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Transitional dendritic cells are distinct from conventional DC2 precursors and mediate proinflammatory antiviral responses. Nat Immunol. 2023 08; 24(8):1265-1280.
Sulczewski FB, Maqueda-Alfaro RA, Alcántara-Hernández M, Perez OA, Saravanan S, Yun TJ, Seong D, Arroyo Hornero R, Raquer-McKay HM, Esteva E, Lanzar ZR, Leylek RA, Adams NM, Das A, Rahman AH, Gottfried-Blackmore A, Reizis B, Idoyaga J. PMID: 37414907.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression. Nat Methods. 2023 07; 20(7):1070-1081.
Zengel J, Wang YX, Seo JW, Ning K, Hamilton JN, Wu B, Raie M, Holbrook C, Su S, Clements DR, Pillay S, Puschnik AS, Winslow MM, Idoyaga J, Nagamine CM, Sun Y, Mahajan VB, Ferrara KW, Blau HM, Carette JE. PMID: 37291262; PMCID: PMC10333121.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
-
Rapid recruitment and IFN-I-mediated activation of monocytes dictate focal radiotherapy efficacy. Sci Immunol. 2023 Jun 02; 8(84):eadd7446.
Tadepalli S, Clements DR, Saravanan S, Arroyo Hornero R, Lüdtke A, Blackmore B, Paulo JA, Gottfried-Blackmore A, Seong D, Park S, Chan L, Kopecky BJ, Liu Z, Ginhoux F, Lavine KJ, Murphy JP, Mack M, Graves EE, Idoyaga J. PMID: 37294749; PMCID: PMC10340791.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Plasmacytoid dendritic cells: A dendritic cell in disguise. Mol Immunol. 2023 07; 159:38-45.
Arroyo Hornero R, Idoyaga J. PMID: 37269733.
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PubMed Mentions:
1 Fields:
Translation:
Cells
-
Reclassification of plasmacytoid dendritic cells as innate lymphocytes is premature. Nat Rev Immunol. 2023 05; 23(5):336-337.
Reizis B, Idoyaga J, Dalod M, Barrat F, Naik S, Trinchieri G, Tussiwand R, Cella M, Colonna M. PMID: 36959479.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
In vivo bioluminescence imaging of granzyme B activity in tumor response to cancer immunotherapy. Cell Chem Biol. 2022 Oct 20; 29(10):1556-1567.e6.
Chen M, Zhou K, Dai SY, Tadepalli S, Balakrishnan PB, Xie J, Rami FEI, Dai T, Cui L, Idoyaga J, Rao J. PMID: 36103874; PMCID: PMC9588750.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Injectable Nanoparticle-Based Hydrogels Enable the Safe and Effective Deployment of Immunostimulatory CD40 Agonist Antibodies. Adv Sci (Weinh). 2022 10; 9(28):e2103677.
Correa S, Meany EL, Gale EC, Klich JH, Saouaf OM, Mayer AT, Xiao Z, Liong CS, Brown RA, Maikawa CL, Grosskopf AK, Mann JL, Idoyaga J, Appel EA. PMID: 35975424; PMCID: PMC9534946.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans. Science. 2022 05 13; 376(6594):eabl4896.
