Toshinori Nakayama

Title(s)Adjunct Professor, Medicine
SchoolHealth Sciences
Address9500 Gilman Drive #0912
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. A long noncoding RNA regulates inflammation resolution by mouse macrophages through fatty acid oxidation activation. Proc Natl Acad Sci U S A. 2020 Jun 08. Nakayama Y, Fujiu K, Yuki R, Oishi Y, Morioka MS, Isagawa T, Matsuda J, Oshima T, Matsubara T, Sugita J, Kudo F, Kaneda A, Endo Y, Nakayama T, Nagai R, Komuro I, Manabe I. PMID: 32513690.
      View in: PubMed   Mentions:    Fields:    
    2. Activated invariant natural killer T cells directly recognize leukemia cells in a CD1d-independent manner. Cancer Sci. 2020 Apr 23. Aoki T, Takami M, Takatani T, Motoyoshi K, Ishii A, Hara A, Toyoda T, Okada R, Hino M, Koyama-Nasu R, Kiuchi M, Hirahara K, Kimura MY, Nakayama T, Shimojo N, Motohashi S. PMID: 32324315.
      View in: PubMed   Mentions: 1     Fields:    
    3. CD103hi Treg cells constrain lung fibrosis induced by CD103lo tissue-resident pathogenic CD4 T cells. Nat Immunol. 2019 11; 20(11):1469-1480. Ichikawa T, Hirahara K, Kokubo K, Kiuchi M, Aoki A, Morimoto Y, Kumagai J, Onodera A, Mato N, Tumes DJ, Goto Y, Hagiwara K, Inagaki Y, Sparwasser T, Tobe K, Nakayama T. PMID: 31591568.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    4. The immunopathology of lung fibrosis: amphiregulin-producing pathogenic memory T helper-2 cells control the airway fibrotic responses by inducing eosinophils to secrete osteopontin. Semin Immunopathol. 2019 05; 41(3):339-348. Hirahara K, Aoki A, Morimoto Y, Kiuchi M, Okano M, Nakayama T. PMID: 30968186.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    5. A new therapeutic target: the CD69-Myl9 system in immune responses. Semin Immunopathol. 2019 05; 41(3):349-358. Kimura MY, Koyama-Nasu R, Yagi R, Nakayama T. PMID: 30953160.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    6. Immune Cell-Epithelial/Mesenchymal Interaction Contributing to Allergic Airway Inflammation Associated Pathology. Front Immunol. 2019; 10:570. Hirahara K, Shinoda K, Morimoto Y, Kiuchi M, Aoki A, Kumagai J, Kokubo K, Nakayama T. PMID: 30972065.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. Ezh2 controls development of natural killer T cells, which cause spontaneous asthma-like pathology. J Allergy Clin Immunol. 2019 08; 144(2):549-560.e10. Tumes D, Hirahara K, Papadopoulos M, Shinoda K, Onodera A, Kumagai J, Yip KH, Pant H, Kokubo K, Kiuchi M, Aoki A, Obata-Ninomiya K, Tokoyoda K, Endo Y, Kimura MY, Nakayama T. PMID: 30851295.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    8. Soluble factors derived from neuroblastoma cell lines suppress dendritic cell differentiation and activation. Cancer Sci. 2019 Mar; 110(3):888-902. Harada K, Ihara F, Takami M, Kamata T, Mise N, Yoshizawa H, Hishiki T, Saito T, Terui K, Nakata M, Komatsu S, Ikeuchi T, Nakayama T, Yoshida H, Motohashi S. PMID: 30629318.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    9. ACC1 determines memory potential of individual CD4+ T cells by regulating de novo fatty acid biosynthesis. Nat Metab. 2019 Feb; 1(2):261-275. Endo Y, Onodera A, Obata-Ninomiya K, Koyama-Nasu R, Asou HK, Ito T, Yamamoto T, Kanno T, Nakajima T, Ishiwata K, Kanuka H, Tumes DJ, Nakayama T. PMID: 32694782.
      View in: PubMed   Mentions:
    10. Epigenetic and Transcriptional Regulation in the Induction, Maintenance, Heterogeneity, and Recall-Response of Effector and Memory Th2 Cells. Front Immunol. 2018; 9:2929. Onodera A, Kokubo K, Nakayama T. PMID: 30619290.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    11. An optimized protocol for the analysis of house dust mite (Dermatophagoides farinae)-induced neutrophil-dominant airway inflammation. J Immunol Methods. 2019 02; 465:53-60. Wada T, Hirahara K, Aoki A, Morimoto Y, Kiuchi M, Kumagai J, Okano M, Kokubo K, Kato M, Fukano C, Ohashi-Doi K, Nakayama T. PMID: 30550743.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    12. Crucial role of CD69 in anti-tumor immunity through regulating the exhaustion of tumor-infiltrating T cells. Int Immunol. 2018 11 14; 30(12):559-567. Mita Y, Kimura MY, Hayashizaki K, Koyama-Nasu R, Ito T, Motohashi S, Okamoto Y, Nakayama T. PMID: 30085193.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    13. A comprehensive understanding of the gut mucosal immune system in allergic inflammation. Allergol Int. 2019 Jan; 68(1):17-25. Tokuhara D, Kurashima Y, Kamioka M, Nakayama T, Ernst P, Kiyono H. PMID: 30366757.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    14. Role of leukotriene B4 12-hydroxydehydrogenase in a-galactosylceramide-pulsed dendritic cell therapy for non-small cell lung cancer. Biochem Biophys Res Commun. 2018 11 17; 506(1):27-32. Tanaka K, Kanesaka Y, Takami M, Suzuki A, Hosokawa H, Onodera A, Kamata T, Nagato K, Nakayama T, Yoshino I, Motohashi S. PMID: 30336981.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    15. DUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells. Nat Commun. 2018 10 12; 9(1):4231. Yamamoto T, Endo Y, Onodera A, Hirahara K, Asou HK, Nakajima T, Kanno T, Ouchi Y, Uematsu S, Nishimasu H, Nureki O, Tumes DJ, Shimojo N, Nakayama T. PMID: 30315197.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    16. CD69 prevents PLZFhi innate precursors from prematurely exiting the thymus and aborting NKT2 cell differentiation. Nat Commun. 2018 09 14; 9(1):3749. Kimura MY, Igi A, Hayashizaki K, Mita Y, Shinzawa M, Kadakia T, Endo Y, Ogawa S, Yagi R, Motohashi S, Singer A, Nakayama T. PMID: 30218105.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    17. Amphiregulin-Producing Pathogenic Memory T Helper 2 Cells Instruct Eosinophils to Secrete Osteopontin and Facilitate Airway Fibrosis. Immunity. 2018 07 17; 49(1):134-150.e6. Morimoto Y, Hirahara K, Kiuchi M, Wada T, Ichikawa T, Kanno T, Okano M, Kokubo K, Onodera A, Sakurai D, Okamoto Y, Nakayama T. PMID: 29958800.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    18. The pathogenicity of IL-33 on steroid-resistant eosinophilic inflammation via the activation of memory-type ST2+ CD4+ T cells. J Leukoc Biol. 2018 11; 104(5):895-901. Hirahara K, Mato N, Hagiwara K, Nakayama T. PMID: 29709067.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    19. Mucosal Mesenchymal Cells: Secondary Barrier and Peripheral Educator for the Gut Immune System. Front Immunol. 2017; 8:1787. Kurashima Y, Yamamoto D, Nelson S, Uematsu S, Ernst PB, Nakayama T, Kiyono H. PMID: 29321781.
