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    Shantanu Sinha

    TitleProfessor In Residence
    SchoolUniversity of California, San Diego
    Address9500 Gilman Drive #0852
    CA La Jolla 92093
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      Collapse Biography 
      Collapse Education and Training
      University of IllinoisPostdoc RA1984Physical Chemistry
      Indian Institute of SciencePostdoc1983Solid State Physics
      Indian Institute of SciencePh.D.1983Solid State Physics
      Indian Institute of TechnologyM.Sc.1977Physics
      Indian Institute of TechnologyB.Sc.1975Physics
      Collapse Awards and Honors
      AMSSM2000Best research paper award
      American Heart Association1995Laverna Titus Young Investigator
      NCERT, New Delhi1972  - 1983National Science Talent Scholarship

      Collapse Overview 

      Collapse Research 
      Collapse Research Activities and Funding
      In Vivo Imaging-Based Multiscale Modeling of Normal and Atrophied Human Lower Leg
      NIH/NIAMS R01AR053343Jul 15, 2006 - Jun 30, 2015
      Role: Principal Investigator
      NIH U41RR019703Sep 29, 2005 - Jul 31, 2010
      Role: Co-Investigator
      Brain Tumor Therapy: Radio Surgery vs. MR-Guided Ablat;
      NIH/NCI R21CA094226Jun 1, 2004 - May 31, 2006
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Malis V, Sinha U, Csapo R, Narici M, Sinha S. Relationship of changes in strain rate indices estimated from velocity-encoded MR imaging to loss of muscle force following disuse atrophy. Magn Reson Med. 2017 May 30. PMID: 28560822.
        View in: PubMed
      2. Kinugasa R, Yamamura N, Sinha S, Takagi S. Influence of intramuscular fiber orientation on the Achilles tendon curvature using three-dimensional finite element modeling of contracting skeletal muscle. J Biomech. 2016 Oct 03; 49(14):3592-3595. PMID: 27663620.
        View in: PubMed
      3. Ugarte V, Sinha U, Malis V, Csapo R, Sinha S. 3D multimodal spatial fuzzy segmentation of intramuscular connective and adipose tissue from ultrashort TE MR images of calf muscle. Magn Reson Med. 2017 Feb; 77(2):870-883. PMID: 26892499.
        View in: PubMed
      4. Csapo R, Malis V, Sinha U, Sinha S. Mapping of spatial and temporal heterogeneity of plantar flexor muscle activity during isometric contraction: correlation of velocity-encoded MRI with EMG. J Appl Physiol (1985). 2015 Sep 01; 119(5):558-68. PMID: 26112239; PMCID: PMC4556836.
      5. Sinha U, Malis V, Csapo R, Moghadasi A, Kinugasa R, Sinha S. Age-related differences in strain rate tensor of the medial gastrocnemius muscle during passive plantarflexion and active isometric contraction using velocity encoded MR imaging: potential index of lateral force transmission. Magn Reson Med. 2015 May; 73(5):1852-63. PMID: 25046255; PMCID: PMC4287463.
      6. Rajasekaran MR, Sinha S, Seo Y, Salehi M, Bhargava V, Mittal RK. Myoarchitectural and functional alterations in rabbit external anal sphincter muscle following experimental surgical trauma. Am J Physiol Gastrointest Liver Physiol. 2014 Aug 15; 307(4):G445-51. PMID: 24994856.
        View in: PubMed
      7. Csapo R, Malis V, Sinha U, Du J, Sinha S. Age-associated differences in triceps surae muscle composition and strength - an MRI-based cross-sectional comparison of contractile, adipose and connective tissue. BMC Musculoskelet Disord. 2014 Jun 17; 15:209. PMID: 24939372; PMCID: PMC4072482.
      8. Sinha U, Csapo R, Malis V, Xue Y, Sinha S. Age-related differences in diffusion tensor indices and fiber architecture in the medial and lateral gastrocnemius. J Magn Reson Imaging. 2015 Apr; 41(4):941-53. PMID: 24771672; PMCID: PMC4212021.
      9. Mittal RK, Bhargava V, Sheean G, Ledgerwood M, Sinha S. Purse-string morphology of external anal sphincter revealed by novel imaging techniques. Am J Physiol Gastrointest Liver Physiol. 2014 Mar; 306(6):G505-14. PMID: 24458022; PMCID: PMC3949029.
      10. Kinugasa R, Oda T, Komatsu T, Edgerton VR, Sinha S. Interaponeurosis shear strain modulates behavior of myotendinous junction of the human triceps surae. Physiol Rep. 2013 Nov; 1(6):e00147. PMID: 24400149; PMCID: PMC3871462.
