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Weg Ongkeko

TitleAssociate Adjunct Professor
InstitutionUniversity of California San Diego
DepartmentSurgery
Address9500 Gilman Drive #9151
La Jolla CA 92093
Phone858-552-8585
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Li WT, Zheng H, Nguyen V, Wang-Rodriguez J, Ongkeko WM. Functional Genomics Profiling of Bladder Urothelial Carcinoma MicroRNAome as a Potential Biomarker. Neoplasia. 2018 Apr; 20(4):364-373. PMID: 29544183.
      View in: PubMed
    2. Krishnan AR, Qu Y, Li PX, Zou AE, Califano JA, Wang-Rodriguez J, Ongkeko WM. Computational methods reveal novel functionalities of PIWI-interacting RNAs in human papillomavirus-induced head and neck squamous cell carcinoma. Oncotarget. 2018 Jan 12; 9(4):4614-4624. PMID: 29435129.
      View in: PubMed
    3. Zheng H, Li P, Kwok JG, Korrapati A, Li WT, Qu Y, Wang XQ, Kisseleva T, Wang-Rodriguez J, Ongkeko WM. Alcohol and hepatitis virus-dysregulated lncRNAs as potential biomarkers for hepatocellular carcinoma. Oncotarget. 2018 Jan 02; 9(1):224-235. PMID: 29416609.
      View in: PubMed
    4. Krishnan AR, Zheng H, Kwok JG, Qu Y, Zou AE, Korrapati A, Li PX, Califano JA, Hovell MF, Wang-Rodriguez J, Ongkeko WM. A comprehensive study of smoking-specific microRNA alterations in head and neck squamous cell carcinoma. Oral Oncol. 2017 Sep; 72:56-64. PMID: 28797462.
      View in: PubMed
    5. Zheng H, Zou AE, Saad MA, Wang XQ, Kwok JG, Korrapati A, Li P, Kisseleva T, Wang-Rodriguez J, Ongkeko WM. Alcohol-dysregulated microRNAs in hepatitis B virus-related hepatocellular carcinoma. PLoS One. 2017; 12(5):e0178547. PMID: 28562643.
      View in: PubMed
    6. Krishnan AR, Korrapati A, Zou AE, Qu Y, Wang XQ, Califano JA, Wang-Rodriguez J, Lippman SM, Hovell MF, Ongkeko WM. Smoking status regulates a novel panel of PIWI-interacting RNAs in head and neck squamous cell carcinoma. Oral Oncol. 2017 Feb; 65:68-75. PMID: 28109471.
      View in: PubMed
    7. Zou AE, Zheng H, Saad MA, Rahimy M, Ku J, Kuo SZ, Honda TK, Wang-Rodriguez J, Xuan Y, Korrapati A, Yu V, Singh P, Grandis JR, King CC, Lippman SM, Wang XQ, Hinton A, Ongkeko WM. The non-coding landscape of head and neck squamous cell carcinoma. Oncotarget. 2016 08 09; 7(32):51211-51222. PMID: 27323410.
      View in: PubMed
    8. Yu V, Singh P, Rahimy E, Zheng H, Kuo SZ, Kim E, Wang-Rodriguez J, Ongkeko WM. RNA-seq analysis identifies key long non-coding RNAs connected to the pathogenesis of alcohol-associated head and neck squamous cell carcinoma. Oncol Lett. 2016 Oct; 12(4):2846-2853. PMID: 27698869.
      View in: PubMed
    9. Hwang JH, Lyes M, Sladewski K, Enany S, McEachern E, Mathew DP, Das S, Moshensky A, Bapat S, Pride DT, Ongkeko WM, Crotty Alexander LE. Electronic cigarette inhalation alters innate immunity and airway cytokines while increasing the virulence of colonizing bacteria. J Mol Med (Berl). 2016 06; 94(6):667-79. PMID: 26804311.
      View in: PubMed
    10. Yu V, Rahimy M, Korrapati A, Xuan Y, Zou AE, Krishnan AR, Tsui T, Aguilera JA, Advani S, Crotty Alexander LE, Brumund KT, Wang-Rodriguez J, Ongkeko WM. Electronic cigarettes induce DNA strand breaks and cell death independently of nicotine in cell lines. Oral Oncol. 2016 Jan; 52:58-65. PMID: 26547127; PMCID: PMC4891196 [Available on 01/01/17].
    11. Saad MA, Kuo SZ, Rahimy E, Zou AE, Korrapati A, Rahimy M, Kim E, Zheng H, Yu MA, Wang-Rodriguez J, Ongkeko WM. Alcohol-dysregulated miR-30a and miR-934 in head and neck squamous cell carcinoma. Mol Cancer. 2015 Oct 15; 14:181. PMID: 26472042; PMCID: PMC4608114.
