Daniel Donoghue

Title(s)Professor, Chemistry and Biochemistry
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
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    Abberant Activation of FGFR3 Signaling in Human Cancer
    NIH R01CA090900May 1, 2003 - Apr 30, 2009
    Role: Principal Investigator
    Regulation of Receptor Tyrosine Kinases
    NIH R01GM065490Jul 1, 2002 - Jun 30, 2006
    Role: Principal Investigator
    Transmembrane Domains of Receptor Tyrosine Kinases
    NIH R01GM061163Jul 1, 2001 - Jun 30, 2002
    Role: Principal Investigator
    Biochemistry of Growth Regulation and Oncogenesis
    NIH T32CA009523Jul 1, 1985 - Mar 31, 2026
    Role: Principal Investigator
    MOLECULAR STUDIES OF TRANSFORMING GROWTH FACTORS
    NIH R01DE012581Jul 1, 1985 - Jul 31, 2002
    Role: Principal Investigator
    MOLECULAR STUDIES OF TRANSFORMING GROWTH FACTORS
    NIH R01CA040573Jul 1, 1985 - Jun 30, 1997
    Role: Principal Investigator
    EXPRESSION OF RETROVIRAL ENVELOPE GENE FUSION PROTEINS
    NIH R01CA034456Apr 1, 1983 - Apr 30, 2001
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. BCR-ABL: The molecular mastermind behind chronic myeloid leukemia. Cytokine Growth Factor Rev. 2025 May 10. Shammas T, Peiris MN, Meyer AN, Donoghue DJ. PMID: 40360311.
      View in: PubMed   Mentions:    Fields:    
    2. Precision genome editing and in-cell measurements of oxidative DNA damage repair enable functional and mechanistic characterization of cancer-associated MUTYH variants. Nucleic Acids Res. 2025 Mar 20; 53(6). Vasquez CA, Osgood NRB, Zepeda MU, Sandel DK, Cowan QT, Peiris MN, Donoghue DJ, Komor AC. PMID: 40156857; PMCID: PMC11952967.
      View in: PubMed   Mentions:    Fields:    
    3. The oncogenic fusion protein EML4-NTRK3 requires three salt bridges for stability and biological activity. Heliyon. 2024 Aug 30; 10(16):e36278. Jiang Z, Meyer AN, Yang W, Donoghue DJ. PMID: 39253179; PMCID: PMC11381775.
      View in: PubMed   Mentions:
    4. Critical domains for NACC2-NTRK2 fusion protein activation. PLoS One. 2024; 19(6):e0301730. Yang W, Meyer AN, Jiang Z, Jiang X, Donoghue DJ. PMID: 38935636; PMCID: PMC11210774.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Oncogenic driver FGFR3-TACC3 requires five coiled-coil heptads for activation and disulfide bond formation for stability. Oncotarget. 2023 02 11; 14:133-145. Wang CG, Peiris MN, Meyer AN, Nelson KN, Donoghue DJ. PMID: 36780330; PMCID: PMC9924825.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. Nefarious NTRK oncogenic fusions in pediatric sarcomas: Too many to Trk. Cytokine Growth Factor Rev. 2022 12; 68:93-106. Aepala MR, Peiris MN, Jiang Z, Yang W, Meyer AN, Donoghue DJ. PMID: 36153202.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    7. Proteomic analysis reveals dual requirement for Grb2 and PLCγ1 interactions for BCR-FGFR1-Driven 8p11 cell proliferation. Oncotarget. 2022; 13:659-676. Peiris MN, Meyer AN, Warda D, Campos AR, Donoghue DJ. PMID: 35574218; PMCID: PMC9093983.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    8. Fibroblast growth factor receptor 4 promotes glioblastoma progression: a central role of integrin-mediated cell invasiveness. Acta Neuropathol Commun. 2022 04 28; 10(1):65. Gabler L, Jaunecker CN, Katz S, van Schoonhoven S, Englinger B, Pirker C, Mohr T, Vician P, Stojanovic M, Woitzuck V, Laemmerer A, Kirchhofer D, Mayr L, LaFranca M, Erhart F, Grissenberger S, Wenninger-Weinzierl A, Sturtzel C, Kiesel B, Lang A, Marian B, Grasl-Kraupp B, Distel M, Schüler J, Gojo J, Grusch M, Spiegl-Kreinecker S, Donoghue DJ, Lötsch D, Berger W. PMID: 35484633; PMCID: PMC9052585.
      View in: PubMed   Mentions: 10     Fields:    
    9. Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment. Oncotarget. 2021 Jan 05; 12(1):22-36. Ko J, Meyer AN, Haas M, Donoghue DJ. PMID: 33456711; PMCID: PMC7800776.
      View in: PubMed   Mentions: 8     Fields:    
    10. Typical achondroplasia secondary to a unique insertional variant of FGFR3 with in vitro demonstration of its effect on FGFR3 function. Am J Med Genet A. 2021 03; 185(3):798-805. Meyer AN, Modaff P, Wang CG, Wohler E, Sobreira NL, Donoghue DJ, Pauli RM. PMID: 33368972; PMCID: PMC8083996.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    11. Oncogenic fusion protein FGFR2-PPHLN1: Requirements for biological activation, and efficacy of inhibitors. Transl Oncol. 2020 Dec; 13(12):100853. Li F, Meyer AN, Peiris MN, Nelson KN, Donoghue DJ. PMID: 32854034; PMCID: PMC7451725.
      View in: PubMed   Mentions: 3  
    12. Carvacrol attenuates Campylobacter jejuni colonization factors and proteome critical for persistence in the chicken gut. Poult Sci. 2020 Sep; 99(9):4566-4577. Wagle BR, Donoghue AM, Shrestha S, Upadhyaya I, Arsi K, Gupta A, Liyanage R, Rath NC, Donoghue DJ, Upadhyay A. PMID: 32868001; PMCID: PMC7598144.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    13. Characterization of iPS87, a prostate cancer stem cell-like cell line. Oncotarget. 2020 Mar 24; 11(12):1075-1084. Assoun EN, Meyer AN, Jiang MY, Baird SM, Haas M, Donoghue DJ. PMID: 32256979; PMCID: PMC7105161.
      View in: PubMed   Mentions: 4     Fields:    
    14. Draft Genome Sequences of Campylobacter jejuni Strains Isolated from Poultry. Microbiol Resour Announc. 2020 Feb 13; 9(7). Wagle BR, Marasini D, Upadhyaya I, Shrestha S, Arsi K, Donoghue AM, Carbonero F, Donoghue DJ, Maas K, Upadhyay A. PMID: 32054706; PMCID: PMC7019061.
