Robin Steinhorn

Title(s)Clinical Professor, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    Washington University, St. LouisMD05/1980Medicine
    University of Minnesota, Minneapolis06/1986Pediatrics
    University of Minnesota, Minneapolis06/1988Neonatal Perinatal Medicine
    Collapse Awards and Honors
    American Pediatric Society2019  - 2020President
    American Board of Pediatrics2017  - 2022Board of Directors
    Journal of Pediatrics2015  - ---Associate Editor

    Collapse Research 
    Collapse Research Activities and Funding
    Phase II Trial of Sildenafil in Newborns with Persistent Pulmonary Hyptertension
    NIH U01HL102235Sep 17, 2010 - Mar 31, 2013
    Role: Co-Principal Investigator
    REDOX REGULATION IN THE PERINATAL PULMONARY VASCULATURE
    NIH R01HL054705Aug 1, 1995 - Jun 30, 2015
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Optimizing respiratory management in preterm infants: a review of adjuvant pharmacotherapies. J Perinatol. 2021 Jul 09. Koo JK, Steinhorn R, C Katheria A. PMID: 34244615.
      View in: PubMed   Mentions:    Fields:    
    2. Efficacy and Safety of IV Sildenafil in the Treatment of Newborn Infants with, or at Risk of, Persistent Pulmonary Hypertension of the Newborn (PPHN): A Multicenter, Randomized, Placebo-Controlled Trial. J Pediatr. 2021 May 27. Pierce CM, Zhang MH, Jonsson B, Iorga D, Cheruvu N, Balagtas CC, Steinhorn RH. PMID: 34052232.
      View in: PubMed   Mentions:    Fields:    
    3. Development of a severity scale to assess chronic lung disease after extremely preterm birth. Pediatr Pulmonol. 2021 Jun; 56(6):1583-1592. O'Brodovich HM, Steinhorn R, Ward RM, Hallman M, Schwartz EJ, Vanya M, Janssen EM, Mangili A, Han L, Sarda SP. PMID: 33729710.
      View in: PubMed   Mentions: 1     Fields:    
    4. Valuing and achieving diversity in academic medicine : The APS and SPR Virtual Chat Series. Pediatr Res. 2020 Nov 19. Moxey-Mims M, Steinhorn R, Fuentes-Afflick E. PMID: 33214674.
      View in: PubMed   Mentions:    Fields:    
    5. Malnutrition, poor post-natal growth, intestinal dysbiosis and the developing lung. J Perinatol. 2021 Aug; 41(8):1797-1810. Underwood MA, Lakshminrusimha S, Steinhorn RH, Wedgwood S. PMID: 33057133.
      View in: PubMed   Mentions:    Fields:    
    6. Optimal Oxygen Targets in Term Lambs with Meconium Aspiration Syndrome and Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2020 10; 63(4):510-518. Rawat M, Chandrasekharan P, Gugino SF, Koenigsknecht C, Nielsen L, Wedgwood S, Mathew B, Nair J, Steinhorn R, Lakshminrusimha S. PMID: 32609558.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    7. Racism and social injustice as determinants of child health: the American Pediatric Society Issue of the Year. Pediatr Res. 2020 11; 88(5):691-693. Abman SH, Bogue CW, Baker S, Carlo W, Daniels SR, Debaun MR, Fike C, Gordon CM, Leonard MB, Steinhorn RH, Walker-Harding LR, American Pediatric Society (APS) . PMID: 32987397.
      View in: PubMed   Mentions:    Fields:    
    8. The american pediatric society and society for pediatric research joint statement against racism and social injustice. Pediatr Res. 2020 Sep 03. Abman SH, Armstrong S, Baker S, Bogue CW, Carlo W, Chalak L, Daniels SR, Davis S, Debaun MR, Fike C, Frazer L, Gibson K, Gill M, Glass H, Gordon CM, Goyal M, Hirschhorn J, Holtz L, Hunstad DA, Leonard MB, Maitre N, Markham L, McAllister-Lucas L, Orange J, Shah P, Simon T, Steinhorn RH, Tarini B, Walker-Harding LR. PMID: 32882704.
      View in: PubMed   Mentions:    Fields:    
    9. Late Rescue Collaborative: Reducing Non-ICU Arrests. Pediatr Crit Care Med. 2020 06; 21(6):513-519. Dean NP, Ghebremariam E, Szeles R, Levin A, Colyer J, Steinhorn RH. PMID: 31851129.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Severe Coronavirus Disease-2019 in Children and Young Adults in the Washington, DC, Metropolitan Region. J Pediatr. 2020 Aug; 223:199-203.e1. DeBiasi RL, Song X, Delaney M, Bell M, Smith K, Pershad J, Ansusinha E, Hahn A, Hamdy R, Harik N, Hanisch B, Jantausch B, Koay A, Steinhorn R, Newman K, Wessel D. PMID: 32405091.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCellsPHPublic Health
    11. Intestinal Dysbiosis and the Developing Lung: The Role of Toll-Like Receptor 4 in the Gut-Lung Axis. Front Immunol. 2020; 11:357. Wedgwood S, Gerard K, Halloran K, Hanhauser A, Monacelli S, Warford C, Thai PN, Chiamvimonvat N, Lakshminrusimha S, Steinhorn RH, Underwood MA. PMID: 32194566.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    12. The Impact of Telemedicine on Transfer Rates of Newborns at Rural Community Hospitals. Acad Pediatr. 2020 07; 20(5):636-641. Haynes SC, Dharmar M, Hill BC, Hoffman KR, Donohue LT, Kuhn-Riordon KM, Rottkamp CA, Vali P, Tancredi DJ, Romano PS, Steinhorn R, Marcin JP. PMID: 32081766.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Oxygen and pulmonary vasodilation: The role of oxidative and nitrosative stress. Semin Fetal Neonatal Med. 2020 04; 25(2):101083. Steinhorn RH, Lakshminrusimha S. PMID: 31983672.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    14. How to introduce MSC-based therapy for the developing lung safely into clinical care? Pediatr Res. 2020 09; 88(3):365-368. Rüdiger M, Kirpalani H, Steinhorn R, Davis JM, Thebaud B. PMID: 31931507.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    15. Breastfeeding, Baby-Friendly, and Safety: Getting the Balance Right. J Pediatr. 2020 03; 218:7-8. Steinhorn RH. PMID: 31810631.
