesha E, Stewart JL, Frias EC, Cheng S, Ebinger J, Figueiredo JC, Boland B, Charabaty A, Chiorean M, Cohen E, Flynn A, Valentine J, Fudman D, Horizon A, Hou J, Hwang C, Lazarev M, Lum D, Fausel R, Reddy S, Mattar M, Metwally M, Ostrov A, Parekh N, Raffals L, Sheibani S, Siegel C, Wolf D, Younes Z. PMID: 34391771; PMCID: PMC8359492.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    22. Antitumour necrosis factor therapy is associated with de novo Crohn's disease after ileal pouch-anal anastomosis. Colorectal Dis. 2021 Sep; 23(9):2416-2424. Truong A, Zaghiyan KN, Mirocha J, Melmed GY, McGovern DPB, Syal G, Ha CY, Targan SR, Fleshner PR. PMID: 34157179; PMCID: PMC8440372.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Pre-pouch Ileitis is Associated with Development of Crohn's Disease-like Complications and Pouch Failure. J Crohns Colitis. 2021 Jun 22; 15(6):960-968. Syal G, Shemtov R, Bonthala N, Vasiliauskas EA, Feldman EJ, Zaghiyan K, Ha CY, McGovern DPB, Targan SR, Melmed GY, Fleshner PR. PMID: 33300546; PMCID: PMC8218713.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Real-World Effectiveness and Safety of Tofacitinib in Crohn's Disease and IBD-U: A Multicenter Study From the TROPIC Consortium. Clin Gastroenterol Hepatol. 2021 10; 19(10):2207-2209.e3. Fenster M, Alayo QA, Khatiwada A, Wang W, Dimopoulos C, Gutierrez A, Ciorba MA, Christophi GP, Hirten RP, Ha C, Beniwal-Patel P, Cohen BL, Syal G, Yarur A, Patel A, Colombel JF, Pekow J, Ungaro RC, Rubin DT, Deepak P. PMID: 33068786; PMCID: PMC8044250.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    25. Disease and Treatment Patterns Among Patients With Pouch-related Conditions in a Cohort of Large Tertiary Care Inflammatory Bowel Disease Centers in the United States. Crohns Colitis 360. 2020 Jul; 2(3):otaa039. Barnes EL, Raffals L, Long MD, Syal G, Kayal M, Ananthakrishnan A, Cohen B, Pekow J, Deepak P, Colombel JF, Herfarth HH, Sandler RS. PMID: 32744536; PMCID: PMC7380550.
      View in: PubMed   Mentions: 6  
    26. Safety of Tofacitinib in a Real-World Cohort of Patients With Ulcerative Colitis. Clin Gastroenterol Hepatol. 2021 08; 19(8):1592-1601.e3. Deepak P, Alayo QA, Khatiwada A, Lin B, Fenster M, Dimopoulos C, Bader G, Weisshof R, Jacobs M, Gutierrez A, Ciorba MA, Christophi GP, Patel A, Hirten RP, Colombel JF, Rubin DT, Ha C, Beniwal-Patel P, Ungaro RC, Syal G, Pekow J, Cohen BL, Yarur A. PMID: 32629130; PMCID: PMC7779667.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    27. Hypoalbuminemia and Bandemia Predict Failure of Infliximab Rescue Therapy in Acute Severe Ulcerative Colitis. Dig Dis Sci. 2021 01; 66(1):199-205. Syal G, Robbins L, Kashani A, Bonthala N, Feldman E, Fleshner P, Vasiliauskas E, McGovern D, Ha C, Targan S, Melmed GY. PMID: 32170473.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    28. Is It Time For High Dose Influenza Vaccination In Inflammatory Bowel Diseases? Inflamm Bowel Dis. 2020 03 04; 26(4):603-605. Syal G, Melmed GY. PMID: 31504529.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    29. Efficacy of Vedolizumab for Refractory Pouchitis of the Ileo-anal Pouch: Results From a Multicenter US Cohort. Inflamm Bowel Dis. 2019 08 20; 25(9):1569-1576. Gregory M, Weaver KN, Hoversten P, Hicks SB, Patel D, Ciorba MA, Gutierrez AM, Beniwal-Patel P, Palam S, Syal G, Herfarth HH, Christophi G, Raffals L, Barnes EL, Deepak P. PMID: 30810748; PMCID: PMC6939832.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    30. Ustekinumab Is Effective for the Treatment of Crohn's Disease of the Pouch in a Multicenter Cohort. Inflamm Bowel Dis. 2019 03 14; 25(4):767-774. Weaver KN, Gregory M, Syal G, Hoversten P, Hicks SB, Patel D, Christophi G, Beniwal-Patel P, Isaacs KL, Raffals L, Deepak P, Herfarth HH, Barnes EL. PMID: 30295784.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    31. Fecal Microbiota Transplantation in Inflammatory Bowel Disease: A Primer for Internists. Am J Med. 2018 09; 131(9):1017-1024. Syal G, Kashani A, Shih DQ. PMID: 29605414.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    32. Recurrent Obstructive Giant Inflammatory Polyposis of the Colon. ACG Case Rep J. 2016 Aug; 3(4):e89. Syal G, Budhraja V. PMID: 27807551; PMCID: PMC5062662.
      View in: PubMed   Mentions: 3  
    33. Seizures as a Potential Complication of Treatment With Simeprevir and Sofosbuvir. Am J Ther. 2016 Mar-Apr; 23(2):e570-1. Syal G, Heldenbrand SD, Duarte-Rojo A. PMID: 25549078.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. An innovative technique for management of esophageal pill impaction. Gastrointest Endosc. 2015 Aug; 82(2):422-3. Syal G, Klair JS, Dang S. PMID: 26183499.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    35. Rare Synchronous Gastrointestinal Plasmacytomas of Colon and Stomach. ACG Case Rep J. 2015 Jul; 2(4):224-6. Syal G, Sethi S, Dang S, Aduli F. PMID: 26203446; PMCID: PMC4508948.
      View in: PubMed   Mentions: 1  
    36. Leg Swelling and Mildly Deranged Liver Tests: An Unusual Presentation of a Usual Diagnosis. Multiple Simple Liver Cysts. Gastroenterology. 2015 Aug; 149(2):e10-1. Syal G, Klair JS, Aduli F. PMID: 26123555.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    37. MCP-1 downregulates MMP-9 export via vesicular redistribution to lysosomes in rat portal fibroblasts. Physiol Rep. 2014 Nov 01; 2(11). Hickman DA, Syal G, Fausther M, Lavoie EG, Goree JR, Storrie B, Dranoff JA. PMID: 25413315; PMCID: PMC4255798.
      View in: PubMed   Mentions:    Fields:    
    38. Progressive kidney failure as the sole manifestation of extrapulmonary sarcoidosis. J Ark Med Soc. 2013 Sep; 110(4):64-6. Sethi S, Relia N, Syal G, Kaushik C, Gokden N, Malik AB. PMID: 24079056.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    39. Aortic intimal sarcoma masquerading as bilateral renal artery stenosis. J Nephrol. 2013 Sep-Oct; 26(5):941-4. Sethi S, Pothineni NK, Syal G, Ali SM, Krause MW. PMID: 24052470.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    40. Advances in cholangiocyte immunobiology. Am J Physiol Gastrointest Liver Physiol. 2012 Nov 15; 303(10):G1077-86. Syal G, Fausther M, Dranoff JA. PMID: 22961800; PMCID: PMC3517647.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
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