    12. Zou AE, Ku J, Honda TK, Yu V, Kuo SZ, Zheng H, Xuan Y, Saad MA, Hinton A, Brumund KT, Lin JH, Wang-Rodriguez J, Ongkeko WM. Transcriptome sequencing uncovers novel long noncoding and small nucleolar RNAs dysregulated in head and neck squamous cell carcinoma. RNA. 2015 Jun; 21(6):1122-34. PMID: 25904139; PMCID: PMC4436665.
    13. Ongkeko WM, Burton D, Kiang A, Abhold E, Kuo SZ, Rahimy E, Yang M, Hoffman RM, Wang-Rodriguez J, Deftos LJ. Parathyroid hormone related-protein promotes epithelial-to-mesenchymal transition in prostate cancer. PLoS One. 2014; 9(1):e85803. PMID: 24465715; PMCID: PMC3899059.
    14. Rahimy E, Kuo SZ, Ongkeko WM. Evaluation of non-coding RNAs as potential targets in head and neck squamous cell carcinoma cancer stem cells. Curr Drug Targets. 2014; 15(13):1247-60. PMID: 25341422.
      View in: PubMed
    15. Yu MA, Kiang A, Wang-Rodriguez J, Rahimy E, Haas M, Yu V, Ellies LG, Chen J, Fan JB, Brumund KT, Weisman RA, Ongkeko WM. Nicotine promotes acquisition of stem cell and epithelial-to-mesenchymal properties in head and neck squamous cell carcinoma. PLoS One. 2012; 7(12):e51967. PMID: 23300583; PMCID: PMC3530520.
    16. Yi D, Kuo SZ, Zheng H, Abhold EL, Brown CM, Doherty JK, Wang-Rodriguez J, Harris JP, Ongkeko WM. Activation of PDGFR and EGFR promotes the acquisition of a stem cell-like phenotype in schwannomas. Otol Neurotol. 2012 Dec; 33(9):1640-7. PMID: 22935817.
      View in: PubMed
    17. Kuo SZ, Blair KJ, Rahimy E, Kiang A, Abhold E, Fan JB, Wang-Rodriguez J, Altuna X, Ongkeko WM. Salinomycin induces cell death and differentiation in head and neck squamous cell carcinoma stem cells despite activation of epithelial-mesenchymal transition and Akt. BMC Cancer. 2012 Nov 24; 12:556. PMID: 23176396; PMCID: PMC3522015.
    18. An Y, Kiang A, Lopez JP, Kuo SZ, Yu MA, Abhold EL, Chen JS, Wang-Rodriguez J, Ongkeko WM. Cigarette smoke promotes drug resistance and expansion of cancer stem cell-like side population. PLoS One. 2012; 7(11):e47919. PMID: 23144836; PMCID: PMC3489897.
    19. Abhold EL, Kiang A, Rahimy E, Kuo SZ, Wang-Rodriguez J, Lopez JP, Blair KJ, Yu MA, Haas M, Brumund KT, Altuna X, Patel A, Weisman RA, Ongkeko WM. EGFR kinase promotes acquisition of stem cell-like properties: a potential therapeutic target in head and neck squamous cell carcinoma stem cells. PLoS One. 2012; 7(2):e32459. PMID: 22384257; PMCID: PMC3288103.
    20. Abhold E, Rahimy E, Wang-Rodriguez J, Blair KJ, Yu MA, Brumund KT, Weisman RA, Ongkeko WM. Recombinant human erythropoietin promotes the acquisition of a malignant phenotype in head and neck squamous cell carcinoma cell lines in vitro. BMC Res Notes. 2011 Dec 21; 4:553. PMID: 22188703; PMCID: PMC3285115.
    21. Altuna X, Algaba J, Ongkeko W. Expression of p63 and p73 in acoustic neuroma and its possible clinical relevance. Acta Otorrinolaringol Esp. 2012 Jan-Feb; 63(1):9-14. PMID: 22000483.
      View in: PubMed
    22. Blair KJ, Kiang A, Wang-Rodriguez J, Yu MA, Doherty JK, Ongkeko WM. EGF and bFGF promote invasion that is modulated by PI3/Akt kinase and Erk in vestibular schwannoma. Otol Neurotol. 2011 Feb; 32(2):308-14. PMID: 21178801.
