David Kunkel

Title(s)	Associate Clinical Professor, Medicine
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
ORCID	0000-0001-7319-8677
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Biography

Education and Training

University of New Mexico	Medical Degree	2008	Medicine
Cedars-Sinai Medical Center	Internship & Residency	2011	Internal Medicine
UCLA	Fellowship	2014	Gastroenterology

Overview

Websites

	UC San Diego Clinical Profile
	Dr. Kunkel's GI Health Foundation Profile

In The News

	AGA/ASGE Joint Session: 2024 Updates in Gastroenterology for the Hepatologist (11/17/2024)
	If You Need to Poop Right After Eating, Here’s Why (11/08/2024)
	Evoke Pharma to Host First Key Opinion Leader Webinar on Healthcare Resource Utilization Data Related to Gastroparesis and its Treatment (06/14/2023)
	The Rogue Theory That Gravity Causes IBS (03/15/2023)
	Real-World Healthcare Utilization Study Comparing GIMOTI® and Oral Metoclopramide at the Digestive Disease Week Plenary Session (02/21/2023)
	Real-world study compares diabetic gastroparesis patient utilization of healthcare resources before and after initiation of GIMOTI (01/18/2023)
	New Clinic Provides Comprehensive Care for Digestive Diseases in Westfield UTC (04/18/2022)
	TRIAL BY JURY: Irritable Bowel Syndrome (10/27/2019)
	How to Beat Belly Bloat Once and for All, According to a Gut Expert (07/27/2019)
	DDW News: Coding and billing experts will share best practices (05/17/2019)
	The Stinky Side Effect of Your High Protein Diet (02/07/2019)
	Stomach wearable could replace the need for invasive probes (04/02/2018)
	Tummy Tech Tracks Electrical Activity for Signs of Indigestion (03/30/2018)
	Rx: Wear this on your tummy and call me in the morning (03/27/2018)
	UCSD researchers develop wearable, 24-hour GI tract monitor (03/26/2018)
	A wearable system to monitor the stomach's activity throughout the day (03/22/2018)

Research

Research Activities and Funding

Inverse Methods for Spatiotemporal Characterization of Gastric Electrical Activity and its Association with Upper GI Symptoms from Cutaneous Multi-electrode Recordings
NIH R03EB031189May 1, 2021 - Feb 28, 2023
Role: Co-Investigator

Immunoprofiling for identifying biomarkers in celiac disease
NIH R21AI149636Feb 12, 2020 - Jan 31, 2022
Role: Co-Investigator

An Innovative Rehabilitation Approach for Women with Anal Incontinence
NIH R01HD088688Sep 1, 2017 - Jun 30, 2022
Role: Co-Investigator

ORNG Applications

Clinical Trials

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Magnetic sphincter augmentation: A promising alternative to fundoplication for preserving lung function and protecting against chronic lung transplant rejection. Transplantation Reports. 2024; 9(3):1-6. Huang EY, Afshar K, Golts E, Broderick RC, Spurzem GJ, Chung D, Holmgren J, Sandler BJ, Jacobsen GR, Kunkel DC, Horgan S. View Publication.
Intestinal Permeability, Irritable Bowel Syndrome with Constipation, and the Role of Sodium-Hydrogen Exchanger Isoform 3 (NHE3). Clin Exp Gastroenterol. 2024; 17:173-183. Lacy BE, Rosenbaum D, Edelstein S, Kozuka K, Williams LA, Kunkel DC. PMID: 38860153; PMCID: PMC11164200.

View in: PubMed Mentions:
A Multidisciplinary Assessment of ChatGPT's Knowledge of Amyloidosis: Observational Study. JMIR Cardio. 2024 Apr 19; 8:e53421. King RC, Samaan JS, Yeo YH, Peng Y, Kunkel DC, Habib AA, Ghashghaei R. PMID: 38640472; PMCID: PMC11069089.

View in: PubMed Mentions: 2
Exploring the Gut-Brain Connection in Gastroparesis With Autonomic and Gastric Myoelectric Monitoring. IEEE Trans Biomed Eng. 2023 12; 70(12):3342-3353. Subramanian S, Kunkel DC, Nguyen L, Coleman TP. PMID: 37310840.

View in: PubMed Mentions: 1 Fields:
Bio Biomedical Engineering
Translation:Humans
Exploring the aperiodic nature of parasympathetic activity during sleep in idiopathic gastroparesis. Annu Int Conf IEEE Eng Med Biol Soc. 2023 07; 2023:1-4. Subramanian S, Kunkel DC, Coleman TP. PMID: 38083696.

