Tatyana Bodrug

Title(s)	Postdoctoral Scholar, Cellular and Molecular Medicine
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C). Nat Struct Mol Biol. 2023 Nov; 30(11):1663-1674. Bodrug T, Welsh KA, Bolhuis DL, Paul?konis E, Martinez-Chacin RC, Liu B, Pinkin N, Bonacci T, Cui L, Xu P, Roscow O, Amann SJ, Grishkovskaya I, Emanuele MJ, Harrison JS, Steimel JP, Hahn KM, Zhang W, Zhong ED, Haselbach D, Brown NG. PMID: 37735619; PMCID: PMC10643132.

View in: PubMed Mentions: Fields:
Mol Molecular Biology
Translation:Humans Cells
The kinesin-5 tail and bipolar minifilament domains are the origin of its microtubule crosslinking and sliding activity. Mol Biol Cell. 2023 10 01; 34(11):ar111. Nithianantham S, Iwanski MK, Gaska I, Pandey H, Bodrug T, Inagaki S, Major J, Brouhard GJ, Gheber L, Rosenfeld SS, Forth S, Hendricks AG, Al-Bassam J. PMID: 37610838; PMCID: PMC10559304.

View in: PubMed Mentions: Fields:
Cel Cell Biology Mol Molecular Biology
Frozen in time: analyzing molecular dynamics with time-resolved cryo-EM. Structure. 2023 01 05; 31(1):4-19. Amann SJ, Keihsler D, Bodrug T, Brown NG, Haselbach D. PMID: 36584678; PMCID: PMC9825670.

View in: PubMed Mentions: 5 Fields:
Bio Biochemistry Bio Biotechnology Mol Molecular Biology
Translation:Cells
Examining the mechanistic relationship of APC/CCDH1 and its interphase inhibitor EMI1. Protein Sci. 2022 06; 31(6):e4324. Bolhuis DL, Martinez-Chacin RC, Welsh KA, Bodrug T, Cui L, Emanuele MJ, Brown NG. PMID: 35634770; PMCID: PMC9112349.

View in: PubMed Mentions: 2 Fields:
Bio Biochemistry
APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain. Mol Cell. 2022 01 06; 82(1):90-105.e13. Ferguson CJ, Urso O, Bodrug T, Gassaway BM, Watson ER, Prabu JR, Lara-Gonzalez P, Martinez-Chacin RC, Wu DY, Brigatti KW, Puffenberger EG, Taylor CM, Haas-Givler B, Jinks RN, Strauss KA, Desai A, Gabel HW, Gygi SP, Schulman BA, Brown NG, Bonni A. PMID: 34942119; PMCID: PMC8741739.

View in: PubMed Mentions: 3 Fields:
Cel Cell Biology Mol Molecular Biology
Intricate Regulatory Mechanisms of the Anaphase-Promoting Complex/Cyclosome and Its Role in Chromatin Regulation. Front Cell Dev Biol. 2021; 9:687515. Bodrug T, Welsh KA, Hinkle M, Emanuele MJ, Brown NG. PMID: 34109183; PMCID: PMC8182066.

View in: PubMed Mentions: 9
Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming. Nat Struct Mol Biol. 2020 06; 27(6):550-560. Martinez-Chacin RC, Bodrug T, Bolhuis DL, Kedziora KM, Bonacci T, Ordureau A, Gibbs ME, Weissmann F, Qiao R, Grant GD, Cook JG, Peters JM, Wade Harper J, Emanuele MJ, Brown NG. PMID: 32393902; PMCID: PMC7293561.

View in: PubMed Mentions: 21 Fields:
Mol Molecular Biology
Translation:Humans Cells
Quantifying the heterogeneity of macromolecular machines by mass photometry. Nat Commun. 2020 04 14; 11(1):1772. Sonn-Segev A, Belacic K, Bodrug T, Young G, VanderLinden RT, Schulman BA, Schimpf J, Friedrich T, Dip PV, Schwartz TU, Bauer B, Peters JM, Struwe WB, Benesch JLP, Brown NG, Haselbach D, Kukura P. PMID: 32286308; PMCID: PMC7156492.

View in: PubMed Mentions: 77 Fields:
Bio Biology Sci Science
Translation:Animals Cells
Paradoxical mitotic exit induced by a small molecule inhibitor of APC/CCdc20. Nat Chem Biol. 2020 05; 16(5):546-555. Richeson KV, Bodrug T, Sackton KL, Yamaguchi M, Paulo JA, Gygi SP, Schulman BA, Brown NG, King RW. PMID: 32152539; PMCID: PMC7289404.

View in: PubMed Mentions: 11 Fields:
Bio Biology Che Chemistry
Translation:Humans Cells
The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding. Elife. 2020 01 20; 9. Bodrug T, Wilson-Kubalek EM, Nithianantham S, Thompson AF, Alfieri A, Gaska I, Major J, Debs G, Inagaki S, Gutierrez P, Gheber L, McKenney RJ, Sindelar CV, Milligan R, Stumpff J, Rosenfeld SS, Forth ST, Al-Bassam J. PMID: 31958056; PMCID: PMC7015671.

View in: PubMed Mentions: 15 Fields:
Bio Biology
Translation:Humans Cells
UBE2S Learns Self-Control. Structure. 2019 08 06; 27(8):1185-1187. Bodrug T, Brown NG. PMID: 31390542; PMCID: PMC7337262.

View in: PubMed Mentions: Fields:
Bio Biochemistry Bio Biotechnology Mol Molecular Biology
Translation:Cells