Tabula Sapiens Consortium*, Jones RC, Karkanias J, Krasnow MA, Pisco AO, Quake SR, Salzman J, Yosef N, Bulthaup B, Brown P, Harper W, Hemenez M, Ponnusamy R, Salehi A, Sanagavarapu BA, Spallino E, Aaron KA, Concepcion W, Gardner JM, Kelly B, Neidlinger N, Wang Z, Crasta S, Kolluru S, Morri M, Pisco AO, Tan SY, Travaglini KJ, Xu C, Alcántara-Hernández M, Almanzar N, Antony J, Beyersdorf B, Burhan D, Calcuttawala K, Carter MM, Chan CKF, Chang CA, Chang S, Colville A, Crasta S, Culver RN, Cvijovic I, D'Amato G, Ezran C, Galdos FX, Gillich A, Goodyer WR, Hang Y, Hayashi A, Houshdaran S, Huang X, Irwin JC, Jang S, Juanico JV, Kershner AM, Kim S, Kiss B, Kolluru S, Kong W, Kumar ME, Kuo AH, Leylek R, Li B, Loeb GB, Lu WJ, Mantri S, Markovic M, McAlpine PL, de Morree A, Morri M, Mrouj K, Mukherjee S, Muser T, Neuhöfer P, Nguyen TD, Perez K, Phansalkar R, Pisco AO, Puluca N, Qi Z, Rao P, Raquer-McKay H, Schaum N, Scott B, Seddighzadeh B, Segal J, Sen S, Sikandar S, Spencer SP, Steffes LC, Subramaniam VR, Swarup A, Swift M, Travaglini KJ, Van Treuren W, Trimm E, Veizades S, Vijayakumar S, Vo KC, Vorperian SK, Wang W, Weinstein HNW, Winkler J, Wu TTH, Xie J, Yung AR, Zhang Y, Detweiler AM, Mekonen H, Neff NF, Sit RV, Tan M, Yan J, Bean GR, Charu V, Forgó E, Martin BA, Ozawa MG, Silva O, Tan SY, Toland A, Vemuri VNP, Afik S, Awayan K, Botvinnik OB, Byrne A, Chen M, Dehghannasiri R, Detweiler AM, Gayoso A, Granados AA, Li Q, Mahmoudabadi G, McGeever A, de Morree A, Olivieri JE, Park M, Pisco AO, Ravikumar N, Salzman J, Stanley G, Swift M, Tan M, Tan W, Tarashansky AJ, Vanheusden R, Vorperian SK, Wang P, Wang S, Xing G, Xu C, Yosef N, Alcántara-Hernández M, Antony J, Chan CKF, Chang CA, Colville A, Crasta S, Culver R, Dethlefsen L, Ezran C, Gillich A, Hang Y, Ho PY, Irwin JC, Jang S, Kershner AM, Kong W, Kumar ME, Kuo AH, Leylek R, Liu S, Loeb GB, Lu WJ, Maltzman JS, Metzger RJ, de Morree A, Neuhöfer P, Perez K, Phansalkar R, Qi Z, Rao P, Raquer-McKay H, Sasagawa K, Scott B, Sinha R, Song H, Spencer SP, Swarup A, Swift M, Travaglini KJ, Trimm E, Veizades S, Vijayakumar S, Wang B, Wang W, Winkler J, Xie J, Yung AR, Artandi SE, Beachy PA, Clarke MF, Giudice LC, Huang FW, Huang KC, Idoyaga J, Kim SK, Krasnow M, Kuo CS, Nguyen P, Quake SR, Rando TA, Red-Horse K, Reiter J, Relman DA, Sonnenburg JL, Wang B, Wu A, Wu SM, Wyss-Coray T. PMID: 35549404; PMCID: PMC9812260.
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PubMed Mentions:
123 Fields:
Translation:
HumansCells
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Clonal lineage tracing reveals shared origin of conventional and plasmacytoid dendritic cells. Immunity. 2022 03 08; 55(3):405-422.e11.
Feng J, Pucella JN, Jang G, Alcántara-Hernández M, Upadhaya S, Adams NM, Khodadadi-Jamayran A, Lau CM, Stoeckius M, Hao S, Smibert P, Tsirigos A, Idoyaga J, Reizis B. PMID: 35180378; PMCID: PMC9344860.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Alveolar macrophages and epithelial cells: The art of living together. J Exp Med. 2021 10 04; 218(10).
Clements D, Idoyaga J. PMID: 34491265; PMCID: PMC8421265.
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PubMed Mentions:
1 Fields:
Translation:
Cells
-
Mass cytometry profiling of human dendritic cells in blood and tissues. Nat Protoc. 2021 10; 16(10):4855-4877.
Alcántara-Hernández M, Idoyaga J. PMID: 34480131; PMCID: PMC10538357.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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Gastric Mucosal Immune Profiling and Dysregulation in Idiopathic Gastroparesis. Clin Transl Gastroenterol. 2021 05 12; 12(5):e00349.
Gottfried-Blackmore A, Namkoong H, Adler E, Martin B, Gubatan J, Fernandez-Becker N, Clarke JO, Idoyaga J, Nguyen L, Habtezion A. PMID: 33979305; PMCID: PMC8132986.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Prolonged Codelivery of Hemagglutinin and a TLR7/8 Agonist in a Supramolecular Polymer-Nanoparticle Hydrogel Enhances Potency and Breadth of Influenza Vaccination. ACS Biomater Sci Eng. 2021 05 10; 7(5):1889-1899.
