H Broome

Title(s)	Clinical Professor, Pathology
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia. Nat Cancer. 2020 04; 1(4):410-422. Bajaj J, Hamilton M, Shima Y, Chambers K, Spinler K, Van Nostrand EL, Yee BA, Blue SM, Chen M, Rizzeri D, Chuah C, Oehler VG, Broome HE, Sasik R, Scott-Browne J, Rao A, Yeo GW, Reya T. PMID: 34109316; PMCID: PMC8186448.

View in: PubMed Mentions: 23 Fields:
Neo Neoplasms
Translation:Animals Cells
Comparison of Different Small Clinical Hematology Laboratory Configurations With Focus on Remote Smear Imaging. Arch Pathol Lab Med. 2019 10; 143(10):1234-1245. Stephens L, Bevins NJ, Bengtsson HI, Broome HE. PMID: 30969157.

View in: PubMed Mentions: 3 Fields:
Pat Pathology
Translation:Humans
JAK2 double minutes with resultant simultaneous amplification of JAK2 and CD274 in a therapy-related myelodysplastic syndrome evolving into an acute myeloid leukaemia. Br J Haematol. 2019 05; 185(3):566-570. Wang HY, Dell'Aquila ML, Dvanajscak Z, Bejar R, Broome HE, Hsi E, Murray SS, Thorson JA. PMID: 30132795.

View in: PubMed Mentions: 3 Fields:
Hem Hematology
Translation:Humans
Impact of Integrating Rumke Statistics to Assist with Choosing Between Automated Hematology Analyzer Differentials vs Manual Differentials. J Appl Lab Med. 2017 Jan 01; 1(4):357-364. Stephens L, Hintz-Prunty W, Bengtsson HI, Proudfoot JA, Patel SP, Broome HE. PMID: 33636799.

View in: PubMed Mentions: 2 Fields:
Cli Clinical Laboratory Techniques
Successful treatment of both double minute of C-MYC and BCL-2 rearrangement containing large B-cell lymphoma with subsequent unfortunate development of therapy-related acute myeloid leukemia with t(3;3)(q26.2;q21). Pathol Res Pract. 2015 Nov; 211(11):883-91. Nguyen JC, Kubik MJ, Broome HE, Curtin PT, Dell'Aquila ML, Wang HY. PMID: 26300063.

View in: PubMed Mentions: 1 Fields:
Pat Pathology
Translation:Humans Cells
Myeloid neoplasm with t(3;8)(q26;q24): report of six cases and review of the literature. Leuk Lymphoma. 2014 Nov; 55(11):2532-7. Xu X, Su M, Levy NB, Mohtashamian A, Monaghan S, Kaur P, Zaremba C, Garcia R, Broome HE, Dell'Aquila ML, Wang HY. PMID: 24397594.

View in: PubMed Mentions: 2 Fields:
Hem Hematology Neo Neoplasms
Translation:Humans Cells
Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia. Nat Genet. 2014 Mar; 46(3):245-52. Zimdahl B, Ito T, Blevins A, Bajaj J, Konuma T, Weeks J, Koechlein CS, Kwon HY, Arami O, Rizzieri D, Broome HE, Chuah C, Oehler VG, Sasik R, Hardiman G, Reya T. PMID: 24487275; PMCID: PMC4267534.

View in: PubMed Mentions: 52 Fields:
Gen Genetics
Translation:Humans Animals Cells
A rare and unique case of aggressive IgE-λ plasma cell myeloma in a 28-year-old woman presented initially as an orbital mass. Hum Pathol. 2012 Dec; 43(12):2376-84. Li K, Ku G, Yan M, Broome HE, Kelner M, Wang HY. PMID: 23084304.

View in: PubMed Mentions: 3 Fields:
Pat Pathology
Translation:Humans Cells
A case of concomitant T-cell large granular lymphocytic leukemia and plasma cell myeloma. Clin Adv Hematol Oncol. 2011 Dec; 9(12):958-9. Broome HE, Wang HY. PMID: 22252669.

View in: PubMed Mentions: 2 Fields:
Hem Hematology Neo Neoplasms
Translation:Humans
ROR1 is expressed on hematogones (non-neoplastic human B-lymphocyte precursors) and a minority of precursor-B acute lymphoblastic leukemia. Leuk Res. 2011 Oct; 35(10):1390-4. Broome HE, Rassenti LZ, Wang HY, Meyer LM, Kipps TJ. PMID: 21813176; PMCID: PMC3163753.