      View in: PubMed   Mentions: 2     Fields:    
    16. To improve outcomes of prematurity, we must keep mothers healthy. J Pediatr. 2019 Dec; 215:1-3. Steinhorn RH. PMID: 31761133.
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    17. Bronchopulmonary dysplasia. Nat Rev Dis Primers. 2019 11 14; 5(1):78. Thébaud B, Goss KN, Laughon M, Whitsett JA, Abman SH, Steinhorn RH, Aschner JL, Davis PG, McGrath-Morrow SA, Soll RF, Jobe AH. PMID: 31727986.
      View in: PubMed   Mentions: 78     Fields:    Translation:Humans
    18. Risk Assessment and Monitoring of Chronic Pulmonary Hypertension in Premature Infants. J Pediatr. 2020 02; 217:199-209.e4. Levy PT, Jain A, Nawaytou H, Teitel D, Keller R, Fineman J, Steinhorn R, Abman SH, McNamara PJ, Pediatric Pulmonary Hypertension Network (PPHNet) . PMID: 31735418.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    19. Could genetic variations explain variability in neonatal opiate withdrawal syndrome? J Pediatr. 2019 Nov; 214:1-3. Steinhorn RH. PMID: 31655688.
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    20. The developing gut-lung axis: postnatal growth restriction, intestinal dysbiosis, and pulmonary hypertension in a rodent model. Pediatr Res. 2020 02; 87(3):472-479. Wedgwood S, Warford C, Agvatisiri SR, Thai PN, Chiamvimonvat N, Kalanetra KM, Lakshminrusimha S, Steinhorn RH, Mills DA, Underwood MA. PMID: 31537010.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    21. Adding to the controversy of postnatal steroids for preterm infants. J Pediatr. 2019 Aug; 211:1-3. Steinhorn RH. PMID: 31349911.
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    22. Who goes home on oxygen after a NICU stay? J Pediatr. 2019 Jul; 210:1-2. Steinhorn RH. PMID: 31234976.
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    23. Optimal oxygenation and role of free radicals in PPHN. Free Radic Biol Med. 2019 10; 142:97-106. Wedgwood S, Steinhorn RH, Lakshminrusimha S. PMID: 30995536.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    24. Drugs for the Prevention and Treatment of Bronchopulmonary Dysplasia. Clin Perinatol. 2019 06; 46(2):291-310. Mandell EW, Kratimenos P, Abman SH, Steinhorn RH. PMID: 31010561.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    25. Monitoring Gas Exchange During Hypothermia for Hypoxic-Ischemic Encephalopathy. Pediatr Crit Care Med. 2019 02; 20(2):166-171. Afzal B, Chandrasekharan P, Tancredi DJ, Russell J, Steinhorn RH, Lakshminrusimha S. PMID: 30720647.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    26. Making noise about high frequency ventilators. J Pediatr. 2019 01; 204:2. Steinhorn RH. PMID: 30579465.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Somatic growth and the risks of bronchopulmonary dysplasia and pulmonary hypertension: connecting epidemiology and physiology 1. Can J Physiol Pharmacol. 2019 Mar; 97(3):197-205. Underwood MA, Wedgwood S, Lakshminrusimha S, Steinhorn RH. PMID: 30512966.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    28. Trends in PDA treatment: is less really more? J Pediatr. 2018 12; 203:2. Steinhorn RH. PMID: 30470376.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. An update on the diagnosis and management of bronchopulmonary dysplasia (BPD)-associated pulmonary hypertension. Semin Perinatol. 2018 11; 42(7):432-443. Berkelhamer SK, Mestan KK, Steinhorn R. PMID: 30384985.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    30. Helping NICU parents face the future. J Pediatr. 2018 09; 200:1-2. Steinhorn RH. PMID: 30144915.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Umbilical cord blood metabolomics reveal distinct signatures of dyslipidemia prior to bronchopulmonary dysplasia and pulmonary hypertension. . 2018 11 01; 315(5):L870-L881. La Frano MR, Fahrmann JF, Grapov D, Pedersen TL, Newman JW, Fiehn O, Underwood MA, Mestan K, Steinhorn RH, Wedgwood S. PMID: 30113229.
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    32. Enhancing the Development and Retention of Physician-Scientists in Academic Pediatrics: Strategies for Success. J Pediatr. 2018 09; 200:277-284. Alvira CM, Steinhorn RH, Balistreri WF, Fineman JR, Oishi PE, Padbury JF, Kinsella JP, Abman SH. PMID: 30055815.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    33. Goldilocks in the NICU-can oxygen be titrated "just right?" J Pediatr. 2018 06; 197:4. Steinhorn RH. PMID: 29801546.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. The Left Ventricle in Congenital Diaphragmatic Hernia: Implications for the Management of Pulmonary Hypertension. J Pediatr. 2018 06; 197:17-22. Kinsella JP, Steinhorn RH, Mullen MP, Hopper RK, Keller RL, Ivy DD, Austin ED, Krishnan US, Rosenzweig EB, Fineman JR, Everett AD, Hanna BD, Humpl T, Raj JU, Abman SH, Pediatric Pulmonary Hypertension Network (PPHNet) . PMID: 29628412.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    35. Bronchopulmonary Dysplasia: Executive Summary of a Workshop. J Pediatr. 2018 06; 197:300-308. Higgins RD, Jobe AH, Koso-Thomas M, Bancalari E, Viscardi RM, Hartert TV, Ryan RM, Kallapur SG, Steinhorn RH, Konduri GG, Davis SD, Thebaud B, Clyman RI, Collaco JM, Martin CR, Woods JC, Finer NN, Raju TNK. PMID: 29551318.
