Jose Suarez

Title(s)Assistant Professor In Residence, Family Medicine And Public Health
SchoolHealth Sciences
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    Collapse Biography 
    Collapse Awards and Honors
    Society of Toxicology, Occupational and Public Health Specialty Section (262 manuscripts reviewed)2012Paper of the Year 2012: Suarez-Lopez J et.al Lower acetylcholinesterase activity among children liv
    Faculty Mentor Program, UCSD2014  - 2015Outstanding Service as a Mentor
    JPB Foundation/Harvard University2014  - 2018JPB Environmental Health Fellow
    Western Societies of Medicine 2016First Annual Carmel Prize for Research Excellence
    California Environmental Contaminant Biomonitoring Program2017  - 2021Governor Appointment: Member of the Scientific Guidance Panel

    Collapse Overview 
    Collapse Overview
    My main research interests involve understanding the role of environmental contaminants on brain development and metabolic alterations of children and adults.

    I have conducted several studies of agricultural populations. I am the founding principal investigator of the NIH-funded Secondary Exposure to Pesticides among Children and Adolescents study (ESPINA – Estudio de la Exposicion Secundaria a Plaguicidas en Niños y Adolescentes). The ESPINA study is a longitudinal study established in 2008 aimed at understanding the associations of background exposures to pesticides with short- and long-term alterations in the development of children living in the agricultural county of Pedro Moncayo, Ecuador. This study was developed in response to the county health priorities of the county and has substantial community involvement. Our work focuses on neurobehavioral, mental health, endocrine, inflammatory, hemodynamic, respiratory, enzymatic and metabolomic changes associated with exposures to many classes of pesticides and persistent organic pollutants. Our work relies on geospatial determinants of exposure as well as blood and urinary markers of exposures to PFAS, PCBs, PBDE flame retardants, and many pesticides including insecticides (organochlorine, organophosphate, pyrethroid, carbamate, neonicotinoid), herbicides (glyphosate, 2,4-Dichlorophenoxyacetic acid), and fungicides (dithiocarbamate, quinone outside inhibitors, azoles). Additionally, we have a serum metabolomics suite, which coupled with targeted measures of agrochemicals (above), will help us estimate an agricultural exposome of participants in our study and provide novel information on the environment-metabolome-health associations.

    I am involved in community-based participatory processes in Ecuador in which we are collecting community health surveys and mental health screenings of large rural populations. In these activities, we are interested in answering questions that directly respond to the needs of the communities.

    I am also investigating within the Coronary Artery Risk Development in Young Adults (CARDIA) study the associations of persistent organic pollutants (i.e. organochlorine pesticides, PCBs, PBDEs, PBBs) and markers of oxidative stress with and alterations in glucose and lipid metabolism, and subclinical heart disease in middle age adults.

    I lead the Nuts and Olestra for reduction of Persistent Organic Pollutants(NO-POPs) trial which is testing the effects of dietary interventions on enhancing the excretion of Persistent Organic Pollutants, such as PCBs, PBDE flame retardants and organochlorine pesticides among older adults in San Diego, CA.

    I was appointed as a member of the Scientific Guidance Panel to the California Environmental Contaminant Biomonitoring Program (Biomonitoring California) by Governor Edmond Brown Jr. of California for the period 4/2017 – 3/2021. I am also a first-cohort JPB Fellow of Environmental Health at Havard University.