      View in: PubMed   Mentions: 3  
    15. Functions of FGFR2 corrupted by translocations in intrahepatic cholangiocarcinoma. Cytokine Growth Factor Rev. 2020 04; 52:56-67. Li F, Peiris MN, Donoghue DJ. PMID: 31899106.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimals
    16. Carvacrol antimicrobial wash treatments reduce Campylobacter jejuni and aerobic bacteria on broiler chicken skin. Poult Sci. 2019 Sep 01; 98(9):4073-4083. Shrestha S, Wagle BR, Upadhyay A, Arsi K, Donoghue DJ, Donoghue AM. PMID: 30993343.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCellsPHPublic Health
    17. Oncogenic fusion protein BCR-FGFR1 requires the breakpoint cluster region-mediated oligomerization and chaperonin Hsp90 for activation. Haematologica. 2020 05; 105(5):1262-1273. Peiris MN, Meyer AN, Nelson KN, Bisom-Rapp EW, Donoghue DJ. PMID: 31439673; PMCID: PMC7193502.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    18. Trans-Cinnamaldehyde, Eugenol and Carvacrol Reduce Campylobacter jejuni Biofilms and Modulate Expression of Select Genes and Proteins. Front Microbiol. 2019; 10:1837. Wagle BR, Upadhyay A, Upadhyaya I, Shrestha S, Arsi K, Liyanage R, Venkitanarayanan K, Donoghue DJ, Donoghue AM. PMID: 31456771; PMCID: PMC6698798.
      View in: PubMed   Mentions: 28  
    19. BCR: a promiscuous fusion partner in hematopoietic disorders. Oncotarget. 2019 Apr 12; 10(28):2738-2754. Peiris MN, Li F, Donoghue DJ. PMID: 31105873; PMCID: PMC6505627.
      View in: PubMed   Mentions: 13     Fields:    
    20. Edible Coatings Fortified With Carvacrol Reduce Campylobacter jejuni on Chicken Wingettes and Modulate Expression of Select Virulence Genes. Front Microbiol. 2019; 10:583. Shrestha S, Wagle BR, Upadhyay A, Arsi K, Upadhyaya I, Donoghue DJ, Donoghue AM. PMID: 30984132; PMCID: PMC6448016.
      View in: PubMed   Mentions: 7  
    21. Pectin or chitosan coating fortified with eugenol reduces Campylobacter jejuni on chicken wingettes and modulates expression of critical survival genes. Poult Sci. 2019 Mar 01; 98(3):1461-1471. Wagle BR, Upadhyay A, Shrestha S, Arsi K, Upadhyaya I, Donoghue AM, Donoghue DJ. PMID: 30407605; PMCID: PMC6377438.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCellsPHPublic Health
    22. Oncogenic mutations in IKKβ function through global changes induced by K63-linked ubiquitination and result in autocrine stimulation. PLoS One. 2018; 13(10):e0206014. Meyer AN, Gallo LH, Ko J, Cardenas G, Nelson KN, Siari A, Campos AR, Whisenant TC, Donoghue DJ. PMID: 30335863; PMCID: PMC6193727.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    23. Oncogenic driver FGFR3-TACC3 is dependent on membrane trafficking and ERK signaling. Oncotarget. 2018 Sep 28; 9(76):34306-34319. Nelson KN, Meyer AN, Wang CG, Donoghue DJ. PMID: 30344944; PMCID: PMC6188140.
      View in: PubMed   Mentions: 20     Fields:    
    24. RAS at the Golgi antagonizes malignant transformation through PTPRκ-mediated inhibition of ERK activation. Nat Commun. 2018 09 05; 9(1):3595. Casar B, Badrock AP, Jiménez I, Arozarena I, Colón-Bolea P, Lorenzo-Martín LF, Barinaga-Rementería I, Barriuso J, Cappitelli V, Donoghue DJ, Bustelo XR, Hurlstone A, Crespo P. PMID: 30185827; PMCID: PMC6125387.
      View in: PubMed   Mentions: 12     Fields:    
    25. Phytochemicals reduce aflatoxin-induced toxicity in chicken embryos. Poult Sci. 2017 Oct 01; 96(10):3725-3732. Yin HB, Chen CH, Darre MJ, Donoghue AM, Donoghue DJ, Venkitanarayanan K. PMID: 28938783.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    26. Gene Expression Response of Salmonella enterica Serotype Enteritidis Phage Type 8 to Subinhibitory Concentrations of the Plant-Derived Compounds Trans-Cinnamaldehyde and Eugenol. Front Microbiol. 2017; 8:1828. Kollanoor Johny A, Frye JG, Donoghue A, Donoghue DJ, Porwollik S, McClelland M, Venkitanarayanan K. PMID: 29018419; PMCID: PMC5623010.
      View in: PubMed   Mentions: 15  
    27. β-Resorcylic Acid, a Phytophenolic Compound, Reduces Campylobacter jejuni in Postharvest Poultry. J Food Prot. 2017 08; 80(8):1243-1251. Wagle BR, Arsi K, Upadhyay A, Shrestha S, Venkitanarayanan K, Donoghue AM, Donoghue DJ. PMID: 28686495.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    28. Trans-Cinnamaldehyde, Carvacrol, and Eugenol Reduce Campylobacter jejuni Colonization Factors and Expression of Virulence Genes in Vitro. Front Microbiol. 2017; 8:713. Upadhyay A, Arsi K, Wagle BR, Upadhyaya I, Shrestha S, Donoghue AM, Donoghue DJ. PMID: 28487683; PMCID: PMC5403884.
      View in: PubMed   Mentions: 31  
    29. Application of β-Resorcylic Acid as Potential Antimicrobial Feed Additive to Reduce Campylobacter Colonization in Broiler Chickens. Front Microbiol. 2017; 8:599. Wagle BR, Upadhyay A, Arsi K, Shrestha S, Venkitanarayanan K, Donoghue AM, Donoghue DJ. PMID: 28428779; PMCID: PMC5382206.
