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Weg Ongkeko

Title(s)Associate Adjunct Professor, Surgery
SchoolHealth Sciences
Address9500 Gilman Drive #9151
La Jolla CA 92093
Phone858-552-8585
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The Liver Microbiome Is Implicated in Cancer Prognosis and Modulated by Alcohol and Hepatitis B. Cancers (Basel). 2020 Jun 21; 12(6). Chakladar J, Wong LM, Kuo SZ, Li WT, Yu MA, Chang EY, Wang XQ, Ongkeko WM. PMID: 32575865.
      View in: PubMed   Mentions:
    2. Comparative Analysis of Age- and Gender-Associated Microbiome in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma. Cancers (Basel). 2020 Jun 02; 12(6). Wong LM, Shende N, Li WT, Castaneda G, Apostol L, Chang EY, Ongkeko WM. PMID: 32498338.
      View in: PubMed   Mentions:
    3. Smoking-Mediated Upregulation of the Androgen Pathway Leads to Increased SARS-CoV-2 Susceptibility. Int J Mol Sci. 2020 May 21; 21(10). Chakladar J, Shende N, Li WT, Rajasekaran M, Chang EY, Ongkeko WM. PMID: 32455539.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    4. Redirecting extracellular proteases to molecularly guide radiosensitizing drugs to tumors. Biomaterials. 2020 Jul; 248:120032. Hingorani DV, Crisp JL, Doan MK, Camargo MF, Quraishi MA, Aguilera J, Gilardi M, Gross LA, Jiang T, Li WT, Ongkeko WM, Cohen EEW, Gutkind JS, Adams SR, Advani SJ. PMID: 32304937.
      View in: PubMed   Mentions:    Fields:    
    5. Characterization of urethral fibrosis in a rabbit model: Potential roles of Wnt-ß catenin pathway and epithelial to mesenchymal transition. Neurourol Urodyn. 2020 02; 39(2):625-632. Tai JW, Yu H, Chilukuri AT, Bhargava R, Deshpande R, Li W, Ongkeko WM, Bhargava V, Rajasekaran MR. PMID: 31961960.
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    6. The Landscape of Long Non-Coding RNA Dysregulation and Clinical Relevance in Muscle Invasive Bladder Urothelial Carcinoma. Cancers (Basel). 2019 Dec 02; 11(12). Shen H, Wong LM, Li WT, Chu M, High RA, Chang EY, Wang-Rodriguez J, Ongkeko WM. PMID: 31810243.
      View in: PubMed   Mentions:
    7. Etiology-Specific Analysis of Hepatocellular Carcinoma Transcriptome Reveals Genetic Dysregulation in Pathways Implicated in Immunotherapy Efficacy. Cancers (Basel). 2019 Aug 30; 11(9). Li WT, Zou AE, Honda CO, Zheng H, Wang XQ, Kisseleva T, Chang EY, Ongkeko WM. PMID: 31480259.
      View in: PubMed   Mentions:
    8. Papillary Thyroid Carcinoma Variants are Characterized by Co-dysregulation of Immune and Cancer Associated Genes. Cancers (Basel). 2019 Aug 15; 11(8). Chakladar J, Li WT, Bouvet M, Chang EY, Wang-Rodriguez J, Ongkeko WM. PMID: 31443155.
      View in: PubMed   Mentions:
    9. Randomised controlled trial of real-time feedback and brief coaching to reduce indoor smoking. Tob Control. 2020 Mar; 29(2):183-190. Hovell MF, Bellettiere J, Liles S, Nguyen B, Berardi V, Johnson C, Matt GE, Malone J, Boman-Davis MC, Quintana PJE, Obayashi S, Chatfield D, Robinson R, Blumberg EJ, Ongkeko WM, Klepeis NE, Hughes SC. PMID: 30770436.
