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Role of the CX3CL1/CX3CR1 axis in iron metabolism and immune regulation during acute Trypanosoma cruzi infection. Front Immunol. 2025; 16:1585883.
Pio S, Menezes TP, Louise V, Costa GP, Oliveira DM, Carlos N, Paula-Gomes S, Perucci LO, Talvani A. PMID: 40936920; PMCID: PMC12420253.
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AnimalsCells
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Plasminogen and plasmin induce specialized proresolving mediators and promote efferocytosis via 5-lipoxygenase. J Thromb Haemost. 2025 Jun; 23(6):1988-1995.
Perucci LO, Carneiro FS, Souza JC, Grossi LC, Souza JAM, Zaidan I, Cardoso C, Lara ES, Felix FB, Baik N, Tavares LP, Soriani FM, Teixeira MM, Parmer RJ, Miles LA, Sousa LP. PMID: 40147777; PMCID: PMC12189466.
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AnimalsCells
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Piperine as an Herbal Alternative for the Prevention of Drug-Induced Liver Damage Caused by Paracetamol. Pharmaceuticals (Basel). 2024 Nov 02; 17(11).
Coelho AM, Queiroz IF, Perucci LO, Menezes TP, Lima WG, Talvani A, Costa DC. PMID: 39598389; PMCID: PMC11597450.
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PubMed Mentions:
1
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Neuroserpin, IL-33 and IL-17A as potential markers of mild symptoms of depressive syndrome in Toxoplasma gondii-infected pregnant women. Front Immunol. 2024; 15:1394456.
Silva ZM, Toledo DNM, Pio S, Machado BAA, Dos Santos PV, Hó FG, Medina YN, Cordeiro PHM, Perucci LO, Pinto KMC, Talvani A. PMID: 38835777; PMCID: PMC11148649.
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4 Fields:
Translation:
HumansAnimals
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The EV antibody database: An interactive database of curated antibodies for extracellular vesicle and nanoparticle research. Extracell Vesicle. 2024 Jun; 3.
Morey A, Ng M, Spanos M, Zhang P, Xu T, Cheung W, Chatterjee E, Gokulnath P, Carnel-Amar N, Soares Chiaretti AL, Nelson C, George J, Luo M, Chakraborty A, Perucci L, Jones JC, Hoff P, Franklin JL, Raffai RL, Das S, Routenberg DA, Nolan JP, Charest A, Laurent LC, Alexander RP. PMID: 38872853; PMCID: PMC11175471.
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3
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Potential of piperine for neuroprotection in sepsis-associated encephalopathy. Life Sci. 2024 Jan 15; 337:122353.
Ferreira FM, Gomes SV, Carvalho LCF, de Alcantara AC, da Cruz Castro ML, Perucci LO, Pio S, Talvani A, de Abreu Vieira PM, Calsavara AJC, Costa DC. PMID: 38104862.
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3 Fields:
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Animals
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Crosstalk between the plasminogen/plasmin system and inflammation resolution. J Thromb Haemost. 2023 10; 21(10):2666-2678.
Perucci LO, Vago JP, Miles LA, Sousa LP. PMID: 37495082; PMCID: PMC10792525.
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5 Fields:
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HumansAnimalsCells
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Plasmin and plasminogen prevent sepsis severity by reducing neutrophil extracellular traps and systemic inflammation. JCI Insight. 2023 04 24; 8(8).
Vago JP, Zaidan I, Perucci LO, Brito LF, Teixeira LC, Silva CMS, Miranda TC, Melo EM, Bruno AS, Queiroz-Junior CM, Sugimoto MA, Tavares LP, Grossi LC, Borges IN, Schneider AH, Baik N, Schneider AH, Talvani A, Ferreira RG, Alves-Filho JC, Nobre V, Teixeira MM, Parmer RJ, Miles LA, Sousa LP. PMID: 36917195; PMCID: PMC10243804.
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14 Fields:
Translation:
AnimalsCells
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Upregulation of IL-33, CCL2, and CXCL16 levels in Brazilian pregnant women infected by Toxoplasma gondii. Acta Trop. 2023 Jul; 243:106931.
Santos PVD, Toledo DNM, Guimarães NS, Perucci LO, Andrade-Neto VF, Talvani A. PMID: 37086937.
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3 Fields:
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HumansAnimalsCells
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The imbalance in the relationship between inflammatory and regulatory cytokines during gestational toxoplasmosis can be harmful to fetuses: A systematic review. Front Immunol. 2023; 14:1074760.
Dos Santos PV, de Toledo DNM, de Souza DMS, Menezes TP, Perucci LO, Silva ZM, Teixeira DC, Vieira EWR, de Andrade-Neto VF, Guimarães NS, Talvani A. PMID: 36742306; PMCID: PMC9889920.
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7 Fields:
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HumansAnimals
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Neuroserpin: A potential biomarker for early-onset severe preeclampsia. Immunobiology. 2023 03; 228(2):152339.
Perucci LO, da Silva SPG, Bearzoti E, de Castro Pinto KM, Alpoim PN, de Barros Pinheiro M, Godoi LC, de Moraes LÂG, de Sousa LP, Sant Ana Dusse LM, Talvani A. PMID: 36680978.
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3 Fields:
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Humans
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The deleterious impact of exposure to different inhaled anesthetics is time dependent. Life Sci. 2022 Nov 15; 309:121004.
Machado-Junior PA, de Souza ABF, Castro TF, Perucci LO, Talvani A, Cangussú SD, Bezerra FS. PMID: 36170891.
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2 Fields:
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Animals
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Piperine as Therapeutic Agent in Paracetamol-Induced Hepatotoxicity in Mice. Pharmaceutics. 2022 Aug 26; 14(9).
Coelho AM, Queiroz IF, Perucci LO, Souza MO, Lima WG, Talvani A, Costa DC. PMID: 36145547; PMCID: PMC9504321.
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PubMed Mentions:
7
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Corrigendum to <'Protein restriction during pregnancy affects lung development and promotes oxidative stress and inflammation in C57 BL/6 mice offspring'> <[Nutrition Volume 101, September 2022, 111682]>. Nutrition. 2022 Oct; 102:111771.
Castro TF, Matos NA, Souza ABF, Costa GP, Perucci LO, Talvani A, Cangussú SD, Chianca Júnior DA, Menezes RCA, Bezerra FS. PMID: 35906112.
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Insights into IL-33 on inflammatory response during in vitro infection by Trypanosoma cruzi. Immunobiology. 2022 07; 227(4):152243.
Oliveira DS, Leite ALJ, Pedrosa TCF, Mota LWR, Costa GP, Souza DMS, Perucci LO, Talvani A. PMID: 35839730.
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1 Fields:
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HumansAnimals
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Protein restriction during pregnancy affects lung development and promotes oxidative stress and inflammation in C57 BL/6 mice offspring. Nutrition. 2022 09; 101:111682.
Castro TF, de Matos NA, de Souza ABF, Costa GP, Perucci LO, Talvani A, Cangussú SD, de Menezes RCA, Bezerra FS. PMID: 35660498.
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2 Fields:
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HumansAnimals
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Temporal analysis of paracetamol-induced hepatotoxicity. Drug Chem Toxicol. 2023 May; 46(3):472-481.
Coelho AM, Queiroz IF, Lima WG, Talvani A, Perucci LO, Oliveira de Souza M, Costa DC. PMID: 35313777.
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5 Fields:
Translation:
Animals
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Fibrinolysis in COVID-19: Impact on Clot Lysis and Modulation of Inflammation. Curr Drug Targets. 2022; 23(17):1578-1592.
Sugimoto MA, Perucci LO, Tavares LP, Teixeira MM, Sousa LP. PMID: 36221881.
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3 Fields:
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HumansCells
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Longitudinal assessment of leukotriene B4, lipoxin A4, and resolvin D1 plasma levels in pregnant women with risk factors for preeclampsia. Clin Biochem. 2021 Dec; 98:24-28.
Perucci LO, de Castro Pinto KM, da Silva SPG, Lage EM, Teixeira PG, Barbosa AS, Alpoim PN, de Sousa LP, Talvani A, Dusse LMS. PMID: 34492288.
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PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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Hepatoprotective, antioxidant, anti-inflammatory, and antiviral activities of silymarin against mayaro virus infection. Antiviral Res. 2021 10; 194:105168.
Ferraz AC, Almeida LT, da Silva Caetano CC, da Silva Menegatto MB, Souza Lima RL, de Senna JPN, de Oliveira Cardoso JM, Perucci LO, Talvani A, Geraldo de Lima W, de Mello Silva B, Barbosa Reis A, de Magalhães JC, Lopes de Brito Magalhães C. PMID: 34437912.
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20 Fields:
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AnimalsCells
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Zika virus induces oxidative stress and decreases antioxidant enzyme activities in vitro and in vivo. Virus Res. 2020 09; 286:198084.
Almeida LT, Ferraz AC, da Silva Caetano CC, da Silva Menegatto MB, Dos Santos Pereira Andrade AC, Lima RLS, Camini FC, Pereira SH, da Silva Pereira KY, de Mello Silva B, Perucci LO, Talvani A, de Magalhães JC, de Brito Magalhães CL. PMID: 32622852.
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23 Fields:
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HumansAnimalsCells
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Association among ACE, ESR1 polymorphisms and preeclampsia in Brazilian pregnant women. Mol Cell Probes. 2019 06; 45:43-47.
Cristina Dos Santos Lopes A, Perucci LO, Gontijo Evangelista FC, Godoi LC, de Paula Sabino A, Gomes KB, Talvani A, Dusse LMS, Alpoim PN. PMID: 31028794.
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3 Fields:
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Humans
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Longitudinal assessment of D-dimer and plasminogen activator inhibitor type-1 plasma levels in pregnant women with risk factors for preeclampsia. Hypertens Pregnancy. 2019 Feb; 38(1):58-63.
Lucena FC, Lage EM, Teixeira PG, Barbosa AS, Diniz R, Lwaleed B, Talvani A, Alpoim PN, Perucci LO, Dusse LMS. PMID: 30760065.
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4 Fields:
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Humans
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Oxidative stress markers and thrombomodulin plasma levels in women with early and late severe preeclampsia. Clin Chim Acta. 2018 Aug; 483:234-238.
Alpoim PN, Perucci LO, Godoi LC, Goulart COL, Dusse LMS. PMID: 29723511.
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6 Fields:
Translation:
Humans
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Proresolving protein Annexin A1: The role in type 2 diabetes mellitus and obesity. Biomed Pharmacother. 2018 Jul; 103:482-489.
Pietrani NT, Ferreira CN, Rodrigues KF, Perucci LO, Carneiro FS, Bosco AA, Oliveira MC, Pereira SS, Teixeira AL, Alvarez-Leite JI, Ferreira AV, Sousa LP, Gomes KB. PMID: 29677533.
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16 Fields:
Translation:
Humans
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Is there a link among thrombophilia factors and preeclampsia? J Thromb Thrombolysis. 2017 Nov; 44(4):516-518.
Rios DRA, Alpoim PN, Godoi LC, Mendes FS, Lwaleed B, Sousa LP, Perucci LO, Carvalho MG, Borges KBG, Dusse LMS. PMID: 28975478.
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5 Fields:
Translation:
Humans
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FVIIa-antithrombin levels in early and late preeclampsia. Clin Chim Acta. 2017 Nov; 474:67-69.
Dusse LMS, Godoi LC, Alpoim PN, Gomes KB, Sousa LP, Perucci LO, Lwaleed B, Carvalho MG. PMID: 28887028.
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3 Fields:
Translation:
Humans
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Annexin A1 and specialized proresolving lipid mediators: promoting resolution as a therapeutic strategy in human inflammatory diseases. Expert Opin Ther Targets. 2017 09; 21(9):879-896.
Perucci LO, Sugimoto MA, Gomes KB, Dusse LM, Teixeira MM, Sousa LP. PMID: 28786708.
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24 Fields:
Translation:
HumansAnimals
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Resolution of inflammation pathways in preeclampsia-a narrative review. Immunol Res. 2017 08; 65(4):774-789.
Perucci LO, Corrêa MD, Dusse LM, Gomes KB, Sousa LP. PMID: 28391374.
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24 Fields:
Translation:
HumansAnimals
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Annexin A1 Is Involved in the Resolution of Inflammatory Responses during Leishmania braziliensis Infection. J Immunol. 2017 04 15; 198(8):3227-3236.
Oliveira LG, Souza-Testasicca MC, Vago JP, Figueiredo AB, Canavaci AM, Perucci LO, Ferreira TP, Coelho EA, Gonçalves DU, Rocha MO, E Silva PM, Ferreira CN, Queiroz-Junior C, Sousa LP, Fernandes AP. PMID: 28289158.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Decreased plasma concentrations of brain-derived neurotrophic factor in preeclampsia. Clin Chim Acta. 2017 Jan; 464:142-147.
Perucci LO, Vieira ÉLM, Teixeira AL, Gomes KB, Dusse LM, Sousa LP. PMID: 27887959.
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8 Fields:
Translation:
HumansCells
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Increased Levels of sENG and sVCAM-1 and Decreased Levels of VEGF in Severe Preeclampsia. Am J Hypertens. 2016 11 01; 29(11):1307-1310.
Rios DRA, Alpoim PN, Godoi LC, Perucci LO, de Sousa LP, Gomes KB, Dusse LMS. PMID: 26476083.
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15 Fields:
Translation:
Humans
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Lipoxin A4 Is Increased in the Plasma of Preeclamptic Women. Am J Hypertens. 2016 10; 29(10):1179-85.
Perucci LO, Santos PC, Ribeiro LS, Souza DG, Gomes KB, Dusse LM, Sousa LP. PMID: 27179254.
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6 Fields:
Translation:
Humans
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Annexin A1 Is Increased in the Plasma of Preeclamptic Women. PLoS One. 2015; 10(9):e0138475.
Perucci LO, Carneiro FS, Ferreira CN, Sugimoto MA, Soriani FM, Martins GG, Lima KM, Guimarães FL, Teixeira AL, Dusse LM, Gomes KB, Sousa LP. PMID: 26398190; PMCID: PMC4580581.
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13 Fields:
Translation:
Humans
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The role and effects of glucocorticoid-induced leucine zipper in the context of inflammation resolution. J Immunol. 2015 May 15; 194(10):4940-50.
Vago JP, Tavares LP, Garcia CC, Lima KM, Perucci LO, Vieira ÉL, Nogueira CR, Soriani FM, Martins JO, Silva PM, Gomes KB, Pinho V, Bruscoli S, Riccardi C, Beaulieu E, Morand EF, Teixeira MM, Sousa LP. PMID: 25876761.
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PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
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Soluble endoglin, transforming growth factor-Beta 1 and soluble tumor necrosis factor alpha receptors in different clinical manifestations of preeclampsia. PLoS One. 2014; 9(5):e97632.
Perucci LO, Gomes KB, Freitas LG, Godoi LC, Alpoim PN, Pinheiro MB, Miranda AS, Teixeira AL, Dusse LM, Sousa LP. PMID: 24851923; PMCID: PMC4031102.
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PubMed Mentions:
30 Fields:
Translation:
Humans