View in: PubMed Mentions: Fields:
Bio Biomedical Engineering
Translation:Humans
Tolerability and Feasibility of the Upper Esophageal Sphincter Assist Device in Preventing Acute and Chronic Allograft Rejection Among Lung Transplant Recipients. J Clin Gastroenterol. 2023 07 01; 57(6):574-577. Iyer NR, Afshar K, Golts E, Onaitis MW, Kafi A, Yung GL, Kunkel DC. PMID: 35703261.

View in: PubMed Mentions: Fields:
Gas Gastroenterology
Translation:Humans
Optimizing the Utility of Anorectal Manometry for Diagnosis and Therapy: A Roundtable Review and Recommendations. Clin Gastroenterol Hepatol. 2023 10; 21(11):2727-2739.e1. Rao SSC, Ahuja NK, Bharucha AE, Brenner DM, Chey WD, Deutsch JK, Kunkel DC, Moshiree B, Neshatian L, Reveille RM, Sayuk GS, Shapiro JM, Shah ED, Staller K, Wexner SD, Baker JR. PMID: 37302444; PMCID: PMC10542660.

View in: PubMed Mentions: 1 Fields:
Gas Gastroenterology
Translation:Humans
Principles and clinical methods of body surface gastric mapping: Technical review. Neurogastroenterol Motil. 2023 10; 35(10):e14556. O'Grady G, Varghese C, Schamberg G, Calder S, Du P, Xu W, Tack J, Daker C, Mousa H, Abell TL, Parkman HP, Ho V, Bradshaw LA, Hobson A, Andrews CN, Gharibans AA, BSGM Working Group. PMID: 36989183; PMCID: PMC10524901.

View in: PubMed Mentions: 11 Fields:
Gas Gastroenterology Neu Neurology
Translation:Humans
Esophageal Inlet Patch: A Clinically Significant Entity in Advanced Pulmonary Disease and Lung Transplant Rejection. Foregut. 2023; 3(1):12-19. Iyer NR, Afshar K, Joshua J, Golts E, Yung GL, Kafi A, Conrad DJ, Kunkel DC. View Publication.
Efficacy and safety of olorinab, a full agonist of the cannabinoid receptor 2, for the treatment of abdominal pain in patients with irritable bowel syndrome: Results from a phase 2b randomized placebo-controlled trial (CAPTIVATE). Neurogastroenterol Motil. 2023 05; 35(5):e14539. Chang L, Cash BD, Lembo A, Kunkel DC, English BA, Lindstrom B, Gu G, Skare S, Gilder K, Turner S, Cataldi F, Lipkis D, Tack J. PMID: 36740814.

View in: PubMed Mentions: 5 Fields:
Gas Gastroenterology Neu Neurology
Translation:Humans CTClinical Trials
Robust Regression and Optimal Transport Methods to Predict Gastrointestinal Disease Etiology From High Resolution EGG and Symptom Severity. IEEE Trans Biomed Eng. 2022 11; 69(11):3313-3325. Agrusa AS, Kunkel DC, Coleman TP. PMID: 35439119.

View in: PubMed Mentions: 4 Fields:
Bio Biomedical Engineering
Translation:Humans
Weight loss outcomes are not compromised in bariatric patients using cannabis. Surg Endosc. 2023 03; 37(3):2194-2201. Huang EY, Broderick RC, Li JZ, Serra JL, Ahuja P, Wu S, Genz M, Grunvald E, Kunkel DC, Sandler BJ, Horgan S, Jacobsen GR. PMID: 35861881.

View in: PubMed Mentions: Fields:
Dia Diagnostic Imaging Gas Gastroenterology Gen General Surgery
Miniaturized wireless gastric pacing via inductive power transfer with non-invasive monitoring using cutaneous Electrogastrography. Bioelectron Med. 2021 Aug 24; 7(1):12. Perley A, Roustaei M, Aguilar-Rivera M, Kunkel DC, Hsiai TK, Coleman TP, Abiri P. PMID: 34425917; PMCID: PMC8383397.

View in: PubMed Mentions: 1
An Adhesive‐Integrated Stretchable Silver‐Silver Chloride Electrode Array for Unobtrusive Monitoring of Gastric Neuromuscular Activity. Advanced Materials Technologies. 2021; 6(5):2001229. Kurniawan JF, Tjhia B, Wu VCM, Shin A, Sit NLJ, Pham T, Li CR, Kumar R, Aguilar-Rivera M, Lerman I, Kunkel DC, Coleman TP. View Publication.
More beads, more peristaltic reserve, better outcomes: factors predicting postoperative dysphagia after magnetic sphincter augmentation. Surg Endosc. 2021 09; 35(9):5295-5302. Dominguez-Profeta R, Cheverie JN, Blitzer RR, Lee AM, McClain L, Broderick RC, Sandler BJ, Jacobsen GR, Horgan S, Kunkel DC. PMID: 33128078.

