Christopher Steele

Title(s)	Staff Res Assoc , Cellular and Molecular Medicine
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGenerator. BMC Genomics. 2023 Aug 21; 24(1):469. Khandekar A, Vangara R, Barnes M, Díaz-Gay M, Abbasi A, Bergstrom EN, Steele CD, Pillay N, Alexandrov LB. PMID: 37605126; PMCID: PMC10440861.

View in: PubMed Mentions: 2 Fields:
Gen Genetics
Translation:Humans
Mitotic tethering enables inheritance of shattered micronuclear chromosomes. Nature. 2023 Jun; 618(7967):1049-1056. Trivedi P, Steele CD, Au FKC, Alexandrov LB, Cleveland DW. PMID: 37316668; PMCID: PMC10424572.

View in: PubMed Mentions: 9 Fields:
Sci Science
Translation:Humans Cells
Genomic Patterns of Malignant Peripheral Nerve Sheath Tumor (MPNST) Evolution Correlate with Clinical Outcome and Are Detectable in Cell-Free DNA. Cancer Discov. 2023 03 01; 13(3):654-671. Cortes-Ciriano I, Steele CD, Piculell K, Al-Ibraheemi A, Eulo V, Bui MM, Chatzipli A, Dickson BC, Borcherding DC, Feber A, Galor A, Hart J, Jones KB, Jordan JT, Kim RH, Lindsay D, Miller C, Nishida Y, Proszek PZ, Serrano J, Sundby RT, Szymanski JJ, Ullrich NJ, Viskochil D, Wang X, Snuderl M, Park PJ, Flanagan AM, Hirbe AC, Pillay N, Miller DT, Genomics of MPNST (GeM) Consortium. PMID: 36598417; PMCID: PMC9983734.

View in: PubMed Mentions: 11 Fields:
Neo Neoplasms
Translation:Humans Cells
Visualizing and exploring patterns of large mutational events with SigProfilerMatrixGenerator. bioRxiv. 2023 Feb 04. Khandekar A, Vangara R, Barnes M, Díaz-Gay M, Abbasi A, Bergstrom EN, Steele CD, Pillay N, Alexandrov LB. PMID: 36778452; PMCID: PMC9915726.

View in: PubMed Mentions:
Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor. Cell Genom. 2022 Nov 09; 2(11):None. Islam SMA, Díaz-Gay M, Wu Y, Barnes M, Vangara R, Bergstrom EN, He Y, Vella M, Wang J, Teague JW, Clapham P, Moody S, Senkin S, Li YR, Riva L, Zhang T, Gruber AJ, Steele CD, Otlu B, Khandekar A, Abbasi A, Humphreys L, Syulyukina N, Brady SW, Alexandrov BS, Pillay N, Zhang J, Adams DJ, Martincorena I, Wedge DC, Landi MT, Brennan P, Stratton MR, Rozen SG, Alexandrov LB. PMID: 36388765; PMCID: PMC9646490.

View in: PubMed Mentions: 56
Signatures of copy number alterations in human cancer. Nature. 2022 06; 606(7916):984-991. Steele CD, Abbasi A, Islam SMA, Bowes AL, Khandekar A, Haase K, Hames-Fathi S, Ajayi D, Verfaillie A, Dhami P, McLatchie A, Lechner M, Light N, Shlien A, Malkin D, Feber A, Proszek P, Lesluyes T, Mertens F, Flanagan AM, Tarabichi M, Van Loo P, Alexandrov LB, Pillay N. PMID: 35705804; PMCID: PMC9242861.

View in: PubMed Mentions: 80 Fields:
Sci Science
Translation:Humans
An overview of mutational and copy number signatures in human cancer. J Pathol. 2022 07; 257(4):454-465. Steele CD, Pillay N, Alexandrov LB. PMID: 35420163; PMCID: PMC9324981.

View in: PubMed Mentions: 6 Fields:
Pat Pathology
Translation:Humans
Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA. Nature. 2022 02; 602(7897):510-517. Bergstrom EN, Luebeck J, Petljak M, Khandekar A, Barnes M, Zhang T, Steele CD, Pillay N, Landi MT, Bafna V, Mischel PS, Harris RS, Alexandrov LB. PMID: 35140399; PMCID: PMC8850194.