Roth GA, Saouaf OM, Smith AAA, Gale EC, Hernández MA, Idoyaga J, Appel EA. PMID: 33404236; PMCID: PMC8153386.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsPHPublic Health
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Skin dendritic cells in melanoma are key for successful checkpoint blockade therapy. J Immunother Cancer. 2021 01; 9(1).
Prokopi A, Tripp CH, Tummers B, Hornsteiner F, Spoeck S, Crawford JC, Clements DR, Efremova M, Hutter K, Bellmann L, Cappellano G, Cadilha BL, Kobold S, Boon L, Ortner D, Trajanoski Z, Chen S, de Gruijl TD, Idoyaga J, Green DR, Stoitzner P. PMID: 33408092; PMCID: PMC7789456.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Landscape of coordinated immune responses to H1N1 challenge in humans. J Clin Invest. 2020 11 02; 130(11):5800-5816.
Rahil Z, Leylek R, Schürch CM, Chen H, Bjornson-Hooper Z, Christensen SR, Gherardini PF, Bhate SS, Spitzer MH, Fragiadakis GK, Mukherjee N, Kim N, Jiang S, Yo J, Gaudilliere B, Affrime M, Bock B, Hensley SE, Idoyaga J, Aghaeepour N, Kim K, Nolan GP, McIlwain DR. PMID: 33044226; PMCID: PMC7598057.
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PubMed Mentions:
13 Fields:
Translation:
HumansCellsCTClinical Trials
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Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity. Cell Rep. 2020 09 22; 32(12):108180.
Leylek R, Alcántara-Hernández M, Granja JM, Chavez M, Perez K, Diaz OR, Li R, Satpathy AT, Chang HY, Idoyaga J. PMID: 32966789; PMCID: PMC7546547.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Injectable Hydrogels for Sustained Codelivery of Subunit Vaccines Enhance Humoral Immunity. ACS Cent Sci. 2020 Oct 28; 6(10):1800-1812.
Roth GA, Gale EC, Alcántara-Hernández M, Luo W, Axpe E, Verma R, Yin Q, Yu AC, Lopez Hernandez H, Maikawa CL, Smith AAA, Davis MM, Pulendran B, Idoyaga J, Appel EA. PMID: 33145416; PMCID: PMC7596866.
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PubMed Mentions:
40
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Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population. Cell Rep. 2019 12 10; 29(11):3736-3750.e8.
Leylek R, Alcántara-Hernández M, Lanzar Z, Lüdtke A, Perez OA, Reizis B, Idoyaga J. PMID: 31825848; PMCID: PMC6951814.
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PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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The versatile plasmacytoid dendritic cell: Function, heterogeneity, and plasticity. Int Rev Cell Mol Biol. 2019; 349:177-211.
Leylek R, Idoyaga J. PMID: 31759431.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Opposing T cell responses in experimental autoimmune encephalomyelitis. Nature. 2019 08; 572(7770):481-487.
Saligrama N, Zhao F, Sikora MJ, Serratelli WS, Fernandes RA, Louis DM, Yao W, Ji X, Idoyaga J, Mahajan VB, Steinmetz LM, Chien YH, Hauser SL, Oksenberg JR, Garcia KC, Davis MM. PMID: 31391585; PMCID: PMC7145319.
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PubMed Mentions:
83 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Nursing Markedly Protects Postpartum Mice From Stroke: Associated Central and Peripheral Neuroimmune Changes and a Role for Oxytocin. Front Neurosci. 2019; 13:609.
Stary CM, Xu L, Voloboueva LA, Alcántara-Hernández M, Arvola OJ, Idoyaga J, Giffard RG. PMID: 31354401; PMCID: PMC6637858.
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PubMed Mentions:
5
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The Nontoxic Cholera B Subunit Is a Potent Adjuvant for Intradermal DC-Targeted Vaccination. Front Immunol. 2018; 9:2212.
Antonio-Herrera L, Badillo-Godinez O, Medina-Contreras O, Tepale-Segura A, García-Lozano A, Gutierrez-Xicotencatl L, Soldevila G, Esquivel-Guadarrama FR, Idoyaga J, Bonifaz LC. PMID: 30319653; PMCID: PMC6171476.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Vaccination-induced skin-resident memory CD8+ T cells mediate strong protection against cutaneous melanoma. Oncoimmunology. 2018; 7(7):e1442163.
