Robert Parmer

Title(s)Recall Hcomp, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    A Novel Plasminogen Receptor Promotes Adipose Function and Metabolic Homeostasis
    NIH R01HL149511May 1, 2019 - Apr 30, 2023
    Role: Co-Principal Investigator
    Regulation of Renal Injury and Fibrosis by the Plasminogen Receptor, Plg-RKT
    NIH I01BX003933Apr 1, 2018 - Mar 31, 2022
    Role: Principal Investigator
    Cell Surface Plasminogen Activation and Hypertension
    NIH I01BX002026Apr 1, 2013 - Mar 31, 2017
    Role: Principal Investigator
    PROCESSING OF CHROMOGRANIN A BY THE FIBRINOLYTIC SYSTEM
    NIH R01HL050398Sep 1, 1994 - Jun 30, 2005
    Role: Principal Investigator
    AUTONOMIC AND RENAL PHENOTYPES IN BLACK PEDIGREES
    NIH R01HL050174Sep 30, 1992 - Sep 29, 1995
    Role: Principal Investigator
    CHROMOGRANIN
    NIH K11HL001416Jul 1, 1984 - Jun 30, 1990
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Plg-RKT Expression in Human Breast Cancer Tissues. Biomolecules. 2022 03 26; 12(4). Miles LA, Krajewski S, Baik N, Parmer RJ, Mueller BM. PMID: 35454092; PMCID: PMC9028288.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. The plasminogen receptor Plg-RKT regulates adipose function and metabolic homeostasis. J Thromb Haemost. 2022 03; 20(3):742-754. Samad F, Bai H, Baik N, Haider P, Zhang Y, Rega-Kaun G, Kaun C, Prager M, Wojta J, Bui Q, Chakrabarty S, Wang J, Parmer RJ, Miles LA. PMID: 34897983; PMCID: PMC8885904.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    3. Plasminogen Receptors and Fibrinolysis. Int J Mol Sci. 2021 Feb 08; 22(4). Miles LA, Ny L, Wilczynska M, Shen Y, Ny T, Parmer RJ. PMID: 33567773; PMCID: PMC7914795.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    4. Exposure of plasminogen and a novel plasminogen receptor, Plg-RKT, on activated human and murine platelets. Blood. 2021 01 14; 137(2):248-257. Whyte CS, Morrow GB, Baik N, Booth NA, Jalal MM, Parmer RJ, Miles LA, Mutch NJ. PMID: 32842150; PMCID: PMC7820873.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    5. The plasminogen receptor, Plg-RKT, plays a role in inflammation and fibrinolysis during cutaneous wound healing in mice. Cell Death Dis. 2020 12 12; 11(12):1054. Ny L, Parmer RJ, Shen Y, Holmberg S, Baik N, Bäckman A, Broden J, Wilczynska M, Ny T, Miles LA. PMID: 33311441; PMCID: PMC7733490.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    6. Functions of the plasminogen receptor Plg-RKT. J Thromb Haemost. 2020 10; 18(10):2468-2481. Miles LA, Vago JP, Sousa LP, Parmer RJ. PMID: 32662180; PMCID: PMC7722214.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    7. Neuroendocrine Targeting of Tissue Plasminogen Activator (t-PA). J Neurol Disord Stroke. 2020; 7(1). Parmer RJ, Gong Y, Yoo SH, Miles LA. PMID: 32549050; PMCID: PMC7297194.
      View in: PubMed   Mentions: 1  
    8. Plasminogen and the Plasminogen Receptor, Plg-RKT, Regulate Macrophage Phenotypic, and Functional Changes. Front Immunol. 2019; 10:1458. Vago JP, Sugimoto MA, Lima KM, Negreiros-Lima GL, Baik N, Teixeira MM, Perretti M, Parmer RJ, Miles LA, Sousa LP. PMID: 31316511; PMCID: PMC6611080.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    9. Differential expression of Plg-RKT and its effects on migration of proinflammatory monocyte and macrophage subsets. Blood. 2019 08 08; 134(6):561-567. Thaler B, Baik N, Hohensinner PJ, Baumgartner J, Panzenböck A, Stojkovic S, Demyanets S, Huk I, Rega-Kaun G, Kaun C, Prager M, Fischer MB, Huber K, Speidl WS, Parmer RJ, Miles LA, Wojta J. PMID: 31221672; PMCID: PMC6688429.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    10. tPA and anger management for macrophages. Blood. 2017 09 14; 130(11):1280-1281. Miles LA, Parmer RJ. PMID: 28912293; PMCID: PMC5600143.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. Astrocytes regulate the balance between plasminogen activation and plasmin clearance via cell-surface actin. Cell Discov. 2017; 3:17001. Briens A, Bardou I, Lebas H, Miles LA, Parmer RJ, Vivien D, Docagne F. PMID: 28417010; PMCID: PMC5318850.
