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Alberto Hayek

Title(s)Senate Emeritus, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    SMALL INSTRUMENTATION GRANT
    NIH/NIDDK S15DK046038Aug 1, 1992 - Jul 31, 1993
    Role: Principal Investigator
    SMALL INSTRUMENTATION GRANT
    NIH/NIDDK S15DK044705Aug 1, 1991 - Jul 31, 1992
    Role: Principal Investigator
    SMALL INSTRUMENTATION GRANT
    NIH/NIDDK S15DK043427Jul 15, 1990 - Jun 30, 1991
    Role: Principal Investigator
    ISLET TRANSPLANTATION IN EXPERIMENTAL DIABETES
    NIH/NIDDK R01DK039087Dec 1, 1988 - Nov 30, 1995
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chemical combinations potentiate human pluripotent stem cell-derived 3D pancreatic progenitor clusters toward functional β cells. Nat Commun. 2021 06 07; 12(1):3330. Liu H, Li R, Liao HK, Min Z, Wang C, Yu Y, Shi L, Dan J, Hayek A, Martinez Martinez L, Nuñez Delicado E, Izpisua Belmonte JC. PMID: 34099664; PMCID: PMC8184986.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Lessons Learned in War. Perm J. 2017; 21:16-176. Hayek A. PMID: 28633730; PMCID: PMC5478589.
      View in: PubMed   Mentions:    Fields:    
    3. Brief review: cell replacement therapies to treat type 1 diabetes mellitus. Clin Diabetes Endocrinol. 2016; 2:4. Hayek A, King CC. PMID: 28702240; PMCID: PMC5471705.
      View in: PubMed   Mentions: 3  
    4. sRNA-seq analysis of human embryonic stem cells and definitive endoderm reveals differentially expressed microRNAs and novel IsomiRs with distinct targets. Stem Cells. 2014 Sep; 32(9):2360-72. Hinton A, Hunter SE, Afrikanova I, Jones GA, Lopez AD, Fogel GB, Hayek A, King CC. PMID: 24805944.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    5. Isolation, culture, and imaging of human fetal pancreatic cell clusters. J Vis Exp. 2014 May 18; (87). Lopez AD, Kayali AG, Hayek A, King CC. PMID: 24895054; PMCID: PMC4193289.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    6. Is stage-specific embryonic antigen 4 a marker for human ductal stem/progenitor cells? Biores Open Access. 2012 Aug; 1(4):184-91. Afrikanova I, Kayali A, Lopez A, Hayek A. PMID: 23515456; PMCID: PMC3559232.
      View in: PubMed   Mentions: 3  
    7. Kartogenin: a game-changer in regenerative medicine. Regen Med. 2012 Jul; 7(4):475. Hayek A, Kerstetter-Fogle AE, Sachlos E, Bollenbach T. PMID: 22993885.
      View in: PubMed   Mentions: 2     Fields:    
    8. Pumping iron in the brain. Regen Med. 2012 Jul; 7(4):474. Hayek A, Kerstetter-Fogle AE, Sachlos E, Bollenbach T. PMID: 22993884.
      View in: PubMed   Mentions:    Fields:    
    9. Generation of functional hair follicles from follicle germs in a nude mouse model of organ replacement regenerative therapy. Regen Med. 2012 Jul; 7(4):475-6. Hayek A, Kerstetter-Fogle AE, Sachlos E, Bollenbach T. PMID: 22993886.
      View in: PubMed   Mentions:    Fields:    
    10. A new factory for insulin-producing cells: the gut? Regen Med. 2012 Jul; 7(4):473. Hayek A, Kerstetter-Fogle AE, Sachlos E, Bollenbach T. PMID: 22817622.
      View in: PubMed   Mentions:    Fields:    
    11. The SDF-1α/CXCR4 axis is required for proliferation and maturation of human fetal pancreatic endocrine progenitor cells. PLoS One. 2012; 7(6):e38721. Kayali AG, Lopez AD, Hao E, Hinton A, Hayek A, King CC. PMID: 22761699; PMCID: PMC3382144.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    12. Inhibitors of Src and focal adhesion kinase promote endocrine specification: impact on the derivation of β-cells from human pluripotent stem cells. J Biol Chem. 2011 Oct 14; 286(41):36042-36052. Afrikanova I, Yebra M, Simpkinson M, Xu Y, Hayek A, Montgomery A. PMID: 21852242; PMCID: PMC3195622.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    13. Impact of integrin-matrix interaction and signaling on insulin gene expression and the mesenchymal transition of human beta-cells. J Cell Physiol. 2010 Jul; 224(1):101-11. Kaido TJ, Yebra M, Kaneto H, Cirulli V, Hayek A, Montgomery AM. PMID: 20232313.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    14. A distinct microRNA signature for definitive endoderm derived from human embryonic stem cells. Stem Cells Dev. 2010 Jun; 19(6):797-807. Hinton A, Afrikanova I, Wilson M, King CC, Maurer B, Yeo GW, Hayek A, Pasquinelli AE. PMID: 19807270.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    15. Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proc Natl Acad Sci U S A. 2010 May 04; 107(18):8129-34. Xu Y, Zhu X, Hahm HS, Wei W, Hao E, Hayek A, Ding S. PMID: 20406903; PMCID: PMC2889586.