      11. Csapo R, Hodgson J, Kinugasa R, Edgerton VR, Sinha S. Ankle morphology amplifies calcaneus movement relative to triceps surae muscle shortening. J Appl Physiol (1985). 2013 Aug 15; 115(4):468-73. PMID: 23743400; PMCID: PMC3742942.
      12. Sinha S, Shin DD, Hodgson JA, Kinugasa R, Edgerton VR. Computer-controlled, MR-compatible foot-pedal device to study dynamics of the muscle tendon complex under isometric, concentric, and eccentric contractions. J Magn Reson Imaging. 2012 Aug; 36(2):498-504. PMID: 22392816; PMCID: PMC3984931.
      13. Hodgson JA, Chi SW, Yang JP, Chen JS, Edgerton VR, Sinha S. Finite element modeling of passive material influence on the deformation and force output of skeletal muscle. J Mech Behav Biomed Mater. 2012 May; 9:163-83. PMID: 22498294; PMCID: PMC4075494.
      14. Kinugasa R, Hodgson JA, Edgerton VR, Sinha S. Asymmetric deformation of contracting human gastrocnemius muscle. J Appl Physiol (1985). 2012 Feb; 112(3):463-70. PMID: 22134691; PMCID: PMC3289422.
      15. Kinugasa R, Kawakami Y, Sinha S, Fukunaga T. Unique spatial distribution of in vivo human muscle activation. Exp Physiol. 2011 Sep; 96(9):938-48. PMID: 21666032.
        View in: PubMed
      16. Sinha S, Sinha U. Reproducibility analysis of diffusion tensor indices and fiber architecture of human calf muscles in vivo at 1.5 Tesla in neutral and plantarflexed ankle positions at rest. J Magn Reson Imaging. 2011 Jul; 34(1):107-19. PMID: 21608064; PMCID: PMC3121919.
      17. Sinha U, Sinha S, Hodgson JA, Edgerton RV. Human soleus muscle architecture at different ankle joint angles from magnetic resonance diffusion tensor imaging. J Appl Physiol (1985). 2011 Mar; 110(3):807-19. PMID: 21164150; PMCID: PMC3069630.
      18. Kinugasa R, Hodgson JA, Edgerton VR, Shin DD, Sinha S. Reduction in tendon elasticity from unloading is unrelated to its hypertrophy. J Appl Physiol (1985). 2010 Sep; 109(3):870-7. PMID: 20616227; PMCID: PMC2944640.
      19. Chi SW, Hodgson J, Chen JS, Reggie Edgerton V, Shin DD, Roiz RA, Sinha S. Finite element modeling reveals complex strain mechanics in the aponeuroses of contracting skeletal muscle. J Biomech. 2010 May 07; 43(7):1243-50. PMID: 20189180; PMCID: PMC2857665.
      20. Shin DD, Hodgson JA, Edgerton VR, Sinha S. In vivo intramuscular fascicle-aponeuroses dynamics of the human medial gastrocnemius during plantarflexion and dorsiflexion of the foot. J Appl Physiol (1985). 2009 Oct; 107(4):1276-84. PMID: 19608924; PMCID: PMC2763833.
      21. Sinha S, Sinha U. Recent advances in breast MRI and MRS. NMR Biomed. 2009 Jan; 22(1):3-16. PMID: 18654998.
        View in: PubMed
      22. Shin D, Finni T, Ahn S, Hodgson JA, Lee HD, Edgerton VR, Sinha S. In vivo estimation and repeatability of force-length relationship and stiffness of the human achilles tendon using phase contrast MRI. J Magn Reson Imaging. 2008 Oct; 28(4):1039-45. PMID: 18821605; PMCID: PMC2907260.
      23. Kinugasa R, Shin D, Yamauchi J, Mishra C, Hodgson JA, Edgerton VR, Sinha S. Phase-contrast MRI reveals mechanical behavior of superficial and deep aponeuroses in human medial gastrocnemius during isometric contraction. J Appl Physiol (1985). 2008 Oct; 105(4):1312-20. PMID: 18703759; PMCID: PMC2576031.
      24. Shin D, Finni T, Ahn S, Hodgson JA, Lee HD, Edgerton VR, Sinha S. Effect of chronic unloading and rehabilitation on human Achilles tendon properties: a velocity-encoded phase-contrast MRI study. J Appl Physiol (1985). 2008 Oct; 105(4):1179-86. PMID: 18687975; PMCID: PMC2576038.
      25. Wen H, Dou Z, Finni T, Havu M, Kang Z, Cheng S, Sipilä S, Sinha S, Usenius JP, Cheng S. Thigh muscle function in stroke patients revealed by velocity-encoded cine phase-contrast magnetic resonance imaging. Muscle Nerve. 2008 Jun; 37(6):736-44. PMID: 18335468.
        View in: PubMed
      26. Finni T, Havu M, Sinha S, Usenius JP, Cheng S. Mechanical behavior of the quadriceps femoris muscle tendon unit during low-load contractions. J Appl Physiol (1985). 2008 May; 104(5):1320-8. PMID: 18339890.