      View in: PubMed   Mentions: 85     Fields:    Translation:Humans
    36. Congenital diaphragmatic hernia: is the heart the problem? J Pediatr. 2017 12; 191:3. Steinhorn RH. PMID: 29173318.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    37. Chronic Pulmonary Insufficiency of Prematurity: Developing Optimal Endpoints for Drug Development. J Pediatr. 2017 12; 191:15-21.e1. Steinhorn R, Davis JM, Göpel W, Jobe A, Abman S, Laughon M, Bancalari E, Aschner J, Ballard R, Greenough A, Storari L, Thomson M, Ariagno RL, Fabbri L, Turner MA, International Neonatal Consortium . PMID: 29173299.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    38. When does BPD begin? J Pediatr. 2017 08; 187:3. Steinhorn R. PMID: 28750762.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    39. Can We Define Bronchopulmonary Dysplasia? J Pediatr. 2017 09; 188:19-23. Jobe AH, Steinhorn R. PMID: 28705654.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    40. Evaluation and Management of Pulmonary Hypertension in Children with Bronchopulmonary Dysplasia. J Pediatr. 2017 09; 188:24-34.e1. Krishnan U, Feinstein JA, Adatia I, Austin ED, Mullen MP, Hopper RK, Hanna B, Romer L, Keller RL, Fineman J, Steinhorn R, Kinsella JP, Ivy DD, Rosenzweig EB, Raj U, Humpl T, Abman SH, Pediatric Pulmonary Hypertension Network (PPHNet) . PMID: 28645441.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    41. Do data give prospective NICU parents what they need most? J Pediatr. 2017 02; 181:2-3. Steinhorn RH. PMID: 28129872.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    42. The Randomized, Controlled Trial of Late Surfactant: Effects on Respiratory Outcomes at 1-Year Corrected Age. J Pediatr. 2017 04; 183:19-25.e2. Keller RL, Eichenwald EC, Hibbs AM, Rogers EE, Wai KC, Black DM, Ballard PL, Asselin JM, Truog WE, Merrill JD, Mammel MC, Steinhorn RH, Ryan RM, Durand DJ, Bendel CM, Bendel-Stenzel EM, Courtney SE, Dhanireddy R, Hudak ML, Koch FR, Mayock DE, McKay VJ, Helderman J, Porta NF, Wadhawan R, Palermo L, Ballard RA, TOLSURF Study Group . PMID: 28100402.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    43. The neonatal respiratory exam: Have we lost our edge? J Pediatr. 2016 Nov; 178:1-2. Steinhorn RH. PMID: 27788832.
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    44. Mastering the golden minute. J Pediatr. 2016 Nov; 178:1. deRegnier RA, Steinhorn RH. PMID: 27788833.
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    45. Making the most of the single-family-room NICU. J Pediatr. 2016 Oct; 177:1-2. Steinhorn RH. PMID: 27666071.
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    46. Neonatal intubation training: the patient comes first. J Pediatr. 2016 Oct; 177:3. Steinhorn RH. PMID: 27666075.
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    47. After the NICU: helping parents achieve the best outcomes. J Pediatr. 2016 Sep; 176:1-4. Steinhorn RH, deRegnier RA. PMID: 27568243.
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    48. Postnatal growth restriction augments oxygen-induced pulmonary hypertension in a neonatal rat model of bronchopulmonary dysplasia. Pediatr Res. 2016 12; 80(6):894-902. Wedgwood S, Warford C, Agvateesiri SC, Thai P, Berkelhamer SK, Perez M, Underwood MA, Steinhorn RH. PMID: 27509009.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    49. Bosentan as Adjunctive Therapy for Persistent Pulmonary Hypertension of the Newborn: Results of the Randomized Multicenter Placebo-Controlled Exploratory Trial. J Pediatr. 2016 Oct; 177:90-96.e3. Steinhorn RH, Fineman J, Kusic-Pajic A, Cornelisse P, Gehin M, Nowbakht P, Pierce CM, Beghetti M, FUTURE-4 study investigators . PMID: 27502103.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    50. Interaction of Target Oxygen Saturation, Bronchopulmonary Dysplasia, and Pulmonary Hypertension in Small for Gestational Age Preterm Neonates. JAMA Pediatr. 2016 08 01; 170(8):807-8. Lakshminrusimha S, Manja V, Steinhorn RH. PMID: 27270828.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    51. Advances in Neonatal Pulmonary Hypertension. Neonatology. 2016; 109(4):334-44. Steinhorn RH. PMID: 27251312.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    52. When should we predict outcomes for extreme prematurity? J Pediatr. 2016 06; 173:1-3. Steinhorn RH. PMID: 27234276.
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    53. Math at work: a new neonatal calculator to predict weight loss. J Pediatr. 2016 06; 173:1-3. Steinhorn RH. PMID: 27234278.
