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    Steven Wasserman

    SchoolUniversity of California, San Diego
    DepartmentCell and Developmental Biology
    Address9500 Gilman Drive #0349
    CA La Jolla 92093
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      Collapse Research 
      Collapse Research Activities and Funding
      NIH/NIGMS R01GM060990Mar 1, 2000 - Feb 29, 2004
      Role: Principal Investigator
      Structure and Function of Drosophila NF-kappaB Signaling Pathways
      NIH/NIGMS R01GM050545Aug 1, 1994 - Jul 31, 2019
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Ko KI, Root CM, Lindsay SA, Zaninovich OA, Shepherd AK, Wasserman S, Kim SM, Wang JW. Starvation promotes concerted modulation of appetitive olfactory behavior via parallel neuromodulatory circuits. Elife. 2015 Jul 24; 4. PMID: 26208339; PMCID: PMC4531282.
      2. Zhou B, Lindsay SA, Wasserman S. Alternative NF-?B Isoforms in the Drosophila Neuromuscular Junction and Brain. PLoS One. 2015; 10(7):e0132793. PMID: 26167685; PMCID: PMC4500392.
      3. Higgins R, Gendron JM, Rising L, Mak R, Webb K, Kaiser SE, Zuzow N, Riviere P, Yang B, Fenech E, Tang X, Lindsay SA, Christianson JC, Hampton RY, Wasserman S, Bennett EJ. The Unfolded Protein Response Triggers Site-Specific Regulatory Ubiquitylation of 40S Ribosomal Proteins. Mol Cell. 2015 Jul 02; 59(1):35-49. PMID: 26051182; PMCID: PMC4491043.
      4. Clemmons AW, Lindsay SA, Wasserman S. An effector Peptide family required for Drosophila toll-mediated immunity. PLoS Pathog. 2015 Apr; 11(4):e1004876. PMID: 25915418; PMCID: PMC4411088.
      5. Daigneault J, Klemetsaune L, Wasserman S. The IRAK homolog Pelle is the functional counterpart of I?B kinase in the Drosophila Toll pathway. PLoS One. 2013; 8(9):e75150. PMID: 24086459; PMCID: PMC3781037.
      6. Clemmons AW, Wasserman S. Combinatorial effects of transposable elements on gene expression and phenotypic robustness in Drosophila melanogaster development. G3 (Bethesda). 2013 Sep 04; 3(9):1531-8. PMID: 23833214; PMCID: PMC3755913.
      7. Lindsay SA, Wasserman S. Conventional and non-conventional Drosophila Toll signaling. Dev Comp Immunol. 2014 Jan; 42(1):16-24. PMID: 23632253; PMCID: PMC3787077.
      8. Lattao R, Bonaccorsi S, Guan X, Wasserman S, Gatti M. Tubby-tagged balancers for the Drosophila X and second chromosomes. Fly (Austin). 2011 Oct-Dec; 5(4):369-70. PMID: 21785267; PMCID: PMC3266079.
      9. Towb P, Sun H, Wasserman S. Tube Is an IRAK-4 homolog in a Toll pathway adapted for development and immunity. J Innate Immun. 2009; 1(4):309-21. PMID: 19498957.
        View in: PubMed
      10. Busse MS, Arnold CP, Towb P, Katrivesis J, Wasserman S. A kappaB sequence code for pathway-specific innate immune responses. EMBO J. 2007 Aug 22; 26(16):3826-35. PMID: 17660749; PMCID: PMC1952218.
      11. Franklin-Dumont TM, Chatterjee C, Wasserman S, Dinardo S. A novel eIF4G homolog, Off-schedule, couples translational control to meiosis and differentiation in Drosophila spermatocytes. Development. 2007 Aug; 134(15):2851-61. PMID: 17611222.
        View in: PubMed
      12. Guan X, Middlebrooks BW, Alexander S, Wasserman S. Mutation of TweedleD, a member of an unconventional cuticle protein family, alters body shape in Drosophila. Proc Natl Acad Sci U S A. 2006 Nov 07; 103(45):16794-9. PMID: 17075064; PMCID: PMC1636534.