View in: PubMed Mentions: 36 Fields:
Sci Science
Translation:Humans
Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma. Eur J Cancer. 2022 02; 162:221-236. Lechner M, Takahashi Y, Turri-Zanoni M, Liu J, Counsell N, Hermsen M, Kaur RP, Zhao T, Ramanathan M, Schartinger VH, Emanuel O, Helman S, Varghese J, Dudas J, Riechelmann H, Sprung S, Haybaeck J, Howard D, Engel NW, Stewart S, Brooks L, Pickles JC, Jacques TS, Fenton TR, Williams L, Vaz FM, O'Flynn P, Stimpson P, Wang S, Hannan SA, Unadkat S, Hughes J, Dwivedi R, Forde CT, Randhawa P, Gane S, Joseph J, Andrews PJ, Royle G, Franchi A, Maragliano R, Battocchio S, Bewicke-Copley H, Pipinikas C, Webster A, Thirlwell C, Ho D, Teschendorff A, Zhu T, Steele CD, Pillay N, Vanhaesebroeck B, Mohyeldin A, Fernandez-Miranda J, Park KW, Le QT, West RB, Saade R, Manes RP, Omay SB, Vining EM, Judson BL, Yarbrough WG, Sansovini M, Silvia N, Grassi I, Bongiovanni A, Capper D, Schüller U, Thavaraj S, Sandison A, Surda P, Hopkins C, Ferrari M, Mattavelli D, Rampinelli V, Facchetti F, Nicolai P, Bossi P, Henriquez OA, Magliocca K, Solares CA, Wise SK, Llorente JL, Patel ZM, Nayak JV, Hwang PH, Lacy PD, Woods R, O'Neill JP, Jay A, Carnell D, Forster MD, Ishii M, London NR, Bell DM, Gallia GL, Castelnuovo P, Severi S, Lund VJ, Hanna EY. PMID: 34980502; PMCID: PMC9554673.

View in: PubMed Mentions: 8 Fields:
Neo Neoplasms
Translation:Humans
Therapeutic vulnerability to PARP1,2 inhibition in RB1-mutant osteosarcoma. Nat Commun. 2021 12 03; 12(1):7064. Zoumpoulidou G, Alvarez-Mendoza C, Mancusi C, Ahmed RM, Denman M, Steele CD, Tarabichi M, Roy E, Davies LR, Manji J, Cristalli C, Scotlandi K, Pillay N, Strauss SJ, Mittnacht S. PMID: 34862364; PMCID: PMC8642453.

View in: PubMed Mentions: 15 Fields:
Bio Biology Sci Science
Translation:Animals Cells
Whole-genome sequencing of single circulating tumor cells from neuroendocrine neoplasms. Endocr Relat Cancer. 2021 08 11; 28(9):631-644. Childs A, Steele CD, Vesely C, Rizzo FM, Ensell L, Lowe H, Dhami P, Vaikkinen H, Luong TV, Conde L, Herrero J, Caplin M, Toumpanakis C, Thirlwell C, Hartley JA, Pillay N, Meyer T. PMID: 34280125; PMCID: PMC8428071.

View in: PubMed Mentions: 4 Fields:
End Endocrinology Neo Neoplasms
Translation:Humans Cells
Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy. Nat Commun. 2021 01 05; 12(1):117. Lechner M, Schartinger VH, Steele CD, Nei WL, Ooft ML, Schreiber LM, Pipinikas CP, Chung GT, Chan YY, Wu F, To KF, Tsang CM, Pearce W, Morelli D, Philpott M, Masterson L, Nibhani R, Wells G, Bell CG, Koller J, Delecluse S, Yip YL, Liu J, Forde CT, Forster MD, Jay A, Dudás J, Krapp A, Wan S, Uprimny C, Sprung S, Haybaeck J, Fenton TR, Chester K, Thirlwell C, Royle G, Marafioti T, Gupta R, Indrasari SR, Herdini C, Slim MAM, Indrawati I, Sutton L, Fles R, Tan B, Yeong J, Jain A, Han S, Wang H, Loke KSH, He W, Xu R, Jin H, Cheng Z, Howard D, Hwang PH, Le QT, Tay JK, West RB, Tsao SW, Meyer T, Riechelmann H, Oppermann U, Delecluse HJ, Willems SM, Chua MLK, Busson P, Lo KW, Wollmann G, Pillay N, Vanhaesebroeck B, Lund VJ. PMID: 33402692; PMCID: PMC7785735.

