Fadel Zeidan

Title(s)Associate Professor, Anesthesiology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    The role of endogenous opioids in mindfulness-based chronic pain relief
    NIH R21AT010352Aug 9, 2019 - Jul 31, 2021
    Role: Principal Investigator
    Brain Mechanisms Supporting Mindfulness Meditation-Based Chronic Pain Relief
    NIH R01AT009693May 10, 2018 - Apr 30, 2023
    Role: Principal Investigator
    Brain Mechanisms Supporting Mindfulness-Based Pain Relief
    NIH R00AT008238Jul 1, 2014 - Feb 28, 2021
    Role: Principal Investigator
    Brain Mechanisms Supporting Mindfulness-Based Pain Relief
    NIH K99AT008238Jul 1, 2014 - Jan 31, 2017
    Role: Principal Investigator
    Delineating the Brain Mechanisms Supporting Modulation of Pain by Meditation
    NIH F32AT006949Jul 25, 2012 - Jul 24, 2014
    Role: Principal Investigator

    Collapse ORNG Applications 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. I feel your pain: Higher empathy is associated with higher posterior default mode network activity. bioRxiv. 2023 Oct 23. Oliva V, Riegner G, Dean J, Khatib L, Allen A, Barrows D, Chen C, Fuentes R, Jacobson A, Lopez C, Mosbey D, Reyes M, Ross J, Uvarova A, Liu T, Zeidan F. PMID: 37645854; PMCID: PMC10462016.
      View in: PubMed   Mentions:
    2. Effects of Savoring Meditation on Positive Emotions and Pain-Related Brain Function: A Mechanistic Randomized Controlled Trial in People With Rheumatoid Arthritis. medRxiv. 2023 Sep 08. Finan PH, Hunt C, Keaser ML, Smith K, Lerman S, Bingham CO, Barrett F, Garland EL, Zeidan F, Seminowicz DA. PMID: 37732231; PMCID: PMC10508795.
      View in: PubMed   Mentions:
    3. The Mindful Reappraisal of Pain Scale (MRPS): Validation of a New Measure of Psychological Mechanisms of Mindfulness-Based Analgesia. Mindfulness (N Y). 2023 Jan; 14(1):192-204. Garland EL, Roberts RL, Hanley AW, Zeidan F, Keefe FJ. PMID: 37901118; PMCID: PMC10611443.
      View in: PubMed   Mentions:
    4. A randomized pilot of eHealth mindful movement and breathing to improve gynecologic surgery outcomes. J Psychosoc Oncol. 2023; 41(3):251-266. Sohl SJ, Tooze JA, Levine BJ, Zeidan F, Wheeler A, Kelly M, Shalowitz D, Danhauer SC. PMID: 35900116; PMCID: PMC9883595.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Disentangling self from pain: mindfulness meditation-induced pain relief is driven by thalamic-default mode network decoupling. Pain. 2023 02 01; 164(2):280-291. Riegner G, Posey G, Oliva V, Jung Y, Mobley W, Zeidan F. PMID: 36095039; PMCID: PMC9823141.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    6. The Effects of Mindfulness-Based Stress Reduction on Trauma in Victims of Gun Violence: a Pilot Study. Mindfulness (N Y). 2022; 13(4):1032-1041. Khatib L, Riegner G, Dean JG, Oliva V, Cruanes G, Mulligan BA, Zeidan F. PMID: 35341090; PMCID: PMC8938160.
      View in: PubMed   Mentions: 1  
    7. The Role of Expectations and Endogenous Opioids in Mindfulness-Based Relief of Experimentally Induced Acute Pain. Psychosom Med. 2021 Jul-Aug 01; 83(6):549-556. Case L, Adler-Neal AL, Wells RE, Zeidan F. PMID: 33480666; PMCID: PMC8415135.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    8. Effectiveness of Mindfulness Meditation vs Headache Education for Adults With Migraine: A Randomized Clinical Trial. JAMA Intern Med. 2021 03 01; 181(3):317-328. Wells RE, O'Connell N, Pierce CR, Estave P, Penzien DB, Loder E, Zeidan F, Houle TT. PMID: 33315046; PMCID: PMC7737157.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    9. Response to Mukhdomi and Mukhdomi's letter to the editor. Reg Anesth Pain Med. 2021 06; 46(6):557-558. Castellanos JP, Woolley C, Bruno KA, Zeidan F, Halberstadt A, Furnish T. PMID: 33033159.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Pain relief for osteoarthritis through combined treatment (PROACT): Protocol for a randomized controlled trial of mindfulness meditation combined with transcranial direct current stimulation in non-Hispanic black and white adults with knee osteoarthritis. Contemp Clin Trials. 2020 11; 98:106159. Fillingim RB, Woods AJ, Ahn H, Wu SS, Redden DT, Lai S, Deshpande H, Deutsch G, Sibille KT, Staud R, Zeidan F, Goodin BR. PMID: 32992020; PMCID: PMC7686081.