      View in: PubMed   Mentions: 2     Fields:    
    20. Anti-tumor immunity via the superoxide-eosinophil axis induced by a lipophilic component of Mycobacterium lipomannan. Int Immunol. 2017 11 01; 29(9):411-421. Ito T, Hirahara K, Onodera A, Koyama-Nasu R, Yano I, Nakayama T. PMID: 29099969.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    21. Introduction to "allergic inflammation". Immunol Rev. 2017 07; 278(1):5-7. Nakayama T. PMID: 28658548.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    22. Crucial role for CD69 in allergic inflammatory responses: CD69-Myl9 system in the pathogenesis of airway inflammation. Immunol Rev. 2017 07; 278(1):87-100. Kimura MY, Hayashizaki K, Tokoyoda K, Takamura S, Motohashi S, Nakayama T. PMID: 28658550.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    23. Epigenetic regulation of T-helper cell differentiation, memory, and plasticity in allergic asthma. Immunol Rev. 2017 07; 278(1):8-19. Tumes DJ, Papadopoulos M, Endo Y, Onodera A, Hirahara K, Nakayama T. PMID: 28658556.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    24. Menin Controls the Memory Th2 Cell Function by Maintaining the Epigenetic Integrity of Th2 Cells. J Immunol. 2017 08 01; 199(3):1153-1162. Onodera A, Kiuchi M, Kokubo K, Kato M, Ogino T, Horiuchi S, Kanai U, Hirahara K, Nakayama T. PMID: 28659357.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    25. Maintenance of pathogenic Th2 cells in allergic disorders. Allergol Int. 2017 Jul; 66(3):369-376. Shinoda K, Hirahara K, Nakayama T. PMID: 28391979.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    26. Fatty acid metabolic reprogramming via mTOR-mediated inductions of PPAR? directs early activation of T cells. Nat Commun. 2016 11 30; 7:13683. Angela M, Endo Y, Asou HK, Yamamoto T, Tumes DJ, Tokuyama H, Yokote K, Nakayama T. PMID: 27901044.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    27. Th2 Cells in Health and Disease. Annu Rev Immunol. 2017 04 26; 35:53-84. Nakayama T, Hirahara K, Onodera A, Endo Y, Hosokawa H, Shinoda K, Tumes DJ, Okamoto Y. PMID: 27912316.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    28. The obesity-related pathology and Th17 cells. Cell Mol Life Sci. 2017 04; 74(7):1231-1245. Endo Y, Yokote K, Nakayama T. PMID: 27757507.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    29. Myosin light chains 9 and 12 are functional ligands for CD69 that regulate airway inflammation. Sci Immunol. 2016 Sep 16; 1(3):eaaf9154. Hayashizaki K, Kimura MY, Tokoyoda K, Hosokawa H, Shinoda K, Hirahara K, Ichikawa T, Onodera A, Hanazawa A, Iwamura C, Kakuta J, Muramoto K, Motohashi S, Tumes DJ, Iinuma T, Yamamoto H, Ikehara Y, Okamoto Y, Nakayama T. PMID: 28783682.
      View in: PubMed   Mentions: 6     Fields:    
    30. Blockade of programmed death-1/programmed death ligand pathway enhances the antitumor immunity of human invariant natural killer T cells. Cancer Immunol Immunother. 2016 12; 65(12):1477-1489. Kamata T, Suzuki A, Mise N, Ihara F, Takami M, Makita Y, Horinaka A, Harada K, Kunii N, Yoshida S, Yoshino I, Nakayama T, Motohashi S. PMID: 27631416.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    31. Bach2-Batf interactions control Th2-type immune response by regulating the IL-4 amplification loop. Nat Commun. 2016 09 01; 7:12596. Kuwahara M, Ise W, Ochi M, Suzuki J, Kometani K, Maruyama S, Izumoto M, Matsumoto A, Takemori N, Takemori A, Shinoda K, Nakayama T, Ohara O, Yasukawa M, Sawasaki T, Kurosaki T, Yamashita M. PMID: 27581382.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    32. Thy1+IL-7+ lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation. Proc Natl Acad Sci U S A. 2016 May 17; 113(20):E2842-51. Shinoda K, Hirahara K, Iinuma T, Ichikawa T, Suzuki AS, Sugaya K, Tumes DJ, Yamamoto H, Hara T, Tani-Ichi S, Ikuta K, Okamoto Y, Nakayama T. PMID: 27140620.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    33. Akt1-mediated Gata3 phosphorylation controls the repression of IFN? in memory-type Th2 cells. Nat Commun. 2016 Apr 07; 7:11289. Hosokawa H, Tanaka T, Endo Y, Kato M, Shinoda K, Suzuki A, Motohashi S, Matsumoto M, Nakayama KI, Nakayama T. PMID: 27053161.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    34. CD4+ T-cell subsets in inflammatory diseases: beyond the Th1/Th2 paradigm. Int Immunol. 2016 Apr; 28(4):163-71. Hirahara K, Nakayama T. PMID: 26874355.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    35. Antibody-dependent cellular cytotoxicity toward neuroblastoma enhanced by activated invariant natural killer T cells. Cancer Sci. 2016 Mar; 107(3):233-41. Mise N, Takami M, Suzuki A, Kamata T, Harada K, Hishiki T, Saito T, Terui K, Mitsunaga T, Nakata M, Ikeuchi T, Nakayama T, Yoshida H, Motohashi S. PMID: 26749374.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    36. Pathogenic Th2 (Tpath2) cells in airway inflammation. Oncotarget. 2015 Oct 20; 6(32):32303-4. Endo Y, Nakayama T. PMID: 26459386.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    37. Spatial Interplay between Polycomb and Trithorax Complexes Controls Transcriptional Activity in T Lymphocytes. Mol Cell Biol. 2015 Nov; 35(22):3841-53. Onodera A, Tumes DJ, Watanabe Y, Hirahara K, Kaneda A, Sugiyama F, Suzuki Y, Nakayama T. PMID: 26324324.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    38. Obesity Drives Th17 Cell Differentiation by Inducing the Lipid Metabolic Kinase, ACC1. Cell Rep. 2015 Aug 11; 12(6):1042-55. Endo Y, Asou HK, Matsugae N, Hirahara K, Shinoda K, Tumes DJ, Tokuyama H, Yokote K, Nakayama T. PMID: 26235623.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    39. Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity. Immunity. 2015 May 19; 42(5):877-89. Hirahara K, Onodera A, Villarino AV, Bonelli M, Sciumè G, Laurence A, Sun HW, Brooks SR, Vahedi G, Shih HY, Gutierrez-Cruz G, Iwata S, Suzuki R, Mikami Y, Okamoto Y, Nakayama T, Holland SM, Hunter CA, Kanno Y, O'Shea JJ. PMID: 25992861.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    40. Epigenetics of T cells regulated by Polycomb/Trithorax molecules. Trends Mol Med. 2015 May; 21(5):330-40. Onodera A, Nakayama T. PMID: 25842254.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    41. The interleukin-33-p38 kinase axis confers memory T helper 2 cell pathogenicity in the airway. Immunity. 