      View in: PubMed   Mentions: 14  
    12. Angry macrophages patrol for fibrin. Blood. 2016 Mar 03; 127(9):1079-80. Miles LA, Parmer RJ. PMID: 26941388; PMCID: PMC4778160.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    13. Setting the table for macrophages. Blood. 2014 Jul 31; 124(5):665-6. Miles LA, Parmer RJ. PMID: 25082858; PMCID: PMC4118476.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    14. New insights into the role of Plg-RKT in macrophage recruitment. Int Rev Cell Mol Biol. 2014; 309:259-302. Miles LA, Lighvani S, Baik N, Parmer CM, Khaldoyanidi S, Mueller BM, Parmer RJ. PMID: 24529725; PMCID: PMC4060795.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    15. Plasminogen receptors: the first quarter century. Semin Thromb Hemost. 2013 Jun; 39(4):329-37. Miles LA, Parmer RJ. PMID: 23532575; PMCID: PMC3938387.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    16. Plasminogen receptors. J Biomed Biotechnol. 2012; 2012:130735. Miles LA, Plow EF, Waisman DM, Parmer RJ. PMID: 23226936; PMCID: PMC3511834.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    17. The plasminogen activation system and the regulation of catecholaminergic function. J Biomed Biotechnol. 2012; 2012:721657. Bai H, Nangia S, Parmer RJ. PMID: 23097598; PMCID: PMC3477892.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    18. The plasminogen receptor, Plg-R(KT), and macrophage function. J Biomed Biotechnol. 2012; 2012:250464. Miles LA, Lighvani S, Baik N, Andronicos NM, Chen EI, Parmer CM, Khaldoyanidi S, Diggs JE, Kiosses WB, Kamps MP, Yates JR, Parmer RJ. PMID: 23125524; PMCID: PMC3484331.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    19. Monoclonal antibodies against receptor-induced binding sites detect cell-bound plasminogen in blood. Blood. 2012 Jul 19; 120(3):678-81. Félez J, Jardí M, Fàbregas P, Parmer RJ, Miles LA. PMID: 22649107; PMCID: PMC3401219.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    20. Regulation of macrophage migration by a novel plasminogen receptor Plg-R KT. Blood. 2011 Nov 17; 118(20):5622-30. Lighvani S, Baik N, Diggs JE, Khaldoyanidi S, Parmer RJ, Miles LA. PMID: 21940822; PMCID: PMC3217361.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    21. The novel plasminogen receptor, plasminogen receptor(KT) (Plg-R(KT)), regulates catecholamine release. J Biol Chem. 2011 Sep 23; 286(38):33125-33. Bai H, Baik N, Kiosses WB, Krajewski S, Miles LA, Parmer RJ. PMID: 21795689; PMCID: PMC3190921.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    22. Monoclonal antibodies detect receptor-induced binding sites in Glu-plasminogen. Blood. 2011 Aug 11; 118(6):1653-62. Han J, Baik N, Kim KH, Yang JM, Han GW, Gong Y, Jardí M, Castellino FJ, Felez J, Parmer RJ, Miles LA. PMID: 21680799; PMCID: PMC3156051.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    23. The anti-fibrinolytic SERPIN, plasminogen activator inhibitor 1 (PAI-1), is targeted to and released from catecholamine storage vesicles. Blood. 2011 Jun 30; 117(26):7155-63. Jiang Q, Gingles NA, Olivier MA, Miles LA, Parmer RJ. PMID: 21596853; PMCID: PMC3143556.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    24. S100A10: a complex inflammatory role. Blood. 2010 Aug 19; 116(7):1022-4. Miles LA, Parmer RJ. PMID: 20724548.