      View in: PubMed   Mentions: 18  
    30. The importance of regulatory ubiquitination in cancer and metastasis. Cell Cycle. 2017 Apr 03; 16(7):634-648. Gallo LH, Ko J, Donoghue DJ. PMID: 28166483; PMCID: PMC5397262.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimalsCells
    31. Receptor Tyrosine Kinases: Translocation Partners in Hematopoietic Disorders. Trends Mol Med. 2017 01; 23(1):59-79. Nelson KN, Peiris MN, Meyer AN, Siari A, Donoghue DJ. PMID: 27988109.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    32. Visualization of early prostatic adenocarcinoma as a stem cell disease. Oncotarget. 2016 Nov 15; 7(46):76159-76168. Jiang MY, Lee TL, Hao SS, Mahooti S, Baird SM, Donoghue DJ, Haas M. PMID: 27764770; PMCID: PMC5342804.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    33. Oncogenic Gene Fusion FGFR3-TACC3 Is Regulated by Tyrosine Phosphorylation. Mol Cancer Res. 2016 05; 14(5):458-69. Nelson KN, Meyer AN, Siari A, Campos AR, Motamedchaboki K, Donoghue DJ. PMID: 26869289.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    34. Functions of Fibroblast Growth Factor Receptors in cancer defined by novel translocations and mutations. Cytokine Growth Factor Rev. 2015 Aug; 26(4):425-49. Gallo LH, Nelson KN, Meyer AN, Donoghue DJ. PMID: 26003532.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    35. Intracloacal inoculation, an effective screening method for determining the efficacy of probiotic bacterial isolates against Campylobacter colonization in broiler chickens. J Food Prot. 2015 Jan; 78(1):209-13. Arsi K, Donoghue AM, Woo-Ming A, Blore PJ, Donoghue DJ. PMID: 25581198.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    36. Fibroblast growth factor receptor 3 interacts with and activates TGFβ-activated kinase 1 tyrosine phosphorylation and NFκB signaling in multiple myeloma and bladder cancer. PLoS One. 2014; 9(1):e86470. Salazar L, Kashiwada T, Krejci P, Meyer AN, Casale M, Hallowell M, Wilcox WR, Donoghue DJ, Thompson LM. PMID: 24466111; PMCID: PMC3900522.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    37. Novel Lys63-linked ubiquitination of IKKβ induces STAT3 signaling. Cell Cycle. 2014; 13(24):3964-76. Gallo LH, Meyer AN, Motamedchaboki K, Nelson KN, Haas M, Donoghue DJ. PMID: 25486864; PMCID: PMC4615003.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    38. Tyrosine phosphorylation allows integration of multiple signaling inputs by IKKβ. PLoS One. 2013; 8(12):e84497. Meyer AN, Drafahl KA, McAndrew CW, Gilda JE, Gallo LH, Haas M, Brill LM, Donoghue DJ. PMID: 24386391; PMCID: PMC3873999.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    39. Suppression of severe achondroplasia with developmental delay and acanthosis nigricans by the p.Thr651Pro mutation. Am J Med Genet A. 2014 Jan; 164A(1):243-50. Manickam K, Donoghue DJ, Meyer AN, Snyder PJ, Prior TW. PMID: 24352917.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    40. Early human prostate adenocarcinomas harbor androgen-independent cancer cells. PLoS One. 2013; 8(9):e74438. Fiñones RR, Yeargin J, Lee M, Kaur AP, Cheng C, Sun P, Wu C, Nguyen C, Wang-Rodriguez J, Meyer AN, Baird SM, Donoghue DJ, Haas M. PMID: 24086346; PMCID: PMC3783414.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    41. Targeting motility properties of bacteria in the development of probiotic cultures against Campylobacter jejuni in broiler chickens. Foodborne Pathog Dis. 2013 May; 10(5):435-41. Aguiar VF, Donoghue AM, Arsi K, Reyes-Herrera I, Metcalf JH, de los Santos FS, Blore PJ, Donoghue DJ. PMID: 23531121.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    42. Use of plant-derived antimicrobials for improving the safety of poultry products. Poult Sci. 2013 Feb; 92(2):493-501. Venkitanarayanan K, Kollanoor-Johny A, Darre MJ, Donoghue AM, Donoghue DJ. PMID: 23300319.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCellsPHPublic Health
    43. KIDs rule: regulatory phosphorylation of RTKs. Trends Biochem Sci. 2013 Feb; 38(2):75-84. Locascio LE, Donoghue DJ. PMID: 23312584.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    44. Caprylic acid reduces Salmonella Enteritidis populations in various segments of digestive tract and internal organs of 3- and 6-week-old broiler chickens, therapeutically. Poult Sci. 2012 Jul; 91(7):1686-94. Kollanoor-Johny A, Mattson T, Baskaran SA, Amalaradjou MA, Hoagland TA, Darre MJ, Khan MI, Schreiber DT, Donoghue AM, Donoghue DJ, Venkitanarayanan K. PMID: 22700516.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    45. The tumor suppressor tuberin regulates mitotic onset through the cellular localization of cyclin B1. Cell Cycle. 2011 Sep 15; 10(18):3129-39. Fidalgo da Silva E, Ansari SB, Maimaiti J, Barnes EA, Kong-Beltran M, Donoghue DJ, Porter LA. PMID: 21900748.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    46. The relationship between blood and muscle samples to monitor for residues of the antibiotic enrofloxacin in chickens. Poult Sci. 2011 Feb; 90(2):481-5. Reyes-Herrera I, Schneider MJ, Blore PJ, Donoghue DJ. PMID: 21248347.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsPHPublic Health
    47. Water administration of the medium-chain fatty acid caprylic acid produced variable efficacy against enteric Campylobacter colonization in broilers. Poult Sci. 2011 Feb; 90(2):494-7. Metcalf JH, Donoghue AM, Venkitanarayanan K, Reyes-Herrera I, Aguiar VF, Blore PJ, Donoghue DJ. PMID: 21248350.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    48. Multiplex PCR assay for the detection and quantification of Campylobacter spp., Escherichia coli O157:H7, and Salmonella serotypes in water samples. FEMS Microbiol Lett. 2011 Mar; 316(1):7-15. Park SH, Hanning I, Jarquin R, Moore P, Donoghue DJ, Donoghue AM, Ricke SC. PMID: 21204924.
      View in: PubMed   Mentions: 12     Fields:    Translation:CellsPHPublic Health
    49. The receptor tyrosine kinase FGFR4 negatively regulates NF-kappaB signaling. PLoS One. 2010 Dec 22; 5(12):e14412. Drafahl KA, McAndrew CW, Meyer AN, Haas M, Donoghue DJ. PMID: 21203561; PMCID: PMC3008709.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    50. Evaluation of Salmonella-vectored Campylobacter peptide epitopes for reduction of Campylobacter jejuni in broiler chickens. Clin Vaccine Immunol. 2011 Mar; 18(3):449-54. Layton SL, Morgan MJ, Cole K, Kwon YM, Donoghue DJ, Hargis BM, Pumford NR. PMID: 21177910; PMCID: PMC3067390.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    51. Caprylic Acid reduces enteric campylobacter colonization in market-aged broiler chickens but does not appear to alter cecal microbial populations. J Food Prot. 2010 Feb; 73(2):251-7. Solís de los Santos F, Hume M, Venkitanarayanan K, Donoghue AM, Hanning I, Slavik MF, Aguiar VF, Metcalf JH, Reyes-Herrera I, Blore PJ, Donoghue DJ. PMID: 20132669.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    52. A new family of receptor tyrosine kinases with a venus flytrap binding domain in insects and other invertebrates activated by aminoacids. PLoS One. 2009 May 21; 4(5):e5651. Ahier A, Rondard P, Gouignard N, Khayath N, Huang S, Trolet J, Donoghue DJ, Gauthier M, Pin JP, Dissous C. PMID: 19461966; PMCID: PMC2680970.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    53. Campylobacter biofilm phenotype exhibits reduced colonization potential in young chickens and altered in vitro virulence. Poult Sci. 2009 May; 88(5):1102-7. Hanning I, Donoghue DJ, Jarquin R, Kumar GS, Aguiar VF, Metcalf JH, Reyes-Herrera I, Slavik M. PMID: 19359701.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    54. Prophylactic supplementation of caprylic acid in feed reduces Salmonella enteritidis colonization in commercial broiler chicks. J Food Prot. 2009 Apr; 72(4):722-7. Johny AK, Baskaran SA, Charles AS, Amalaradjou MA, Darre MJ, Khan MI, Hoagland TA, Schreiber DT, Donoghue AM, Donoghue DJ, Venkitanarayanan K. PMID: 19435218.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    55. The atypical CDK activator Spy1 regulates the intrinsic DNA damage response and is dependent upon p53 to inhibit apoptosis. Cell Cycle. 2009 Jan 01; 8(1):66-75. McAndrew CW, Gastwirt RF, Donoghue DJ. PMID: 19106603; PMCID: PMC2782695.
