Julio Pimentel

Title(s)	Postdoctoral Scholar, Pharmacology
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
ORCID	0000-0003-3475-5244
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Biography

Education and Training

Wayne State University School of Medicine , Detroit, MI	PhD	06/2023	Oncology
Harvard Medical School, Boston, MA	Postgrad	08/2018	Translational Medicine
University of Miami Miller School of Medicine, Miami, FL	MSCTI	07/2018	Clinical Research
California State University Stanislaus , Turlock, CA	BS	12/2014	Biological Sciences (Molecular Biology)

Awards and Honors

University of California, San Diego	2023 -	2025	IRACDA Fellow
University of California San Diego	2023 -	2025	NHLBI Diversity Supplement Award
United States White House	2023		Congratulatory letter from US President Joe Biden
University of Miami Miller School of Medicine	2023		Med’Canes Spring 2024 newsletter as an alumni feature.
University of California, Irvine	2024		University of California, Irvine Training Fellowship in Cancer Systems Biology
World Top Scientists	2024		Young Scientist Award
American Journal of Physiology	2024		Co-Authored Review Paper Cover Spotlight

Overview

Dr. Julio M. Pimentel is a K12 NHLBI-funded postdoctoral scholar in the Department of Pharmacology at the University of California, San Diego School of Medicine (UCSDSM). He is also a candidate for assistant professor through the Institutional Research Academic Career Development Award (IRACDA) Program. Dr. Pimentel is a nationally recognized cancer researcher who has garnered numerous accolades for his work with his former PhD adviser, Dr. Gen Sheng Wu, on a novel non-canonical role for PD-L1 in TRAIL resistance in triple-negative breast cancer. Among his other awards are official recognition from US President Donald Trump and Joe Biden, the Governor of Michigan Gretchen Whitmer, as well as being awarded a 40 Under 40 and National Latino Leader twice. Dr. Pimentel researches the underlying mechanisms that impart therapeutic resistance in cancers, particularly those associated with vascular inflammation, as well as evasion of apoptosis and immunosurveillance. His current mentor is Dr. JoAnn Trejo, a member of the National Academy of Medicine, Senior Assistant Vice Chancellor for Health Sciences Faculty Affairs, and UCSD Professor.

Interests

Breast cancer, Triple-negative breast cancer, Therapy resistance, PD-L1, Apoptosis, TRAIL, Immune Evasion, G-protein coupled receptors, Inflammation, IL-6, STEM diversity, Cancer diversity, cytokines, IL-1alpha, Immunosurveillance, PAR1 signaling, p38

Websites

In The News

	Cancer researcher focuses on the underrepresented (05/01/2024)
	Early experiences in medicine inspire Julio Pimentel to tackle disparities in cancer research (07/19/23)
	Dr. Julio M. Pimentel is One of The Very Few Hispanic Men of Color in His Field of Cancer Research (09/14/2024)

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Ubiquitin-driven G Protein-Coupled Receptor Inflammatory Signaling at the Endosome. 2024. Cheng N, Pimentel J.M, Trejo J. View Publication.
American Journal of Cancer Research. The role of the immune response and inflammatory pathways in TNF-related apoptosis-inducing ligand (TRAIL) resistance in triple-negative breast cancer cells. 2023; 10(13). JM Pimentel, JY Zhou, GS Wu. View Publication.
The mechanisms of TRAIL resistance in triple-negative breast cancer. 2023. Pimentel JM. . View Publication.
Molecular Carcinogenesis. Cover Image. 2023; 62(2). Pimentel JM, Zhou, J.-Y. and Wu, G.S. View Publication.
The Role of TRAIL in Apoptosis and Immunosurveillance in Cancer. Cancers (Basel). 2023 May 13; 15(10). Pimentel JM, Zhou JY, Wu GS. PMID: 37345089; PMCID: PMC10216286.

View in: PubMed Mentions: 16
Regulation of programmed death ligand 1 (PD-L1) expression by TNF-related apoptosis-inducing ligand (TRAIL) in triple-negative breast cancer cells. Mol Carcinog. 2023 02; 62(2):135-144. Pimentel JM, Zhou JY, Wu GS. PMID: 36239572; PMCID: PMC10015553.

View in: PubMed Mentions: 5 Fields:
Mol Molecular Biology Neo Neoplasms
Translation:Humans Cells
Frontiers in Oncology. Proteomic Analysis Identifies p62/SQSTM1 as a Critical Player in PARP Inhibitor Resistance. 2022; 12. Uddin MH, Zhou JY, Pimentel J, Patrick SM, Kim S, Shekhar MP, Wu GS. View Publication.
Targeting PP2A inhibits the growth of triple-negative breast cancer cells. Cell Cycle. 2020 03; 19(5):592-600. Uddin MH, Pimentel JM, Chatterjee M, Allen JE, Zhuang Z, Wu GS. PMID: 32011210; PMCID: PMC7100985.

View in: PubMed Mentions: 6 Fields:
Cel Cell Biology
Translation:Humans Animals Cells
Cancer research (Chicago, Ill.),. Abstract 5264: Metabolic reprogramming with β-alanine to overcome chemotherapy resistance in pancreatic cancer. 2019; 79:5624-5624. Danny Yakoub, Smitha T. Totiger, Alexandra Moran, Sujit Suwal, Julio Pimentel, Lauren O'Donell, Jamie Walls, Nagaraj Nagathihalli and Nipun Merchant. View Publication.
Semantic Scholar. Characterizing and Detecting How Protein Fragments Pass Through the Intestinal Epithelial Layer With Emphasis on the Absorption of Collagen ' s Fragments. 2014. Pimentel JM, & Stone K. View Publication.