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TAX1BP3 Is a SUMOylated Nucleocytoplasmic Shuttling Protein and Protects Against Vascular Neointimal Hyperplasia. Circulation. 2025 Oct 14; 152(15):1087-1108.
Yang H, Zhong Y, Guo W, Guo W, Chen B, Lin Z, Zhang Q, Zou R, Cao X, Li F, Feng W, Yan J, Zeng Z, Wang W, Ouyang K, Xu X, Fan X, Fang X, Ai S, Liu C. PMID: 40955569.
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Loss of GATAD1 in cardiomyocyte does not cause cardiomyopathy in mice. J Mol Histol. 2024 Dec 06; 56(1):33.
Pang J, Zhu S, Shyy M, Duong J, Tran T, Sanchez-Garcia E, Chen C, Gu Y, Fang X. PMID: 39641830; PMCID: PMC12054008.
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1 Fields:
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AnimalsCells
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Kindlin-2 Phase Separation in Response to Flow Controls Vascular Stability. Circ Res. 2024 Dec 06; 135(12):1141-1160.
Ma N, Wu F, Liu J, Wu Z, Wang L, Li B, Liu Y, Dong X, Hu J, Fang X, Zhang H, Ai D, Zhou J, Wang X. PMID: 39492718.
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HFpEF's Fuel Flaw: Impaired Fatty Acid Oxidation Stalls Mitophagy. Circ Res. 2024 Oct 25; 135(10):1018-1020.
Fang X, Gustafsson ÅB. PMID: 39446882; PMCID: PMC11507057.
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The essential role of MED27 in stabilizing the mediator complex for cardiac development and function. Life Sci. 2024 Nov 01; 356:123020.
Zhu S, Chen Z, Liu C, Duong J, Tran T, Liang Z, Fang X, Ouyang K. PMID: 39209248.
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2 Fields:
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AnimalsCells
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Dietary linoleic acid supplementation fails to rescue established cardiomyopathy in Barth syndrome. J Mol Cell Cardiol Plus. 2024 Jun; 8.
Zhu S, Pang J, Nguyen A, Huynh H, Lee S, Gu Y, Vaz FM, Fang X. PMID: 38974772; PMCID: PMC11225933.
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1
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Temporal Effects of Safflower Oil Diet-Based Linoleic Acid Supplementation on Barth Syndrome Cardiomyopathy. Circulation. 2024 03 05; 149(10):790-793.
Zhu S, Pang J, Nguyen A, Tan C, Tso A, Huynh T, Gu Y, Gustafsson AB, Vaz FM, Evans SM, Fang X. PMID: 38437482; PMCID: PMC10914323.
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Humans
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DELE1 is protective for mitochondrial cardiomyopathy. J Mol Cell Cardiol. 2023 02; 175:44-48.
Huynh H, Zhu S, Lee S, Bao Y, Pang J, Nguyen A, Gu Y, Chen C, Ouyang K, Evans SM, Fang X. PMID: 36539111; PMCID: PMC10387237.
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8 Fields:
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HumansCells
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Loss of IP3 Receptor-Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function. J Immunol. 2017 07 15; 199(2):570-580.
Tang H, Wang H, Lin Q, Fan F, Zhang F, Peng X, Fang X, Liu J, Ouyang K. PMID: 28615414.
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25 Fields:
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AnimalsCells
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Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle. J Cell Biol. 2017 07 03; 216(7):1915-1924.
Stroud MJ, Feng W, Zhang J, Veevers J, Fang X, Gerace L, Chen J. PMID: 28533284; PMCID: PMC5496623.
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41 Fields:
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IP3 receptors regulate vascular smooth muscle contractility and hypertension. JCI Insight. 2016 Oct 20; 1(17):e89402.
Lin Q, Zhao G, Fang X, Peng X, Tang H, Wang H, Jing R, Liu J, Lederer WJ, Chen J, Ouyang K. PMID: 27777977; PMCID: PMC5070959.
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43 Fields:
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AnimalsCells
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Activation of PPAR-δ induces microRNA-100 and decreases the uptake of very low-density lipoprotein in endothelial cells. Br J Pharmacol. 2015 Aug; 172(15):3728-36.
Fang X, Fang L, Liu A, Wang X, Zhao B, Wang N. PMID: 25857370; PMCID: PMC4523331.
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10 Fields:
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HumansCells
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Tumor-derived microRNA-494 promotes angiogenesis in non-small cell lung cancer. Angiogenesis. 2015 Jul; 18(3):373-82.
Mao G, Liu Y, Fang X, Liu Y, Fang L, Lin L, Liu X, Wang N. PMID: 26040900.
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97 Fields:
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HumansAnimalsCells
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Normalization of Naxos plakoglobin levels restores cardiac function in mice. J Clin Invest. 2015 Apr; 125(4):1708-12.
Zhang Z, Stroud MJ, Zhang J, Fang X, Ouyang K, Kimura K, Mu Y, Dalton ND, Gu Y, Bradford WH, Peterson KL, Cheng H, Zhou X, Chen J. PMID: 25705887; PMCID: PMC4396479.
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25 Fields:
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HumansAnimalsCells
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Epigallocatechin-3-O-gallate, a green tea polyphenol, induces expression of pim-1 kinase via PPARγ in human vascular endothelial cells. Cardiovasc Toxicol. 2013 Dec; 13(4):391-5.
Liu Y, Zhao B, Mao G, Fang X, Liu Y, Huang Y, Wang N. PMID: 23990052.
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8 Fields:
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HumansCells
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Shear stress activation of nuclear receptor PXR in endothelial detoxification. Proc Natl Acad Sci U S A. 2013 Aug 06; 110(32):13174-9.
Wang X, Fang X, Zhou J, Chen Z, Zhao B, Xiao L, Liu A, Li YS, Shyy JY, Guan Y, Chien S, Wang N. PMID: 23878263; PMCID: PMC3740860.
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28 Fields:
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HumansAnimalsCells
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Response to overexpression of 5-hydroxytryptamine 2B receptor gene in pulmonary hypertension: still a long way to understand its transcriptional regulation. Hypertension. 2013 Apr; 61(4):e30.
Liu Y, Tian XY, Mao G, Fang X, Fung ML, Shyy JY, Huang Y, Wang N. PMID: 23607134.
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Animals
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Peroxisome proliferator-activated receptor-γ ameliorates pulmonary arterial hypertension by inhibiting 5-hydroxytryptamine 2B receptor. Hypertension. 2012 Dec; 60(6):1471-8.
Liu Y, Tian XY, Mao G, Fang X, Fung ML, Shyy JY, Huang Y, Wang N. PMID: 23108648.
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28 Fields:
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AnimalsCells
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Role of peroxisome proliferator-activated receptor-γ in atherosclerosis: an update. Circ J. 2011; 75(3):528-35.
Wang N, Yin R, Liu Y, Mao G, Xi F. PMID: 21325726.
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23 Fields:
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HumansAnimals