Gálvez-Cancino F, López E, Menares E, Díaz X, Flores C, Cáceres P, Hidalgo S, Chovar O, Alcántara-Hernández M, Borgna V, Varas-Godoy M, Salazar-Onfray F, Idoyaga J, Lladser A. PMID: 29900048; PMCID: PMC5993487.
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PubMed Mentions:
42 Fields:
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High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization. Immunity. 2017 12 19; 47(6):1037-1050.e6.
Alcántara-Hernández M, Leylek R, Wagar LE, Engleman EG, Keler T, Marinkovich MP, Davis MM, Nolan GP, Idoyaga J. PMID: 29221729; PMCID: PMC5738280.
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PubMed Mentions:
123 Fields:
Translation:
HumansAnimalsCells
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Ebola virus infection kinetics in chimeric mice reveal a key role of T cells as barriers for virus dissemination. Sci Rep. 2017 03 03; 7:43776.
Lüdtke A, Ruibal P, Wozniak DM, Pallasch E, Wurr S, Bockholt S, Gómez-Medina S, Qiu X, Kobinger GP, Rodríguez E, Günther S, Krasemann S, Idoyaga J, Oestereich L, Muñoz-Fontela C. PMID: 28256637; PMCID: PMC5335601.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Pseudogenization of the Secreted Effector Gene sseI Confers Rapid Systemic Dissemination of S. Typhimurium ST313 within Migratory Dendritic Cells. Cell Host Microbe. 2017 Feb 08; 21(2):182-194.
Carden SE, Walker GT, Honeycutt J, Lugo K, Pham T, Jacobson A, Bouley D, Idoyaga J, Tsolis RM, Monack D. PMID: 28182950; PMCID: PMC5325708.
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PubMed Mentions:
45 Fields:
Translation:
AnimalsCells
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Monocyte-derived dendritic cells enhance protection against secondary influenza challenge by controlling the switch in CD8+ T-cell immunodominance. Eur J Immunol. 2017 02; 47(2):345-352.
Cruz JL, Pérez-Girón JV, Lüdtke A, Gómez-Medina S, Ruibal P, Idoyaga J, Muñoz-Fontela C. PMID: 27859043; PMCID: PMC5324604.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Ebola Virus Disease Is Characterized by Poor Activation and Reduced Levels of Circulating CD16+ Monocytes. J Infect Dis. 2016 10 15; 214(suppl 3):S275-S280.
Lüdtke A, Ruibal P, Becker-Ziaja B, Rottstegge M, Wozniak DM, Cabeza-Cabrerizo M, Thorenz A, Weller R, Kerber R, Idoyaga J, Magassouba N, Gabriel M, Günther S, Oestereich L, Muñoz-Fontela C. PMID: 27521367.
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PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition. Immunity. 2016 Apr 19; 44(4):924-38.
Salmon H, Idoyaga J, Rahman A, Leboeuf M, Remark R, Jordan S, Casanova-Acebes M, Khudoynazarova M, Agudo J, Tung N, Chakarov S, Rivera C, Hogstad B, Bosenberg M, Hashimoto D, Gnjatic S, Bhardwaj N, Palucka AK, Brown BD, Brody J, Ginhoux F, Merad M. PMID: 27096321; PMCID: PMC4980762.
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PubMed Mentions:
524 Fields:
Translation:
AnimalsCells
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Reply to: "Subverting misconceptions about radiation therapy". Nat Immunol. 2016 Apr; 17(4):345-6.
Price JG, Idoyaga J, Merad M. PMID: 27002832.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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CDKN1A regulates Langerhans cell survival and promotes Treg cell generation upon exposure to ionizing irradiation. Nat Immunol. 2015 Oct; 16(10):1060-8.
Price JG, Idoyaga J, Salmon H, Hogstad B, Bigarella CL, Ghaffari S, Leboeuf M, Merad M. PMID: 26343536; PMCID: PMC4620552.
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PubMed Mentions:
59 Fields:
Translation:
AnimalsCells
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ESAT-6 Targeting to DEC205+ Antigen Presenting Cells Induces Specific-T Cell Responses against ESAT-6 and Reduces Pulmonary Infection with Virulent Mycobacterium tuberculosis. PLoS One. 2015; 10(4):e0124828.