      View in: PubMed   Mentions:    Fields:    
    10. Identification and characterization of dysregulated P-element induced wimpy testis-interacting RNAs in head and neck squamous cell carcinoma. Oncol Lett. 2019 Mar; 17(3):2615-2622. Saad MA, Ku J, Kuo SZ, Li PX, Zheng H, Yu MA, Wang-Rodriguez J, Ongkeko WM. PMID: 30854037.
      View in: PubMed   Mentions:
    11. Metformin Results in Diametrically Opposed Effects by Targeting Non-Stem Cancer Cells but Protecting Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma. Int J Mol Sci. 2019 Jan 07; 20(1). Kuo SZ, Honda CO, Li WT, Honda TK, Kim E, Altuna X, Abhold E, Wang-Rodriguez J, Ongkeko WM. PMID: 30621095.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    12. Functional Genomics Profiling of Bladder Urothelial Carcinoma MicroRNAome as a Potential Biomarker. Neoplasia. 2018 04; 20(4):364-373. Li WT, Zheng H, Nguyen V, Wang-Rodriguez J, Ongkeko WM. PMID: 29544183.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Computational methods reveal novel functionalities of PIWI-interacting RNAs in human papillomavirus-induced head and neck squamous cell carcinoma. Oncotarget. 2018 Jan 12; 9(4):4614-4624. Krishnan AR, Qu Y, Li PX, Zou AE, Califano JA, Wang-Rodriguez J, Ongkeko WM. PMID: 29435129.
      View in: PubMed   Mentions: 1     Fields:    
    14. Alcohol and hepatitis virus-dysregulated lncRNAs as potential biomarkers for hepatocellular carcinoma. Oncotarget. 2018 Jan 02; 9(1):224-235. Zheng H, Li P, Kwok JG, Korrapati A, Li WT, Qu Y, Wang XQ, Kisseleva T, Wang-Rodriguez J, Ongkeko WM. PMID: 29416609.
      View in: PubMed   Mentions: 1     Fields:    
    15. A comprehensive study of smoking-specific microRNA alterations in head and neck squamous cell carcinoma. Oral Oncol. 2017 09; 72:56-64. Krishnan AR, Zheng H, Kwok JG, Qu Y, Zou AE, Korrapati A, Li PX, Califano JA, Hovell MF, Wang-Rodriguez J, Ongkeko WM. PMID: 28797462.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    16. Alcohol-dysregulated microRNAs in hepatitis B virus-related hepatocellular carcinoma. PLoS One. 2017; 12(5):e0178547. Zheng H, Zou AE, Saad MA, Wang XQ, Kwok JG, Korrapati A, Li P, Kisseleva T, Wang-Rodriguez J, Ongkeko WM. PMID: 28562643.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    17. Smoking status regulates a novel panel of PIWI-interacting RNAs in head and neck squamous cell carcinoma. Oral Oncol. 2017 02; 65:68-75. Krishnan AR, Korrapati A, Zou AE, Qu Y, Wang XQ, Califano JA, Wang-Rodriguez J, Lippman SM, Hovell MF, Ongkeko WM. PMID: 28109471.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. The non-coding landscape of head and neck squamous cell carcinoma. Oncotarget. 2016 08 09; 7(32):51211-51222. Zou AE, Zheng H, Saad MA, Rahimy M, Ku J, Kuo SZ, Honda TK, Wang-Rodriguez J, Xuan Y, Korrapati A, Yu V, Singh P, Grandis JR, King CC, Lippman SM, Wang XQ, Hinton A, Ongkeko WM. PMID: 27323410.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    19. RNA-seq analysis identifies key long non-coding RNAs connected to the pathogenesis of alcohol-associated head and neck squamous cell carcinoma. Oncol Lett. 2016 Oct; 12(4):2846-2853. Yu V, Singh P, Rahimy E, Zheng H, Kuo SZ, Kim E, Wang-Rodriguez J, Ongkeko WM. PMID: 27698869.
