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Elaine Muchmore

TitleProfessor Of Clinical
InstitutionUniversity of California San Diego
DepartmentMedicine
Address9500 Gilman Drive #9111-E
La Jolla CA 92093
Phone858-552-7444
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    Research Interests
    Dr. Muchmore has been active in delineating the effective components of resident supervision in the academic environment; she also maintains a small laboratory investigating the regulation of expression of selected cell surface sialic acid modifications. In her role as a clinician educator and administrator at the VA, she has worked with a small team to develop an electronic chart-based tool to measure the time spent performing direct and indirect supervision of resident trainees. It has been demonstrated that using this metric in outpatient settings, there is a direct correlation between direct supervision time required and stage of training. Her group is now working to launch use of this tool widely, with the goal of better assessing the quantity and quality of resident supervision in the academically-affiliated VA medical centers. She has also worked to define training milestones for Internal Medicine-based fellowships, and for Hematology/Oncology.

    Education and Training
    BS, MA - Biology, Stanford University - 1967-1972
    MD - University of California, Davis - 1975-1979
    Resident - Virginia Mason Hospital, Seattle - 1979-1982
    Fellow - Hematology-Oncology, University of California, San Diego - 1983-1987


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    Collapse Research Activities and Funding
    Detection of Non-Human Sialic Acid in Biotherapeutic Applications
    NIH/NIGMS R41GM080959Mar 7, 2008 - Mar 6, 2011
    Role: Principal Investigator
    N-ACETYLNEURAMINIC ACID HYDROXYLASE
    NIH/NIGMS R29GM043165Dec 1, 1989 - Jun 30, 1995
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Cornett PA, Williams C, Alweis RL, McConville J, Frank M, Dalal B, Kopelman RI, Luther VP, O'connor AB, Muchmore E. Problematic communications during 2016 fellowship recruitment in internal medicine. J Community Hosp Intern Med Perspect. 2017; 7(5):277-281. PMID: 29147467.
      View in: PubMed
    2. Collichio FA, Hess BJ, Muchmore E, Duhigg L, Lipner RS, Haist S, Hawley JL, Morrison CA, Clayton CP, Raymond MJ, Kayoumi KM, Gitlin SD. Medical Knowledge Assessment by Hematology and Medical Oncology In-Training Examinations Are Better Than Program Director Assessments at Predicting Subspecialty Certification Examination Performance. J Cancer Educ. 2017 Sep; 32(3):647-654. PMID: 26897634.
      View in: PubMed
    3. Chang J, Kwan B, Panjwani N, Villanueva N, Diamond S, Wong-Sefidan I, Muchmore E. Prostate adenocarcinoma metastases to the testis and brain: case report and review of the literature. Oxf Med Case Reports. 2017 Aug; 2017(8):omx042. PMID: 28845236.
      View in: PubMed
    4. Alweis R, Collichio F, Milne CK, Dalal B, Williams CM, Sulistio MS, Roth TK, Muchmore E. Guidelines for a Standardized Fellowship Letter of Recommendation. Am J Med. 2017 May; 130(5):606-611. PMID: 28189466.
      View in: PubMed
    5. von Gunten CF, Mullan PB, Nelesen R, Garman K, McNeal H, Savoia M, Muchmore E, Ikeda T, Amundson S, McKennett M, Diamant J, Pepper P, Gray C, Weissman D. Primary Care Residents Improve Knowledge, Skills, Attitudes, and Practice After a Clinical Curriculum With a Hospice. Am J Hosp Palliat Care. 2017 Sep; 34(8):713-720. PMID: 27353516.
      View in: PubMed
    6. Mink R, Caputo G, Fried E, Hofkosh D, Le-Bucklin KV, McMillan J, Muchmore E, Pryor A, Vargo D, Bale J. Delaying the Pediatric Fellowship Start Date to Improve Trainee Well-Being. J Pediatr. 2015 Aug; 167(2):222-3. PMID: 26210834.
      View in: PubMed
    7. Barrett JC, Alweis R, Frank M, O'Connor A, McConville JF, Adams ND, Arfons L, Bernard S, Bradley T, Buckley JD, Cohen E, Cornett P, Elkins S, Kopelman R, Luther VP, Petrusky J, McNeill DB, Omar B, Palapiano N, Roth T, Satko S, Fried ED, Muchmore E. Adoption of a Uniform Start Date for Internal Medicine Fellowships and Other Advanced Training: An AAIM White Paper. Am J Med. 2015 Sep; 128(9):1039-43. PMID: 26071819.