Silva-Sánchez A, Meza-Pérez S, Flores-Langarica A, Donis-Maturano L, Estrada-García I, Calderón-Amador J, Hernández-Pando R, Idoyaga J, Steinman RM, Flores-Romo L. PMID: 25915045; PMCID: PMC4411092.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCellsPHPublic Health
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BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups. J Exp Med. 2015 Feb 09; 212(2):281.
Berres ML, Lim KP, Peters T, Price J, Takizawa H, Salmon H, Idoyaga J, Ruzo A, Lupo PJ, Hicks MJ, Shih A, Simko SJ, Abhyankar H, Chakraborty R, Leboeuf M, Beltrão M, Lira SA, Heym KM, Clausen BE, Bigley V, Collin M, Manz MG, McClain K, Merad M, Allen CE. PMID: 25646268; PMCID: PMC4322054.
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PubMed Mentions:
16 Fields:
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Activation of toll-like receptor-2 by endogenous matrix metalloproteinase-2 modulates dendritic-cell-mediated inflammatory responses. Cell Rep. 2014 Dec 11; 9(5):1856-1870.
Godefroy E, Gallois A, Idoyaga J, Merad M, Tung N, Monu N, Saenger Y, Fu Y, Ravindran R, Pulendran B, Jotereau F, Trombetta S, Bhardwaj N. PMID: 25466255; PMCID: PMC4336179.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance. EMBO Mol Med. 2014 Sep; 6(9):1191-204.
Flacher V, Tripp CH, Mairhofer DG, Steinman RM, Stoitzner P, Idoyaga J, Romani N. PMID: 25085878; PMCID: PMC4197865.
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PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups. J Exp Med. 2014 Apr 07; 211(4):669-83.
Berres ML, Lim KP, Peters T, Price J, Takizawa H, Salmon H, Idoyaga J, Ruzo A, Lupo PJ, Hicks MJ, Shih A, Simko SJ, Abhyankar H, Chakraborty R, Leboeuf M, Beltrão M, Lira SA, Heym KM, Bigley V, Collin M, Manz MG, McClain K, Merad M, Allen CE. PMID: 24638167; PMCID: PMC3978272.
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PubMed Mentions:
144 Fields:
Translation:
HumansAnimalsCells
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Targeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective Immunity. PLoS One. 2013; 8(6):e67453.
Matos I, Mizenina O, Lubkin A, Steinman RM, Idoyaga J. PMID: 23840706; PMCID: PMC3694010.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCellsPHPublic Health
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Induction of innate and adaptive immunity by delivery of poly dA:dT to dendritic cells. Nat Chem Biol. 2013 Apr; 9(4):250-6.
Barbuto S, Idoyaga J, Vila-Perelló M, Longhi MP, Breton G, Steinman RM, Muir TW. PMID: 23416331; PMCID: PMC3947612.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Specialized role of migratory dendritic cells in peripheral tolerance induction. J Clin Invest. 2013 Feb; 123(2):844-54.
Idoyaga J, Fiorese C, Zbytnuik L, Lubkin A, Miller J, Malissen B, Mucida D, Merad M, Steinman RM. PMID: 23298832; PMCID: PMC3561796.
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PubMed Mentions:
155 Fields:
Translation:
AnimalsCells
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Streamlined expressed protein ligation using split inteins. J Am Chem Soc. 2013 Jan 09; 135(1):286-92.
Vila-Perelló M, Liu Z, Shah NH, Willis JA, Idoyaga J, Muir TW. PMID: 23265282; PMCID: PMC3544275.
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PubMed Mentions:
42 Fields:
Translation:
Cells
-
Zinc finger transcription factor zDC is a negative regulator required to prevent activation of classical dendritic cells in the steady state. J Exp Med. 2012 Aug 27; 209(9):1583-93.
Meredith MM, Liu K, Kamphorst AO, Idoyaga J, Yamane A, Guermonprez P, Rihn S, Yao KH, Silva IT, Oliveira TY, Skokos D, Casellas R, Nussenzweig MC. PMID: 22851594; PMCID: PMC3428942.
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PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
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Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage. J Exp Med. 2012 Jun 04; 209(6):1153-65.