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    54. New Thoughts about the Origin of Plexiform Lesions. Am J Respir Crit Care Med. 2016 Mar 01; 193(5):484-5. St Croix CM, Steinhorn RH. PMID: 26930432.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    55. The myocardial architecture changes in persistent pulmonary hypertension of the newborn in an ovine animal model. Pediatr Res. 2016 Apr; 79(4):565-74. Agger P, Lakshminrusimha S, Laustsen C, Gugino S, Frandsen JR, Smerup M, Anderson RH, Hjortdal V, Steinhorn RH. PMID: 26679151.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    56. Recommendations for the Use of Inhaled Nitric Oxide Therapy in Premature Newborns with Severe Pulmonary Hypertension. J Pediatr. 2016 Mar; 170:312-4. Kinsella JP, Steinhorn RH, Krishnan US, Feinstein JA, Adatia I, Austin ED, Rosenzweig EB, Everett AD, Fineman JR, Hanna BD, Hopper RK, Humpl T, Ivy DD, Keller RL, Mullen MP, Raj JU, Wessel DL, Abman SH. PMID: 26703869.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    57. Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society. Circulation. 2015 Nov 24; 132(21):2037-99. Abman SH, Hansmann G, Archer SL, Ivy DD, Adatia I, Chung WK, Hanna BD, Rosenzweig EB, Raj JU, Cornfield D, Stenmark KR, Steinhorn R, Thébaud B, Fineman JR, Kuehne T, Feinstein JA, Friedberg MK, Earing M, Barst RJ, Keller RL, Kinsella JP, Mullen M, Deterding R, Kulik T, Mallory G, Humpl T, Wessel DL, American Heart Association Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitatio . PMID: 26534956.
      View in: PubMed   Mentions: 190     Fields:    Translation:Humans
    58. Randomized Trial of Late Surfactant Treatment in Ventilated Preterm Infants Receiving Inhaled Nitric Oxide. J Pediatr. 2016 Jan; 168:23-29.e4. Ballard RA, Keller RL, Black DM, Ballard PL, Merrill JD, Eichenwald EC, Truog WE, Mammel MC, Steinhorn RH, Rogers EE, Ryan RM, Durand DJ, Asselin JM, Bendel CM, Bendel-Stenzel EM, Courtney SE, Dhanireddy R, Hudak ML, Koch FR, Mayock DE, McKay VJ, O'Shea TM, Porta NF, Wadhawan R, Palermo L, TOLSURF Study Group . PMID: 26500107.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    59. Addressing health disparities in rural communities using telehealth. Pediatr Res. 2016 Jan; 79(1-2):169-76. Marcin JP, Shaikh U, Steinhorn RH. PMID: 26466080.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    60. Cyclic stretch stimulates mitochondrial reactive oxygen species and Nox4 signaling in pulmonary artery smooth muscle cells. . 2015 Jul 15; 309(2):L196-203. Wedgwood S, Lakshminrusimha S, Schumacker PT, Steinhorn RH. PMID: 26024892.
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    61. Right ventricular cyclic nucleotide signaling is decreased in hyperoxia-induced pulmonary hypertension in neonatal mice. . 2015 Jun 15; 308(12):H1575-82. Heilman RP, Lagoski MB, Lee KJ, Taylor JM, Kim GA, Berkelhamer SK, Steinhorn RH, Farrow KN. PMID: 25862831.
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    62. Hypoxia inducible factor signaling and experimental persistent pulmonary hypertension of the newborn. Front Pharmacol. 2015; 6:47. Wedgwood S, Lakshminrusimha S, Schumacker PT, Steinhorn RH. PMID: 25814954.
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    63. Pulmonary hypertension in premature infants. Sharpening the tools of detection. Am J Respir Crit Care Med. 2015 Jan 01; 191(1):12-4. Farrow KN, Steinhorn RH. PMID: 25551345.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    64. [Pediatric pulmonary hypertension]. Turk Kardiyol Dern Ars. 2014 Oct; 42 Suppl 1:153-64. Ivy DD, Abman SH, Barst RJ, Berger RM, Bonnet D, Fleming TR, Haworth SG, Raj JU, Rosenzweig EB, Neick IS, Steinhorn RH, Beghetti M. PMID: 25697042.
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    65. Noninvasive inhaled nitric oxide does not prevent bronchopulmonary dysplasia in premature newborns. J Pediatr. 2014 Dec; 165(6):1104-1108.e1. Kinsella JP, Cutter GR, Steinhorn RH, Nelin LD, Walsh WF, Finer NN, Abman SH. PMID: 25063725.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    66. Inhaled nitric oxide increases urinary nitric oxide metabolites and cyclic guanosine monophosphate in premature infants: relationship to pulmonary outcome. Am J Perinatol. 2015 Feb; 32(3):225-32. Ballard PL, Keller RL, Black DM, Durand DJ, Merrill JD, Eichenwald EC, Truog WE, Mammel MC, Steinhorn R, Ryan RM, Courtney SE, Horneman H, Ballard RA, Investigators of TOLSURF Pilot and TOLSURF . PMID: 24968129.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    67. Hydrocortisone normalizes phosphodiesterase-5 activity in pulmonary artery smooth muscle cells from lambs with persistent pulmonary hypertension of the newborn. Pulm Circ. 2014 Mar; 4(1):71-81. Perez M, Wedgwood S, Lakshminrusimha S, Farrow KN, Steinhorn RH. PMID: 25006423.
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    68. Role of reactive oxygen species in neonatal pulmonary vascular disease. Antioxid Redox Signal. 2014 Nov 01; 21(13):1926-42. Wedgwood S, Steinhorn RH. PMID: 24350610.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    69. Disrupted pulmonary artery cyclic guanosine monophosphate signaling in mice with hyperoxia-induced pulmonary hypertension. Am J Respir Cell Mol Biol. 2014 Feb; 50(2):369-78. Lee KJ, Berkelhamer SK, Kim GA, Taylor JM, O'Shea KM, Steinhorn RH, Farrow KN. PMID: 24032519.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    70. Regulation of hypoxia-induced pulmonary hypertension by vascular smooth muscle hypoxia-inducible factor-1a. Am J Respir Crit Care Med. 2014 Feb 01; 189(3):314-24. Ball MK, Waypa GB, Mungai PT, Nielsen JM, Czech L, Dudley VJ, Beussink L, Dettman RW, Berkelhamer SK, Steinhorn RH, Shah SJ, Schumacker PT. PMID: 24251580.