      View in: PubMed   Mentions: 19     Fields:    
    56. The natural feed additive caprylic acid decreases Campylobacter jejuni colonization in market-aged broiler chickens. Poult Sci. 2009 Jan; 88(1):61-4. Solis de los Santos F, Donoghue AM, Venkitanarayanan K, Metcalf JH, Reyes-Herrera I, Dirain ML, Aguiar VF, Blore PJ, Donoghue DJ. PMID: 19096058.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    57. Nordihydroguaiaretic acid inhibits an activated fibroblast growth factor receptor 3 mutant and blocks downstream signaling in multiple myeloma cells. Cancer Res. 2008 Sep 15; 68(18):7362-70. Meyer AN, McAndrew CW, Donoghue DJ. PMID: 18794123; PMCID: PMC2745924.
      View in: PubMed   Mentions: 18     Fields:    
    58. Therapeutic supplementation of caprylic acid in feed reduces Campylobacter jejuni colonization in broiler chicks. Appl Environ Microbiol. 2008 Jul; 74(14):4564-6. Solis de los Santos F, Donoghue AM, Venkitanarayanan K, Reyes-Herrera I, Metcalf JH, Dirain ML, Aguiar VF, Blore PJ, Donoghue DJ. PMID: 18502935; PMCID: PMC2493180.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCellsPHPublic Health
    59. The Spy1/RINGO family represents a novel mechanism regulating mammary growth and tumorigenesis. Cancer Res. 2008 May 15; 68(10):3591-600. Golipour A, Myers D, Seagroves T, Murphy D, Evan GI, Donoghue DJ, Moorehead RA, Porter LA. PMID: 18483240.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    60. Caprylic acid supplemented in feed reduces enteric Campylobacter jejuni colonization in ten-day-old broiler chickens. Poult Sci. 2008 Apr; 87(4):800-4. Solis de Los Santos F, Donoghue AM, Venkitanarayanan K, Dirain ML, Reyes-Herrera I, Blore PJ, Donoghue DJ. PMID: 18340004.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    61. Antibiotic residues distribute uniformly in broiler chicken breast muscle tissue. J Food Prot. 2008 Jan; 71(1):223-5. Reyes-Herrera I, Donoghue DJ. PMID: 18236689.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsPHPublic Health
    62. Evaluation of serum as a potential matrix for multiresidue determination of fluoroquinolone antibiotics in chicken using liquid chromatography-fluorescence-mass spectrometry(n). J AOAC Int. 2007 Nov-Dec; 90(6):1716-23. Schneider MJ, Reyes-Herrera I, Donoghue DJ. PMID: 18193751.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsPHPublic Health
    63. Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27. Cell Cycle. 2007 Aug 01; 6(15):1937-45. McAndrew CW, Gastwirt RF, Meyer AN, Porter LA, Donoghue DJ. PMID: 17671428.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    64. Speedy/RINGO regulation of CDKs in cell cycle, checkpoint activation and apoptosis. Cell Cycle. 2007 May 15; 6(10):1188-93. Gastwirt RF, McAndrew CW, Donoghue DJ. PMID: 17507798.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    65. Gastrointestinal maturation is accelerated in turkey poults supplemented with a mannan-oligosaccharide yeast extract (Alphamune). Poult Sci. 2007 May; 86(5):921-30. Solis de los Santos F, Donoghue AM, Farnell MB, Huff GR, Huff WE, Donoghue DJ. PMID: 17435027.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    66. Performance and condemnation rate analysis of commercial turkey flocks treated with a Lactobacillus spp.-based probiotic. Poult Sci. 2007 Mar; 86(3):444-6. Torres-Rodriguez A, Donoghue AM, Donoghue DJ, Barton JT, Tellez G, Hargis BM. PMID: 17297154.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    67. Upregulation of oxidative burst and degranulation in chicken heterophils stimulated with probiotic bacteria. Poult Sci. 2006 Nov; 85(11):1900-6. Farnell MB, Donoghue AM, de Los Santos FS, Blore PJ, Hargis BM, Tellez G, Donoghue DJ. PMID: 17032821.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    68. Effect of oral administration of bismuth compounds on Campylobacter colonization in broilers. Poult Sci. 2006 Nov; 85(11):2009-11. Farnell MB, Donoghue AM, de Los Santos FS, Reyes-Herrera I, Cole K, Dirain ML, Blore PJ, Pandya K, Donoghue DJ. PMID: 17032837.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCellsPHPublic Health
    69. Spy1 expression prevents normal cellular responses to DNA damage: inhibition of apoptosis and checkpoint activation. J Biol Chem. 2006 Nov 17; 281(46):35425-35. Gastwirt RF, Slavin DA, McAndrew CW, Donoghue DJ. PMID: 16951407.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    70. Bacteriocins reduce Campylobacter colonization and alter gut morphology in turkey poults. Poult Sci. 2006 Sep; 85(9):1570-5. Cole K, Farnell MB, Donoghue AM, Stern NJ, Svetoch EA, Eruslanov BN, Volodina LI, Kovalev YN, Perelygin VV, Mitsevich EV, Mitsevich IP, Levchuk VP, Pokhilenko VD, Borzenkov VN, Svetoch OE, Kudryavtseva TY, Reyes-Herrera I, Blore PJ, Solis de los Santos F, Donoghue DJ. PMID: 16977842.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    71. Simultaneous determination of fluoroquinolones and tetracyclines in chicken muscle using HPLC with fluorescence detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Feb 01; 846(1-2):8-13. Schneider MJ, Braden SE, Reyes-Herrera I, Donoghue DJ. PMID: 16931182.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    72. Efficacy of iron chelators on Campylobacter concentrations in turkey semen. Poult Sci. 2006 Aug; 85(8):1462-5. Cole K, Donoghue AM, Reyes-Herrera I, Rath N, Donoghue DJ. PMID: 16903479.