Meredith MM, Liu K, Darrasse-Jeze G, Kamphorst AO, Schreiber HA, Guermonprez P, Idoyaga J, Cheong C, Yao KH, Niec RE, Nussenzweig MC. PMID: 22615130; PMCID: PMC3371731.
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PubMed Mentions:
250 Fields:
Translation:
AnimalsCells
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Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice. J Exp Med. 2012 May 07; 209(5):1011-28.
Billiard F, Lobry C, Darrasse-Jèze G, Waite J, Liu X, Mouquet H, DaNave A, Tait M, Idoyaga J, Leboeuf M, Kyratsous CA, Burton J, Kalter J, Klinakis A, Zhang W, Thurston G, Merad M, Steinman RM, Murphy AJ, Yancopoulos GD, Aifantis I, Skokos D. PMID: 22547652; PMCID: PMC3348095.
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PubMed Mentions:
30 Fields:
Translation:
AnimalsCells
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Skin langerin+ dendritic cells transport intradermally injected anti-DEC-205 antibodies but are not essential for subsequent cytotoxic CD8+ T cell responses. J Immunol. 2012 Mar 01; 188(5):2146-55.
Flacher V, Tripp CH, Haid B, Kissenpfennig A, Malissen B, Stoitzner P, Idoyaga J, Romani N. PMID: 22291181; PMCID: PMC3288813.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Dendritic cell-targeted protein vaccines: a novel approach to induce T-cell immunity. J Intern Med. 2012 Feb; 271(2):183-92.
Trumpfheller C, Longhi MP, Caskey M, Idoyaga J, Bozzacco L, Keler T, Schlesinger SJ, Steinman RM. PMID: 22126373; PMCID: PMC3261312.
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PubMed Mentions:
78 Fields:
Translation:
HumansAnimalsCells
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Treml4, an Ig superfamily member, mediates presentation of several antigens to T cells in vivo, including protective immunity to HER2 protein. J Immunol. 2012 Feb 01; 188(3):1147-55.
Hemmi H, Zaidi N, Wang B, Matos I, Fiorese C, Lubkin A, Zbytnuik L, Suda K, Zhang K, Noda M, Kaisho T, Steinman RM, Idoyaga J. PMID: 22210914; PMCID: PMC3262937.
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PubMed Mentions:
29 Fields:
Translation:
AnimalsCellsPHPublic Health
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SnapShot: Dendritic Cells. Cell. 2011 Aug 19; 146(4):660-660.e2.
Idoyaga J, Steinman RM. PMID: 21854989.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A. Proc Natl Acad Sci U S A. 2011 Feb 08; 108(6):2384-9.
Idoyaga J, Lubkin A, Fiorese C, Lahoud MH, Caminschi I, Huang Y, Rodriguez A, Clausen BE, Park CG, Trumpfheller C, Steinman RM. PMID: 21262813; PMCID: PMC3038758.
View in:
PubMed Mentions:
134 Fields:
Translation:
AnimalsCells
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Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209(+) dendritic cells for immune T cell areas. Cell. 2010 Oct 29; 143(3):416-29.
Cheong C, Matos I, Choi JH, Dandamudi DB, Shrestha E, Longhi MP, Jeffrey KL, Anthony RM, Kluger C, Nchinda G, Koh H, Rodriguez A, Idoyaga J, Pack M, Velinzon K, Park CG, Steinman RM. PMID: 21029863; PMCID: PMC3150728.
View in:
PubMed Mentions:
306 Fields:
Translation:
AnimalsCells
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Targeting of antigens to skin dendritic cells: possibilities to enhance vaccine efficacy. Immunol Cell Biol. 2010 May-Jun; 88(4):424-30.
Romani N, Thurnher M, Idoyaga J, Steinman RM, Flacher V. PMID: 20368713; PMCID: PMC2907485.
View in:
PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCells
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Features of the dendritic cell lineage. Immunol Rev. 2010 Mar; 234(1):5-17.
Steinman RM, Idoyaga J. PMID: 20193008.
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PubMed Mentions:
109 Fields:
Translation:
HumansAnimalsCells
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Acute in vivo exposure to interferon-gamma enables resident brain dendritic cells to become effective antigen presenting cells. Proc Natl Acad Sci U S A. 2009 Dec 08; 106(49):20918-23.