      View in: PubMed   Mentions: 97     Fields:    Translation:Animals
    71. Pediatric pulmonary hypertension. J Am Coll Cardiol. 2013 Dec 24; 62(25 Suppl):D117-26. Ivy DD, Abman SH, Barst RJ, Berger RM, Bonnet D, Fleming TR, Haworth SG, Raj JU, Rosenzweig EB, Schulze Neick I, Steinhorn RH, Beghetti M. PMID: 24355636.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimals
    72. Extracorporeal membrane oxygenation in resource-limited countries. Pediatr Crit Care Med. 2013 Nov; 14(9):900-2. Keller RL, Steinhorn RH. PMID: 24226558.
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    73. Diagnosis and treatment of pulmonary hypertension in infancy. Early Hum Dev. 2013 Nov; 89(11):865-74. Steinhorn RH. PMID: 24083892.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    74. Pulmonary hypertension in bronchopulmonary dysplasia. Semin Perinatol. 2013 Apr; 37(2):124-31. Berkelhamer SK, Mestan KK, Steinhorn RH. PMID: 23582967.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    75. Role of BCL2-associated athanogene 1 in differential sensitivity of human endothelial cells to glucocorticoids. Arterioscler Thromb Vasc Biol. 2013 May; 33(5):1046-55. Mata-Greenwood E, Stewart JM, Steinhorn RH, Pearce WJ. PMID: 23493285.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    76. Developmental differences in hyperoxia-induced oxidative stress and cellular responses in the murine lung. Free Radic Biol Med. 2013 Aug; 61:51-60. Berkelhamer SK, Kim GA, Radder JE, Wedgwood S, Czech L, Steinhorn RH, Schumacker PT. PMID: 23499839.
      View in: PubMed   Mentions: 38     Fields:    Translation:Animals
    77. Antioxidant therapy for the treatment of pulmonary hypertension. Antioxid Redox Signal. 2013 May 10; 18(14):1723-6. Suzuki YJ, Steinhorn RH, Gladwin MT. PMID: 23330936.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    78. Cyclic stretch induces inducible nitric oxide synthase and soluble guanylate cyclase in pulmonary artery smooth muscle cells. Int J Mol Sci. 2013 Feb 21; 14(2):4334-48. Shah MR, Wedgwood S, Czech L, Kim GA, Lakshminrusimha S, Schumacker PT, Steinhorn RH, Farrow KN. PMID: 23429274.
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    79. Increased p22(phox)/Nox4 expression is involved in remodeling through hydrogen peroxide signaling in experimental persistent pulmonary hypertension of the newborn. Antioxid Redox Signal. 2013 May 10; 18(14):1765-76. Wedgwood S, Lakshminrusimha S, Czech L, Schumacker PT, Steinhorn RH. PMID: 23244636.
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    80. Beyond pulmonary hypertension: sildenafil for chronic lung disease of prematurity. Am J Respir Cell Mol Biol. 2013 Feb; 48(2):iii-v. Steinhorn RH, Kinsella JP, Abman SH. PMID: 23378489.
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    81. Inodilators in nitric oxide resistant persistent pulmonary hypertension of the newborn. Pediatr Crit Care Med. 2013 Jan; 14(1):107-9. Lakshminrusimha S, Steinhorn RH. PMID: 23295841.
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    82. Implications of the U.S. Food and Drug Administration warning against the use of sildenafil for the treatment of pediatric pulmonary hypertension. Am J Respir Crit Care Med. 2013 Mar 15; 187(6):572-5. Abman SH, Kinsella JP, Rosenzweig EB, Krishnan U, Kulik T, Mullen M, Wessel DL, Steinhorn R, Adatia I, Hanna B, Feinstein J, Fineman J, Raj U, Humpl T, Pediatric Pulmonary Hypertension Network (PPHNet) . PMID: 23220921.
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    83. Late administration of surfactant replacement therapy increases surfactant protein-B content: a randomized pilot study. Pediatr Res. 2012 Dec; 72(6):613-9. Keller RL, Merrill JD, Black DM, Steinhorn RH, Eichenwald EC, Durand DJ, Ryan RM, Truog WE, Courtney SE, Ballard PL, Ballard RA. PMID: 23037875.
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    84. Pharmacotherapy for pulmonary hypertension. Pediatr Clin North Am. 2012 Oct; 59(5):1129-46. Steinhorn RH. PMID: 23036248.
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    85. Inhaled nitric oxide for preterm infants: a Marksman's approach. J Pediatr. 2012 Sep; 161(3):379-80. Ball MK, Steinhorn RH. PMID: 22727871.
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    86. Brief hyperoxia increases mitochondrial oxidation and increases phosphodiesterase 5 activity in fetal pulmonary artery smooth muscle cells. Antioxid Redox Signal. 2012 Aug 01; 17(3):460-70. Farrow KN, Lee KJ, Perez M, Schriewer JM, Wedgwood S, Lakshminrusimha S, Smith CL, Steinhorn RH, Schumacker PT. PMID: 22229392.
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    87. Developments in imaging: 'a huge difference in primary care'. Pediatr Ann. 2012 Mar; 41(3):122-3. Donaldson JS, Yogev R, Shulman ST, Selva TJ, Gersony WM, Steinhorn RH, Block SL. PMID: 22420386.
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    88. Pulmonary vasodilator therapy in the NICU: inhaled nitric oxide, sildenafil, and other pulmonary vasodilating agents. Clin Perinatol. 2012 Mar; 39(1):149-64. Porta NF, Steinhorn RH. PMID: 22341543.