      13. Wasserman S. Nature's fortress against infection. Nat Immunol. 2004 May; 5(5):474-5. PMID: 15116113.
        View in: PubMed
      14. Park JM, Brady H, Ruocco MG, Sun H, Williams D, Lee SJ, Kato T, Richards N, Chan K, Mercurio F, Karin M, Wasserman S. Targeting of TAK1 by the NF-kappa B protein Relish regulates the JNK-mediated immune response in Drosophila. Genes Dev. 2004 Mar 01; 18(5):584-94. PMID: 15037551; PMCID: PMC374239.
      15. Sun H, Towb P, Chiem DN, Foster BA, Wasserman S. Regulated assembly of the Toll signaling complex drives Drosophila dorsoventral patterning. EMBO J. 2004 Jan 14; 23(1):100-10. PMID: 14685264; PMCID: PMC1271671.
      16. Sun H, Bristow BN, Qu G, Wasserman S. A heterotrimeric death domain complex in Toll signaling. Proc Natl Acad Sci U S A. 2002 Oct 01; 99(20):12871-6. PMID: 12351681; PMCID: PMC130552.
      17. Wasserman S, DiNardo S. Development. Staying a boy forever. Science. 2001 Dec 21; 294(5551):2495-7. PMID: 11752564.
        View in: PubMed
      18. Towb P, Bergmann A, Wasserman S. The protein kinase Pelle mediates feedback regulation in the Drosophila Toll signaling pathway. Development. 2001 Dec; 128(23):4729-36. PMID: 11731453.
        View in: PubMed
      19. Afshar K, Gönczy P, DiNardo S, Wasserman S. fumble encodes a pantothenate kinase homolog required for proper mitosis and meiosis in Drosophila melanogaster. Genetics. 2001 Mar; 157(3):1267-76. PMID: 11238410; PMCID: PMC1461544.
      20. Wasserman S. Toll signaling: the enigma variations. Curr Opin Genet Dev. 2000 Oct; 10(5):497-502. PMID: 10980426.
        View in: PubMed
      21. Wasserman S. Multi-layered regulation of courtship behaviour. Nat Cell Biol. 2000 Aug; 2(8):E145-6. PMID: 10934486.
        View in: PubMed
      22. Afshar K, Stuart B, Wasserman S. Functional analysis of the Drosophila diaphanous FH protein in early embryonic development. Development. 2000 May; 127(9):1887-97. PMID: 10751177.
        View in: PubMed
      23. Zapata JM, Matsuzawa S, Godzik A, Leo E, Wasserman S, Reed JC. The Drosophila tumor necrosis factor receptor-associated factor-1 (DTRAF1) interacts with Pelle and regulates NFkappaB activity. J Biol Chem. 2000 Apr 21; 275(16):12102-7. PMID: 10766844.
        View in: PubMed
      24. Xiao T, Towb P, Wasserman S, Sprang SR. Three-dimensional structure of a complex between the death domains of Pelle and Tube. Cell. 1999 Nov 24; 99(5):545-55. PMID: 10589682; PMCID: PMC4372121.
      25. Thomas JA, Allen JL, Tsen M, Dubnicoff T, Danao J, Liao XC, Cao Z, Wasserman S. Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase. J Immunol. 1999 Jul 15; 163(2):978-84. PMID: 10395695.
        View in: PubMed
      26. Maines JZ, Wasserman S. Post-transcriptional regulation of the meiotic Cdc25 protein Twine by the Dazl orthologue Boule. Nat Cell Biol. 1999 Jul; 1(3):171-4. PMID: 10559904.
        View in: PubMed
      27. Cheng MH, Maines JZ, Wasserman S. Biphasic subcellular localization of the DAZL-related protein boule in Drosophila spermatogenesis. Dev Biol. 1998 Dec 15; 204(2):567-76. PMID: 9882490.
        View in: PubMed
      28. Towb P, Galindo RL, Wasserman S. Recruitment of Tube and Pelle to signaling sites at the surface of the Drosophila embryo. Development. 1998 Jul; 125(13):2443-50. PMID: 9609827.
        View in: PubMed
      29. Houston DW, Zhang J, Maines JZ, Wasserman S, King ML. A Xenopus DAZ-like gene encodes an RNA component of germ plasm and is a functional homologue of Drosophila boule. Development. 1998 Jan; 125(2):171-80. PMID: 9486791.