Gottfried-Blackmore A, Kaunzner UW, Idoyaga J, Felger JC, McEwen BS, Bulloch K. PMID: 19906988; PMCID: PMC2791588.
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42 Fields:
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AnimalsCells
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Epidermal Langerhans cells rapidly capture and present antigens from C-type lectin-targeting antibodies deposited in the dermis. J Invest Dermatol. 2010 Mar; 130(3):755-62.
Flacher V, Tripp CH, Stoitzner P, Haid B, Ebner S, Del Frari B, Koch F, Park CG, Steinman RM, Idoyaga J, Romani N. PMID: 19890348; PMCID: PMC3140829.
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42 Fields:
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HumansAnimalsCells
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Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant. J Exp Med. 2009 Jul 06; 206(7):1589-602.
Longhi MP, Trumpfheller C, Idoyaga J, Caskey M, Matos I, Kluger C, Salazar AM, Colonna M, Steinman RM. PMID: 19564349; PMCID: PMC2715098.
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339 Fields:
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AnimalsCells
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A new triggering receptor expressed on myeloid cells (Trem) family member, Trem-like 4, binds to dead cells and is a DNAX activation protein 12-linked marker for subsets of mouse macrophages and dendritic cells. J Immunol. 2009 Feb 01; 182(3):1278-86.
Hemmi H, Idoyaga J, Suda K, Suda N, Kennedy K, Noda M, Aderem A, Steinman RM. PMID: 19155473; PMCID: PMC2843158.
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38 Fields:
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HumansAnimalsCells
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Antibody to Langerin/CD207 localizes large numbers of CD8alpha+ dendritic cells to the marginal zone of mouse spleen. Proc Natl Acad Sci U S A. 2009 Feb 03; 106(5):1524-9.
Idoyaga J, Suda N, Suda K, Park CG, Steinman RM. PMID: 19168629; PMCID: PMC2635812.
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66 Fields:
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AnimalsCells
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Cutting edge: langerin/CD207 receptor on dendritic cells mediates efficient antigen presentation on MHC I and II products in vivo. J Immunol. 2008 Mar 15; 180(6):3647-50.
Idoyaga J, Cheong C, Suda K, Suda N, Kim JY, Lee H, Park CG, Steinman RM. PMID: 18322168.
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80 Fields:
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AnimalsCells
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Generation and application of new rat monoclonal antibodies against synthetic FLAG and OLLAS tags for improved immunodetection. J Immunol Methods. 2008 Feb 29; 331(1-2):27-38.
Park SH, Cheong C, Idoyaga J, Kim JY, Choi JH, Do Y, Lee H, Jo JH, Oh YS, Im W, Steinman RM, Park CG. PMID: 18054954; PMCID: PMC2864634.
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39 Fields:
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AnimalsCells
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Production of monoclonal antibodies that recognize the extracellular domain of mouse langerin/CD207. J Immunol Methods. 2007 Jul 31; 324(1-2):48-62.
Cheong C, Idoyaga J, Do Y, Pack M, Park SH, Lee H, Kang YS, Choi JH, Kim JY, Bonito A, Inaba K, Yamazaki S, Steinman RM, Park CG. PMID: 17553520; PMCID: PMC2700064.
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30 Fields:
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HumansAnimalsCells
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Tumor cells prevent mouse dendritic cell maturation induced by TLR ligands. Cancer Immunol Immunother. 2007 Aug; 56(8):1237-50.
Idoyaga J, Moreno J, Bonifaz L. PMID: 17237931.
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14 Fields:
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AnimalsCells
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Innate NKT lymphocytes confer superior adaptive immunity via tumor-capturing dendritic cells. J Exp Med. 2005 Dec 05; 202(11):1507-16.
Liu K, Idoyaga J, Charalambous A, Fujii S, Bonito A, Mordoh J, Wainstok R, Bai XF, Liu Y, Steinman RM. PMID: 16330814; PMCID: PMC2213343.
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43 Fields:
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AnimalsCells
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Dendritic cells charged with apoptotic tumor cells induce long-lived protective CD4+ and CD8+ T cell immunity against B16 melanoma. J Immunol. 2003 Dec 01; 171(11):5940-7.
Goldszmid RS, Idoyaga J, Bravo AI, Steinman R, Mordoh J, Wainstok R. PMID: 14634105.
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71 Fields:
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AnimalsCells