Alberto Hayek

Title(s)	Senate Emeritus, Pediatrics
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Research

research activities and funding

SMALL INSTRUMENTATION GRANT
NIH/NIDDK S15DK046038Aug 1, 1992 - Jul 31, 1993
Role: Principal Investigator

SMALL INSTRUMENTATION GRANT
NIH/NIDDK S15DK044705Aug 1, 1991 - Jul 31, 1992
Role: Principal Investigator

SMALL INSTRUMENTATION GRANT
NIH/NIDDK S15DK043427Jul 15, 1990 - Jun 30, 1991
Role: Principal Investigator

ISLET TRANSPLANTATION IN EXPERIMENTAL DIABETES
NIH/NIDDK R01DK039087Dec 1, 1988 - Nov 30, 1995
Role: Principal Investigator

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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sRNA-seq analysis of human embryonic stem cells and definitive endoderm reveals differentially expressed microRNAs and novel IsomiRs with distinct targets. Stem Cells. 2014 Sep; 32(9):2360-72. Hinton A, Hunter SE, Afrikanova I, Jones GA, Lopez AD, Fogel GB, Hayek A, King CC. PMID: 24805944.

View in: PubMed Mentions: 19 Fields:
Cel Cell Biology Emb Embryology
Translation:Humans Cells
Isolation, culture, and imaging of human fetal pancreatic cell clusters. J Vis Exp. 2014 May 18; (87). Lopez AD, Kayali AG, Hayek A, King CC. PMID: 24895054; PMCID: PMC4193289.

View in: PubMed Mentions: 1 Fields:
Bio Biology Med Medicine (General)
Translation:Humans Animals
Is stage-specific embryonic antigen 4 a marker for human ductal stem/progenitor cells? Biores Open Access. 2012 Aug; 1(4):184-91. Afrikanova I, Kayali A, Lopez A, Hayek A. PMID: 23515456; PMCID: PMC3559232.

View in: PubMed Mentions: 3
The SDF-1α/CXCR4 axis is required for proliferation and maturation of human fetal pancreatic endocrine progenitor cells. PLoS One. 2012; 7(6):e38721. Kayali AG, Lopez AD, Hao E, Hinton A, Hayek A, King CC. PMID: 22761699; PMCID: PMC3382144.

View in: PubMed Mentions: 10 Fields:
Med Medicine (General)Sci Science
Translation:Humans Animals Cells
Inhibitors of Src and focal adhesion kinase promote endocrine specification: impact on the derivation of β-cells from human pluripotent stem cells. J Biol Chem. 2011 Oct 14; 286(41):36042-36052. Afrikanova I, Yebra M, Simpkinson M, Xu Y, Hayek A, Montgomery A. PMID: 21852242; PMCID: PMC3195622.

View in: PubMed Mentions: 12 Fields:
Bio Biochemistry
Translation:Humans Cells
Impact of integrin-matrix interaction and signaling on insulin gene expression and the mesenchymal transition of human beta-cells. J Cell Physiol. 2010 Jul; 224(1):101-11. Kaido TJ, Yebra M, Kaneto H, Cirulli V, Hayek A, Montgomery AM. PMID: 20232313.

View in: PubMed Mentions: 13 Fields:
Cel Cell Biology Phy Physiology
Translation:Humans Cells
A distinct microRNA signature for definitive endoderm derived from human embryonic stem cells. Stem Cells Dev. 2010 Jun; 19(6):797-807. Hinton A, Afrikanova I, Wilson M, King CC, Maurer B, Yeo GW, Hayek A, Pasquinelli AE. PMID: 19807270.

View in: PubMed Mentions: 22 Fields:
Cel Cell Biology Hem Hematology
Translation:Humans Animals Cells
A novel approach for the derivation of putative primordial germ cells and sertoli cells from human embryonic stem cells. Stem Cells. 2009 Jan; 27(1):68-77. Bucay N, Yebra M, Cirulli V, Afrikanova I, Kaido T, Hayek A, Montgomery AM. PMID: 18845765.

View in: PubMed Mentions: 56 Fields:
Cel Cell Biology Emb Embryology
Translation:Humans Animals Cells
Generation of definitive endoderm from human embryonic stem cells cultured in feeder layer-free conditions. Regen Med. 2008 Mar; 3(2):175-80. King CC, Beattie GM, Lopez AD, Hayek A. PMID: 18307401.