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    73. Concentrations of antibiotic residues vary between different edible muscle tissues in poultry. J Food Prot. 2005 Oct; 68(10):2217-9. Reyes-Herrera I, Schneider MJ, Cole K, Farnell MB, Blore PJ, Donoghue DJ. PMID: 16245733.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsPHPublic Health
    74. Use of a specific bacteriophage treatment to reduce Salmonella in poultry products. Poult Sci. 2005 Jul; 84(7):1141-5. Higgins JP, Higgins SE, Guenther KL, Huff W, Donoghue AM, Donoghue DJ, Hargis BM. PMID: 16050131.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCellsPHPublic Health
    75. Constitutively activated FGFR3 mutants signal through PLCgamma-dependent and -independent pathways for hematopoietic transformation. Blood. 2005 Jul 01; 106(1):328-37. Chen J, Williams IR, Lee BH, Duclos N, Huntly BJ, Donoghue DJ, Gilliland DG. PMID: 15784730; PMCID: PMC1895117.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    76. Constitutive activation of the shh-ptc1 pathway by a patched1 mutation identified in BCC. Oncogene. 2005 Jan 27; 24(5):902-15. Barnes EA, Heidtman KJ, Donoghue DJ. PMID: 15592520.
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    77. Campylobacter susceptibility to ciprofloxacin and corresponding fluoroquinolone concentrations within the gastrointestinal tracts of chickens. J Appl Microbiol. 2005; 99(5):1043-50. Farnell MB, Donoghue AM, Cole K, Reyes-Herrera I, Blore PJ, Donoghue DJ. PMID: 16238734.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCellsPHPublic Health
    78. Effects of aeration and storage temperature on Campylobacter concentrations in poultry semen. Poult Sci. 2004 Oct; 83(10):1734-8. Cole K, Donoghue AM, Blore PJ, Holliman JS, Cox NA, Musgrove MT, Donoghue DJ. PMID: 15510561.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    79. Detection of Campylobacter or Salmonella in turkey semen and the ability of poultry semen extenders to reduce their concentrations. Poult Sci. 2004 Oct; 83(10):1728-33. Donoghue AM, Blore PJ, Cole K, Loskutoff NM, Donoghue DJ. PMID: 15510560.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    80. Isolation and prevalence of Campylobacter in the reproductive tracts and semen of commercial turkeys. Avian Dis. 2004 Sep; 48(3):625-30. Cole K, Donoghue AM, Blore PJ, Donoghue DJ. PMID: 15529985.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    81. Comparison of a bioassay and a liquid chromatography-fluorescence-mass spectrometry(n) method for the detection of incurred enrofloxacin residues in chicken tissues. Poult Sci. 2004 May; 83(5):830-4. Schneider MJ, Donoghue DJ. PMID: 15141843.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCellsPHPublic Health
    82. The cytoplasmic tyrosine kinase Pyk2 as a novel effector of fibroblast growth factor receptor 3 activation. J Biol Chem. 2004 Jul 02; 279(27):28450-7. Meyer AN, Gastwirt RF, Schlaepfer DD, Donoghue DJ. PMID: 15105428.
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    83. Approach for selection of individual enteric bacteria for competitive exclusion in turkey poults. Poult Sci. 2003 Sep; 82(9):1378-82. Bielke LR, Elwood AL, Donoghue DJ, Donoghue AM, Newberry LA, Neighbor NK, Hargis BM. PMID: 12967248.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    84. Spy1 interacts with p27Kip1 to allow G1/S progression. Mol Biol Cell. 2003 Sep; 14(9):3664-74. Porter LA, Kong-Beltran M, Donoghue DJ. PMID: 12972555; PMCID: PMC196558.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    85. Comparison between a bioassay and liquid chromatography-fluorescence-mass spectrometry(n) for the determination of incurred enrofloxacin in whole eggs. J AOAC Int. 2003 Jul-Aug; 86(4):669-74. Donoghue DJ, Schneider MJ. PMID: 14509422.
      View in: PubMed   Mentions: 1     Fields:    Translation:CellsPHPublic Health
    86. Field testing the influence of sperm competition based on sperm mobility in breeder turkey toms. Br Poult Sci. 2003 Jul; 44(3):498-504. Donoghue AM, Kirby JD, Froman DP, Lerner SP, Crouch AN, King LM, Donoghue DJ, Sonstegard TS. PMID: 12964635.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    87. Human Spy1 promotes survival of mammalian cells following DNA damage. Cancer Res. 2003 Jul 01; 63(13):3701-7. Barnes EA, Porter LA, Lenormand JL, Dellinger RW, Donoghue DJ. PMID: 12839962.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    88. Antibiotic residues in poultry tissues and eggs: human health concerns? Poult Sci. 2003 Apr; 82(4):618-21. Donoghue DJ. PMID: 12710482.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsPHPublic Health
    89. Cyclin B1 and CDK1: nuclear localization and upstream regulators. Prog Cell Cycle Res. 2003; 5:335-47. Porter LA, Donoghue DJ. PMID: 14593728.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimalsCells
    90. Multiresidue analysis of fluoroquinolone antibiotics in chicken tissue using liquid chromatography-fluorescence-multiple mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Nov 15; 780(1):83-92. Schneider MJ, Donoghue DJ. PMID: 12383483.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsPHPublic Health
    91. Initial activation of cyclin-B1-cdc2 kinase requires phosphorylation of cyclin B1. EMBO Rep. 2002 Jun; 3(6):551-6. Peter M, Le Peuch C, Labbé JC, Meyer AN, Donoghue DJ, Dorée M. PMID: 12034754; PMCID: PMC1084145.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    92. Human Speedy: a novel cell cycle regulator that enhances proliferation through activation of Cdk2. J Cell Biol. 2002 Apr 29; 157(3):357-66. Porter LA, Dellinger RW, Tynan JA, Barnes EA, Kong M, Lenormand JL, Donoghue DJ. PMID: 11980914; PMCID: PMC2173287.
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    93. Interaction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation. J Biol Chem. 2002 May 03; 277(18):15962-70. Kong M, Wang CS, Donoghue DJ. PMID: 11827956.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    94. Analysis of pesticide residues in eggs by direct sample introduction/gas chromatography/tandem mass spectrometry. J Agric Food Chem. 2001 Oct; 49(10):4589-96. Lehotay SJ, Lightfield AR, Harman-Fetcho JA, Donoghue DJ. PMID: 11599993.
      View in: PubMed   Mentions: 6     Fields:    Translation:CellsPHPublic Health
    95. Patched1 interacts with cyclin B1 to regulate cell cycle progression. EMBO J. 2001 May 01; 20(9):2214-23. Barnes EA, Kong M, Ollendorff V, Donoghue DJ. PMID: 11331587; PMCID: PMC125436.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    96. Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activation. Mol Biol Cell. 2001 Apr; 12(4):931-42. Hart KC, Robertson SC, Donoghue DJ. PMID: 11294897; PMCID: PMC32277.
