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    Shantanu Sinha

    TitleProfessor In Residence
    SchoolUniversity of California, San Diego
    DepartmentRadiology
    Address9500 Gilman Drive #0852
    CA La Jolla 92093
    Phone858-534-2004
    vCardDownload vCard

      Collapse Biography 
      Collapse Education and Training
      University of IllinoisPostdoc RA1984Physical Chemistry
      Indian Institute of SciencePostdoc1983Solid State Physics
      Indian Institute of SciencePh.D.1983Solid State Physics
      Indian Institute of TechnologyM.Sc.1977Physics
      Indian Institute of TechnologyB.Sc.1975Physics
      Collapse Awards and Honors
      AMSSM2000Best research paper award
      American Heart Association1995Laverna Titus Young Investigator
      NCERT, New Delhi1972 - 1983National Science Talent Scholarship

      Collapse Overview 

      Collapse Research 
      Collapse Research Activities and Funding
      In Vivo Imaging-Based Multiscale Modeling of Normal and Atrophied Human Lower Leg
      NIH R01AR053343Jul 15, 2006 - Jun 30, 2015
      Role: Principal Investigator
      IMAGE GUIDED THERAPY CENTER
      NIH U41RR019703Sep 29, 2005 - Jul 31, 2010
      Role: Co-Investigator
      Brain Tumor Therapy: Radio Surgery vs. MR-Guided Ablat;
      NIH R21CA094226Jun 1, 2004 - May 31, 2006
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Kinugasa R, Yamamura N, Sinha S, Takagi S. Influence of intramuscular fiber orientation on the Achilles tendon curvature using three-dimensional finite element modeling of contracting skeletal muscle. J Biomech. 2016 Oct 3; 49(14):3592-3595. PMID: 27663620.
        View in: PubMed
      2. Ugarte V, Sinha U, Malis V, Csapo R, Sinha S. 3D multimodal spatial fuzzy segmentation of intramuscular connective and adipose tissue from ultrashort TE MR images of calf muscle. Magn Reson Med. 2016 Feb 19. PMID: 26892499.
        View in: PubMed
      3. Csapo R, Malis V, Sinha U, Sinha S. Mapping of spatial and temporal heterogeneity of plantar flexor muscle activity during isometric contraction: correlation of velocity-encoded MRI with EMG. J Appl Physiol (1985). 2015 Sep 1; 119(5):558-68. PMID: 26112239.
        View in: PubMed
      4. Sinha U, Malis V, Csapo R, Moghadasi A, Kinugasa R, Sinha S. Age-related differences in strain rate tensor of the medial gastrocnemius muscle during passive plantarflexion and active isometric contraction using velocity encoded MR imaging: Potential index of lateral force transmission. Magn Reson Med. 2015 May; 73(5):1852-63. PMID: 25046255.
        View in: PubMed
      5. Raj Rajasekaran M, Sinha S, Seo Y, Salehi M, Bhargava V, Mittal RK. Myoarchitectural and functional alterations in rabbit external anal sphincter muscle following experimental surgical trauma. Am J Physiol Gastrointest Liver Physiol. 2014 Aug 15; 307(4):G445-51. PMID: 24994856.
        View in: PubMed
      6. Csapo R, Malis V, Sinha U, Du J, Sinha S. Age-associated differences in triceps surae muscle composition and strength - an MRI-based cross-sectional comparison of contractile, adipose and connective tissue. BMC Musculoskelet Disord. 2014; 15(1):209. PMID: 24939372.
        View in: PubMed
      7. Sinha U, Csapo R, Malis V, Xue Y, Sinha S. Age-related differences in diffusion tensor indices and fiber architecture in the medial and lateral gastrocnemius. J Magn Reson Imaging. 2015 Apr; 41(4):941-53. PMID: 24771672.
        View in: PubMed
      8. Mittal RK, Bhargava V, Sheean G, Ledgerwood M, Sinha S. Purse-string morphology of external anal sphincter revealed by novel imaging techniques. Am J Physiol Gastrointest Liver Physiol. 2014 Mar; 306(6):G505-14. PMID: 24458022.
        View in: PubMed
      9. Kinugasa R, Oda T, Komatsu T, Edgerton VR, Sinha S. Interaponeurosis shear strain modulates behavior of myotendinous junction of the human triceps surae. Physiol Rep. 2013 Nov; 1(6):e00147. PMID: 24400149.
        View in: PubMed
      10. Csapo R, Hodgson J, Kinugasa R, Edgerton VR, Sinha S. Ankle morphology amplifies calcaneus movement relative to triceps surae muscle shortening. J Appl Physiol (1985). 2013 Aug 15; 115(4):468-73. PMID: 23743400.