      View in: PubMed   Mentions:
    20. Electronic cigarette inhalation alters innate immunity and airway cytokines while increasing the virulence of colonizing bacteria. J Mol Med (Berl). 2016 06; 94(6):667-79. Hwang JH, Lyes M, Sladewski K, Enany S, McEachern E, Mathew DP, Das S, Moshensky A, Bapat S, Pride DT, Ongkeko WM, Crotty Alexander LE. PMID: 26804311.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    21. Electronic cigarettes induce DNA strand breaks and cell death independently of nicotine in cell lines. Oral Oncol. 2016 Jan; 52:58-65. Yu V, Rahimy M, Korrapati A, Xuan Y, Zou AE, Krishnan AR, Tsui T, Aguilera JA, Advani S, Crotty Alexander LE, Brumund KT, Wang-Rodriguez J, Ongkeko WM. PMID: 26547127.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    22. Alcohol-dysregulated miR-30a and miR-934 in head and neck squamous cell carcinoma. Mol Cancer. 2015 Oct 15; 14:181. Saad MA, Kuo SZ, Rahimy E, Zou AE, Korrapati A, Rahimy M, Kim E, Zheng H, Yu MA, Wang-Rodriguez J, Ongkeko WM. PMID: 26472042.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    23. Transcriptome sequencing uncovers novel long noncoding and small nucleolar RNAs dysregulated in head and neck squamous cell carcinoma. RNA. 2015 Jun; 21(6):1122-34. Zou AE, Ku J, Honda TK, Yu V, Kuo SZ, Zheng H, Xuan Y, Saad MA, Hinton A, Brumund KT, Lin JH, Wang-Rodriguez J, Ongkeko WM. PMID: 25904139.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    24. Parathyroid hormone related-protein promotes epithelial-to-mesenchymal transition in prostate cancer. PLoS One. 2014; 9(1):e85803. Ongkeko WM, Burton D, Kiang A, Abhold E, Kuo SZ, Rahimy E, Yang M, Hoffman RM, Wang-Rodriguez J, Deftos LJ. PMID: 24465715.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    25. Evaluation of non-coding RNAs as potential targets in head and neck squamous cell carcinoma cancer stem cells. Curr Drug Targets. 2014; 15(13):1247-60. Rahimy E, Kuo SZ, Ongkeko WM. PMID: 25341422.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    26. Nicotine promotes acquisition of stem cell and epithelial-to-mesenchymal properties in head and neck squamous cell carcinoma. PLoS One. 2012; 7(12):e51967. Yu MA, Kiang A, Wang-Rodriguez J, Rahimy E, Haas M, Yu V, Ellies LG, Chen J, Fan JB, Brumund KT, Weisman RA, Ongkeko WM. PMID: 23300583.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    27. Activation of PDGFR and EGFR promotes the acquisition of a stem cell-like phenotype in schwannomas. Otol Neurotol. 2012 Dec; 33(9):1640-7. Yi D, Kuo SZ, Zheng H, Abhold EL, Brown CM, Doherty JK, Wang-Rodriguez J, Harris JP, Ongkeko WM. PMID: 22935817.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    28. Salinomycin induces cell death and differentiation in head and neck squamous cell carcinoma stem cells despite activation of epithelial-mesenchymal transition and Akt. BMC Cancer. 2012 Nov 24; 12:556. Kuo SZ, Blair KJ, Rahimy E, Kiang A, Abhold E, Fan JB, Wang-Rodriguez J, Altuna X, Ongkeko WM. PMID: 23176396.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    29. Cigarette smoke promotes drug resistance and expansion of cancer stem cell-like side population. PLoS One. 2012; 7(11):e47919. An Y, Kiang A, Lopez JP, Kuo SZ, Yu MA, Abhold EL, Chen JS, Wang-Rodriguez J, Ongkeko WM. PMID: 23144836.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    30. EGFR kinase promotes acquisition of stem cell-like properties: a potential therapeutic target in head and neck squamous cell carcinoma stem cells. PLoS One. 2012; 7(2):e32459. Abhold EL, Kiang A, Rahimy E, Kuo SZ, Wang-Rodriguez J, Lopez JP, Blair KJ, Yu MA, Haas M, Brumund KT, Altuna X, Patel A, Weisman RA, Ongkeko WM. PMID: 22384257.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    31. Progress and pitfalls in the identification of cancer stem cell-targeting therapies in head and neck squamous cell carcinoma. Curr Med Chem. 2012; 19(35):6056-64. Kiang A, Yu MA, Ongkeko WM. PMID: 22963569.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    32. Recombinant human erythropoietin promotes the acquisition of a malignant phenotype in head and neck squamous cell carcinoma cell lines in vitro. BMC Res Notes. 2011 Dec 21; 4:553. Abhold E, Rahimy E, Wang-Rodriguez J, Blair KJ, Yu MA, Brumund KT, Weisman RA, Ongkeko WM. PMID: 22188703.