2015 Feb 17; 42(2):294-308. Endo Y, Hirahara K, Iinuma T, Shinoda K, Tumes DJ, Asou HK, Matsugae N, Obata-Ninomiya K, Yamamoto H, Motohashi S, Oboki K, Nakae S, Saito H, Okamoto Y, Nakayama T. PMID: 25692703.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    42. Matrix metalloproteinase 12 is produced by M2 macrophages and plays important roles in the development of contact hypersensitivity. J Allergy Clin Immunol. 2015 May; 135(5):1397-400. Nakagomi D, Suzuki K, Meguro K, Hosokawa J, Tamachi T, Takatori H, Suto A, Matsue H, Ohara O, Nakayama T, Shimada S, Nakajima H. PMID: 25542885.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    43. Histone acetylation mediated by Brd1 is crucial for Cd8 gene activation during early thymocyte development. Nat Commun. 2014 Dec 18; 5:5872. Mishima Y, Wang C, Miyagi S, Saraya A, Hosokawa H, Mochizuki-Kashio M, Nakajima-Takagi Y, Koide S, Negishi M, Sashida G, Naito T, Ishikura T, Onodera A, Nakayama T, Tenen DG, Yamaguchi N, Koseki H, Taniuchi I, Iwama A. PMID: 25519988.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    44. Sox5 and c-Maf cooperatively induce Th17 cell differentiation via ROR?t induction as downstream targets of Stat3. J Exp Med. 2014 Aug 25; 211(9):1857-74. Tanaka S, Suto A, Iwamoto T, Kashiwakuma D, Kagami S, Suzuki K, Takatori H, Tamachi T, Hirose K, Onodera A, Suzuki J, Ohara O, Yamashita M, Nakayama T, Nakajima H. PMID: 25073789.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    45. The Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis. Nat Commun. 2014 Apr 02; 5:3555. Kuwahara M, Suzuki J, Tofukuji S, Yamada T, Kanoh M, Matsumoto A, Maruyama S, Kometani K, Kurosaki T, Ohara O, Nakayama T, Yamashita M. PMID: 24694524.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    46. Leucomycin A3, a 16-membered macrolide antibiotic, inhibits influenza A virus infection and disease progression. J Antibiot (Tokyo). 2014 Mar; 67(3):213-22. Sugamata R, Sugawara A, Nagao T, Suzuki K, Hirose T, Yamamoto K, Oshima M, Kobayashi K, Sunazuka T, Akagawa KS, Omura S, Nakayama T, Suzuki K. PMID: 24496145.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    47. Pathogenic memory type Th2 cells in allergic inflammation. Trends Immunol. 2014 Feb; 35(2):69-78. Endo Y, Hirahara K, Yagi R, Tumes DJ, Nakayama T. PMID: 24332592.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    48. A novel autoantibody against moesin in the serum of patients with MPO-ANCA-associated vasculitis. Nephrol Dial Transplant. 2014 Jun; 29(6):1168-77. Suzuki K, Nagao T, Itabashi M, Hamano Y, Sugamata R, Yamazaki Y, Yumura W, Tsukita S, Wang PC, Nakayama T, Suzuki K. PMID: 24319012.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    49. Effect of invariant natural killer T cells with IL-5 and activated IL-6 receptor in ventilator-associated lung injury in mice. Exp Lung Res. 2014 Feb; 40(1):1-11. Shiga Y, Sugamata R, Iwamura C, Nagao T, Zao J, Kawakami K, Kawachi S, Nakayama T, Suzuki K. PMID: 24246030.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    50. The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells. Immunity. 2013 Nov 14; 39(5):819-32. Tumes DJ, Onodera A, Suzuki A, Shinoda K, Endo Y, Iwamura C, Hosokawa H, Koseki H, Tokoyoda K, Suzuki Y, Motohashi S, Nakayama T. PMID: 24238339.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    51. Gata3/Ruvbl2 complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression. Proc Natl Acad Sci U S A. 2013 Nov 12; 110(46):18626-31. Hosokawa H, Tanaka T, Kato M, Shinoda K, Tohyama H, Hanazawa A, Tamaki Y, Hirahara K, Yagi R, Sakikawa I, Morita A, Nagira M, Poyurovsky MV, Suzuki Y, Motohashi S, Nakayama T. PMID: 24167278.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    52. CD49b-dependent establishment of T helper cell memory. Immunol Cell Biol. 2013 Sep; 91(8):524-31. Hanazawa A, Hayashizaki K, Shinoda K, Yagita H, Okumura K, Löhning M, Hara T, Tani-ichi S, Ikuta K, Eckes B, Radbruch A, Tokoyoda K, Nakayama T. PMID: 23897120.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    53. Genome-Wide Gene Expression Profiling Revealed a Critical Role for GATA3 in the Maintenance of the Th2 Cell Identity. PLoS One. 2013; 8(6):e66468. Sasaki T, Onodera A, Hosokawa H, Watanabe Y, Horiuchi S, Yamashita J, Tanaka H, Ogawa Y, Suzuki Y, Nakayama T. PMID: 23824597.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    54. Paraoxonase-1 suppresses experimental colitis via the inhibition of IFN-? production from CD4 T cells. J Immunol. 2013 Jul 15; 191(2):949-60. Yamashita J, Iwamura C, Ito T, Narita M, Hara Y, Sasaki T, Masuda D, Takahashi M, Tsuchiya M, Hada K, Ishikawa M, Matsuo T, Ohno Y, Tanaka H, Maruyama H, Ogawa Y, Nakayama T. PMID: 23772025.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    55. Crucial role for CD69 in the pathogenesis of dextran sulphate sodium-induced colitis. PLoS One. 2013; 8(6):e65494. Hasegawa A, Iwamura C, Kitajima M, Hashimoto K, Otsuyama K, Ogino H, Nakayama T, Shirai M. PMID: 23785429.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    56. Interleukin-25 induces pulmonary arterial remodeling via natural killer T cell-dependent mechanisms. Int Arch Allergy Immunol. 2013; 161 Suppl 2:118-24. Kawashima S, Hirose K, Takahashi K, Tamachi T, Ikeda K, Tokoyoda K, Nakayama T, Nakajima H. PMID: 23711862.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    57. Functionally distinct Gata3/Chd4 complexes coordinately establish T helper 2 (Th2) cell identity. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):4691-6. Hosokawa H, Tanaka T, Suzuki Y, Iwamura C, Ohkubo S, Endoh K, Kato M, Endo Y, Onodera A, Tumes DJ, Kanai A, Sugano S, Nakayama T. PMID: 23471993.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    58. Transcriptional reprogramming of mature CD4? helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes. Nat Immunol. 2013 Mar; 14(3):281-9. Mucida D, Husain MM, Muroi S, van Wijk F, Shinnakasu R, Naoe Y, Reis BS, Huang Y, Lambolez F, Docherty M, Attinger A, Shui JW, Kim G, Lena CJ, Sakaguchi S, Miyamoto C, Wang P, Atarashi K, Park Y, Nakayama T, Honda K, Ellmeier W, Kronenberg M, Taniuchi I, Cheroutre H. PMID: 23334788.