      View in: PubMed
    23. Altuna X, Lopez JP, Yu MA, Arandazi MJ, Harris JP, Wang-Rodriguez J, An Y, Dobrow R, Doherty JK, Ongkeko WM. Potential role of imatinib mesylate (Gleevec, STI-571) in the treatment of vestibular schwannoma. Otol Neurotol. 2011 Jan; 32(1):163-70. PMID: 21157293.
      View in: PubMed
    24. Tran Cao HS, Kaushal S, Snyder CS, Ongkeko WM, Hoffman RM, Bouvet M. Real-time imaging of tumor progression in a fluorescent orthotopic mouse model of thyroid cancer. Anticancer Res. 2010 Nov; 30(11):4415-22. PMID: 21115887; PMCID: PMC4453926.
    25. Wang XQ, Ongkeko WM, Chen L, Yang ZF, Lu P, Chen KK, Lopez JP, Poon RT, Fan ST. Octamer 4 (Oct4) mediates chemotherapeutic drug resistance in liver cancer cells through a potential Oct4-AKT-ATP-binding cassette G2 pathway. Hepatology. 2010 Aug; 52(2):528-39. PMID: 20683952.
      View in: PubMed
    26. An Y, Ongkeko WM. ABCG2: the key to chemoresistance in cancer stem cells? Expert Opin Drug Metab Toxicol. 2009 Dec; 5(12):1529-42. PMID: 19708828.
      View in: PubMed
    27. Ahmad ZK, Altuna X, Lopez JP, An Y, Wang-Rodriguez J, Juneja VR, Chen JS, Arandazi MJ, Aguilera J, Harris JP, Ongkeko WM. p73 expression and function in vestibular schwannoma. Arch Otolaryngol Head Neck Surg. 2009 Jul; 135(7):662-9. PMID: 19620587.
      View in: PubMed
    28. Chu TS, Chen JS, Lopez JP, Pardo FS, Aguilera J, Ongkeko WM. Imatinib-mediated inactivation of Akt regulates ABCG2 function in head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg. 2008 Sep; 134(9):979-84. PMID: 18794444.
      View in: PubMed
    29. Lopez JP, Wang-Rodriguez J, Chang CY, Sneh G, Yu MA, Pardo FS, Aguilera J, Ongkeko WM. Gefitinib (Iressa) potentiates the effect of ionizing radiation in thyroid cancer cell lines. Laryngoscope. 2008 Aug; 118(8):1372-6. PMID: 18475209.
      View in: PubMed
    30. Doherty JK, Ongkeko W, Crawley B, Andalibi A, Ryan AF. ErbB and Nrg: potential molecular targets for vestibular schwannoma pharmacotherapy. Otol Neurotol. 2008 Jan; 29(1):50-7. PMID: 18199957.
      View in: PubMed
    31. Lopez JP, Wang-Rodriguez J, Chang C, Chen JS, Pardo FS, Aguilera J, Ongkeko WM. Gefitinib inhibition of drug resistance to doxorubicin by inactivating ABCG2 in thyroid cancer cell lines. Arch Otolaryngol Head Neck Surg. 2007 Oct; 133(10):1022-7. PMID: 17938326.
      View in: PubMed
    32. Pham TT, Ongkeko WM, An Y, Yi ES. Protein expression of the tumor suppressors p16INK4A and p53 and disease progression in recurrent respiratory papillomatosis. Laryngoscope. 2007 Feb; 117(2):253-7. PMID: 17277618.
      View in: PubMed
    33. Wang-Rodriguez J, Lopez JP, Altuna X, Chu TS, Weisman RA, Ongkeko WM. STI-571 (Gleevec) potentiates the effect of cisplatin in inhibiting the proliferation of head and neck squamous cell carcinoma in vitro. Laryngoscope. 2006 Aug; 116(8):1409-16. PMID: 16885745.
      View in: PubMed
    34. Ongkeko WM, An Y, Chu TS, Aguilera J, Dang CL, Wang-Rodriguez J. Gleevec suppresses p63 expression in head and neck squamous cell carcinoma despite p63 activation by DNA-damaging agents. Laryngoscope. 2006 Aug; 116(8):1390-6. PMID: 16885742.
      View in: PubMed
    35. Chen JS, Pardo FS, Wang-Rodriguez J, Chu TS, Lopez JP, Aguilera J, Altuna X, Weisman RA, Ongkeko WM. EGFR regulates the side population in head and neck squamous cell carcinoma. Laryngoscope. 2006 Mar; 116(3):401-6. PMID: 16540898.
      View in: PubMed
    36. Ongkeko WM, Altuna X, Weisman RA, Wang-Rodriguez J. Expression of protein tyrosine kinases in head and neck squamous cell carcinomas. Am J Clin Pathol. 2005 Jul; 124(1):71-6. PMID: 15923166.
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