      View in: PubMed   Mentions: 7     Fields:    
    33. Expression of p63 and p73 in acoustic neuroma and its possible clinical relevance. Acta Otorrinolaringol Esp. 2012 Jan-Feb; 63(1):9-14. Altuna X, Algaba J, Ongkeko W. PMID: 22000483.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. EGF and bFGF promote invasion that is modulated by PI3/Akt kinase and Erk in vestibular schwannoma. Otol Neurotol. 2011 Feb; 32(2):308-14. Blair KJ, Kiang A, Wang-Rodriguez J, Yu MA, Doherty JK, Ongkeko WM. PMID: 21178801.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    35. Potential role of imatinib mesylate (Gleevec, STI-571) in the treatment of vestibular schwannoma. Otol Neurotol. 2011 Jan; 32(1):163-70. Altuna X, Lopez JP, Yu MA, Arandazi MJ, Harris JP, Wang-Rodriguez J, An Y, Dobrow R, Doherty JK, Ongkeko WM. PMID: 21157293.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    36. Real-time imaging of tumor progression in a fluorescent orthotopic mouse model of thyroid cancer. Anticancer Res. 2010 Nov; 30(11):4415-22. Tran Cao HS, Kaushal S, Snyder CS, Ongkeko WM, Hoffman RM, Bouvet M. PMID: 21115887.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    37. Octamer 4 (Oct4) mediates chemotherapeutic drug resistance in liver cancer cells through a potential Oct4-AKT-ATP-binding cassette G2 pathway. Hepatology. 2010 Aug; 52(2):528-39. Wang XQ, Ongkeko WM, Chen L, Yang ZF, Lu P, Chen KK, Lopez JP, Poon RT, Fan ST. PMID: 20683952.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    38. ABCG2: the key to chemoresistance in cancer stem cells? Expert Opin Drug Metab Toxicol. 2009 Dec; 5(12):1529-42. An Y, Ongkeko WM. PMID: 19708828.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    39. p73 expression and function in vestibular schwannoma. Arch Otolaryngol Head Neck Surg. 2009 Jul; 135(7):662-9. Ahmad ZK, Altuna X, Lopez JP, An Y, Wang-Rodriguez J, Juneja VR, Chen JS, Arandazi MJ, Aguilera J, Harris JP, Ongkeko WM. PMID: 19620587.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    40. Imatinib-mediated inactivation of Akt regulates ABCG2 function in head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg. 2008 Sep; 134(9):979-84. Chu TS, Chen JS, Lopez JP, Pardo FS, Aguilera J, Ongkeko WM. PMID: 18794444.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    41. Gefitinib (Iressa) potentiates the effect of ionizing radiation in thyroid cancer cell lines. Laryngoscope. 2008 Aug; 118(8):1372-6. Lopez JP, Wang-Rodriguez J, Chang CY, Sneh G, Yu MA, Pardo FS, Aguilera J, Ongkeko WM. PMID: 18475209.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    42. ErbB and Nrg: potential molecular targets for vestibular schwannoma pharmacotherapy. Otol Neurotol. 2008 Jan; 29(1):50-7. Doherty JK, Ongkeko W, Crawley B, Andalibi A, Ryan AF. PMID: 18199957.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    43. Gefitinib inhibition of drug resistance to doxorubicin by inactivating ABCG2 in thyroid cancer cell lines. Arch Otolaryngol Head Neck Surg. 2007 Oct; 133(10):1022-7. Lopez JP, Wang-Rodriguez J, Chang C, Chen JS, Pardo FS, Aguilera J, Ongkeko WM. PMID: 17938326.