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    97. Determination of total 14C residues of sarafloxacin in eggs of laying hens. J Agric Food Chem. 2000 Dec; 48(12):6409-11. Chu PS, Donoghue DJ, Shaikh B. PMID: 11141293.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsPHPublic Health
    98. Imaging residue transfer into egg yolks. J Agric Food Chem. 2000 Dec; 48(12):6428-30. Donoghue DJ, Myers K. PMID: 11141297.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsPHPublic Health
    99. Determination of organochlorine and organophosphorus pesticide residues in eggs using a solid phase extraction cleanup. J Agric Food Chem. 2000 Dec; 48(12):6412-5. Schenck FJ, Donoghue DJ. PMID: 11141294.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsPHPublic Health
    100. Multiresidue determination of fluoroquinolones in eggs. J AOAC Int. 2000 Nov-Dec; 83(6):1306-12. Schneider MJ, Donoghue DJ. PMID: 11128131.
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    101. Distinct missense mutations of the FGFR3 lys650 codon modulate receptor kinase activation and the severity of the skeletal dysplasia phenotype. Am J Hum Genet. 2000 Dec; 67(6):1411-21. Bellus GA, Spector EB, Speiser PW, Weaver CA, Garber AT, Bryke CR, Israel J, Rosengren SS, Webster MK, Donoghue DJ, Francomano CA. PMID: 11055896; PMCID: PMC1287918.
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    102. Rotational coupling of the transmembrane and kinase domains of the Neu receptor tyrosine kinase. Mol Biol Cell. 2000 Oct; 11(10):3589-99. Bell CA, Tynan JA, Hart KC, Meyer AN, Robertson SC, Donoghue DJ. PMID: 11029057; PMCID: PMC15017.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    103. Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4. Oncogene. 2000 Jul 06; 19(29):3309-20. Hart KC, Robertson SC, Kanemitsu MY, Meyer AN, Tynan JA, Donoghue DJ. PMID: 10918587.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    104. RTK mutations and human syndromeswhen good receptors turn bad. Trends Genet. 2000 Jun; 16(6):265-71. Robertson SC, Tynan JA, Donoghue DJ. PMID: 10827454.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    105. Activation of H-ras61L-specific signaling pathways does not require posttranslational processing of H-ras. Exp Cell Res. 2000 May 25; 257(1):89-100. Hart KC, Robertson SC, Donoghue DJ. PMID: 10854057.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    106. Food safety implication: certain antibiotics may rapidly contaminate egg albumen during the process of its formation. Br Poult Sci. 2000 May; 41(2):174-7. Donoghue DJ, Hairston H. PMID: 10890213.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCellsPHPublic Health
    107. Supercritical fluid extraction of atrazine and other triazine herbicides from fortified and incurred eggs. J Agric Food Chem. 2000 May; 48(5):1668-72. Pensabene JW, Fiddler W, Donoghue DJ. PMID: 10820076.
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    108. Cyclin F regulates the nuclear localization of cyclin B1 through a cyclin-cyclin interaction. EMBO J. 2000 Mar 15; 19(6):1378-88. Kong M, Barnes EA, Ollendorff V, Donoghue DJ. PMID: 10716937; PMCID: PMC305678.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    109. Isolation of chloramphenicol from whole eggs by supercritical fluid extraction with in-line collection. J AOAC Int. 1999 Nov-Dec; 82(6):1334-9. Pensabene JW, Fiddler W, Donoghue DJ. PMID: 10589485.
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    110. Determination of sarafloxacin residues in fortified and incurred eggs using on-line microdialysis and HPLC/programmable fluorescence detection. J Agric Food Chem. 1999 Apr; 47(4):1563-7. Maxwell RJ, Cohen E, Donoghue DJ. PMID: 10564017.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsPHPublic Health
    111. Speedy: a novel cell cycle regulator of the G2/M transition. EMBO J. 1999 Apr 01; 18(7):1869-77. Lenormand JL, Dellinger RW, Knudsen KE, Subramani S, Donoghue DJ. PMID: 10202150; PMCID: PMC1171272.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    112. Automated multi-residue isolation of fluoroquinolone antimicrobials from fortified and incurred chicken liver using on-line microdialysis and high-performance liquid chromatography with programmable fluorescence detection. J Chromatogr B Biomed Sci Appl. 1999 Mar 05; 724(1):137-45. Cohen E, Maxwell RJ, Donoghue DJ. PMID: 10202966.
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    113. A novel skeletal dysplasia with developmental delay and acanthosis nigricans is caused by a Lys650Met mutation in the fibroblast growth factor receptor 3 gene. Am J Hum Genet. 1999 Mar; 64(3):722-31. Tavormina PL, Bellus GA, Webster MK, Bamshad MJ, Fraley AE, McIntosh I, Szabo J, Jiang W, Jabs EW, Wilcox WR, Wasmuth JJ, Donoghue DJ, Thompson LM, Francomano CA. PMID: 10053006; PMCID: PMC1377789.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    114. Oxytetracycline transfer into chicken egg yolk or albumen. Poult Sci. 1999 Mar; 78(3):343-5. Donoghue DJ, Hairston H. PMID: 10090259.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsPHPublic Health
    115. Activating mutations in the extracellular domain of the fibroblast growth factor receptor 2 function by disruption of the disulfide bond in the third immunoglobulin-like domain. Proc Natl Acad Sci U S A. 1998 Apr 14; 95(8):4567-72. Robertson SC, Meyer AN, Hart KC, Galvin BD, Webster MK, Donoghue DJ. PMID: 9539778; PMCID: PMC22530.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    116. Constitutive activation of fibroblast growth factor receptor 3 by mutations responsible for the lethal skeletal dysplasia thanatophoric dysplasia type I. Cell Growth Differ. 1998 Jan; 9(1):71-8. d'Avis PY, Robertson SC, Meyer AN, Bardwell WM, Webster MK, Donoghue DJ. PMID: 9438390.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    117. The serine/threonine phosphatase PP5 interacts with CDC16 and CDC27, two tetratricopeptide repeat-containing subunits of the anaphase-promoting complex. J Biol Chem. 1997 Dec 19; 272(51):32011-8. Ollendorff V, Donoghue DJ. PMID: 9405394.
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    118. Modeling Drug Residue Uptake by Eggs: Evidence of a Consistent Daily Pattern of Contaminant Transfer into Developing Preovulatory Yolks. J Food Prot. 1997 Oct; 60(10):1251-1255. Donoghue DJ, Schenck FJ, Hairston H, Podhorniak LV. PMID: 31207720.
      View in: PubMed   Mentions: 2     Fields:    
    119. Effects of water- and lipid-soluble antioxidants on turkey sperm viability, membrane integrity, and motility during liquid storage. Poult Sci. 1997 Oct; 76(10):1440-5. Donoghue AM, Donoghue DJ. PMID: 9316122.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    120. Enhanced signaling and morphological transformation by a membrane-localized derivative of the fibroblast growth factor receptor 3 kinase domain. Mol Cell Biol. 1997 Oct; 17(10):5739-47. Webster MK, Donoghue DJ. PMID: 9315632; PMCID: PMC232422.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    121. Transmembrane domain sequence requirements for activation of the p185c-neu receptor tyrosine kinase. J Cell Biol. 1997 May 05; 137(3):619-31. Chen LI, Webster MK, Meyer AN, Donoghue DJ. PMID: 9151669; PMCID: PMC2139875.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    122. Phosphorylation makes cyclin (B)eeline for the nucleus. Trends Cell Biol. 1997 May; 7(5):181. Li J, Meyer AN, Donoghue DJ. PMID: 17708941.