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    11. Neurophysiological Mechanisms Supporting Mindfulness Meditation-Based Pain Relief: an Updated Review. Curr Pain Headache Rep. 2020 Aug 17; 24(10):56. Jinich-Diamant A, Garland E, Baumgartner J, Gonzalez N, Riegner G, Birenbaum J, Case L, Zeidan F. PMID: 32803491.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    12. Chronic pain and psychedelics: a review and proposed mechanism of action. Reg Anesth Pain Med. 2020 07; 45(7):486-494. Castellanos JP, Woolley C, Bruno KA, Zeidan F, Halberstadt A, Furnish T. PMID: 32371500.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    13. Attention to breath sensations does not engage endogenous opioids to reduce pain. Pain. 2020 08; 161(8):1884-1893. Wells RE, Collier J, Posey G, Morgan A, Auman T, Strittmatter B, Magalhaes R, Adler-Neal A, McHaffie JG, Zeidan F. PMID: 32701847; PMCID: PMC7483215.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    14. Brain moderators supporting the relationship between depressive mood and pain. Pain. 2019 09; 160(9):2028-2035. Adler-Neal AL, Emerson NM, Farris SR, Jung Y, Coghill RC, Zeidan F. PMID: 31095097; PMCID: PMC6699932.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    15. The neural mechanisms of mindfulness-based pain relief: a functional magnetic resonance imaging-based review and primer. Pain Rep. 2019 Jul-Aug; 4(4):e759. Zeidan F, Baumgartner JN, Coghill RC. PMID: 31579851; PMCID: PMC6728003.
      View in: PubMed   Mentions: 20  
    16. The Role of Heart Rate Variability in Mindfulness-Based Pain Relief. J Pain. 2020 Mar - Apr; 21(3-4):306-323. Adler-Neal AL, Waugh CE, Garland EL, Shaltout HA, Diz DI, Zeidan F. PMID: 31377215; PMCID: PMC6994350.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    17. Brief mindfulness training enhances cognitive control in socioemotional contexts: Behavioral and neural evidence. PLoS One. 2019; 14(7):e0219862. Quaglia JT, Zeidan F, Grossenbacher PG, Freeman SP, Braun SE, Martelli A, Goodman RJ, Brown KW. PMID: 31323050; PMCID: PMC6641506.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    18. Iterative adaptation process for eHealth Mindful Movement and Breathing to improve gynecologic cancer surgery outcomes. Psychooncology. 2019 08; 28(8):1774-1777. Sohl SJ, Tooze JA, Wheeler A, Zeidan F, Wagner LI, Evans S, Kelly M, Shalowitz D, Green M, Levine B, Danhauer SC. PMID: 31219212; PMCID: PMC6746405.
      View in: PubMed   Mentions:    Fields:    
    19. Employing pain and mindfulness to understand consciousness: a symbiotic relationship. Curr Opin Psychol. 2019 08; 28:192-197. Grant JA, Zeidan F. PMID: 30776682; PMCID: PMC6616002.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    20. Brief Mindfulness-Based Interventions for Acute and Chronic Pain: A Systematic Review. J Altern Complement Med. 2019 Mar; 25(3):265-278. McClintock AS, McCarrick SM, Garland EL, Zeidan F, Zgierska AE. PMID: 30523705; PMCID: PMC6437625.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    21. Neural mechanisms supporting the relationship between dispositional mindfulness and pain. Pain. 2018 Dec; 159(12):2477-2485. Zeidan F, Salomons T, Farris SR, Emerson NM, Adler-Neal A, Jung Y, Coghill RC. PMID: 30015711; PMCID: PMC6237620.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    22. Trait Mindfulness Is Associated With Lower Pain Reactivity and Connectivity of the Default Mode Network. J Pain. 2019 06; 20(6):645-654. Harrison R, Zeidan F, Kitsaras G, Ozcelik D, Salomons TV. PMID: 30496832.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    23. Enhancement of Meditation Analgesia by Opioid Antagonist in Experienced Meditators. Psychosom Med. 2018 Nov/Dec; 80(9):807-813. May LM, Kosek P, Zeidan F, Berkman ET. PMID: 29595707; PMCID: PMC6162167.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    24. Mindfulness Meditation for Fibromyalgia: Mechanistic and Clinical Considerations. Curr Rheumatol Rep. 2017 Sep; 19(9):59. Adler-Neal AL, Zeidan F. PMID: 28752493; PMCID: PMC5693231.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    25. No, Mindfulness Meditation-Based Analgesia Is Not Mediated by Endogenous Opioids. Am J Med. 2016 11; 129(11):e297. Zeidan F. PMID: 27770844; PMCID: PMC5505568.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    26. Mindfulness meditation-based pain relief: a mechanistic account. Ann N Y Acad Sci. 2016 06; 1373(1):114-27. Zeidan F, Vago DR. PMID: 27398643; PMCID: PMC4941786.