View in: PubMed Mentions: 3 Fields:
Dia Diagnostic Imaging Gas Gastroenterology Gen General Surgery
Translation:Humans
Endoscopic ultrasound: a powerful tool to modify treatment algorithms in opioid-induced achalasia. Surg Endosc. 2021 08; 35(8):4585-4594. Lee AM, Holmgren J, Broderick RC, Cheverie JN, Sandler BJ, Jacobsen GR, Kwong WT, Kunkel DC, Horgan S. PMID: 32845401.

View in: PubMed Mentions: Fields:
Dia Diagnostic Imaging Gas Gastroenterology Gen General Surgery
Translation:Humans
Robust Methods to Detect Abnormal Initiation in the Gastric Slow Wave from Cutaneous Recordings. Annu Int Conf IEEE Eng Med Biol Soc. 2020 07; 2020:225-231. Agrusa AS, Allegra AB, Kunkel DC, Coleman TP. PMID: 33017970.

View in: PubMed Mentions: 2 Fields:
Bio Biomedical Engineering
Translation:Humans
Morphology of the Esophageal Hiatus: Is It Different in 3 Types of Hiatus Hernias? J Neurogastroenterol Motil. 2020 Jan 30; 26(1):51-60. Kumar D, Zifan A, Ghahremani G, Kunkel DC, Horgan S, Mittal RK. PMID: 31677612; PMCID: PMC6955188.

View in: PubMed Mentions: 9
Loop analysis of the anal sphincter complex in fecal incontinent patients using functional luminal imaging probe. Am J Physiol Gastrointest Liver Physiol. 2020 01 01; 318(1):G66-G76. Zifan A, Mittal RK, Kunkel DC, Swartz J, Barr G, Tuttle LJ. PMID: 31736339; PMCID: PMC6985842.

View in: PubMed Mentions: 4 Fields:
Gas Gastroenterology Phy Physiology
Translation:Humans
Bayesian inverse methods for spatiotemporal characterization of gastric electrical activity from cutaneous multi-electrode recordings. PLoS One. 2019; 14(10):e0220315. Allegra AB, Gharibans AA, Schamberg GE, Kunkel DC, Coleman TP. PMID: 31609972; PMCID: PMC6791545.

View in: PubMed Mentions: 7 Fields:
Med Medicine (General)Sci Science
Translation:Humans
A Deep Convolutional Neural Network Approach to Classify Normal and Abnormal Gastric Slow Wave Initiation From the High Resolution Electrogastrogram. IEEE Trans Biomed Eng. 2020 03; 67(3):854-867. Agrusa AS, Gharibans AA, Allegra AA, Kunkel DC, Coleman TP. PMID: 31199249.

View in: PubMed Mentions: 5 Fields:
Bio Biomedical Engineering
Translation:Humans
Spatial Patterns From High-Resolution Electrogastrography Correlate With Severity of Symptoms in Patients With Functional Dyspepsia and Gastroparesis. Clin Gastroenterol Hepatol. 2019 12; 17(13):2668-2677. Gharibans AA, Coleman TP, Mousa H, Kunkel DC. PMID: 31009794.

View in: PubMed Mentions: 49 Fields:
Gas Gastroenterology
Translation:Humans
Murky Waters for Diagnosis of Gastroparesis. Clin Gastroenterol Hepatol. 2019 08; 17(9):1724-1725. Kunkel DC, Clarke JO. PMID: 30978538.

View in: PubMed Mentions: 3 Fields:
Gas Gastroenterology
Translation:Humans
High-frequency ultrasound imaging of the anal sphincter muscles in normal subjects and patients with fecal incontinence. Neurogastroenterol Motil. 2019 04; 31(4):e13537. Ledgerwood-Lee M, Zifan A, Kunkel DC, Sah R, Mittal RK. PMID: 30680849; PMCID: PMC6405312.

View in: PubMed Mentions: 4 Fields:
Gas Gastroenterology Neu Neurology
Translation:Humans
Artifact Rejection Methodology Enables Continuous, Noninvasive Measurement of Gastric Myoelectric Activity in Ambulatory Subjects. Sci Rep. 2018 03 22; 8(1):5019. Gharibans AA, Smarr BL, Kunkel DC, Kriegsfeld LJ, Mousa HM, Coleman TP. PMID: 29568042; PMCID: PMC5864836.

View in: PubMed Mentions: 25 Fields:
Sci Science
Translation:Humans
High-Resolution Electrogastrogram: A Novel, Noninvasive Method for Determining Gastric Slow-Wave Direction and Speed. IEEE Trans Biomed Eng. 2017 04; 64(4):807-815. Gharibans AA, Kim S, Kunkel D, Coleman TP. PMID: 27305668; PMCID: PMC5474202.

View in: PubMed Mentions: 30 Fields:
Bio Biomedical Engineering
Acute Liver Failure Following One Year of Daily Consumption of a Sugar-Free Energy Drink. ACG Case Rep J. 2014 Jul; 1(4):214-6. Huang B, Kunkel D, Kabany ME. PMID: 26157880; PMCID: PMC4435335.

View in: PubMed Mentions: 7
Successful gastric volvulus reduction and gastropexy using a dual endoscope technique. Case Rep Med. 2014; 2014:136381. Jamil LH, Huang BL, Kunkel DC, Jayaraman V, Soffer EE. PMID: 24563653; PMCID: PMC3915862.

View in: PubMed Mentions: 12
Using a stent extractor for a case of pill impaction: a novel approach. Gastrointest Endosc. 2014 Jan; 79(1):185-6. Huang BL, Kunkel DC, So LY, Conklin JL. PMID: 24342600.

View in: PubMed Mentions: Fields:
Dia Diagnostic Imaging Gas Gastroenterology The Therapeutics
Translation:Humans
Underwater hot and cold snare polypectomy can be safely executed during water exchange colonoscopy. J Interv Gastroenterol. 2013 7; 3(3):104-106. Ocampo LH, Kunkel DC, Yen A, Tan CR, Leung JW, Leung FW. PMID: 24478929; PMCID: PMC3895149.

View in: PubMed Mentions:
A novel application of the water exchange method in the treatment of sigmoid volvulus: a report of two cases. J Interv Gastroenterol. 2013 1; 3(1):28-30. Tan C, Kunkel D, Ocampo LH, Sanmiguel CP, Karsan S, Cohen H, Leung FW. PMID: 24147224; PMCID: PMC3791537.

View in: PubMed Mentions:
Importance of diarrhea in evaluating constipation in irritable bowel syndrome clinical studies. J Clin Gastroenterol. 2011 Oct; 45(9):790-3. Basseri RJ, Kunkel D, Low K, Conklin JL, Pimentel M. PMID: 21301356.

View in: PubMed Mentions: 2 Fields:
Gas Gastroenterology
Translation:Humans
Efficacy of the glucagon-like peptide-1 agonist exenatide in the treatment of short bowel syndrome. Neurogastroenterol Motil. 2011 Aug; 23(8):739-e328. Kunkel D, Basseri B, Low K, Lezcano S, Soffer EE, Conklin JL, Mathur R, Pimentel M. PMID: 21557790.

View in: PubMed Mentions: 19 Fields:
Gas Gastroenterology Neu Neurology
Translation:Humans
Acute and chronic histological changes of the small bowel secondary to C. jejuni infection in a rat model for post-infectious IBS. Dig Dis Sci. 2011 Sep; 56(9):2575-84. Morales W, Pimentel M, Hwang L, Kunkel D, Pokkunuri V, Basseri B, Low K, Wang H, Conklin JL, Chang C. PMID: 21409374.

View in: PubMed Mentions: 11 Fields:
Gas Gastroenterology
Translation:Animals Cells
Methane on breath testing is associated with constipation: a systematic review and meta-analysis. Dig Dis Sci. 2011 Jun; 56(6):1612-8. Kunkel D, Basseri RJ, Makhani MD, Chong K, Chang C, Pimentel M. PMID: 21286935.

View in: PubMed Mentions: 64 Fields:
Gas Gastroenterology
Translation:Humans
The Pleural-based Mass: A Case Report and Review of the Literature. Proceedings of UCLA Healthcare. 2010; 14:1-3. Kunkel DC, Cheng ET. View Publication.
Basaloid Squamous Cell Carcinoma of the Upper Aerodigestive Tract: A Case Report and Review of the Literature. Proceedings of UCLA Healthcare. 2010; 14:1-3. Kunkel DC, Cheng ET. View Publication.
H19 imprinting control region methylation requires an imprinted environment only in the male germ line. Mol Cell Biol. 2010 Mar; 30(5):1108-15. Gebert C, Kunkel D, Grinberg A, Pfeifer K. PMID: 20038532; PMCID: PMC2820884.

View in: PubMed Mentions: 20 Fields:
Cel Cell Biology Mol Molecular Biology
Translation:Animals Cells
Characteristics of intestinal metaplasia in the gastric cardia. Am J Gastroenterol. 1999 Mar; 94(3):622-7. El-Serag HB, Sonnenberg A, Jamal MM, Kunkel D, Crooks L, Feddersen RM. PMID: 10086641.

View in: PubMed Mentions: 15 Fields:
Gas Gastroenterology
Translation:Humans