      View in: PubMed   Mentions: 96     Fields:    Translation:AnimalsCells
    59. Regulation of memory CD4 T-cell pool size and function by natural killer T cells in vivo. Proc Natl Acad Sci U S A. 2012 Oct 16; 109(42):16992-7. Iwamura C, Shinoda K, Endo Y, Watanabe Y, Tumes DJ, Motohashi S, Kawahara K, Kinjo Y, Nakayama T. PMID: 23027937.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    60. The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-ß and suppresses T(H)2 differentiation. Nat Immunol. 2012 Jul 01; 13(8):778-86. Kuwahara M, Yamashita M, Shinoda K, Tofukuji S, Onodera A, Shinnakasu R, Motohashi S, Hosokawa H, Tumes D, Iwamura C, Lefebvre V, Nakayama T. PMID: 22751141.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    61. AP-1 is involved in ICOS gene expression downstream of TCR/CD28 and cytokine receptor signaling. Eur J Immunol. 2012 Jul; 42(7):1850-62. Watanabe M, Nakajima S, Ohnuki K, Ogawa S, Yamashita M, Nakayama T, Murakami Y, Tanabe K, Abe R. PMID: 22585681.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    62. Accumulation of activated invariant natural killer T cells in the tumor microenvironment after a-galactosylceramide-pulsed antigen presenting cells. J Clin Immunol. 2012 Oct; 32(5):1071-81. Nagato K, Motohashi S, Ishibashi F, Okita K, Yamasaki K, Moriya Y, Hoshino H, Yoshida S, Hanaoka H, Fujii S, Taniguchi M, Yoshino I, Nakayama T. PMID: 22534863.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    63. Identification of a new pathway for Th1 cell development induced by cooperative stimulation with IL-4 and TGF-ß. J Immunol. 2012 May 15; 188(10):4846-57. Tofukuji S, Kuwahara M, Suzuki J, Ohara O, Nakayama T, Yamashita M. PMID: 22504655.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    64. Type II membrane protein CD69 regulates the formation of resting T-helper memory. Proc Natl Acad Sci U S A. 2012 May 08; 109(19):7409-14. Shinoda K, Tokoyoda K, Hanazawa A, Hayashizaki K, Zehentmeier S, Hosokawa H, Iwamura C, Koseki H, Tumes DJ, Radbruch A, Nakayama T. PMID: 22474373.
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    65. A possible relationship of natural killer T cells with humoral immune response to 23-valent pneumococcal polysaccharide vaccine in clinical settings. Vaccine. 2012 May 09; 30(22):3304-10. Miyasaka T, Aoyagi T, Uchiyama B, Oishi K, Nakayama T, Kinjo Y, Miyazaki Y, Kunishima H, Hirakata Y, Kaku M, Kawakami K. PMID: 22426326.
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    66. Murine Schnurri-2 controls natural killer cell function and lymphoma development. Leuk Lymphoma. 2012 Mar; 53(3):479-86. Yamashita J, Iwamura C, Mitsumori K, Hosokawa H, Sasaki T, Takahashi M, Tanaka H, Kaneko K, Hanazawa A, Watanabe Y, Shinoda K, Tumes D, Motohashi S, Nakayama T. PMID: 21936769.
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    67. Eomesodermin controls interleukin-5 production in memory T helper 2 cells through inhibition of activity of the transcription factor GATA3. Immunity. 2011 Nov 23; 35(5):733-45. Endo Y, Iwamura C, Kuwahara M, Suzuki A, Sugaya K, Tumes DJ, Tokoyoda K, Hosokawa H, Yamashita M, Nakayama T. PMID: 22118525.
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    68. Nasal submucosal administration of antigen-presenting cells induces effective immunological responses in cancer immunotherapy. Adv Otorhinolaryngol. 2011; 72:149-52. Okamoto Y, Fujikawa A, Kurosaki M, Yamasaki K, Sakurai D, Horiguchi S, Nakayama T. PMID: 21865716.
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    69. Memory type 2 helper T cells induce long-lasting antitumor immunity by activating natural killer cells. Cancer Res. 2011 Jul 15; 71(14):4790-8. Kitajima M, Ito T, Tumes DJ, Endo Y, Onodera A, Hashimoto K, Motohashi S, Yamashita M, Nishimura T, Ziegler SF, Nakayama T. PMID: 21646476.
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    70. HIV-1 Nef impairs multiple T-cell functions in antigen-specific immune response in mice. Int Immunol. 2011 Jul; 23(7):433-41. Fujii H, Ato M, Takahashi Y, Otake K, Hashimoto S, Kaji T, Tsunetsugu-Yokota Y, Fujita M, Adachi A, Nakayama T, Taniguchi M, Koyasu S, Takemori T. PMID: 21642447.
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    71. Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA3. J Immunol. 2011 Jun 01; 186(11):6378-89. Horiuchi S, Onodera A, Hosokawa H, Watanabe Y, Tanaka T, Sugano S, Suzuki Y, Nakayama T. PMID: 21536806.
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    72. Repressor of GATA negatively regulates murine contact hypersensitivity through the inhibition of type-2 allergic responses. Clin Immunol. 2011 Jun; 139(3):267-76. Hirasaki Y, Iwamura C, Yamashita M, Ito T, Kitajima M, Shinoda K, Namiki T, Terasawa K, Nakayama T. PMID: 21398189.
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    73. Direct activation of glomerular endothelial cells by anti-moesin activity of anti-myeloperoxidase antibody. Nephrol Dial Transplant. 2011 Sep; 26(9):2752-60. Nagao T, Suzuki K, Utsunomiya K, Matsumura M, Saiga K, Wang PC, Minamitani H, Aratani Y, Nakayama T, Suzuki K. PMID: 21378392.
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    74. Apolipoprotein A-II suppressed concanavalin A-induced hepatitis via the inhibition of CD4 T cell function. J Immunol. 2011 Mar 15; 186(6):3410-20. Yamashita J, Iwamura C, Sasaki T, Mitsumori K, Ohshima K, Hada K, Hara N, Takahashi M, Kaneshiro Y, Tanaka H, Kaneko K, Nakayama T. PMID: 21300819.