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    123. FGFR activation in skeletal disorders: too much of a good thing. Trends Genet. 1997 May; 13(5):178-82. Webster MK, Donoghue DJ. PMID: 9154000.
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    124. Modeling drug residue uptake by eggs: yolks contain ampicillin residues even after drug withdrawal and nondetectability in the plasma. Poult Sci. 1997 Mar; 76(3):458-62. Donoghue DJ, Hairston H, Henderson M, McDonald M, Gaines S, Donoghue AM. PMID: 9068044.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsPHPublic Health
    125. Derivatives of activated H-ras lacking C-terminal lipid modifications retain transforming ability if targeted to the correct subcellular location. Oncogene. 1997 Feb 27; 14(8):945-53. Hart KC, Donoghue DJ. PMID: 9050994; PMCID: PMC7100284.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    126. Nuclear localization of cyclin B1 mediates its biological activity and is regulated by phosphorylation. Proc Natl Acad Sci U S A. 1997 Jan 21; 94(2):502-7. Li J, Meyer AN, Donoghue DJ. PMID: 9012813; PMCID: PMC19542.
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    127. Profound ligand-independent kinase activation of fibroblast growth factor receptor 3 by the activation loop mutation responsible for a lethal skeletal dysplasia, thanatophoric dysplasia type II. Mol Cell Biol. 1996 Aug; 16(8):4081-7. Webster MK, D'Avis PY, Robertson SC, Donoghue DJ. PMID: 8754806; PMCID: PMC231404.
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    128. Constitutive receptor activation by Crouzon syndrome mutations in fibroblast growth factor receptor (FGFR)2 and FGFR2/Neu chimeras. Proc Natl Acad Sci U S A. 1996 Jul 23; 93(15):7894-9. Galvin BD, Hart KC, Meyer AN, Webster MK, Donoghue DJ. PMID: 8755573; PMCID: PMC38845.
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    129. Identification of an autoinhibitory region in the activation loop of the Mos protein kinase. Mol Cell Biol. 1996 Jul; 16(7):3472-9. Robertson SC, Donoghue DJ. PMID: 8668163; PMCID: PMC231342.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    130. A new method for rapid determination of sperm concentration in turkey semen. Poult Sci. 1996 Jun; 75(6):785-9. Donoghue AM, Thistlethwaite D, Donoghue DJ, Kirby JD. PMID: 8737845.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    131. Modeling residue uptake by eggs. 1. Similar drug residue patterns in developing yolks following injection with ampicillin or oxytetracycline. Poult Sci. 1996 Mar; 75(3):321-8. Donoghue DJ, Hairston H, Gaines SA, Bartholomew MJ, Donoghue AM. PMID: 8778723.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsPHPublic Health
    132. Constitutive activation of fibroblast growth factor receptor 3 by the transmembrane domain point mutation found in achondroplasia. EMBO J. 1996 Feb 01; 15(3):520-7. Webster MK, Donoghue DJ. PMID: 8599935; PMCID: PMC449970.
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    133. Effect of semen storage on the number of spermatozoa in the perivitelline layer of laid turkey eggs. J Reprod Fertil. 1995 Nov; 105(2):221-5. Donoghue AM, Bakst MR, Holsberger DR, Donoghue DJ. PMID: 8568764.
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    134. Requirement for phosphorylation of cyclin B1 for Xenopus oocyte maturation. Mol Biol Cell. 1995 Sep; 6(9):1111-24. Li J, Meyer AN, Donoghue DJ. PMID: 8534910; PMCID: PMC301271.
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    135. Viability assessment of turkey sperm using fluorescent staining and flow cytometry. Poult Sci. 1995 Jul; 74(7):1191-200. Donoghue AM, Garner DL, Donoghue DJ, Johnson LA. PMID: 7479495.
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    136. Structure and function of the platelet-derived growth factor family and their receptors. Genet Eng (N Y). 1995; 17:181-208. Hart KC, Galvin BD, Donoghue DJ. PMID: 7779512.
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    137. The v-sis oncoprotein loses transforming activity when targeted to the early Golgi complex. J Cell Biol. 1994 Dec; 127(6 Pt 2):1843-57. Hart KC, Xu YF, Meyer AN, Lee BA, Donoghue DJ. PMID: 7806564; PMCID: PMC2120273.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    138. Cellular transformation by a transmembrane peptide: structural requirements for the bovine papillomavirus E5 oncoprotein. Proc Natl Acad Sci U S A. 1994 May 24; 91(11):4634-8. Meyer AN, Xu YF, Webster MK, Smith AE, Donoghue DJ. PMID: 8197111; PMCID: PMC43842.
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    139. Mutants at Ser277 of Xenopus cdc2 protein kinase induce oocyte maturation in the absence of the positive regulatory phosphorylation site Thr161. Mol Biol Cell. 1994 May; 5(5):587-96. Pickham KM, Donoghue DJ. PMID: 7919539; PMCID: PMC301070.
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    140. Incurred Arsenic Residues in Chicken Eggs. J Food Prot. 1994 Mar; 57(3):218-223. Donoghue DJ, Hairston H, Cope CV, Bartholomew MJ, Wagner DD. PMID: 31113070.
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    141. The v-sis protein retains biological activity as a type II membrane protein when anchored by various signal-anchor domains, including the hydrophobic domain of the bovine papilloma virus E5 oncoprotein. J Cell Biol. 1993 Nov; 123(3):549-60. Xu YF, Meyer AN, Webster MK, Lee BA, Donoghue DJ. PMID: 8227125; PMCID: PMC2200122.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    142. Alanine mutagenesis of conserved residues in the platelet-derived growth factor family: identification of residues necessary for dimerization and transformation. Oncogene. 1993 Mar; 8(3):533-41. Maher DW, Strawn LM, Donoghue DJ. PMID: 8437840.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    143. Ontogeny of pituitary growth hormone and growth hormone mRNA in the chicken. Proc Soc Exp Biol Med. 1993 Jan; 202(1):109-13. McCann-Levorse LM, Radecki SV, Donoghue DJ, Malamed S, Foster DN, Scanes CG. PMID: 8424091.
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    144. Intracellular retention of membrane-anchored v-sis protein abrogates autocrine signal transduction. J Cell Biol. 1992 Sep; 118(5):1057-70. Lee BA, Donoghue DJ. PMID: 1324943; PMCID: PMC2289590.
