Michael Simmonds

Title(s)Assistant Project Scientist, Center for Energy Research
SchoolVc-research
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Accelerated Hemocompatibility Testing of Rotary Blood Pumps. ASAIO J. 2023 10 01; 69(10):918-923. McNamee AP, Griffith TA, Smith AG, Kuck L, Simmonds MJ. PMID: 37256782.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Modulation of red blood cell nitric oxide synthase phosphorylation in the quiescent and exercising human forearm. Am J Physiol Regul Integr Comp Physiol. 2023 09 01; 325(3):R260-R268. Leo JA, Sabapathy S, Kuck L, Simmonds MJ. PMID: 37424398.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Single-night continuous positive airway pressure treatment improves blood fluid properties in individuals recently diagnosed with obstructive sleep apnoea. Microvasc Res. 2023 07; 148:104549. Bent Z, Kuck L, Sabapathy S, Sriram KB, McNamee AP, Simmonds MJ. PMID: 37192687.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Red Blood Cell Sublethal Damage: Hemocompatibility Is not the Absence of Hemolysis. Transfus Med Rev. 2023 04; 37(2):150723. McNamee AP, Simmonds MJ. PMID: 37031086.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Mitigation effect of cell exclusion on blood damage in spiral groove bearings. J Biomech. 2023 01; 146:111394. Chan CHH, Murashige T, Bieritz SA, Semenzin C, Smith A, Leslie L, Simmonds MJ, Tansley GD. PMID: 36462474.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. Post-fatigue ability to activate muscle is compromised across a wide range of torques during acute hypoxic exposure. Eur J Neurosci. 2022 09; 56(5):4653-4668. McKeown DJ, McNeil CJ, Simmonds MJ, Kavanagh JJ. PMID: 35841186; PMCID: PMC9546238.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Physical Properties of Blood and their Relationship to Clinical Conditions. Front Physiol. 2022; 13:906768. Alexy T, Detterich J, Connes P, Toth K, Nader E, Kenyeres P, Arriola-Montenegro J, Ulker P, Simmonds MJ. PMID: 35874542; PMCID: PMC9298661.
      View in: PubMed   Mentions: 6  
    8. Piezo1 regulates shear-dependent nitric oxide production in human erythrocytes. Am J Physiol Heart Circ Physiol. 2022 07 01; 323(1):H24-H37. Kuck L, Peart JN, Simmonds MJ. PMID: 35559724.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    9. Bovine erythrocytes are poor surrogates for human when exposed to sublethal shear stress. Int J Artif Organs. 2022 Jun; 45(6):580-587. McNamee AP, Kuck L, Simmonds MJ. PMID: 35531705.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    10. Protocol for inspecting blood cell dynamics with a custom ektacytometer-rheometer apparatus. STAR Protoc. 2022 06 17; 3(2):101279. Fitzpatrick T, Simmonds MJ, McNamee AP. PMID: 35434656; PMCID: PMC9006864.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    11. Enhanced Blood Plasma Extraction Utilising Viscoelastic Effects in a Serpentine Microchannel. Biosensors (Basel). 2022 Feb 14; 12(2). Dai Y, Cha H, Simmonds MJ, Fallahi H, An H, Ta HT, Nguyen NT, Zhang J, McNamee AP. PMID: 35200380; PMCID: PMC8869685.