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    44. Protein expression of the tumor suppressors p16INK4A and p53 and disease progression in recurrent respiratory papillomatosis. Laryngoscope. 2007 Feb; 117(2):253-7. Pham TT, Ongkeko WM, An Y, Yi ES. PMID: 17277618.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    45. STI-571 (Gleevec) potentiates the effect of cisplatin in inhibiting the proliferation of head and neck squamous cell carcinoma in vitro. Laryngoscope. 2006 Aug; 116(8):1409-16. Wang-Rodriguez J, Lopez JP, Altuna X, Chu TS, Weisman RA, Ongkeko WM. PMID: 16885745.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    46. Gleevec suppresses p63 expression in head and neck squamous cell carcinoma despite p63 activation by DNA-damaging agents. Laryngoscope. 2006 Aug; 116(8):1390-6. Ongkeko WM, An Y, Chu TS, Aguilera J, Dang CL, Wang-Rodriguez J. PMID: 16885742.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    47. EGFR regulates the side population in head and neck squamous cell carcinoma. Laryngoscope. 2006 Mar; 116(3):401-6. Chen JS, Pardo FS, Wang-Rodriguez J, Chu TS, Lopez JP, Aguilera J, Altuna X, Weisman RA, Ongkeko WM. PMID: 16540898.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    48. Expression of protein tyrosine kinases in head and neck squamous cell carcinomas. Am J Clin Pathol. 2005 Jul; 124(1):71-6. Ongkeko WM, Altuna X, Weisman RA, Wang-Rodriguez J. PMID: 15923166.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    49. [Immunohistochemistry study of EGFR expression in head and neck squamous cell carcinoma]. Acta Otorrinolaringol Esp. 2005 Apr; 56(4):143-6. Altuna Mariezkurrena X, Algaba Guimerá J, Wang Rodríguez J, Weisman R, Ongkeko W. PMID: 15871288.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    50. A possible role of p73 on the modulation of p53 level through MDM2. Cancer Res. 2001 Feb 15; 61(4):1598-603. Wang XQ, Ongkeko WM, Lau AW, Leung KM, Poon RY. PMID: 11245471.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    51. MDM2 and MDMX bind and stabilize the p53-related protein p73. Curr Biol. 1999 Jul 29-Aug 12; 9(15):829-32. Ongkeko WM, Wang XQ, Siu WY, Lau AW, Yamashita K, Harris AL, Cox LS, Poon RY. PMID: 10469568.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    52. p53 regulates Cdc2 independently of inhibitory phosphorylation to reinforce radiation-induced G2 arrest in human cells. Oncogene. 1998 Aug 13; 17(6):673-84. Winters ZE, Ongkeko WM, Harris AL, Norbury CJ. PMID: 9715268.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    53. p53 regulates the minimal promoter of the human topoisomerase IIalpha gene. Nucleic Acids Res. 1996 Nov 15; 24(22):4464-70. Sandri MI, Isaacs RJ, Ongkeko WM, Harris AL, Hickson ID, Broggini M, Vikhanskaya F. PMID: 8948636.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    54. Inactivation of Cdc2 increases the level of apoptosis induced by DNA damage. J Cell Sci. 1995 Aug; 108 ( Pt 8):2897-904. Ongkeko W, Ferguson DJ, Harris AL, Norbury C. PMID: 7593329.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
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