    Collapse Research 
    Collapse Research Activities and Funding
    Pesticides, Perfluorinated Compounds, and the Development of Adolescents in Agricultural Communities
    Children's Health Exposure Analysis Resource - NIEHS 2018-1599Jul 1, 2019
    Role: Principal Investigator
    Role Description: The goals of this project are to are to assess whether herbicides, fungicides, insecticides and perfluorinated substances (PFAS) can affect adolescent health in outcomes including metabolomic patterns, neurobehavioral performance, mental health and body composition among participants of the ESPINA study
    Pesticide Exposures and Risks of Adverse Motor and Cognitive System Health Effects Among Latino Residents of Imperial Valley, California
    CTRI Pilot Grant Program Apr 1, 2017 - Mar 31, 2018
    Role: Co-Investigator
    GLOBAL HEALTH INSTITUTE, UCSD Jul 1, 2016 - Jun 30, 2018
    Role: Principal Investigator
    The ESPINA Study Follow-up Examination in 2016: Environmental Pollutants and Child/Adolescent Development
    NIH/NIEHS R01ES025792Apr 1, 2016 - Mar 31, 2021
    Role: Principal Investigator
    Pesticides and Mental Health among Adolescents in Ecuadorian Agricultural Communities
    NIH/NIEHS R21ES026084Sep 1, 2015 - Aug 31, 2017
    Role: Principal Investigator
    Nuts and Olestra for Persistent Organic Pollutant Reduction (NO-POPs) Trial
    JPB Foundation - JPB Environmental Health Program Oct 1, 2014 - Feb 28, 2018
    Role: Principal Investigator
    Environmental Pollutants, Anxiety and Depression in Adolescents
    FPM PILOT GRANT PROGRAM Aug 1, 2014 - Jul 31, 2016
    Role: Principal investigaro
    Effects of Secondary Occupational Pesticide Exposure on Childhood Growth
    CDC/NIOSH R36OH009402Sep 30, 2007 - May 31, 2009
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Eskenazi B, Etzel RA, Sripada K, Cairns MR, Hertz-Picciotto I, Kordas K, Machado Torres JP, Mielke HW, Oulhote Y, Quirós-Alcalá L, Suárez-López JR, Zlatnik MG. The International Society for Children's Health and the Environment Commits to Reduce Its Carbon Footprint to Safeguard Children's Health. Environ Health Perspect. 2020 Jan; 128(1):14501. PMID: 31909653.
      View in: PubMed
    2. Friedman E, Hazlehurst MF, Loftus C, Karr C, McDonald KN, Suarez-Lopez JR. Residential proximity to greenhouse agriculture and neurobehavioral performance in Ecuadorian children. Int J Hyg Environ Health. 2020 01; 223(1):220-227. PMID: 31607631.
      View in: PubMed
    3. Suarez-Lopez JR, Hood N, Suárez-Torres J, Gahagan S, Gunnar MR, López-Paredes D. Associations of acetylcholinesterase activity with depression and anxiety symptoms among adolescents growing up near pesticide spray sites. Int J Hyg Environ Health. 2019 08; 222(7):981-990. PMID: 31202795.
      View in: PubMed
    4. Suarez-Lopez JR, Amchich F, Murillo J, Denenberg J. Blood pressure after a heightened pesticide spray period among children living in agricultural communities in Ecuador. Environ Res. 2019 08; 175:335-342. PMID: 31150932.
      View in: PubMed
    5. Suarez-Lopez JR, Gross MD, Lee DH. Summary data of serum concentrations of 32 persistent organic pollutants in young adults in relation to summary scores of persistent organic pollutants. Data Brief. 2019 Apr; 23:103720. PMID: 31193752.
      View in: PubMed
    6. Suarez-Lopez JR, Clemesha CG, Porta M, Gross MD, Lee DH. Organochlorine pesticides and polychlorinated biphenyls (PCBs) in early adulthood and blood lipids over a 23-year follow-up. Environ Toxicol Pharmacol. 2019 Feb; 66:24-35. PMID: 30594847.
      View in: PubMed
    7. Suarez-Lopez JR, Hong V, McDonald KN, Suarez-Torres J, López D, De La Cruz F. Home proximity to flower plantations and higher systolic blood pressure among children. Int J Hyg Environ Health. 2018 09; 221(8):1077-1084. PMID: 30131222.
      View in: PubMed
    8. Suarez-Lopez JR, Butcher CR, Gahagan S, Checkoway H, Alexander BH, Al-Delaimy WK. Acetylcholinesterase activity and time after a peak pesticide-use period among Ecuadorian children. Int Arch Occup Environ Health. 2018 02; 91(2):175-184. PMID: 29026987.
      View in: PubMed
    9. Suárez-Torres J, Suárez-López JR, López-Paredes D, Morocho H, Cachiguango-Cachiguango LE, Dellai W. Agroecology and Health: Lessons from Indigenous Populations. Curr Environ Health Rep. 2017 06; 4(2):244-251. PMID: 28429300.
      View in: PubMed
    10. Suarez-Lopez JR, Checkoway H, Jacobs DR, Al-Delaimy WK, Gahagan S. Potential short-term neurobehavioral alterations in children associated with a peak pesticide spray season: The Mother's Day flower harvest in Ecuador. Neurotoxicology. 2017 May; 60:125-133. PMID: 28188819.
      View in: PubMed
    11. Suarez-Lopez JR, Lee DH, Porta M, Steffes MW, Jacobs DR. Persistent organic pollutants in young adults and changes in glucose related metabolism over a 23-year follow-up. Environ Res. 2015 Feb; 137:485-94. PMID: 25706918.
      View in: PubMed
    12. Suarez-Lopez JR, Himes JH, Jacobs DR, Alexander BH, Gunnar MR. Acetylcholinesterase activity and neurodevelopment in boys and girls. Pediatrics. 2013 Dec; 132(6):e1649-58. PMID: 24249815.
      View in: PubMed
    13. Suarez-Lopez JR, Jacobs DR, Himes JH, Alexander BH. Acetylcholinesterase activity, cohabitation with floricultural workers, and blood pressure in Ecuadorian children. Environ Health Perspect. 2013 May; 121(5):619-24. PMID: 23359481.
      View in: PubMed
    14. Suarez-Lopez JR, Jacobs DR, Himes JH, Alexander BH, Lazovich D, Gunnar M. Lower acetylcholinesterase activity among children living with flower plantation workers. Environ Res. 2012 Apr; 114:53-9. PMID: 22405996.
      View in: PubMed
    15. Gross MD, Bielinski SJ, Suarez-Lopez JR, Reiner AP, Bailey K, Thyagarajan B, Carr JJ, Duprez DA, Jacobs DR. Circulating soluble intercellular adhesion molecule 1 and subclinical atherosclerosis: the Coronary Artery Risk Development in Young Adults Study. Clin Chem. 2012 Feb; 58(2):411-20. PMID: 22179741.
      View in: PubMed
    16. Zhu N, Suarez-Lopez JR, Sidney S, Sternfeld B, Schreiner PJ, Carnethon MR, Lewis CE, Crow RS, Bouchard C, Haskell WL, Jacobs DR. Longitudinal examination of age-predicted symptom-limited exercise maximum HR. Med Sci Sports Exerc. 2010 Aug; 42(8):1519-27. PMID: 20639723.
      View in: PubMed