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    89. Apocynin improves oxygenation and increases eNOS in persistent pulmonary hypertension of the newborn. . 2012 Mar 15; 302(6):L616-26. Wedgwood S, Lakshminrusimha S, Farrow KN, Czech L, Gugino SF, Soares F, Russell JA, Steinhorn RH. PMID: 22198908.
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    90. Hydrocortisone normalizes oxygenation and cGMP regulation in lambs with persistent pulmonary hypertension of the newborn. . 2012 Mar 15; 302(6):L595-603. Perez M, Lakshminrusimha S, Wedgwood S, Czech L, Gugino SF, Russell JA, Farrow KN, Steinhorn RH. PMID: 22198909.
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    91. Fetal origins of neonatal lung disease: understanding the pathogenesis of bronchopulmonary dysplasia. . 2011 Dec; 301(6):L858-9. Mestan KK, Steinhorn RH. PMID: 21964401.
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    92. Pre-term neonate with intestinal failure, feeding issues. Pediatr Ann. 2011 Aug; 40(8):404-6; quiz 407-9. Robinson DT, Steinhorn RH. PMID: 21815602.
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    93. Pulmonary hemodynamics and vascular reactivity in asphyxiated term lambs resuscitated with 21 and 100% oxygen. J Appl Physiol (1985). 2011 Nov; 111(5):1441-7. Lakshminrusimha S, Steinhorn RH, Wedgwood S, Savorgnan F, Nair J, Mathew B, Gugino SF, Russell JA, Swartz DD. PMID: 21799125.
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    94. A randomized study of a monoclonal antibody (pagibaximab) to prevent staphylococcal sepsis. Pediatrics. 2011 Aug; 128(2):271-9. Weisman LE, Thackray HM, Steinhorn RH, Walsh WF, Lassiter HA, Dhanireddy R, Brozanski BS, Palmer KG, Trautman MS, Escobedo M, Meissner HC, Sasidharan P, Fretz J, Kokai-Kun JF, Kramer WG, Fischer GW, Mond JJ. PMID: 21788224.
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    95. Prematurity and congenital heart disease. World J Pediatr Congenit Heart Surg. 2011 Jul 01; 2(3):457-67. Costello JM, McQuillen PS, Claud EC, Steinhorn RH. PMID: 23803997.
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    96. Inhaled nitric oxide and bronchopulmonary dysplasia. Pediatrics. 2011 Jul; 128(1):e255-6; author reply e256-7. Steinhorn RH, Shaul PW, deRegnier RA, Kennedy KA. PMID: 21725058.
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    97. Every week matters. J Pediatr. 2011 Aug; 159(2):177-8. Steinhorn RH. PMID: 21514599.
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    98. Hydrogen peroxide regulates extracellular superoxide dismutase activity and expression in neonatal pulmonary hypertension. Antioxid Redox Signal. 2011 Sep 15; 15(6):1497-506. Wedgwood S, Lakshminrusimha S, Fukai T, Russell JA, Schumacker PT, Steinhorn RH. PMID: 20919937.
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    99. Alveolar capillary dysplasia. Am J Respir Crit Care Med. 2011 Jul 15; 184(2):172-9. Bishop NB, Stankiewicz P, Steinhorn RH. PMID: 21471096.
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    100. Therapeutic approaches using nitric oxide in infants and children. Free Radic Biol Med. 2011 Sep 01; 51(5):1027-34. Steinhorn RH. PMID: 21237265.
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    101. Phosphodiesterases: emerging therapeutic targets for neonatal pulmonary hypertension. Handb Exp Pharmacol. 2011; (204):251-77. Farrow KN, Steinhorn RH. PMID: 21695644.
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    102. In-house neonatology: what are we waiting for? Am J Respir Crit Care Med. 2010 Sep 15; 182(6):728-9. Kourembanas S, Steinhorn R. PMID: 20833827.
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    103. Mitochondrial oxidant stress increases PDE5 activity in persistent pulmonary hypertension of the newborn. Respir Physiol Neurobiol. 2010 Dec 31; 174(3):272-81. Farrow KN, Wedgwood S, Lee KJ, Czech L, Gugino SF, Lakshminrusimha S, Schumacker PT, Steinhorn RH. PMID: 20804862.
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    104. SOD and inhaled nitric oxide normalize phosphodiesterase 5 expression and activity in neonatal lambs with persistent pulmonary hypertension. . 2010 Jul; 299(1):L109-16. Farrow KN, Lakshminrusimha S, Czech L, Groh BS, Gugino SF, Davis JM, Russell JA, Steinhorn RH. PMID: 20400523.
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    105. Neonatal pulmonary hypertension. Pediatr Crit Care Med. 2010 Mar; 11(2 Suppl):S79-84. Steinhorn RH. PMID: 20216169.
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    106. Intravenous sildenafil in the treatment of neonates with persistent pulmonary hypertension. J Pediatr. 2009 Dec; 155(6):841-847.e1. Steinhorn RH, Kinsella JP, Pierce C, Butrous G, Dilleen M, Oakes M, Wessel DL. PMID: 19836028.
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    107. Regulation of phosphodiesterase 3 in the pulmonary arteries during the perinatal period in sheep. Pediatr Res. 2009 Dec; 66(6):682-7. Chen B, Lakshminrusimha S, Czech L, Groh BS, Gugino SF, Russell JA, Farrow KN, Steinhorn RH. PMID: 19707176.
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    108. Oxygen concentration and pulmonary hemodynamics in newborn lambs with pulmonary hypertension. Pediatr Res. 2009 Nov; 66(5):539-44. Lakshminrusimha S, Swartz DD, Gugino SF, Ma CX, Wynn KA, Ryan RM, Russell JA, Steinhorn RH. PMID: 19680165.