      View in: PubMed   Mentions: 79     Fields:    Translation:Humans
    27. The brain on silent: mind wandering, mindful awareness, and states of mental tranquility. Ann N Y Acad Sci. 2016 06; 1373(1):96-113. Vago DR, Zeidan F. PMID: 27398642; PMCID: PMC5866730.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    28. Mindfulness-Meditation-Based Pain Relief Is Not Mediated by Endogenous Opioids. J Neurosci. 2016 Mar 16; 36(11):3391-7. Zeidan F, Adler-Neal AL, Wells RE, Stagnaro E, May LM, Eisenach JC, McHaffie JG, Coghill RC. PMID: 26985045; PMCID: PMC4792946.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    29. Mindfulness Meditation-Based Pain Relief Employs Different Neural Mechanisms Than Placebo and Sham Mindfulness Meditation-Induced Analgesia. J Neurosci. 2015 Nov 18; 35(46):15307-25. Zeidan F, Emerson NM, Farris SR, Ray JN, Jung Y, McHaffie JG, Coghill RC. PMID: 26586819; PMCID: PMC4649004.
      View in: PubMed   Mentions: 105     Fields:    Translation:Humans
    30. Brain mechanisms supporting violated expectations of pain. Pain. 2015 Sep; 156(9):1772-1785. Zeidan F, Lobanov OV, Kraft RA, Coghill RC. PMID: 26083664; PMCID: PMC4545679.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    31. Pain sensitivity is inversely related to regional grey matter density in the brain. Pain. 2014 Mar; 155(3):566-573. Emerson NM, Zeidan F, Lobanov OV, Hadsel MS, Martucci KT, Quevedo AS, Starr CJ, Nahman-Averbuch H, Weissman-Fogel I, Granovsky Y, Yarnitsky D, Coghill RC. PMID: 24333778; PMCID: PMC3944887.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    32. From cue to meaning: brain mechanisms supporting the construction of expectations of pain. Pain. 2014 Jan; 155(1):129-136. Lobanov OV, Zeidan F, McHaffie JG, Kraft RA, Coghill RC. PMID: 24055334; PMCID: PMC3947355.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    33. The downward spiral of chronic pain, prescription opioid misuse, and addiction: cognitive, affective, and neuropsychopharmacologic pathways. Neurosci Biobehav Rev. 2013 Dec; 37(10 Pt 2):2597-607. Garland EL, Froeliger B, Zeidan F, Partin K, Howard MO. PMID: 23988582; PMCID: PMC3967721.
      View in: PubMed   Mentions: 86     Fields:    Translation:Humans
    34. Neural correlates of mindfulness meditation-related anxiety relief. Soc Cogn Affect Neurosci. 2014 Jun; 9(6):751-9. Zeidan F, Martucci KT, Kraft RA, McHaffie JG, Coghill RC. PMID: 23615765; PMCID: PMC4040088.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    35. Functional connections between self-referential thought and chronic pain: a dysfunctional relationship. Pain. 2013 Jan; 154(1):3-4. Zeidan F, Coghill RC. PMID: 23159570.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Mindfulness meditation-related pain relief: evidence for unique brain mechanisms in the regulation of pain. Neurosci Lett. 2012 Jun 29; 520(2):165-73. Zeidan F, Grant JA, Brown CA, McHaffie JG, Coghill RC. PMID: 22487846; PMCID: PMC3580050.
      View in: PubMed   Mentions: 81     Fields:    Translation:Humans
    37. Brain mechanisms supporting the modulation of pain by mindfulness meditation. J Neurosci. 2011 Apr 06; 31(14):5540-8. Zeidan F, Martucci KT, Kraft RA, Gordon NS, McHaffie JG, Coghill RC. PMID: 21471390; PMCID: PMC3090218.
      View in: PubMed   Mentions: 187     Fields:    Translation:HumansCTClinical Trials
    38. Effects of brief and sham mindfulness meditation on mood and cardiovascular variables. J Altern Complement Med. 2010 Aug; 16(8):867-73. Zeidan F, Johnson SK, Gordon NS, Goolkasian P. PMID: 20666590.
      View in: PubMed   Mentions: 77     Fields:    Translation:Humans
    39. Mindfulness meditation improves cognition: evidence of brief mental training. Conscious Cogn. 2010 Jun; 19(2):597-605. Zeidan F, Johnson SK, Diamond BJ, David Z, Goolkasian P. PMID: 20363650.
      View in: PubMed   Mentions: 220     Fields:    Translation:HumansCTClinical Trials
    40. The effects of brief mindfulness meditation training on experimentally induced pain. J Pain. 2010 Mar; 11(3):199-209. Zeidan F, Gordon NS, Merchant J, Goolkasian P. PMID: 19853530.
      View in: PubMed   Mentions: 98     Fields:    Translation:Humans
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