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    75. Anti-tumor immune responses induced by iNKT cell-based immunotherapy for lung cancer and head and neck cancer. Clin Immunol. 2011 Aug; 140(2):167-76. Motohashi S, Okamoto Y, Yoshino I, Nakayama T. PMID: 21349771.
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    76. Role of NKT cells in allergic asthma. Curr Opin Immunol. 2010 Dec; 22(6):807-13. Iwamura C, Nakayama T. PMID: 21115332.
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    77. A set of genes associated with the interferon-? response of lung cancer patients undergoing a-galactosylceramide-pulsed dendritic cell therapy. Cancer Sci. 2010 Nov; 101(11):2333-40. Okita K, Motohashi S, Shinnakasu R, Nagato K, Yamasaki K, Sato Y, Kitamura H, Hijikata A, Yamashita M, Shimizu K, Fujii S, Ohara O, Taniguchi M, Sakaida I, Nakayama T. PMID: 20804502.
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    78. STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells. J Exp Med. 2010 Oct 25; 207(11):2493-506. Onodera A, Yamashita M, Endo Y, Kuwahara M, Tofukuji S, Hosokawa H, Kanai A, Suzuki Y, Nakayama T. PMID: 20956546.
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    79. Essential role of endogenous heat shock protein 90 of dendritic cells in antigen cross-presentation. J Immunol. 2010 Sep 01; 185(5):2693-700. Ichiyanagi T, Imai T, Kajiwara C, Mizukami S, Nakai A, Nakayama T, Udono H. PMID: 20668218.
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    80. The TCR-mediated signaling pathways that control the direction of helper T cell differentiation. Semin Immunol. 2010 Oct; 22(5):303-9. Nakayama T, Yamashita M. PMID: 20488727.
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    81. Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7461-6. Suzuki S, Tanaka T, Poyurovsky MV, Nagano H, Mayama T, Ohkubo S, Lokshin M, Hosokawa H, Nakayama T, Suzuki Y, Sugano S, Sato E, Nagao T, Yokote K, Tatsuno I, Prives C. PMID: 20351271.
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    82. Polycomb group gene product Ring1B regulates Th2-driven airway inflammation through the inhibition of Bim-mediated apoptosis of effector Th2 cells in the lung. J Immunol. 2010 Apr 15; 184(8):4510-20. Suzuki A, Iwamura C, Shinoda K, Tumes DJ, Kimura MY, Hosokawa H, Endo Y, Horiuchi S, Tokoyoda K, Koseki H, Yamashita M, Nakayama T. PMID: 20237291.
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    83. Color-coded real-time cellular imaging of lung T-lymphocyte accumulation and focus formation in a mouse asthma model. J Allergy Clin Immunol. 2010 Feb; 125(2):461-468.e6. Hasegawa A, Hayashi K, Kishimoto H, Yang M, Tofukuji S, Suzuki K, Nakajima H, Hoffman RM, Shirai M, Nakayama T. PMID: 20031194.
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    84. Memory Th1/Th2 cell generation controlled by Schnurri-2. Adv Exp Med Biol. 2010; 684:1-10. Nakayama T, Kimura MY. PMID: 20795536.
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    85. Naringenin chalcone suppresses allergic asthma by inhibiting the type-2 function of CD4 T cells. Allergol Int. 2010 Mar; 59(1):67-73. Iwamura C, Shinoda K, Yoshimura M, Watanabe Y, Obata A, Nakayama T. PMID: 20035147.
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    86. CD69 controls the pathogenesis of allergic airway inflammation. J Immunol. 2009 Dec 15; 183(12):8203-15. Miki-Hosokawa T, Hasegawa A, Iwamura C, Shinoda K, Tofukuji S, Watanabe Y, Hosokawa H, Motohashi S, Hashimoto K, Shirai M, Yamashita M, Nakayama T. PMID: 19923457.
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    87. The Runx3 transcription factor augments Th1 and down-modulates Th2 phenotypes by interacting with and attenuating GATA3. J Immunol. 2009 Dec 15; 183(12):7817-24. Kohu K, Ohmori H, Wong WF, Onda D, Wakoh T, Kon S, Yamashita M, Nakayama T, Kubo M, Satake M. PMID: 19933870.
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    88. Protective roles of B and T lymphocyte attenuator in NKT cell-mediated experimental hepatitis. J Immunol. 2010 Jan 01; 184(1):127-33. Iwata A, Watanabe N, Oya Y, Owada T, Ikeda K, Suto A, Kagami S, Hirose K, Kanari H, Kawashima S, Nakayama T, Taniguchi M, Iwamoto I, Nakajima H. PMID: 19949073.
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    89. Adjuvant activity mediated by iNKT cells. Semin Immunol. 2010 Apr; 22(2):97-102. Fujii S, Motohashi S, Shimizu K, Nakayama T, Yoshiga Y, Taniguchi M. PMID: 19939703.
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    90. Enhanced Th2 cell differentiation and allergen-induced airway inflammation in Zfp35-deficient mice. J Immunol. 2009 Oct 15; 183(8):5388-96. Kitajima M, Iwamura C, Miki-Hosokawa T, Shinoda K, Endo Y, Watanabe Y, Shinnakasu R, Hosokawa H, Hashimoto K, Motohashi S, Koseki H, Ohara O, Yamashita M, Nakayama T. PMID: 19783676.
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    91. Natural killer T cell-mediated immunotherapy for malignant diseases. Front Biosci (Schol Ed). 2009 Jun 01; 1:108-16. Motohashi S, Nakayama T. PMID: 19482686.
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    92. Immune response induced by fluorescent nanocrystal quantum dots in vitro and in vivo. IEEE Trans Nanobioscience. 2009 Mar; 8(1):51-7. Hoshino A, Hanada S, Manabe N, Nakayama T, Yamamoto K. PMID: 19304501.
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    93. Critical role of the Polycomb and Trithorax complexes in the maintenance of CD4 T cell memory. Semin Immunol. 2009 Apr; 21(2):78-83. Nakayama T, Yamashita M. PMID: 19269851.
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    94. A phase I-II study of alpha-galactosylceramide-pulsed IL-2/GM-CSF-cultured peripheral blood mononuclear cells in patients with advanced and recurrent non-small cell lung cancer. J Immunol. 2009 Feb 15; 182(4):2492-501. Motohashi S, Nagato K, Kunii N, Yamamoto H, Yamasaki K, Okita K, Hanaoka H, Shimizu N, Suzuki M, Yoshino I, Taniguchi M, Fujisawa T, Nakayama T. PMID: 19201905.
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    95. Invariant natural killer T cell-based immunotherapy for cancer. Immunotherapy. 2009 Jan; 1(1):73-82. Motohashi S, Nakayama T. PMID: 20635975.
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    96. A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity. J Exp Med. 2008 Nov 24; 205(12):2727-33. Terashima A, Watarai H, Inoue S, Sekine E, Nakagawa R, Hase K, Iwamura C, Nakajima H, Nakayama T, Taniguchi M. PMID: 19015310.
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    97. Gfi1-mediated stabilization of GATA3 protein is required for Th2 cell differentiation. J Biol Chem. 2008 Oct 17; 283(42):28216-25. Shinnakasu R, Yamashita M, Kuwahara M, Hosokawa H, Hasegawa A, Motohashi S, Nakayama T. PMID: 18701459.
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    98. MPO-ANCA induces IL-17 production by activated neutrophils in vitro via classical complement pathway-dependent manner. J Autoimmun. 2008 Aug; 31(1):79-89. Hoshino A, Nagao T, Nagi-Miura N, Ohno N, Yasuhara M, Yamamoto K, Nakayama T, Suzuki K. PMID: 18501296.
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    99. Repressor of GATA regulates TH2-driven allergic airway inflammation and airway hyperresponsiveness. J Allergy Clin Immunol. 2008 Sep; 122(3):512-20.e11. Hirahara K, Yamashita M, Iwamura C, Shinoda K, Hasegawa A, Yoshizawa H, Koseki H, Gejyo F, Nakayama T. PMID: 18620745.
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    100. Initiation and maintenance of Th2 cell identity. Curr Opin Immunol. 2008 Jun; 20(3):265-71. Nakayama T, Yamashita M. PMID: 18502111.
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    101. Human Th1 differentiation induced by lipoarabinomannan/lipomannan from Mycobacterium bovis BCG Tokyo-172. Int Immunol. 2008 Jul; 20(7):849-60. Ito T, Hasegawa A, Hosokawa H, Yamashita M, Motohashi S, Naka T, Okamoto Y, Fujita Y, Ishii Y, Taniguchi M, Yano I, Nakayama T. PMID: 18469327.
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    102. Lymphoid enhancer factor interacts with GATA-3 and controls its function in T helper type 2 cells. Immunology. 2008 Nov; 125(3):377-86. Hossain MB, Hosokawa H, Hasegawa A, Watarai H, Taniguchi M, Yamashita M, Nakayama T. PMID: 18445004.
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    103. Bmi1 regulates memory CD4 T cell survival via repression of the Noxa gene. J Exp Med. 2008 May 12; 205(5):1109-20. Yamashita M, Kuwahara M, Suzuki A, Hirahara K, Shinnaksu R, Hosokawa H, Hasegawa A, Motohashi S, Iwama A, Nakayama T. PMID: 18411339.
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    104. Progress in allergy signal research on mast cells: regulation of allergic airway inflammation through toll-like receptor 4-mediated modification of mast cell function. J Pharmacol Sci. 2008 Mar; 106(3):332-5. Yamashita M, Nakayama T. PMID: 18360088.
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    105. Toll-like receptors in the respiratory system: their roles in inflammation. Curr Allergy Asthma Rep. 2008 Mar; 8(1):7-13. Iwamura C, Nakayama T. PMID: 18377768.
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    106. Clinical applications of natural killer T cell-based immunotherapy for cancer. Cancer Sci. 2008 Apr; 99(4):638-45. Motohashi S, Nakayama T. PMID: 18294290.
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    107. Survival of skin allografts is prolonged in mice with a dominant-negative H-Ras. Transpl Immunol. 2008 Feb; 18(4):302-6. Funeshima-Fuji N, Fujino M, Kimura H, Takahara S, Nakayama T, Ezaki T, Li XK. PMID: 18158115.
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    108. T cell lineage determination precedes the initiation of TCR beta gene rearrangement. J Immunol. 2007 Sep 15; 179(6):3699-706. Masuda K, Kakugawa K, Nakayama T, Minato N, Katsura Y, Kawamoto H. PMID: 17785806.
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    109. Phase I study of alpha-galactosylceramide-pulsed antigen presenting cells administration to the nasal submucosa in unresectable or recurrent head and neck cancer. Cancer Immunol Immunother. 2008 Mar; 57(3):337-45. Uchida T, Horiguchi S, Tanaka Y, Yamamoto H, Kunii N, Motohashi S, Taniguchi M, Nakayama T, Okamoto Y. PMID: 17690880.
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    110. Schnurri-2 regulates Th2-dependent airway inflammation and airway hyperresponsiveness. Int Immunol. 2007 Jun; 19(6):755-62. Iwamura C, Kimura MY, Shinoda K, Endo Y, Hasegawa A, Yamashita M, Nakayama T. PMID: 17493960.
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    111. Schnurri-2 controls memory Th1 and Th2 cell numbers in vivo. J Immunol. 2007 Apr 15; 178(8):4926-36. Kimura MY, Iwamura C, Suzuki A, Miki T, Hasegawa A, Sugaya K, Yamashita M, Ishii S, Nakayama T. PMID: 17404274.
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    112. Role of alpha-galactosylceramide-activated Valpha14 natural killer T cells in the regulation of allergic diseases. Allergol Int. 2007 Mar; 56(1):1-6. Iwamura C, Nakayama T. PMID: 17259803.
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    113. Immune mechanisms of allergic airway disease: regulation by transcription factors. Crit Rev Immunol. 2007; 27(6):539-46. Yamashita M, Onodera A, Nakayama T. PMID: 18197799.
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    114. IL-21-induced Bepsilon cell apoptosis mediated by natural killer T cells suppresses IgE responses. J Exp Med. 2006 Dec 25; 203(13):2929-37. Harada M, Magara-Koyanagi K, Watarai H, Nagata Y, Ishii Y, Kojo S, Horiguchi S, Okamoto Y, Nakayama T, Suzuki N, Yeh WC, Akira S, Kitamura H, Ohara O, Seino K, Taniguchi M. PMID: 17178921.
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    115. Chromatin remodeling at the Th2 cytokine gene loci in human type 2 helper T cells. Mol Immunol. 2007 Mar; 44(9):2249-56. Kaneko T, Hosokawa H, Yamashita M, Wang CR, Hasegawa A, Kimura MY, Kitajiama M, Kimura F, Miyazaki M, Nakayama T. PMID: 17166591.
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    116. Regulation of Th2 cell development by Polycomb group gene bmi-1 through the stabilization of GATA3. J Immunol. 2006 Dec 01; 177(11):7656-64. Hosokawa H, Kimura MY, Shinnakasu R, Suzuki A, Miki T, Koseki H, van Lohuizen M, Yamashita M, Nakayama T. PMID: 17114435.
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    117. Critical YxKxHxxxRP motif in the C-terminal region of GATA3 for its DNA binding and function. J Immunol. 2006 Nov 01; 177(9):5801-10. Shinnakasu R, Yamashita M, Shinoda K, Endo Y, Hosokawa H, Hasegawa A, Ikemizu S, Nakayama T. PMID: 17056504.
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    118. A phase I study of in vitro expanded natural killer T cells in patients with advanced and recurrent non-small cell lung cancer. Clin Cancer Res. 2006 Oct 15; 12(20 Pt 1):6079-86. Motohashi S, Ishikawa A, Ishikawa E, Otsuji M, Iizasa T, Hanaoka H, Shimizu N, Horiguchi S, Okamoto Y, Fujii S, Taniguchi M, Fujisawa T, Nakayama T. PMID: 17028247.