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    109. Milrinone enhances relaxation to prostacyclin and iloprost in pulmonary arteries isolated from lambs with persistent pulmonary hypertension of the newborn. Pediatr Crit Care Med. 2009 Jan; 10(1):106-12. Lakshminrusimha S, Porta NF, Farrow KN, Chen B, Gugino SF, Kumar VH, Russell JA, Steinhorn RH. PMID: 19057444.
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    110. Medical and financial impact of a neonatal extracorporeal membrane oxygenation referral center in the nitric oxide era. Pediatrics. 2009 Jan; 123(1):e17-24. Pawlik TD, Porta NF, Steinhorn RH, Ogata E, deRegnier RA. PMID: 19064612.
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    111. Inhaled NO in the experimental setting. Early Hum Dev. 2008 Nov; 84(11):717-23. Porta NF, Steinhorn RH. PMID: 18947945.
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    112. Superoxide dismutase restores eNOS expression and function in resistance pulmonary arteries from neonatal lambs with persistent pulmonary hypertension. . 2008 Dec; 295(6):L979-87. Farrow KN, Lakshminrusimha S, Reda WJ, Wedgwood S, Czech L, Gugino SF, Davis JM, Russell JA, Steinhorn RH. PMID: 18790993.
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    113. Evaluation and management of the cyanotic neonate. Clin Pediatr Emerg Med. 2008 Sep; 9(3):169-175. Steinhorn RH. PMID: 19727322.
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    114. Hyperoxia increases phosphodiesterase 5 expression and activity in ovine fetal pulmonary artery smooth muscle cells. Circ Res. 2008 Feb 01; 102(2):226-33. Farrow KN, Groh BS, Schumacker PT, Lakshminrusimha S, Czech L, Gugino SF, Russell JA, Steinhorn RH. PMID: 17991881.
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    115. Pulmonary hemodynamics in neonatal lambs resuscitated with 21%, 50%, and 100% oxygen. Pediatr Res. 2007 Sep; 62(3):313-8. Lakshminrusimha S, Russell JA, Steinhorn RH, Swartz DD, Ryan RM, Gugino SF, Wynn KA, Kumar VH, Mathew B, Kirmani K, Morin FC. PMID: 17622960.
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    116. The role of nitric oxide synthase-derived reactive oxygen species in the altered relaxation of pulmonary arteries from lambs with increased pulmonary blood flow. . 2007 Sep; 293(3):H1491-7. Lakshminrusimha S, Wiseman D, Black SM, Russell JA, Gugino SF, Oishi P, Steinhorn RH, Fineman JR. PMID: 17513498.
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    117. Use of inhaled nitric oxide in the preterm infant. Curr Opin Pediatr. 2007 Apr; 19(2):137-41. Steinhorn RH, Porta NF. PMID: 17496754.
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    118. Evidence-based guidelines for cardiovascular disease prevention in women: 2007 update. J Am Coll Cardiol. 2007 Mar 20; 49(11):1230-50. Mosca L, Banka CL, Benjamin EJ, Berra K, Bushnell C, Dolor RJ, Ganiats TG, Gomes AS, Gornik HL, Gracia C, Gulati M, Haan CK, Judelson DR, Keenan N, Kelepouris E, Michos ED, Newby LK, Oparil S, Ouyang P, Oz MC, Petitti D, Pinn VW, Redberg RF, Scott R, Sherif K, Smith SC, Sopko G, Steinhorn RH, Stone NJ, Taubert KA, Todd BA, Urbina E, Wenger NK, Expert Panel/Writing Group , American Academy of Physician Assistants , American Association for Clinical Chemistry , American Association of Cardiovascular and Pulmonary Rehabilitation , American College of Chest Physicians , American College of Emergency Physicians , American Diabetes Association , American Geriatrics Society , American Society for Preventive Cardiology , American Society of Echocardiography , American Society of Nuclear Cardiology , Association of Women's Health, Obstetric and Neonatal Nurses , Global Alliance for Women's Health , Mended Hearts, Inc , National Black Nurses Association , National Black Women's Health Imperative , National Women's Health Resource Center , North American Menopause Society , Partnership for Gender-Specific Medicine at Columbia University , Preventive Cardiovascular Nurses Association , Society for Vascular Medicine and Biology , Society for Women's Health Research , Society of Geriatric Cardiology , Women in Thoracic Surgery , WomenHeart: the National Coalition for Women with Heart Disease . PMID: 17367675.
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    119. Evidence-based guidelines for cardiovascular disease prevention in women: 2007 update. Circulation. 2007 Mar 20; 115(11):1481-501. Mosca L, Banka CL, Benjamin EJ, Berra K, Bushnell C, Dolor RJ, Ganiats TG, Gomes AS, Gornik HL, Gracia C, Gulati M, Haan CK, Judelson DR, Keenan N, Kelepouris E, Michos ED, Newby LK, Oparil S, Ouyang P, Oz MC, Petitti D, Pinn VW, Redberg RF, Scott R, Sherif K, Smith SC, Sopko G, Steinhorn RH, Stone NJ, Taubert KA, Todd BA, Urbina E, Wenger NK, Expert Panel/Writing Group , American Heart Association , American Academy of Family Physicians , American College of Obstetricians and Gynecologists , American College of Cardiology Foundation , Society of Thoracic Surgeons , American Medical Women's Association , Centers for Disease Control and Prevention , Office of Research on Women's Health , Association of Black Cardiologists , American College of Physicians , World Heart Federation , National Heart, Lung, and Blood Institute , American College of Nurse Practitioners . PMID: 17309915.
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    120. Superoxide dismutase improves oxygenation and reduces oxidation in neonatal pulmonary hypertension. Am J Respir Crit Care Med. 2006 Dec 15; 174(12):1370-7. Lakshminrusimha S, Russell JA, Wedgwood S, Gugino SF, Kazzaz JA, Davis JM, Steinhorn RH. PMID: 17008638.