View in: PubMed Mentions: 18 Fields:
Bio Biology Sci Science
Translation:Humans Animals Cells
H3K27me3 expression and methylation status in histological variants of malignant peripheral nerve sheath tumours. J Pathol. 2020 10; 252(2):151-164. Lyskjaer I, Lindsay D, Tirabosco R, Steele CD, Lombard P, Strobl AC, Rocha AM, Davies C, Ye H, Bekers E, Ingruber J, Lechner M, Amary F, Pillay N, Flanagan AM. PMID: 32666581; PMCID: PMC8432159.

View in: PubMed Mentions: 8 Fields:
Pat Pathology
Translation:Humans Cells
The genomics of undifferentiated sarcoma of soft tissue: Progress, challenges and opportunities. Semin Cancer Biol. 2020 04; 61:42-55. Steele CD, Pillay N. PMID: 31866474.

View in: PubMed Mentions: 7 Fields:
Neo Neoplasms
Translation:Humans Cells
Undifferentiated pleomorphic sarcomas with PRDM10 fusions have a distinct gene expression profile. J Pathol. 2019 12; 249(4):425-434. Hofvander J, Puls F, Pillay N, Steele CD, Flanagan AM, Magnusson L, Nilsson J, Mertens F. PMID: 31313299.

View in: PubMed Mentions: 11 Fields:
Pat Pathology
Translation:Humans Cells
Undifferentiated Sarcomas Develop through Distinct Evolutionary Pathways. Cancer Cell. 2019 03 18; 35(3):441-456.e8. Steele CD, Tarabichi M, Oukrif D, Webster AP, Ye H, Fittall M, Lombard P, Martincorena I, Tarpey PS, Collord G, Haase K, Strauss SJ, Berisha F, Vaikkinen H, Dhami P, Jansen M, Behjati S, Amary MF, Tirabosco R, Feber A, Campbell PJ, Alexandrov LB, Van Loo P, Flanagan AM, Pillay N. PMID: 30889380; PMCID: PMC6428691.

View in: PubMed Mentions: 49 Fields:
Neo Neoplasms
Translation:Humans Cells
Evaluation of low-template DNA profiles using peak heights. Stat Appl Genet Mol Biol. 2016 10 01; 15(5):431-445. Steele CD, Greenhalgh M, Balding DJ. PMID: 27416618.

View in: PubMed Mentions: 3 Fields:
Gen Genetics Mol Molecular Biology Sta Statistics as Topic
Translation:Humans
Choice of population database for forensic DNA profile analysis. Sci Justice. 2014 Dec; 54(6):487-93. Steele CD, Balding DJ. PMID: 25498938; PMCID: PMC4275602.

View in: PubMed Mentions: 4 Fields:
For Forensic Sciences Jur Jurisprudence
Translation:Humans Cells
Worldwide F(ST) estimates relative to five continental-scale populations. Ann Hum Genet. 2014 Nov; 78(6):468-77. Steele CD, Court DS, Balding DJ. PMID: 26460400; PMCID: PMC4223938.

View in: PubMed Mentions: 12 Fields:
Gen Genetics
Translation:Humans Cells
Verifying likelihoods for low template DNA profiles using multiple replicates. Forensic Sci Int Genet. 2014 Nov; 13:82-9. Steele CD, Greenhalgh M, Balding DJ. PMID: 25082140; PMCID: PMC4234080.

View in: PubMed Mentions: 3 Fields:
For Forensic Sciences Gen Genetics Jur Jurisprudence
Translation:Humans Cells