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    119. Hyperresponsive TH2 cells with enhanced nuclear factor-kappa B activation induce atopic dermatitis-like skin lesions in Nishiki-nezumi Cinnamon/Nagoya mice. J Allergy Clin Immunol. 2006 Sep; 118(3):725-33. Tenda Y, Yamashita M, Kimura MY, Hasegawa A, Shimizu C, Kitajima M, Onodera A, Suzuki A, Seki N, Nakayama T. PMID: 16950294.
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    120. Natural killer T cell-mediated antitumor immune responses and their clinical applications. Cancer Sci. 2006 Sep; 97(9):807-12. Seino K, Motohashi S, Fujisawa T, Nakayama T, Taniguchi M. PMID: 16805854.
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    121. Crucial role of MLL for the maintenance of memory T helper type 2 cell responses. Immunity. 2006 May; 24(5):611-22. Yamashita M, Hirahara K, Shinnakasu R, Hosokawa H, Norikane S, Kimura MY, Hasegawa A, Nakayama T. PMID: 16713978.
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    122. Impaired GATA3-dependent chromatin remodeling and Th2 cell differentiation leading to attenuated allergic airway inflammation in aging mice. J Immunol. 2006 Feb 15; 176(4):2546-54. Hasegawa A, Miki T, Hosokawa H, Hossain MB, Shimizu C, Hashimoto K, Kimura MY, Yamashita M, Nakayama T. PMID: 16456016.
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    123. Regulation of allergic airway inflammation through Toll-like receptor 4-mediated modification of mast cell function. Proc Natl Acad Sci U S A. 2006 Feb 14; 103(7):2286-91. Nigo YI, Yamashita M, Hirahara K, Shinnakasu R, Inami M, Kimura M, Hasegawa A, Kohno Y, Nakayama T. PMID: 16461458.
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    124. Regulation of Toll-like receptor 4 expression in mouse colon by macrophage migration inhibitory factor. Histochem Cell Biol. 2006 May; 125(5):575-82. Ohkawara T, Takeda H, Miyashita K, Nishiwaki M, Nakayama T, Taniguchi M, Yoshiki T, Tanaka J, Takana J, Imamura M, Sugiyama T, Asaka M, Nishihira J. PMID: 16283355.
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    125. Plasma membrane-focused proteomics: dramatic changes in surface expression during the maturation of human dendritic cells. Proteomics. 2005 Oct; 5(15):4001-11. Watarai H, Hinohara A, Nagafune J, Nakayama T, Taniguchi M, Yamaguchi Y. PMID: 16152658.
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    126. Induction of regulatory properties in dendritic cells by Valpha14 NKT cells. J Immunol. 2005 Sep 15; 175(6):3648-55. Kojo S, Seino K, Harada M, Watarai H, Wakao H, Uchida T, Nakayama T, Taniguchi M. PMID: 16148109.
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    127. Ras-ERK MAPK cascade regulates GATA3 stability and Th2 differentiation through ubiquitin-proteasome pathway. J Biol Chem. 2005 Aug 19; 280(33):29409-19. Yamashita M, Shinnakasu R, Asou H, Kimura M, Hasegawa A, Hashimoto K, Hatano N, Ogata M, Nakayama T. PMID: 15975924.
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    128. A phase I study of alpha-galactosylceramide (KRN7000)-pulsed dendritic cells in patients with advanced and recurrent non-small cell lung cancer. Clin Cancer Res. 2005 Mar 01; 11(5):1910-7. Ishikawa A, Motohashi S, Ishikawa E, Fuchida H, Higashino K, Otsuji M, Iizasa T, Nakayama T, Taniguchi M, Fujisawa T. PMID: 15756017.
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    129. Regulation of T helper type 2 cell differentiation by murine Schnurri-2. J Exp Med. 2005 Feb 07; 201(3):397-408. Kimura MY, Hosokawa H, Yamashita M, Hasegawa A, Iwamura C, Watarai H, Taniguchi M, Takagi T, Ishii S, Nakayama T. PMID: 15699073.
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    130. Valpha14 NKT cell-mediated anti-tumor responses and their clinical application. Springer Semin Immunopathol. 2005 Jun; 27(1):65-74. Seino K, Fujii S, Harada M, Motohashi S, Nakayama T, Fujisawa T, Taniguchi M. PMID: 15650847.
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    131. Differentiation of NK1 and NK2 cells. Crit Rev Immunol. 2005; 25(5):361-74. Kimura MY, Nakayama T. PMID: 16167886.
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    132. Hyporesponsiveness of CD4 T cells induced in oral tolerance is maintained by selective impairment in the TCR-induced calcium/NFAT signaling pathway resulting from caspase activation. Ann N Y Acad Sci. 2004 Dec; 1029:344-5. Hachimura S, Kaji T, Asai K, Ise W, Nakayama T, Kaminogawa S. PMID: 15681776.
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    133. STAT6-dependent differentiation and production of IL-5 and IL-13 in murine NK2 cells. J Immunol. 2004 Oct 15; 173(8):4967-75. Katsumoto T, Kimura M, Yamashita M, Hosokawa H, Hashimoto K, Hasegawa A, Omori M, Miyamoto T, Taniguchi M, Nakayama T. PMID: 15470039.