        View in: PubMed
      11. Sinha S, Shin DD, Hodgson JA, Kinugasa R, Edgerton VR. Computer-controlled, MR-compatible foot-pedal device to study dynamics of the muscle tendon complex under isometric, concentric, and eccentric contractions. J Magn Reson Imaging. 2012 Aug; 36(2):498-504. PMID: 22392816.
        View in: PubMed
      12. Hodgson JA, Chi SW, Yang JP, Chen JS, Edgerton VR, Sinha S. Finite element modeling of passive material influence on the deformation and force output of skeletal muscle. J Mech Behav Biomed Mater. 2012 May; 9:163-83. PMID: 22498294.
        View in: PubMed
      13. Kinugasa R, Hodgson JA, Edgerton VR, Sinha S. Asymmetric deformation of contracting human gastrocnemius muscle. J Appl Physiol (1985). 2012 Feb; 112(3):463-70. PMID: 22134691.
        View in: PubMed
      14. Kinugasa R, Kawakami Y, Sinha S, Fukunaga T. Unique spatial distribution of in vivo human muscle activation. Exp Physiol. 2011 Sep; 96(9):938-48. PMID: 21666032.
        View in: PubMed
      15. Sinha S, Sinha U. Reproducibility analysis of diffusion tensor indices and fiber architecture of human calf muscles in vivo at 1.5 Tesla in neutral and plantarflexed ankle positions at rest. J Magn Reson Imaging. 2011 Jul; 34(1):107-19. PMID: 21608064.
        View in: PubMed
      16. Sinha U, Sinha S, Hodgson JA, Edgerton RV. Human soleus muscle architecture at different ankle joint angles from magnetic resonance diffusion tensor imaging. J Appl Physiol (1985). 2011 Mar; 110(3):807-19. PMID: 21164150.
        View in: PubMed
      17. Kinugasa R, Hodgson JA, Edgerton VR, Shin DD, Sinha S. Reduction in tendon elasticity from unloading is unrelated to its hypertrophy. J Appl Physiol (1985). 2010 Sep; 109(3):870-7. PMID: 20616227.
        View in: PubMed
      18. Chi SW, Hodgson J, Chen JS, Reggie Edgerton V, Shin DD, Roiz RA, Sinha S. Finite element modeling reveals complex strain mechanics in the aponeuroses of contracting skeletal muscle. J Biomech. 2010 May 7; 43(7):1243-50. PMID: 20189180.
        View in: PubMed
      19. Shin DD, Hodgson JA, Edgerton VR, Sinha S. In vivo intramuscular fascicle-aponeuroses dynamics of the human medial gastrocnemius during plantarflexion and dorsiflexion of the foot. J Appl Physiol (1985). 2009 Oct; 107(4):1276-84. PMID: 19608924.
        View in: PubMed
      20. Sinha S, Sinha U. Recent advances in breast MRI and MRS. NMR Biomed. 2009 Jan; 22(1):3-16. PMID: 18654998.
        View in: PubMed
      21. Shin D, Finni T, Ahn S, Hodgson JA, Lee HD, Edgerton VR, Sinha S. In vivo estimation and repeatability of force-length relationship and stiffness of the human achilles tendon using phase contrast MRI. J Magn Reson Imaging. 2008 Oct; 28(4):1039-45. PMID: 18821605.
        View in: PubMed
      22. Kinugasa R, Shin D, Yamauchi J, Mishra C, Hodgson JA, Edgerton VR, Sinha S. Phase-contrast MRI reveals mechanical behavior of superficial and deep aponeuroses in human medial gastrocnemius during isometric contraction. J Appl Physiol (1985). 2008 Oct; 105(4):1312-20. PMID: 18703759.
        View in: PubMed
      23. Shin D, Finni T, Ahn S, Hodgson JA, Lee HD, Edgerton VR, Sinha S. Effect of chronic unloading and rehabilitation on human Achilles tendon properties: a velocity-encoded phase-contrast MRI study. J Appl Physiol (1985). 2008 Oct; 105(4):1179-86. PMID: 18687975.
        View in: PubMed
      24. Wen H, Dou Z, Finni T, Havu M, Kang Z, Cheng S, Sipilä S, Sinha S, Usenius JP, Cheng S. Thigh muscle function in stroke patients revealed by velocity-encoded cine phase-contrast magnetic resonance imaging. Muscle Nerve. 2008 Jun; 37(6):736-44. PMID: 18335468.