      View in: PubMed   Mentions: 3     Fields:    
    12. Erythrocyte morphological symmetry analysis to detect sublethal trauma in shear flow. Sci Rep. 2021 12 07; 11(1):23566. McNamee AP, Simmonds MJ, Inoue M, Horobin JT, Hakozaki M, Fraser JF, Watanabe N. PMID: 34876652; PMCID: PMC8651737.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    13. Discrete responses of erythrocytes, platelets, and von Willebrand factor to shear. J Biomech. 2022 01; 130:110898. Chan CHH, Simmonds MJ, Fraser KH, Igarashi K, Ki KK, Murashige T, Joseph MT, Fraser JF, Tansley GD, Watanabe N. PMID: 34896790.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    14. Severe acute hypoxia impairs recovery of voluntary muscle activation after sustained submaximal elbow flexion. J Physiol. 2021 12; 599(24):5379-5395. McKeown DJ, McNeil CJ, Brotherton EJ, Simmonds MJ, Kavanagh JJ. PMID: 34761807.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    15. Impact of small fractions of abnormal erythrocytes on blood rheology. Microvasc Res. 2022 01; 139:104261. Kuck L, McNamee AP, Simmonds MJ. PMID: 34624306.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    16. Rate-Pressure Product Responses to Static Contractions Performed at Various Altitudes. High Alt Med Biol. 2021 Jun; 22(2):166-173. Simmonds MJ, Sabapathy S, Hero JM. PMID: 33470884.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Sub-Fractions of Red Blood Cells Respond Differently to Shear Exposure Following Superoxide Treatment. Biology (Basel). 2021 Jan 11; 10(1). Grau M, Kuck L, Dietz T, Bloch W, Simmonds MJ. PMID: 33440902; PMCID: PMC7827655.
      View in: PubMed   Mentions: 1  
    18. Shear Stress and RBC-NOS Serine1177 Phosphorylation in Humans: A Dose Response. Life (Basel). 2021 Jan 08; 11(1). Horobin JT, Sabapathy S, Kuck L, Simmonds MJ. PMID: 33429979; PMCID: PMC7828091.
      View in: PubMed   Mentions:
    19. Ex vivo assessment of erythrocyte tolerance to the HeartWare ventricular assist device operated in three discrete configurations. Artif Organs. 2021 Jun; 45(6):E146-E157. Kuck L, Simmonds MJ, Chan CHH, Pauls JP, Tansley GD, Feldmann F, McNamee AP. PMID: 33236358.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    20. Sublethal Supraphysiological Shear Stress Alters Erythrocyte Dynamics in Subsequent Low-Shear Flows. Biophys J. 2020 12 01; 119(11):2179-2189. McNamee AP, Fitzpatrick T, Tansley GD, Simmonds MJ. PMID: 33130119; PMCID: PMC7732817.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    21. Hemochromatosis alters the sensitivity of red blood cells to mechanical stress. Transfusion. 2020 12; 60(12):2982-2990. Richardson KJ, McNamee AP, Simmonds MJ. PMID: 32945551.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    22. Mechanical sensitivity of red blood cells improves in individuals with hemochromatosis following venesection therapy. Transfusion. 2020 12; 60(12):3001-3009. Richardson KJ, McNamee AP, Simmonds MJ. PMID: 32939772.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsCTClinical Trials
    23. Time course of neuromuscular responses to acute hypoxia during voluntary contractions. Exp Physiol. 2020 11; 105(11):1855-1868. McKeown DJ, McNeil CJ, Simmonds MJ, Kavanagh JJ. PMID: 32869906.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. Beyond oxygen transport: active role of erythrocytes in the regulation of blood flow. Am J Physiol Heart Circ Physiol. 2020 10 01; 319(4):H866-H872. Richardson KJ, Kuck L, Simmonds MJ. PMID: 32857630.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    25. Sublethal mechanical shear stress increases the elastic shear modulus of red blood cells but does not change capillary transit velocity. Microcirculation. 2020 11; 27(8):e12652. McNamee AP, Tansley GD, Simmonds MJ. PMID: 32738159.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    26. Shear-dependent platelet aggregation size. Artif Organs. 2020 Dec; 44(12):1286-1295. Chan CHH, Inoue M, Ki KK, Murashige T, Fraser JF, Simmonds MJ, Tansley GD, Watanabe N. PMID: 32735693; PMCID: PMC7818454.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    27. Calcium dynamically alters erythrocyte mechanical response to shear. Biochim Biophys Acta Mol Cell Res. 2020 11; 1867(11):118802. Kuck L, Peart JN, Simmonds MJ. PMID: 32717279.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    28. Active modulation of human erythrocyte mechanics. Am J Physiol Cell Physiol. 2020 08 01; 319(2):C250-C257. Kuck L, Peart JN, Simmonds MJ. PMID: 32579474.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    29. In Vitro Hemocompatibility Evaluation of Modified Rotary Left to Right Ventricular Assist Devices in Pulmonary Flow Conditions. ASAIO J. 2020 06; 66(6):637-644. Chan CHH, Nandakumar D, Balletti N, Horobin J, Wu EL, Bouquet M, Stephens A, Pauls JP, Tansley G, Fraser JF, Simmonds MJ, Gregory SD. PMID: 31335374.