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    134. Interleukin (IL)-4-independent maintenance of histone modification of the IL-4 gene loci in memory Th2 cells. J Biol Chem. 2004 Sep 17; 279(38):39454-64. Yamashita M, Shinnakasu R, Nigo Y, Kimura M, Hasegawa A, Taniguchi M, Nakayama T. PMID: 15258154.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    135. Essential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene loci. J Biol Chem. 2004 Jun 25; 279(26):26983-90. Yamashita M, Ukai-Tadenuma M, Miyamoto T, Sugaya K, Hosokawa H, Hasegawa A, Kimura M, Taniguchi M, DeGregori J, Nakayama T. PMID: 15087456.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    136. Fas-disabling small exocyclic peptide mimetics limit apoptosis by an unexpected mechanism. Proc Natl Acad Sci U S A. 2004 Apr 27; 101(17):6599-604. Hasegawa A, Cheng X, Kajino K, Berezov A, Murata K, Nakayama T, Yagita H, Murali R, Greene MI. PMID: 15084739.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    137. Role of a NK receptor, KLRE-1, in bone marrow allograft rejection: analysis with KLRE-1-deficient mice. Blood. 2004 Aug 01; 104(3):781-3. Shimizu E, Koike J, Wakao H, Seino K, Koseki H, Kakiuchi T, Nakayama T, Taniguchi M. PMID: 15069013.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    138. CD28 costimulation controls histone hyperacetylation of the interleukin 5 gene locus in developing th2 cells. J Biol Chem. 2004 May 28; 279(22):23123-33. Inami M, Yamashita M, Tenda Y, Hasegawa A, Kimura M, Hashimoto K, Seki N, Taniguchi M, Nakayama T. PMID: 15039422.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    139. Impaired IFN-gamma production of Valpha24 NKT cells in non-remitting sarcoidosis. Int Immunol. 2004 Feb; 16(2):215-22. Kobayashi S, Kaneko Y, Seino K, Yamada Y, Motohashi S, Koike J, Sugaya K, Kuriyama T, Asano S, Tsuda T, Wakao H, Harada M, Kojo S, Nakayama T, Taniguchi M. PMID: 14734606.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    140. Down-regulation of the invariant Valpha14 antigen receptor in NKT cells upon activation. Int Immunol. 2004 Feb; 16(2):241-7. Harada M, Seino K, Wakao H, Sakata S, Ishizuka Y, Ito T, Kojo S, Nakayama T, Taniguchi M. PMID: 14734609.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    141. Bone marrow allograft rejection mediated by a novel murine NK receptor, NKG2I. J Exp Med. 2004 Jan 05; 199(1):137-44. Koike J, Wakao H, Ishizuka Y, Sato TA, Hamaoki M, Seino K, Koseki H, Nakayama T, Taniguchi M. PMID: 14707119.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    142. Critical role of Valpha14+ natural killer T cells in the innate phase of host protection against Streptococcus pneumoniae infection. Eur J Immunol. 2003 Dec; 33(12):3322-30. Kawakami K, Yamamoto N, Kinjo Y, Miyagi K, Nakasone C, Uezu K, Kinjo T, Nakayama T, Taniguchi M, Saito A. PMID: 14635040.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    143. CD69-null mice protected from arthritis induced with anti-type II collagen antibodies. Int Immunol. 2003 Aug; 15(8):987-92. Murata K, Inami M, Hasegawa A, Kubo S, Kimura M, Yamashita M, Hosokawa H, Nagao T, Suzuki K, Hashimoto K, Shinkai H, Koseki H, Taniguchi M, Ziegler SF, Nakayama T. PMID: 12882836.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    144. CD8 T cell-specific downregulation of histone hyperacetylation and gene activation of the IL-4 gene locus by ROG, repressor of GATA. Immunity. 2003 Aug; 19(2):281-94. Omori M, Yamashita M, Inami M, Ukai-Tadenuma M, Kimura M, Nigo Y, Hosokawa H, Hasegawa A, Taniguchi M, Nakayama T. PMID: 12932361.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    145. TH1-biased immunity induced by exposure to Antarctic winter. J Allergy Clin Immunol. 2003 Jun; 111(6):1353-60. Shirai T, Magara KK, Motohashi S, Yamashita M, Kimura M, Suwazomo Y, Nogawa K, Kuriyama T, Taniguchi M, Nakayama T. PMID: 12789239.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    146. Gamma interferon production by hepatic NK T cells during Escherichia coli infection is resistant to the inhibitory effects of oxidative stress. Infect Immun. 2003 May; 71(5):2468-77. Zhang G, Nichols RD, Taniguchi M, Nakayama T, Parmely MJ. PMID: 12704118.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    147. Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow. J Cell Biol. 2003 Apr 28; 161(2):417-27. Shimonaka M, Katagiri K, Nakayama T, Fujita N, Tsuruo T, Yoshie O, Kinashi T. PMID: 12707305.
      View in: PubMed   Mentions: 105     Fields:    Translation:AnimalsCells
    148. Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity. Nat Med. 2003 May; 9(5):582-8. Akbari O, Stock P, Meyer E, Kronenberg M, Sidobre S, Nakayama T, Taniguchi M, Grusby MJ, DeKruyff RH, Umetsu DT. PMID: 12669034.
      View in: PubMed   Mentions: 242     Fields:    Translation:AnimalsCells
    149. Expression of recombination-activating gene in mature peripheral T cells in Peyer's patch. Int Immunol. 2003 Mar; 15(3):393-402. Kondo E, Wakao H, Koseki H, Takemori T, Kojo S, Harada M, Takahashi M, Sakata S, Shimizu C, Ito T, Nakayama T, Taniguchi M. PMID: 12618483.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    150. Long term maintenance of IgE-mediated memory in mast cells in the absence of detectable serum IgE. J Immunol. 2003 Jan 15; 170(2):775-80. Kubo S, Nakayama T, Matsuoka K, Yonekawa H, Karasuyama H. PMID: 12517940.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    151. src homology 2 domain-containing tyrosine phosphatase SHP-1 controls the development of allergic airway inflammation. J Clin Invest. 2003 Jan; 111(1):109-19. Kamata T, Yamashita M, Kimura M, Murata K, Inami M, Shimizu C, Sugaya K, Wang CR, Taniguchi M, Nakayama T. PMID: 12511594.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    152. Preserved IFN-alpha production of circulating Valpha24 NKT cells in primary lung cancer patients. Int J Cancer. 2002 Nov 10; 102(2):159-65. Motohashi S, Kobayashi S, Ito T, Magara KK, Mikuni O, Kamada N, Iizasa T, Nakayama T, Fujisawa T, Taniguchi M. PMID: 12385012.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    153. Identification of a conserved GATA3 response element upstream proximal from the interleukin-13 gene locus. J Biol Chem. 2002 Nov 01; 277(44):42399-408. Yamashita M, Ukai-Tadenuma M, Kimura M, Omori M, Inami M, Taniguchi M, Nakayama T. PMID: 12205084.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    154. Ras activation in T cells determines the development of antigen-induced airway hyperresponsiveness and eosinophilic inflammation. J Immunol. 2002 Aug 15; 169(4):2134-40. Shibata Y, Kamata T, Kimura M, Yamashita M, Wang CR, Murata K, Miyazaki M, Taniguchi M, Watanabe N, Nakayama T. PMID: 12165542.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    155. T(h)1/T(h)2 cell differentiation of developing CD4 single-positive thymocytes. Int Immunol. 2002 Aug; 14(8):943-51. Kikkawa E, Yamashita M, Kimura M, Omori M, Sugaya K, Shimizu C, Katsumoto T, Ikekita M, Taniguchi M, Nakayama T. PMID: 12147631.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    156. CD4(+)CD25(+) T-cell development is regulated by at least 2 distinct mechanisms. Blood. 2002 Jan 15; 99(2):555-60. Suto A, Nakajima H, Ikeda K, Kubo S, Nakayama T, Taniguchi M, Saito Y, Iwamoto I. PMID: 11781238.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    157. The generation of mature, single-positive thymocytes in vivo is dysregulated by CD69 blockade or overexpression. J Immunol. 2002 Jan 01; 168(1):87-94. Nakayama T, Kasprowicz DJ, Yamashita M, Schubert LA, Gillard G, Kimura M, Didierlaurent A, Koseki H, Ziegler SF. PMID: 11751950.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    158. The regulatory role of Valpha14 NKT cells in innate and acquired immune response. Annu Rev Immunol. 2003; 21:483-513. Taniguchi M, Harada M, Kojo S, Nakayama T, Wakao H. PMID: 12543936.
      View in: PubMed   Mentions: 216     Fields:    Translation:HumansAnimalsCells
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