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    121. Neonatal extracorporeal life support: impact of new therapies on survival. J Pediatr. 2006 May; 148(5):595-9. Fliman PJ, deRegnier RA, Kinsella JP, Reynolds M, Rankin LL, Steinhorn RH. PMID: 16737868.
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    122. Ovine bronchial-derived relaxing factor: changes with development and hyperoxic ventilation. J Appl Physiol (1985). 2006 Jul; 101(1):135-9. Lakshminrusimha S, Morin FC, Steinhorn RH, Gugino SF, Ryan RM, Kumar VH, Russell JA. PMID: 16575021.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    123. Pulmonary arterial contractility in neonatal lambs increases with 100% oxygen resuscitation. Pediatr Res. 2006 Jan; 59(1):137-41. Lakshminrusimha S, Russell JA, Steinhorn RH, Ryan RM, Gugino SF, Morin FC, Swartz DD, Kumar VH. PMID: 16326983.
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    124. eNOS function is developmentally regulated: uncoupling of eNOS occurs postnatally. . 2006 Feb; 290(2):L232-41. Mata-Greenwood E, Jenkins C, Farrow KN, Konduri GG, Russell JA, Lakshminrusimha S, Black SM, Steinhorn RH. PMID: 16143585.
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    125. Selective type 5 phosphodiesterase inhibition alters pulmonary hemodynamics and lung liquid production in near-term fetal lambs. J Appl Physiol (1985). 2005 Dec; 99(6):2331-6. Dukarm RC, Steinhorn RH, Russell JA, Lakshminrusimha S, Swartz D, Cummings JJ. PMID: 16123210.
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    126. Inhaled nitric oxide for premature infants with severe respiratory failure. N Engl J Med. 2005 Jul 07; 353(1):13-22. Van Meurs KP, Wright LL, Ehrenkranz RA, Lemons JA, Ball MB, Poole WK, Perritt R, Higgins RD, Oh W, Hudak ML, Laptook AR, Shankaran S, Finer NN, Carlo WA, Kennedy KA, Fridriksson JH, Steinhorn RH, Sokol GM, Konduri GG, Aschner JL, Stoll BJ, D'Angio CT, Stevenson DK, Preemie Inhaled Nitric Oxide Study . PMID: 16000352.
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    127. Increased hydrogen peroxide downregulates soluble guanylate cyclase in the lungs of lambs with persistent pulmonary hypertension of the newborn. . 2005 Oct; 289(4):L660-6. Wedgwood S, Steinhorn RH, Bunderson M, Wilham J, Lakshminrusimha S, Brennan LA, Black SM. PMID: 15937064.
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    128. The diseases treated with ECMO: focus on PPHN. Semin Perinatol. 2005 Feb; 29(1):8-14. Farrow KN, Fliman P, Steinhorn RH. PMID: 15921147.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    129. Connecting the cells: vascular differentiation via homeobox genes and extracellular matrix in the distal lung. Circ Res. 2004 Jun 11; 94(11):1406-7. Dettman RW, Steinhorn RH. PMID: 15192035.
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    130. Nitric oxide decreases endothelin-1 secretion through the activation of soluble guanylate cyclase. . 2004 May; 286(5):L984-91. Kelly LK, Wedgwood S, Steinhorn RH, Black SM. PMID: 14695117.
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    131. Emergence of smooth muscle cell endothelin B-mediated vasoconstriction in lambs with experimental congenital heart disease and increased pulmonary blood flow. Circulation. 2003 Sep 30; 108(13):1646-54. Black SM, Mata-Greenwood E, Dettman RW, Ovadia B, Fitzgerald RK, Reinhartz O, Thelitz S, Steinhorn RH, Gerrets R, Hendricks-Munoz K, Ross GA, Bekker JM, Johengen MJ, Fineman JR. PMID: 12963646.
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    132. Alterations in TGF-beta1 expression in lambs with increased pulmonary blood flow and pulmonary hypertension. . 2003 Jul; 285(1):L209-21. Mata-Greenwood E, Meyrick B, Steinhorn RH, Fineman JR, Black SM. PMID: 12665463.
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    133. Increased superoxide generation is associated with pulmonary hypertension in fetal lambs: a role for NADPH oxidase. Circ Res. 2003 Apr 04; 92(6):683-91. Brennan LA, Steinhorn RH, Wedgwood S, Mata-Greenwood E, Roark EA, Russell JA, Black SM. PMID: 12609968.
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    134. Paracrine role of soluble guanylate cyclase and type III nitric oxide synthase in ovine fetal pulmonary circulation: a double labeling immunohistochemical study. Histochem Cell Biol. 2003 Feb; 119(2):125-30. Tzao C, Nickerson PA, Russell JA, Noble BK, Steinhorn RH. PMID: 12610731.
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    135. Inhaled prostacyclin for term infants with persistent pulmonary hypertension refractory to inhaled nitric oxide. J Pediatr. 2002 Dec; 141(6):830-2. Kelly LK, Porta NF, Goodman DM, Carroll CL, Steinhorn RH. PMID: 12461501.
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    136. Alterations in nitric oxide production in 8-week-old lambs with increased pulmonary blood flow. Pediatr Res. 2002 Aug; 52(2):233-44. Black SM, Bekker JM, McMullan DM, Parry AJ, Ovadia B, Reinhartz O, Lakshminrushimha S, Mata-Greenwood E, Steinhorn RH, Fineman JR. PMID: 12149501.
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    137. Type I nitric oxide synthase is decreased in the fetal pulmonary circulation of hypertensive lambs. Pediatr Pulmonol. 2002 Jun; 33(6):437-42. Tzao C, Nickerson PA, Steinhorn RH, Noble BK, Swartz DD, Russell JA. PMID: 12001276.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals