Benjamin Zaepfel

Title(s)Postdoctoral Scholar, Cellular and Molecular Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Counter-regulation of RNA stability by UPF1 and TDP43. bioRxiv. 2024 Feb 15. Gomez N, Hsieh C, Li X, Dykstra M, Waksmacki J, Altheim C, Bechar Y, Klim J, Zaepfel B, Rothstein J, Tank EE, Barmada SJ. PMID: 38352350; PMCID: PMC10862862.
      View in: PubMed   Mentions:
    2. Nuclear Pore Dysfunction in Neurodegeneration. Neurotherapeutics. 2022 07; 19(4):1050-1060. Spead O, Zaepfel BL, Rothstein JD. PMID: 36070178; PMCID: PMC9587172.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    3. Nuclear RNA binding regulates TDP-43 nuclear localization and passive nuclear export. Cell Rep. 2022 07 19; 40(3):111106. Duan L, Zaepfel BL, Aksenova V, Dasso M, Rothstein JD, Kalab P, Hayes LR. PMID: 35858577; PMCID: PMC9345261.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    4. Polyadenylated RNA and RNA-Binding Proteins Exhibit Unique Response to Hyperosmotic Stress. Front Cell Dev Biol. 2021; 9:809859. Zaepfel BL, Rothstein JD. PMID: 34970554; PMCID: PMC8712688.
      View in: PubMed   Mentions:
    5. Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS. Sci Transl Med. 2021 07 28; 13(604). Coyne AN, Baskerville V, Zaepfel BL, Dickson DW, Rigo F, Bennett F, Lusk CP, Rothstein JD. PMID: 34321318; PMCID: PMC9022198.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    6. RNA Is a Double-Edged Sword in ALS Pathogenesis. Front Cell Neurosci. 2021; 15:708181. Zaepfel BL, Rothstein JD. PMID: 34349625; PMCID: PMC8326408.
      View in: PubMed   Mentions: 10  
    7. UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction. Cell Rep. 2021 03 30; 34(13):108925. Zaepfel BL, Zhang Z, Maulding K, Coyne AN, Cheng W, Hayes LR, Lloyd TE, Sun S, Rothstein JD. PMID: 33789100; PMCID: PMC8063722.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    8. G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD. Neuron. 2020 09 23; 107(6):1124-1140.e11. Coyne AN, Zaepfel BL, Hayes L, Fitchman B, Salzberg Y, Luo EC, Bowen K, Trost H, Aigner S, Rigo F, Yeo GW, Harel A, Svendsen CN, Sareen D, Rothstein JD. PMID: 32673563; PMCID: PMC8077944.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    9. Post-transcriptional Inhibition of Hsc70-4/HSPA8 Expression Leads to Synaptic Vesicle Cycling Defects in Multiple Models of ALS. Cell Rep. 2017 Oct 03; 21(1):110-125. Coyne AN, Lorenzini I, Chou CC, Torvund M, Rogers RS, Starr A, Zaepfel BL, Levy J, Johannesmeyer J, Schwartz JC, Nishimune H, Zinsmaier K, Rossoll W, Sattler R, Zarnescu DC. PMID: 28978466; PMCID: PMC5679478.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    10. Failure to Deliver and Translate-New Insights into RNA Dysregulation in ALS. Front Cell Neurosci. 2017; 11:243. Coyne AN, Zaepfel BL, Zarnescu DC. PMID: 28860970; PMCID: PMC5562674.
      View in: PubMed   Mentions: 22  
    11. Fragile X protein mitigates TDP-43 toxicity by remodeling RNA granules and restoring translation. Hum Mol Genet. 2015 Dec 15; 24(24):6886-98. Coyne AN, Yamada SB, Siddegowda BB, Estes PS, Zaepfel BL, Johannesmeyer JS, Lockwood DB, Pham LT, Hart MP, Cassel JA, Freibaum B, Boehringer AV, Taylor JP, Reitz AB, Gitler AD, Zarnescu DC. PMID: 26385636; PMCID: PMC5007633.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
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