      View in: PubMed
    8. Collichio F, Kayoumi K, Sierra L, Clayton CP, Raymond M, Muchmore E. The Next Accreditation System: a strategy for implementing new reporting standards using a Hematology/Oncology model. Am J Med. 2015 Feb; 128(2):200-7. PMID: 25448172.
      View in: PubMed
    9. Kashner TM, Henley SS, Golden RM, Byrne JM, Keitz SA, Cannon GW, Chang BK, Holland GJ, Aron DC, Muchmore E, Wicker A, White H. Studying the effects of ACGME duty hours limits on resident satisfaction: results from VA learners' perceptions survey. Acad Med. 2010 Jul; 85(7):1130-9. PMID: 20592508.
      View in: PubMed
    10. Byrne JM, Kashner M, Gilman SC, Aron DC, Cannon GW, Chang BK, Godleski L, Golden RM, Henley SS, Holland GJ, Kaminetzky CP, Keitz SA, Kirsh S, Muchmore E, Wicker AB. Measuring the intensity of resident supervision in the department of veterans affairs: the resident supervision index. Acad Med. 2010 Jul; 85(7):1171-81. PMID: 20305532.
      View in: PubMed
    11. Kashner TM, Byrne JM, Henley SS, Golden RM, Aron DC, Cannon GW, Chang BK, Gilman SC, Holland GJ, Kaminetzky CP, Keitz SA, Muchmore E, Kashner TK, Wicker AB. Measuring progressive independence with the resident supervision index: theoretical approach. J Grad Med Educ. 2010 Mar; 2(1):8-16. PMID: 21975879; PMCID: PMC2931231.
    12. Kashner TM, Byrne JM, Chang BK, Henley SS, Golden RM, Aron DC, Cannon GW, Gilman SC, Holland GJ, Kaminetzky CP, Keitz SA, Muchmore E, Kashner TK, Wicker AB. Measuring progressive independence with the resident supervision index: empirical approach. J Grad Med Educ. 2010 Mar; 2(1):17-30. PMID: 21975880; PMCID: PMC2931230.
    13. Dosanjh A, Muchmore E. Expression of DeltaF508 Cystic Fibrosis Transmembrane Regulator (CFTR) Decreases Membrane Sialylation. Open Respir Med J. 2009 May 18; 3:79-84. PMID: 19572026; PMCID: PMC2703207.
    14. Gagneux P, Muchmore E. The chimpanzee model: contributions and considerations for studies of hepatitis B virus. Methods Mol Med. 2004; 96:289-318. PMID: 14762278.
      View in: PubMed
    15. Tangvoranuntakul P, Gagneux P, Diaz S, Bardor M, Varki N, Varki A, Muchmore E. Human uptake and incorporation of an immunogenic nonhuman dietary sialic acid. Proc Natl Acad Sci U S A. 2003 Oct 14; 100(21):12045-50. PMID: 14523234; PMCID: PMC218710.
    16. Enard W, Khaitovich P, Klose J, Zöllner S, Heissig F, Giavalisco P, Nieselt-Struwe K, Muchmore E, Varki A, Ravid R, Doxiadis GM, Bontrop RE, Pääbo S. Intra- and interspecific variation in primate gene expression patterns. Science. 2002 Apr 12; 296(5566):340-3. PMID: 11951044.
      View in: PubMed
    17. Muchmore E. Chimpanzee models for human disease and immunobiology. Immunol Rev. 2001 Oct; 183:86-93. PMID: 11782249.
      View in: PubMed
    18. Muchmore E, Diaz S, Varki A. A structural difference between the cell surfaces of humans and the great apes. Am J Phys Anthropol. 1998 Oct; 107(2):187-98. PMID: 9786333.
      View in: PubMed
    19. Chou HH, Takematsu H, Diaz S, Iber J, Nickerson E, Wright KL, Muchmore E, Nelson DL, Warren ST, Varki A. A mutation in human CMP-sialic acid hydroxylase occurred after the Homo-Pan divergence. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11751-6. PMID: 9751737; PMCID: PMC21712.
    20. Muchmore E. Developmental sialic acid modifications in rat organs. Glycobiology. 1992 Aug; 2(4):337-43. PMID: 1421755.
      View in: PubMed
    21. Muchmore E, Milewski M, Varki A, Diaz S. Biosynthesis of N-glycolyneuraminic acid. The primary site of hydroxylation of N-acetylneuraminic acid is the cytosolic sugar nucleotide pool. J Biol Chem. 1989 Dec 05; 264(34):20216-23. PMID: 2684973.
      View in: PubMed
    22. Muchmore E, Varki NM, Fukuda M, Varki A. Developmental regulation of sialic acid modifications in rat and human colon. FASEB J. 1987 Sep; 1(3):229-35. PMID: 3623000.
      View in: PubMed
    23. Muchmore E, Varki A. Selective inactivation of influenza C esterase: a probe for detecting 9-O-acetylated sialic acids. Science. 1987 Jun 05; 236(4806):1293-5. PMID: 3589663.
      View in: PubMed