        View in: PubMed
      30. Liu ZP, Galindo RL, Wasserman S. A role for CKII phosphorylation of the cactus PEST domain in dorsoventral patterning of the Drosophila embryo. Genes Dev. 1997 Dec 15; 11(24):3413-22. PMID: 9407033; PMCID: PMC316825.
      31. Edwards DN, Towb P, Wasserman S. An activity-dependent network of interactions links the Rel protein Dorsal with its cytoplasmic regulators. Development. 1997 Oct; 124(19):3855-64. PMID: 9367441.
        View in: PubMed
      32. Cenci G, Rawson RB, Belloni G, Castrillon DH, Tudor M, Petrucci R, Goldberg ML, Wasserman S, Gatti M. UbcD1, a Drosophila ubiquitin-conjugating enzyme required for proper telomere behavior. Genes Dev. 1997 Apr 01; 11(7):863-75. PMID: 9106658.
        View in: PubMed
      33. Ryner LC, Goodwin SF, Castrillon DH, Anand A, Villella A, Baker BS, Hall JC, Taylor BJ, Wasserman S. Control of male sexual behavior and sexual orientation in Drosophila by the fruitless gene. Cell. 1996 Dec 13; 87(6):1079-89. PMID: 8978612.
        View in: PubMed
      34. Reach M, Galindo RL, Towb P, Allen JL, Karin M, Wasserman S. A gradient of cactus protein degradation establishes dorsoventral polarity in the Drosophila embryo. Dev Biol. 1996 Nov 25; 180(1):353-64. PMID: 8948598.
        View in: PubMed
      35. Eberhart CG, Maines JZ, Wasserman S. Meiotic cell cycle requirement for a fly homologue of human Deleted in Azoospermia. Nature. 1996 Jun 27; 381(6585):783-5. PMID: 8657280.
        View in: PubMed
      36. Eberhart CG, Wasserman S. The pelota locus encodes a protein required for meiotic cell division: an analysis of G2/M arrest in Drosophila spermatogenesis. Development. 1995 Oct; 121(10):3477-86. PMID: 7588080.
        View in: PubMed
      37. Galindo RL, Edwards DN, Gillespie SK, Wasserman S. Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos. Development. 1995 Jul; 121(7):2209-18. PMID: 7635064.
        View in: PubMed
      38. Castrillon DH, Wasserman S. Diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene. Development. 1994 Dec; 120(12):3367-77. PMID: 7821209.
        View in: PubMed
      39. Gillespie SK, Wasserman S. Dorsal, a Drosophila Rel-like protein, is phosphorylated upon activation of the transmembrane protein Toll. Mol Cell Biol. 1994 Jun; 14(6):3559-68. PMID: 8196601; PMCID: PMC358723.
      40. Castrillon DH, Gönczy P, Alexander S, Rawson R, Eberhart CG, Viswanathan S, DiNardo S, Wasserman S. Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis. Genetics. 1993 Oct; 135(2):489-505. PMID: 8244010; PMCID: PMC1205651.
      41. Letsou A, Alexander S, Wasserman S. Domain mapping of tube, a protein essential for dorsoventral patterning of the Drosophila embryo. EMBO J. 1993 Sep; 12(9):3449-58. PMID: 8253071; PMCID: PMC413621.
      42. Wasserman S. A conserved signal transduction pathway regulating the activity of the rel-like proteins dorsal and NF-kappa B. Mol Biol Cell. 1993 Aug; 4(8):767-71. PMID: 8241564; PMCID: PMC300990.
      43. Shelton CA, Wasserman S. pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo. Cell. 1993 Feb 26; 72(4):515-25. PMID: 8440018.
        View in: PubMed
      44. Letsou A, Alexander S, Orth K, Wasserman S. Genetic and molecular characterization of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity. Proc Natl Acad Sci U S A. 1991 Feb 01; 88(3):810-4. PMID: 1899484; PMCID: PMC50903.
      45. Johnston PA, Perin MS, Reynolds GA, Wasserman S, Südhof TC. Two novel annexins from Drosophila melanogaster. Cloning, characterization, and differential expression in development. J Biol Chem. 1990 Jul 05; 265(19):11382-8. PMID: 2141610.
        View in: PubMed
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