      View in: PubMed   Mentions: 1     Fields:    
    30. Shear-thinning behaviour of blood in response to active hyperaemia: Implications for the assessment of arterial shear stress-mediated dilatation. Exp Physiol. 2020 02; 105(2):244-257. Leo JA, Simmonds MJ, Sabapathy S. PMID: 31713290.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Red blood cell tolerance to shear stress above and below the subhemolytic threshold. Biomech Model Mechanobiol. 2020 Jun; 19(3):851-860. Horobin JT, Sabapathy S, Simmonds MJ. PMID: 31720887.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    32. Reduced blood oxygen levels induce changes in low-threshold motor unit firing that align with the individual's tolerance to hypoxia. J Neurophysiol. 2019 05 01; 121(5):1664-1671. McKeown DJ, Simmonds MJ, Kavanagh JJ. PMID: 30864856.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    33. Blood damage in ventricular assist devices. Int J Artif Organs. 2019 03; 42(3):111-112. Simmonds M, Thamsen B, Kertzscher U. PMID: 30862276.
      View in: PubMed   Mentions:    Fields:    
    34. Shear Stress Ameliorates Superoxide Impairment to Erythrocyte Deformability With Concurrent Nitric Oxide Synthase Activation. Front Physiol. 2019; 10:36. Kuck L, Grau M, Bloch W, Simmonds MJ. PMID: 30804795; PMCID: PMC6370721.
      View in: PubMed   Mentions: 9  
    35. Shear-stress mediated nitric oxide production within red blood cells: A dose-response. Clin Hemorheol Microcirc. 2019; 71(2):203-214. Horobin JT, Watanabe N, Hakozaki M, Sabapathy S, Simmonds MJ. PMID: 30584130.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    36. A Cross-Sectional Pilot Study to Examine the Criterion Validity of the Modified Shuttle Test-Paeds as a Measure of Cardiorespiratory Fitness in Children. Int J Environ Res Public Health. 2018 10 18; 15(10). Milne N, Simmonds MJ, Hing W. PMID: 30340419; PMCID: PMC6209955.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    37. Red blood cell mechanical sensitivity improves in patients with sickle cell disease undergoing chronic transfusion after prolonged, subhemolytic shear exposure. Transfusion. 2018 12; 58(12):2788-2796. Simmonds MJ, Suriany S, Ponce D, Detterich JA. PMID: 30325033; PMCID: PMC6283667.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsCTClinical Trials
    38. Susceptibility of density-fractionated erythrocytes to subhaemolytic mechanical shear stress. Int J Artif Organs. 2019 Mar; 42(3):151-157. McNamee AP, Richardson K, Horobin J, Kuck L, Simmonds MJ. PMID: 30073884.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    39. Sublethal mechanical trauma alters the electrochemical properties and increases aggregation of erythrocytes. Microvasc Res. 2018 11; 120:1-7. McNamee AP, Tansley GD, Simmonds MJ. PMID: 29803580.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    40. Speed Modulation of the HeartWare HVAD to Assess In Vitro Hemocompatibility of Pulsatile and Continuous Flow Regimes in a Rotary Blood Pump. Artif Organs. 2018 Sep; 42(9):879-890. Horobin JT, Simmonds MJ, Nandakumar D, Gregory SD, Tansley G, Pauls JP, Girnghuber A, Balletti N, Fraser JF. PMID: 29726019.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    41. Haemochromatosis: Pathophysiology and the red blood cell1. Clin Hemorheol Microcirc. 2018; 69(1-2):295-304. Richardson KJ, McNamee AP, Simmonds MJ. PMID: 29660923.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    42. Recovery time course of erythrocyte deformability following exposure to shear is dependent upon conditioning shear stress. Biorheology. 2018; 54(5-6):141-152. Kuck L, Grau M, Simmonds MJ. PMID: 29578460.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    43. Response. Med Sci Sports Exerc. 2017 12; 49(12):2609. Leo JA, Sabapathy S, Simmonds MJ, Cross TJ. PMID: 29135787.
      View in: PubMed   Mentions: 1     Fields:    
    44. Oxidative Stress Increases Erythrocyte Sensitivity to Shear-Mediated Damage. Artif Organs. 2018 Feb; 42(2):184-192. McNamee AP, Horobin JT, Tansley GD, Simmonds MJ. PMID: 28877350.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    45. The Respiratory Compensation Point is Not a Valid Surrogate for Critical Power. Med Sci Sports Exerc. 2017 07; 49(7):1452-1460. Leo JA, Sabapathy S, Simmonds MJ, Cross TJ. PMID: 28166117.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    46. The Effect of Compliant Inflow Cannulae on the Hemocompatibility of Rotary Blood Pump Circuits in an In Vitro Model. Artif Organs. 2017 Oct; 41(10):E118-E128. Pauls JP, Nandakumar D, Horobin J, Prendeville JD, Simmonds MJ, Fraser JF, Tansley G, Gregory SD. PMID: 28621838.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    47. Repetitive Supra-Physiological Shear Stress Impairs Red Blood Cell Deformability and Induces Hemolysis. Artif Organs. 2017 Nov; 41(11):1017-1025. Horobin JT, Sabapathy S, Simmonds MJ. PMID: 28543744.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    48. Physical Properties of Blood Are Altered in Young and Lean Women with Polycystic Ovary Syndrome. PLoS One. 2016; 11(11):e0167290. Simmonds MJ, Milne N, Ong K, Brotherton E, McNamee AP, Horobin J, Sabapathy S. PMID: 27902766; PMCID: PMC5130252.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    49. Regular walking improves plasma protein concentrations that promote blood hyperviscosity in women 65-74 yr with type 2 diabetes. Clin Hemorheol Microcirc. 2016 Nov 25; 64(2):189-198. Simmonds MJ, Sabapathy S, Serre KR, Haseler LJ, Gass GC, Marshall-Gradisnik SM, Minahan CL. PMID: 27258197.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    50. Biphasic impairment of erythrocyte deformability in response to repeated, short duration exposures of supraphysiological, subhaemolytic shear stress. Biorheology. 2016 Nov 09; 53(3-4):137-149. McNamee AP, Tansley GD, Sabapathy S, Simmonds MJ. PMID: 27662271.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    51. Maximal intermittent contractions of the first dorsal interosseous inhibits voluntary activation of the contralateral homologous muscle. J Neurophysiol. 2016 11; 116(5):2272-2280. Kavanagh JJ, Feldman MR, Simmonds MJ. PMID: 27605530; PMCID: PMC5110640.
      View in: PubMed   Mentions: 5     Fields:    
    52. Acute Free-Iron Exposure Does Not Explain the Impaired Haemorheology Associated with Haemochromatosis. PLoS One. 2016; 11(1):e0146448. McNamee AP, Sabapathy S, Singh I, Horobin J, Guerrero J, Simmonds MJ. PMID: 26741993; PMCID: PMC4712145.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    53. Prediction of the level and duration of shear stress exposure that induces subhemolytic damage to erythrocytes. Biorheology. 2016; 53(5-6):237-249. Simmonds MJ, Meiselman HJ. PMID: 28222499.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    54. T helper cell cytokine profiles after endurance exercise. J Interferon Cytokine Res. 2014 Sep; 34(9):699-706. Kakanis MW, Peake J, Brenu EW, Simmonds M, Gray B, Marshall-Gradisnik SM. PMID: 24673178.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    55. Erythrocyte deformability responses to intermittent and continuous subhemolytic shear stress. Biorheology. 2014; 51(2-3):171-85. Simmonds MJ, Atac N, Baskurt OK, Meiselman HJ, Yalcin O. PMID: 24948378.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    56. Nitric oxide, vasodilation and the red blood cell. Biorheology. 2014; 51(2-3):121-34. Simmonds MJ, Detterich JA, Connes P. PMID: 24819865; PMCID: PMC6441278.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    57. Cardiac electrical conduction, autonomic activity and biomarker release during recovery from prolonged strenuous exercise in trained male cyclists. Eur J Appl Physiol. 2014 Jan; 114(1):1-10. Stewart GM, Kavanagh JJ, Koerbin G, Simmonds MJ, Sabapathy S. PMID: 24101255.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    58. Blood rheology and aging. J Geriatr Cardiol. 2013 Sep; 10(3):291-301. Simmonds MJ, Meiselman HJ, Baskurt OK. PMID: 24133519; PMCID: PMC3796705.
      View in: PubMed   Mentions: 51  
    59. Exercise-induced blood lactate increase does not change red blood cell deformability in cyclists. PLoS One. 2013; 8(8):e71219. Simmonds MJ, Connes P, Sabapathy S. PMID: 23940722; PMCID: PMC3733956.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCellsCTClinical Trials
    60. Exercise hemorheology: classical data, recent findings and unresolved issues. Clin Hemorheol Microcirc. 2013; 53(1-2):187-99. Connes P, Simmonds MJ, Brun JF, Baskurt OK. PMID: 23042105.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    61. Blood viscosity and hemodynamics during exercise. Clin Hemorheol Microcirc. 2012; 51(2):101-9. Connes P, Pichon A, Hardy-Dessources MD, Waltz X, Lamarre Y, Simmonds MJ, Tripette J. PMID: 22240371.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    62. Preliminary findings in the heart rate variability and haemorheology response to varied frequency and duration of walking in women 65-74 yr with type 2 diabetes. Clin Hemorheol Microcirc. 2012; 51(2):87-99. Simmonds MJ, Minahan CL, Serre KR, Gass GC, Marshall-Gradisnik SM, Haseler LJ, Sabapathy S. PMID: 22240377.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    63. Assessment of oxidant susceptibility of red blood cells in various species based on cell deformability. Biorheology. 2011; 48(5):293-304. Simmonds MJ, Meiselman HJ, Marshall-Gradisnik SM, Pyne M, Kakanis M, Keane J, Brenu E, Christy R, Baskurt OK. PMID: 22433570.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    64. A comparison of capillary and venous blood sampling methods for the use in haemorheology studies. Clin Hemorheol Microcirc. 2011; 47(2):111-9. Simmonds MJ, Baskurt OK, Meiselman HJ, Marshall-Gradisnik SM. PMID: 21339631.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    65. Cardiovascular dynamics during exercise are related to blood rheology. Clin Hemorheol Microcirc. 2011; 49(1-4):231-41. Simmonds MJ, Tripette J, Sabapathy S, Marshall-Gradisnik SM, Connes P. PMID: 22214694.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    66. Assessment of the hemorheological profile of koala and echidna. Zoology (Jena). 2010 Mar; 113(2):110-7. Baskurt OK, Marshall-Gradisnik S, Pyne M, Simmonds M, Brenu E, Christy R, Meiselman HJ. PMID: 20138490; PMCID: PMC2859317.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    67. Caffeine improves supramaximal cycling but not the rate of anaerobic energy release. Eur J Appl Physiol. 2010 May; 109(2):287-95. Simmonds MJ, Minahan CL, Sabapathy S. PMID: 20082092.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    68. Heart rate variability is related to impaired haemorheology in older women with type 2 diabetes. Clin Hemorheol Microcirc. 2010; 46(1):57-68. Simmonds MJ, Sabapathy S, Gass GC, Marshall-Gradisnik SM, Haseler LJ, Christy RM, Minahan CL. PMID: 20852363.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
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