      View in: PubMed   Mentions: 133     Fields:    Translation:HumansAnimalsCells
    16. Generation of human-induced pluripotent stem cells in the absence of exogenous Sox2. Stem Cells. 2009 Dec; 27(12):2992-3000. Li W, Zhou H, Abujarour R, Zhu S, Young Joo J, Lin T, Hao E, Schöler HR, Hayek A, Ding S. PMID: 19839055; PMCID: PMC3780784.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansAnimalsCells
    17. A chemical platform for improved induction of human iPSCs. Nat Methods. 2009 Nov; 6(11):805-8. Lin T, Ambasudhan R, Yuan X, Li W, Hilcove S, Abujarour R, Lin X, Hahm HS, Hao E, Hayek A, Ding S. PMID: 19838168; PMCID: PMC3724527.
      View in: PubMed   Mentions: 206     Fields:    Translation:HumansCells
    18. A novel approach for the derivation of putative primordial germ cells and sertoli cells from human embryonic stem cells. Stem Cells. 2009 Jan; 27(1):68-77. Bucay N, Yebra M, Cirulli V, Afrikanova I, Kaido T, Hayek A, Montgomery AM. PMID: 18845765.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    19. Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors. Cell Stem Cell. 2009 Jan 09; 4(1):16-9. Li W, Wei W, Zhu S, Zhu J, Shi Y, Lin T, Hao E, Hayek A, Deng H, Ding S. PMID: 19097958.
      View in: PubMed   Mentions: 192     Fields:    Translation:HumansAnimalsCells
    20. Generation of definitive endoderm from human embryonic stem cells cultured in feeder layer-free conditions. Regen Med. 2008 Mar; 3(2):175-80. King CC, Beattie GM, Lopez AD, Hayek A. PMID: 18307401.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    21. Stopping diabetes in its tracks: autologous non-myeloablative stem cell transplantation. Regen Med. 2007 Sep; 2(5):845-51. Fousteri G, Hayek A, von Herrath M. PMID: 17907936.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    22. Limited capacity of human adult islets expanded in vitro to redifferentiate into insulin-producing beta-cells. Diabetes. 2007 Mar; 56(3):703-8. Kayali AG, Flores LE, Lopez AD, Kutlu B, Baetge E, Kitamura R, Hao E, Beattie GM, Hayek A. PMID: 17327439.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    23. Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions. Proc Natl Acad Sci U S A. 2006 May 02; 103(18):6907-12. Yao S, Chen S, Clark J, Hao E, Beattie GM, Hayek A, Ding S. PMID: 16632596; PMCID: PMC1458992.
      View in: PubMed   Mentions: 145     Fields:    Translation:HumansAnimalsCells
    24. Cell replacement in type 1 diabetes mellitus. J Pediatr Endocrinol Metab. 2005 Dec; 18 Suppl 1:1157-61. Hayek A. PMID: 16398444.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    25. Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers. Stem Cells. 2005 Apr; 23(4):489-95. Beattie GM, Lopez AD, Bucay N, Hinton A, Firpo MT, King CC, Hayek A. PMID: 15790770.
      View in: PubMed   Mentions: 171     Fields:    Translation:HumansAnimalsCells
    26. Alphav-integrin utilization in human beta-cell adhesion, spreading, and motility. J Biol Chem. 2004 Apr 23; 279(17):17731-7. Kaido T, Perez B, Yebra M, Hill J, Cirulli V, Hayek A, Montgomery AM. PMID: 14766759.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    27. Maintenance of pluripotency in human embryonic stem cells is STAT3 independent. Stem Cells. 2004; 22(4):522-30. Humphrey RK, Beattie GM, Lopez AD, Bucay N, King CC, Firpo MT, Rose-John S, Hayek A. PMID: 15277698.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimalsCells
    28. In search of endocrine progenitor/stem cells in the human pancreas. Pediatr Diabetes. 2004; 5 Suppl 2:70-4. Hayek A. PMID: 15601376.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    29. Characterization and isolation of promoter-defined nestin-positive cells from the human fetal pancreas. Diabetes. 2003 Oct; 52(10):2519-25. Humphrey RK, Bucay N, Beattie GM, Lopez A, Messam CA, Cirulli V, Hayek A. PMID: 14514635.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    30. A novel approach to increase human islet cell mass while preserving beta-cell function. Diabetes. 2002 Dec; 51(12):3435-9. Beattie GM, Montgomery AM, Lopez AD, Hao E, Perez B, Just ML, Lakey JR, Hart ME, Hayek A. PMID: 12453897.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    31. Exendin 4 up-regulates expression of PDX 1 and hastens differentiation and maturation of human fetal pancreatic cells. J Clin Endocrinol Metab. 2002 Oct; 87(10):4775-81. Movassat J, Beattie GM, Lopez AD, Hayek A. PMID: 12364473.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    32. Alternatives to unmodified human islets for transplantation. Curr Diab Rep. 2002 Aug; 2(4):371-6. Hayek A, Beattie GM. PMID: 12643198.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    33. Regulation of pancreatic cell differentiation and morphogenesis. Pediatr Diabetes. 2002 Mar; 3(1):46-63. Humphrey RK, Smith MS, Tuch BE, Hayek A. PMID: 15016175.
      View in: PubMed   Mentions:    Fields:    
    34. Experimental transplantation of human fetal and adult pancreatic islets. J Clin Endocrinol Metab. 1997 Aug; 82(8):2471-5. Hayek A, Beattie GM. PMID: 9253320.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    35. Processing, storage and experimental transplantation of human fetal pancreatic cells. Ann Transplant. 1997; 2(3):46-54. Hayek A, Beattie GM. PMID: 9869864.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
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