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    145. Requirement of mosXe protein kinase for meiotic maturation of Xenopus oocytes induced by a cdc2 mutant lacking regulatory phosphorylation sites. Mol Cell Biol. 1992 Jul; 12(7):3192-203. Pickham KM, Meyer AN, Li J, Donoghue DJ. PMID: 1377775; PMCID: PMC364534.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    146. Phosphorylation of conserved serine residues does not regulate the ability of mosxe protein kinase to induce oocyte maturation or function as cytostatic factor. J Cell Biol. 1992 Feb; 116(3):725-35. Freeman RS, Meyer AN, Li J, Donoghue DJ. PMID: 1530949; PMCID: PMC2289311.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    147. cdc25+ encodes a protein phosphatase that dephosphorylates p34cdc2. Mol Biol Cell. 1992 Jan; 3(1):73-84. Lee MS, Ogg S, Xu M, Parker LL, Donoghue DJ, Maller JL, Piwnica-Worms H. PMID: 1312880; PMCID: PMC275503.
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    148. Progression from meiosis I to meiosis II in Xenopus oocytes requires de novo translation of the mosxe protooncogene. Proc Natl Acad Sci U S A. 1991 Jul 01; 88(13):5794-8. Kanki JP, Donoghue DJ. PMID: 1648231; PMCID: PMC51964.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    149. Membrane-anchored form of v-sis/PDGF-B induces mitogenesis without detectable PDGF receptor autophosphorylation. J Cell Biol. 1991 Apr; 113(2):361-70. Lee BA, Donoghue DJ. PMID: 1849139; PMCID: PMC2288947.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    150. Protein kinases and protooncogenes: biochemical regulators of the eukaryotic cell cycle. Biochemistry. 1991 Mar 05; 30(9):2293-302. Freeman RS, Donoghue DJ. PMID: 2001361.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    151. Meiotic induction by Xenopus cyclin B is accelerated by coexpression with mosXe. Mol Cell Biol. 1991 Mar; 11(3):1713-7. Freeman RS, Ballantyne SM, Donoghue DJ. PMID: 1825350; PMCID: PMC369479.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    152. Magnesium-aspartate-hydrochloride reduces weight loss in heat-stressed laying hens. Poult Sci. 1990 Nov; 69(11):1862-8. Donoghue DJ, Krueger WF, Donoghue AM, Byrd JA, Ali DH, el Halawani ME. PMID: 2087447.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    153. Effect of biosynthetic chicken growth hormone on egg production in White Leghorn hens. Poult Sci. 1990 Oct; 69(10):1818-21. Donoghue DJ, Campbell RM, Scanes CG. PMID: 2263560.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    154. Effects of the v-mos oncogene on Xenopus development: meiotic induction in oocytes and mitotic arrest in cleaving embryos. J Cell Biol. 1990 Aug; 111(2):533-41. Freeman RS, Kanki JP, Ballantyne SM, Pickham KM, Donoghue DJ. PMID: 2143197; PMCID: PMC2116195.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    155. Transforming mutant v-mos protein kinases that are deficient in in vitro autophosphorylation. Mol Cell Biol. 1989 Sep; 9(9):4087-90. Freeman RS, Donoghue DJ. PMID: 2528689; PMCID: PMC362478.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    156. Xenopus homolog of the mos protooncogene transforms mammalian fibroblasts and induces maturation of Xenopus oocytes. Proc Natl Acad Sci U S A. 1989 Aug; 86(15):5805-9. Freeman RS, Pickham KM, Kanki JP, Lee BA, Pena SV, Donoghue DJ. PMID: 2527365; PMCID: PMC297719.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    157. Structure and function of platelet-derived growth factor (PDGF) and related proteins. Biochim Biophys Acta. 1989 Jul 28; 989(1):1-10. Hannink M, Donoghue DJ. PMID: 2546599.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    158. The alternatively spliced exon of the platelet-derived growth factor A chain encodes a nuclear targeting signal. Mol Cell Biol. 1989 May; 9(5):2251-3. Maher DW, Lee BA, Donoghue DJ. PMID: 2747650; PMCID: PMC363024.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    159. Autocrine stimulation by the v-sis gene product requires a ligand-receptor interaction at the cell surface. J Cell Biol. 1988 Jul; 107(1):287-98. Hannink M, Donoghue DJ. PMID: 2455725; PMCID: PMC2115171.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    160. The histidine-221 to tyrosine substitution in v-mos abolishes its biological function and its protein kinase activity. Virology. 1988 May; 164(1):114-20. Singh B, Wittenberg C, Hannink M, Reed SI, Donoghue DJ, Arlinghaus RB. PMID: 2966489.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    161. Identification of nonessential disulfide bonds and altered conformations in the v-sis protein, a homolog of the B chain of platelet-derived growth factor. Mol Cell Biol. 1988 Mar; 8(3):1011-8. Sauer MK, Donoghue DJ. PMID: 2835654; PMCID: PMC363243.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    162. Identification of a signal for nuclear targeting in platelet-derived-growth-factor-related molecules. Mol Cell Biol. 1987 Oct; 7(10):3527-37. Lee BA, Maher DW, Hannink M, Donoghue DJ. PMID: 3316980; PMCID: PMC368005.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    163. Cell surface expression of membrane-anchored v-sis gene products: glycosylation is not required for cell surface transport. J Cell Biol. 1986 Dec; 103(6 Pt 1):2311-22. Hannink M, Donoghue DJ. PMID: 3536965; PMCID: PMC2114596.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    164. Deletions in the N-terminal coding region of the v-sis gene: determination of the minimal transforming region. J Virol. 1986 Aug; 59(2):292-300. Sauer MK, Hannink M, Donoghue DJ. PMID: 3525855; PMCID: PMC253078.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    165. Deletions in the C-terminal coding region of the v-sis gene: dimerization is required for transformation. Mol Cell Biol. 1986 Apr; 6(4):1304-14. Hannink M, Sauer MK, Donoghue DJ. PMID: 3785165; PMCID: PMC367643.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    166. Lysine residue 121 in the proposed ATP-binding site of the v-mos protein is required for transformation. Proc Natl Acad Sci U S A. 1985 Dec; 82(23):7894-8. Hannink M, Donoghue DJ. PMID: 2999782; PMCID: PMC390876.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    167. Biologically active mutants with deletions in the v-mos oncogene assayed with retroviral vectors. Mol Cell Biol. 1985 Nov; 5(11):3131-8. Bold RJ, Donoghue DJ. PMID: 3018503; PMCID: PMC369128.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    168. Transmission of the polyoma virus middle T gene as the oncogene of a murine retrovirus. Nature. 1984 Apr 19-25; 308(5961):748-50. Donoghue DJ, Anderson C, Hunter T, Kaplan PL. PMID: 6325917.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    169. Demonstration of biological activity and nucleotide sequence of an in vitro synthesized clone of the Moloney murine sarcoma virus mos gene. J Virol. 1982 May; 42(2):538-46. Donoghue DJ. PMID: 7045395; PMCID: PMC256880.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    170. A generalized method of subcloning DNA fragments by restriction site reconstruction: application to sequencing the amino-terminal coding region of the transforming gene of Gazdar murine sarcoma virus. Nucleic Acids Res. 1982 Apr 24; 10(8):2549-64. Donoghue DJ, Hunter T. PMID: 6281735; PMCID: PMC320633.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
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