        View in: PubMed
      27. Ahn S, Shin D, Tateshima S, Tanishita K, Vinuela F, Sinha S. Fluid-induced wall shear stress in anthropomorphic brain aneurysm models: MR phase-contrast study at 3 T. J Magn Reson Imaging. 2007 Jun; 25(6):1120-30. PMID: 17520716.
        View in: PubMed
      28. Sinha S, Sinha U, Edgerton VR. In vivo diffusion tensor imaging of the human calf muscle. J Magn Reson Imaging. 2006 Jul; 24(1):182-90. PMID: 16729262.
        View in: PubMed
      29. Hodgson JA, Finni T, Lai AM, Edgerton VR, Sinha S. Influence of structure on the tissue dynamics of the human soleus muscle observed in MRI studies during isometric contractions. J Morphol. 2006 May; 267(5):584-601. PMID: 16453292.
        View in: PubMed
      30. Vogel-Claussen J, Finn JP, Gomes AS, Hundley GW, Jerosch-Herold M, Pearson G, Sinha S, Lima JA, Bluemke DA. Left ventricular papillary muscle mass: relationship to left ventricular mass and volumes by magnetic resonance imaging. J Comput Assist Tomogr. 2006 May-Jun; 30(3):426-32. PMID: 16778617.
        View in: PubMed
      31. Grinstead JW, Sinha S, Tateshima S, Nien YL, Vinuela F. Visualization and quantification of flow and velocity fields in intracranial arteriovenous malformations using phase-contrast MR angiography. AJR Am J Roentgenol. 2006 Feb; 186(2):553-5. PMID: 16423967.
        View in: PubMed
      32. Lee HD, Finni T, Hodgson JA, Lai AM, Edgerton VR, Sinha S. Soleus aponeurosis strain distribution following chronic unloading in humans: an in vivo MR phase-contrast study. J Appl Physiol (1985). 2006 Jun; 100(6):2004-11. PMID: 16424072.
        View in: PubMed
      33. Finni T, Hodgson JA, Lai AM, Edgerton VR, Sinha S. Muscle synergism during isometric plantarflexion in achilles tendon rupture patients and in normal subjects revealed by velocity-encoded cine phase-contrast MRI. Clin Biomech (Bristol, Avon). 2006 Jan; 21(1):67-74. PMID: 16194588.
        View in: PubMed
      34. Grinstead J, Sinha S. In-plane velocity encoding with coherent steady-state imaging. Magn Reson Med. 2005 Jul; 54(1):138-45. PMID: 15968674.
        View in: PubMed
      35. Bhidayasiri R, Bronstein JM, Sinha S, Krahl SE, Ahn S, Behnke EJ, Cohen MS, Frysinger R, Shellock FG. Bilateral neurostimulation systems used for deep brain stimulation: in vitro study of MRI-related heating at 1.5 T and implications for clinical imaging of the brain. Magn Reson Imaging. 2005 May; 23(4):549-55. PMID: 15919600.
        View in: PubMed
      36. Sinha S, Hodgson JA, Finni T, Lai AM, Grinstead J, Edgerton VR. Muscle kinematics during isometric contraction: development of phase contrast and spin tag techniques to study healthy and atrophied muscles. J Magn Reson Imaging. 2004 Dec; 20(6):1008-19. PMID: 15558560.
        View in: PubMed
      37. Sinha S, Sinha U. In vivo diffusion tensor imaging of the human prostate. Magn Reson Med. 2004 Sep; 52(3):530-7. PMID: 15334571.
        View in: PubMed
      38. Finni T, Hodgson JA, Lai AM, Edgerton VR, Sinha S. Mapping of movement in the isometrically contracting human soleus muscle reveals details of its structural and functional complexity. J Appl Physiol (1985). 2003 Nov; 95(5):2128-33. PMID: 12857769.
        View in: PubMed
      39. Finni T, Hodgson JA, Lai AM, Edgerton VR, Sinha S. Nonuniform strain of human soleus aponeurosis-tendon complex during submaximal voluntary contractions in vivo. J Appl Physiol (1985). 2003 Aug; 95(2):829-37. PMID: 12716873.
        View in: PubMed
      40. Sinha S, Sinha U. Functional magnetic resonance of human breast tumors: diffusion and perfusion imaging. Ann N Y Acad Sci. 2002 Dec; 980:95-115. PMID: 12594084.
        View in: PubMed
      41. Sinha S, Lucas-Quesada FA, Sinha U, DeBruhl N, Bassett LW. In vivo diffusion-weighted MRI of the breast: potential for lesion characterization. J Magn Reson Imaging. 2002 Jun; 15(6):693-704. PMID: 12112520.
        View in: PubMed
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