Structural and immunogenetic signatures guide CD4-mimetic HIV vaccine development. Cell Rep. 2026 Apr 15; 45(4):117180.
Bader DLV, Flynn CT, Kalyuzhniy O, Ozorowski G, Corcoran MM, Burns A, Altman P, Rouzeau R, Sincomb T, Liguori A, Fernández-Quintero ML, Loeffler JR, Torres JL, Turner HL, Georgeson E, Zhou A, Voic H, Goo S, Shahin L, Burton I, Wu M, Stanfield RL, Eskandarzadeh S, Lu D, Alavi N, Phelps N, Tingle R, McKenney K, Youhanna J, Amirzehni S, Schiffner T, Steichen JM, Burton DR, Wilson IA, Karlsson Hedestam GB, Landais E, Lee JH, Sok D, Cottrell CA, Ward AB, Schief WR. PMID: 41996239.
View in:
PubMed Mentions: Fields:
Vaccination with mRNA-encoded nanoparticles drives early maturation of HIV bnAb precursors in humans. Science. 2025 Jul 31; 389(6759):eadr8382.
Willis JR, Prabhakaran M, Muthui M, Naidoo A, Sincomb T, Wu W, Cottrell CA, Landais E, deCamp AC, Keshavarzi NR, Kalyuzhniy O, Lee JH, Murungi LM, Ogonda WA, Yates NL, Corcoran MM, Phulera S, Musando J, Tsai A, Lemire G, Sein Y, Muteti M, Alamuri P, Bohl JA, Holman D, Himansu S, Leav B, Reuter C, Lin LA, Ding B, He C, Straus WL, MacPhee KJ, Regadas I, Nyabundi DV, Chirchir R, Anzala O, Kimotho JN, Kibet C, Greene K, Gao H, Beatman E, Benson K, Laddy D, Brown DM, Bronson R, Jean-Baptiste J, Gajjala S, Rikhtegaran-Tehrani Z, Benner A, Ramaswami M, Lu D, Alavi N, Amirzehni S, Kubitz M, Tingle R, Georgeson E, Phelps N, Adachi Y, Liguori A, Flynn C, McKenney K, Zhou X, Owuor DC, Owuor SA, Kim SY, Duff M, Kim JY, Gibson G, Baboo S, Diedrich J, Schiffner T, Shields M, Matsoso M, Santos J, Syvertsen K, Kennedy A, Schroeter M, Vekemans J, Yates JR, Paulson JC, Hyrien O, McDermott AB, Maenetje P, Nyombayire J, Karita E, Ingabire R, Edward V, Muturi-Kioi V, Maenza J, Shapiro AE, McElrath MJ, Edupuganti S, Taylor BS, Diemert D, Ozorowski G, Koup RA, Montefiori D, Ward AB, Karlsson Hedestam GB, Tomaras G, Hunt DJ, Muema D, Sok D, Laufer DS, Andrews SF, Nduati EW, Schief WR. PMID: 40373112.