View in: PubMed Mentions: 4 Fields:
Bio Biotechnology
Translation:Humans Animals Cells
Limited capacity of human adult islets expanded in vitro to redifferentiate into insulin-producing beta-cells. Diabetes. 2007 Mar; 56(3):703-8. Kayali AG, Flores LE, Lopez AD, Kutlu B, Baetge E, Kitamura R, Hao E, Beattie GM, Hayek A. PMID: 17327439.

View in: PubMed Mentions: 16 Fields:
End Endocrinology
Translation:Humans Animals Cells
Cell replacement in type 1 diabetes mellitus. J Pediatr Endocrinol Metab. 2005 Dec; 18 Suppl 1:1157-61. Hayek A. PMID: 16398444.

View in: PubMed Mentions: 1 Fields:
End Endocrinology Ped Pediatrics
Translation:Humans Animals Cells
Alphav-integrin utilization in human beta-cell adhesion, spreading, and motility. J Biol Chem. 2004 Apr 23; 279(17):17731-7. Kaido T, Perez B, Yebra M, Hill J, Cirulli V, Hayek A, Montgomery AM. PMID: 14766759.

View in: PubMed Mentions: 25 Fields:
Bio Biochemistry
Translation:Humans Cells
Maintenance of pluripotency in human embryonic stem cells is STAT3 independent. Stem Cells. 2004; 22(4):522-30. Humphrey RK, Beattie GM, Lopez AD, Bucay N, King CC, Firpo MT, Rose-John S, Hayek A. PMID: 15277698.

View in: PubMed Mentions: 64 Fields:
Cel Cell Biology Emb Embryology
Translation:Humans Animals Cells
In search of endocrine progenitor/stem cells in the human pancreas. Pediatr Diabetes. 2004; 5 Suppl 2:70-4. Hayek A. PMID: 15601376.

View in: PubMed Mentions: 1 Fields:
End Endocrinology
Translation:Humans Animals Cells
Characterization and isolation of promoter-defined nestin-positive cells from the human fetal pancreas. Diabetes. 2003 Oct; 52(10):2519-25. Humphrey RK, Bucay N, Beattie GM, Lopez A, Messam CA, Cirulli V, Hayek A. PMID: 14514635.

View in: PubMed Mentions: 18 Fields:
End Endocrinology
Translation:Humans Animals Cells
A novel approach to increase human islet cell mass while preserving beta-cell function. Diabetes. 2002 Dec; 51(12):3435-9. Beattie GM, Montgomery AM, Lopez AD, Hao E, Perez B, Just ML, Lakey JR, Hart ME, Hayek A. PMID: 12453897.

View in: PubMed Mentions: 53 Fields:
End Endocrinology
Translation:Humans Animals Cells
Exendin 4 up-regulates expression of PDX 1 and hastens differentiation and maturation of human fetal pancreatic cells. J Clin Endocrinol Metab. 2002 Oct; 87(10):4775-81. Movassat J, Beattie GM, Lopez AD, Hayek A. PMID: 12364473.

View in: PubMed Mentions: 30 Fields:
End Endocrinology Met Metabolism
Translation:Humans Animals Cells
Alternatives to unmodified human islets for transplantation. Curr Diab Rep. 2002 Aug; 2(4):371-6. Hayek A, Beattie GM. PMID: 12643198.

View in: PubMed Mentions: 2 Fields:
End Endocrinology
Translation:Humans Animals Cells
Regulation of pancreatic cell differentiation and morphogenesis. Pediatr Diabetes. 2002 Mar; 3(1):46-63. Humphrey RK, Smith MS, Tuch BE, Hayek A. PMID: 15016175.

View in: PubMed Mentions: Fields:
End Endocrinology
Experimental transplantation of human fetal and adult pancreatic islets. J Clin Endocrinol Metab. 1997 Aug; 82(8):2471-5. Hayek A, Beattie GM. PMID: 9253320.

View in: PubMed Mentions: 20 Fields:
End Endocrinology Met Metabolism
Translation:Humans Animals
Processing, storage and experimental transplantation of human fetal pancreatic cells. Ann Transplant. 1997; 2(3):46-54. Hayek A, Beattie GM. PMID: 9869864.

View in: PubMed Mentions: 6 Fields:
Tra Transplantation
Translation:Humans Animals