        View in: PubMed
      25. Finni T, Havu M, Sinha S, Usenius JP, Cheng S. Mechanical behavior of the quadriceps femoris muscle tendon unit during low-load contractions. J Appl Physiol (1985). 2008 May; 104(5):1320-8. PMID: 18339890.
        View in: PubMed
      26. Ahn S, Shin D, Tateshima S, Tanishita K, Vinuela F, Sinha S. Fluid-induced wall shear stress in anthropomorphic brain aneurysm models: MR phase-contrast study at 3 T. J Magn Reson Imaging. 2007 Jun; 25(6):1120-30. PMID: 17520716.
        View in: PubMed
      27. Sinha S, Sinha U, Edgerton VR. In vivo diffusion tensor imaging of the human calf muscle. J Magn Reson Imaging. 2006 Jul; 24(1):182-90. PMID: 16729262.
        View in: PubMed
      28. Hodgson JA, Finni T, Lai AM, Edgerton VR, Sinha S. Influence of structure on the tissue dynamics of the human soleus muscle observed in MRI studies during isometric contractions. J Morphol. 2006 May; 267(5):584-601. PMID: 16453292.
        View in: PubMed
      29. Vogel-Claussen J, Finn JP, Gomes AS, Hundley GW, Jerosch-Herold M, Pearson G, Sinha S, Lima JA, Bluemke DA. Left ventricular papillary muscle mass: relationship to left ventricular mass and volumes by magnetic resonance imaging. J Comput Assist Tomogr. 2006 May-Jun; 30(3):426-32. PMID: 16778617.
        View in: PubMed
      30. Grinstead JW, Sinha S, Tateshima S, Nien YL, Vinuela F. Visualization and quantification of flow and velocity fields in intracranial arteriovenous malformations using phase-contrast MR angiography. AJR Am J Roentgenol. 2006 Feb; 186(2):553-5. PMID: 16423967.
        View in: PubMed
      31. Lee HD, Finni T, Hodgson JA, Lai AM, Edgerton VR, Sinha S. Soleus aponeurosis strain distribution following chronic unloading in humans: an in vivo MR phase-contrast study. J Appl Physiol (1985). 2006 Jun; 100(6):2004-11. PMID: 16424072.
        View in: PubMed
      32. Finni T, Hodgson JA, Lai AM, Edgerton VR, Sinha S. Muscle synergism during isometric plantarflexion in achilles tendon rupture patients and in normal subjects revealed by velocity-encoded cine phase-contrast MRI. Clin Biomech (Bristol, Avon). 2006 Jan; 21(1):67-74. PMID: 16194588.
        View in: PubMed
      33. Bhidayasiri R, Bronstein JM, Sinha S, Krahl SE, Ahn S, Behnke EJ, Cohen MS, Frysinger R, Shellock FG. Bilateral neurostimulation systems used for deep brain stimulation: in vitro study of MRI-related heating at 1.5 T and implications for clinical imaging of the brain. Magn Reson Imaging. 2005 May; 23(4):549-55. PMID: 15919600.
        View in: PubMed
      34. Sinha S, Hodgson JA, Finni T, Lai AM, Grinstead J, Edgerton VR. Muscle kinematics during isometric contraction: development of phase contrast and spin tag techniques to study healthy and atrophied muscles. J Magn Reson Imaging. 2004 Dec; 20(6):1008-19. PMID: 15558560.
        View in: PubMed
      35. Sinha S, Sinha U. In vivo diffusion tensor imaging of the human prostate. Magn Reson Med. 2004 Sep; 52(3):530-7. PMID: 15334571.
        View in: PubMed
      36. Finni T, Hodgson JA, Lai AM, Edgerton VR, Sinha S. Mapping of movement in the isometrically contracting human soleus muscle reveals details of its structural and functional complexity. J Appl Physiol (1985). 2003 Nov; 95(5):2128-33. PMID: 12857769.
        View in: PubMed
      37. Finni T, Hodgson JA, Lai AM, Edgerton VR, Sinha S. Nonuniform strain of human soleus aponeurosis-tendon complex during submaximal voluntary contractions in vivo. J Appl Physiol (1985). 2003 Aug; 95(2):829-37. PMID: 12716873.
        View in: PubMed
      38. Sinha S, Sinha U. Functional magnetic resonance of human breast tumors: diffusion and perfusion imaging. Ann N Y Acad Sci. 2002 Dec; 980:95-115. PMID: 12594084.
        View in: PubMed
      39. Sinha S, Lucas-Quesada FA, Sinha U, DeBruhl N, Bassett LW. In vivo diffusion-weighted MRI of the breast: potential for lesion characterization. J Magn Reson Imaging. 2002 Jun; 15(6):693-704. PMID: 12112520.
        View in: PubMed
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