View in: PubMed Mentions: 47 Fields:
Neo Neoplasms
Translation:Humans Cells
t(4;22)(q12;q11.2) involving presumptive platelet-derived growth factor receptor A and break cluster region in a patient with mixed phenotype acute leukemia. Hum Pathol. 2011 Dec; 42(12):2029-36. Wang HY, Thorson JA, Broome HE, Rashidi HH, Curtin PT, Dell'Aquila ML. PMID: 21676437.

View in: PubMed Mentions: 2 Fields:
Pat Pathology
Translation:Humans Cells
Monoclonal antibodies in the treatment of hematologic malignancy. Best Pract Res Clin Haematol. 2010 Sep; 23(3):403-16. Ball ED, Broome HE. PMID: 21112039.

View in: PubMed Mentions: Fields:
Hem Hematology
Translation:Humans Animals
Systemic mastocytosis in association with chronic lymphocytic leukemia and plasma cell myeloma. Int J Clin Exp Pathol. 2010 Apr 23; 3(4):448-57. Du S, Rashidi HH, Le DT, Kipps TJ, Broome HE, Wang HY. PMID: 20490336; PMCID: PMC2872752.

View in: PubMed Mentions: 3 Fields:
Pat Pathology
Translation:Humans
FLAG chemotherapy followed by allogeneic stem cell transplant using nonmyeloablative conditioning induces regression of myelofibrosis with myeloid metaplasia. Bone Marrow Transplant. 2003 Sep; 32(6):581-5. Tanner ML, Hoh CK, Bashey A, Holman P, Sun C, Broome HE, Lane T, Ball ED, Carrier E. PMID: 12953130.

View in: PubMed Mentions: 3 Fields:
Tra Transplantation
Translation:Humans
Inhibition of Bcl-xL expression sensitizes T-cell acute lymphoblastic leukemia cells to chemotherapeutic drugs. Leuk Res. 2002 Mar; 26(3):311-6. Broome HE, Yu AL, Diccianni M, Camitta BM, Monia BP, Dean NM. PMID: 11792421.

View in: PubMed Mentions: 8 Fields:
Neo Neoplasms
Translation:Humans Cells
Sensitivity of S49.1 cells to anti-CD95 (Fas/Apo-1)-induced apoptosis: effects of CD95, Bcl-2 or Bcl-x transduction. Cell Death Differ. 1998 Mar; 5(3):200-5. Broome HE, Dargan CM, Brunner T, Green DR. PMID: 10200465.

View in: PubMed Mentions: 2 Fields:
Cel Cell Biology
Translation:Animals Cells
TCR triggering of anergic CD4 T cells in murine AIDS induces apoptosis rather than cytokine synthesis and proliferation. J Immunol. 1996 Jul 15; 157(2):625-35. Muralidhar G, Koch S, Broome HE, Swain SL. PMID: 8752910.

View in: PubMed Mentions: 2 Fields:
All Allergy and Immunology
Translation:Animals Cells
Expression of Bcl-2, Bcl-x, and Bax after T cell activation and IL-2 withdrawal. J Immunol. 1995 Sep 01; 155(5):2311-7. Broome HE, Dargan CM, Krajewski S, Reed JC. PMID: 7650367.

View in: PubMed Mentions: 31 Fields:
All Allergy and Immunology
Translation:Animals Cells
Control of CD4 effector fate: transforming growth factor beta 1 and interleukin 2 synergize to prevent apoptosis and promote effector expansion. J Exp Med. 1995 Sep 01; 182(3):699-709. Zhang X, Giangreco L, Broome HE, Dargan CM, Swain SL. PMID: 7650478; PMCID: PMC2192155.

View in: PubMed Mentions: 38 Fields:
All Allergy and Immunology Med Medicine (General)
Translation:Humans Animals Cells
Apoptosis and Bcl-2 expression in cultured murine splenic T cells. Immunology. 1995 Mar; 84(3):375-82. Broome HE, Dargan CM, Bessent EF, Krajewski S, Reed JC. PMID: 7751019; PMCID: PMC1415138.

View in: PubMed Mentions: 6 Fields:
All Allergy and Immunology
Translation:Animals Cells
Copper deficiency-induced anemia and neutropenia secondary to intestinal malabsorption. Am J Hematol. 1995 Jan; 48(1):45-7. Hayton BA, Broome HE, Lilenbaum RC. PMID: 7832191.

View in: PubMed Mentions: 2 Fields:
Hem Hematology
Translation:Humans