      View in: PubMed   Mentions: 3     Fields:    
    25. PAI-1: cardiac friend or foe? Blood. 2010 Mar 11; 115(10):1862-3. Miles LA, Parmer RJ. PMID: 20223930.
      View in: PubMed   Mentions: 3     Fields:    
    26. Proteomics-based discovery of a novel, structurally unique, and developmentally regulated plasminogen receptor, Plg-RKT, a major regulator of cell surface plasminogen activation. Blood. 2010 Feb 18; 115(7):1319-30. Andronicos NM, Chen EI, Baik N, Bai H, Parmer CM, Kiosses WB, Kamps MP, Yates JR, Parmer RJ, Miles LA. PMID: 19897580; PMCID: PMC2826757.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    27. Plasminogen enhances neuritogenesis on laminin-1. J Neurosci. 2009 Oct 07; 29(40):12393-400. Gutiérrez-Fernández A, Gingles NA, Bai H, Castellino FJ, Parmer RJ, Miles LA. PMID: 19812315; PMCID: PMC2789650.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    28. Cell-surface actin binds plasminogen and modulates neurotransmitter release from catecholaminergic cells. J Neurosci. 2006 Dec 13; 26(50):13017-24. Miles LA, Andronicos NM, Baik N, Parmer RJ. PMID: 17167091; PMCID: PMC6674961.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    29. Genetic variation at the human alpha2B-adrenergic receptor locus: role in blood pressure variation and yohimbine response. Hypertension. 2005 Jun; 45(6):1207-13. Etzel JP, Rana BK, Wen G, Parmer RJ, Schork NJ, O'Connor DT, Insel PA. PMID: 15920038.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    30. Plasminogen receptors: the sine qua non of cell surface plasminogen activation. Front Biosci. 2005 May 01; 10:1754-62. Miles LA, Hawley SB, Baik N, Andronicos NM, Castellino FJ, Parmer RJ. PMID: 15769664.
      View in: PubMed   Mentions: 52     Fields:    Translation:Animals
    31. Human sympathetic activation by alpha2-adrenergic blockade with yohimbine: Bimodal, epistatic influence of cytochrome P450-mediated drug metabolism. Clin Pharmacol Ther. 2004 Aug; 76(2):139-53. Le Corre P, Parmer RJ, Kailasam MT, Kennedy BP, Skaar TP, Ho H, Leverge R, Smith DW, Ziegler MG, Insel PA, Schork NJ, Flockhart DA, O'connor DT. PMID: 15289791.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    32. Primary sequence characterization of catestatin intermediates and peptides defines proteolytic cleavage sites utilized for converting chromogranin a into active catestatin secreted from neuroendocrine chromaffin cells. Biochemistry. 2003 Jun 17; 42(23):6938-46. Lee JC, Taylor CV, Gaucher SP, Toneff T, Taupenot L, Yasothornsrikul S, Mahata SK, Sei C, Parmer RJ, Neveu JM, Lane WS, Gibson BW, O'Connor DT, Hook VY. PMID: 12795588.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    33. Diminished renal kallikrein responses to mineralocorticoid stimulation in African Americans: determinants of an intermediate phenotype for hypertension. Am J Hypertens. 2003 Apr; 16(4):281-9. Wong CM, O'Connor DT, Martinez JA, Kailasam MT, Parmer RJ. PMID: 12670744.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    34. Identification of a novel sorting determinant for the regulated pathway in the secretory protein chromogranin A. J Cell Sci. 2002 Dec 15; 115(Pt 24):4827-41. Taupenot L, Harper KL, Mahapatra NR, Parmer RJ, Mahata SK, O'Connor DT. PMID: 12432071.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    35. The local chromaffin cell plasminogen/plasmin system and the regulation of catecholamine secretion. Ann N Y Acad Sci. 2002 Oct; 971:445-9. Jiang Q, Yasothornsrikul S, Taupenot L, Miles LA, Parmer RJ. PMID: 12438162.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    36. Chromaffin cell plasminogen receptors. Ann N Y Acad Sci. 2002 Oct; 971:454-9. Miles LA, Hawley SB, Parmer RJ. PMID: 12438164.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    37. The catecholamine release-inhibitory "catestatin" region of chromogranin a: early decline in humans at genetic risk of hypertension. Ann N Y Acad Sci. 2002 Oct; 971:533-5. O'Connor DT, Kailasam MT, Kennedy BP, Ziegler MG, Yanaihara N, Parmer RJ. PMID: 12438176.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    38. Intracellular protein trafficking into catecholamine storage vesicles: novel chimeric photoproteins visualized by deconvolution fluorescence microscopy. Ann N Y Acad Sci. 2002 Oct; 971:262-5. Taupenot L, Harper KL, Mahapatra NR, Parmer RJ, O'Connor DT. PMID: 12438129.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    39. Catecholaminergic pathways, chromaffin cells, and human disease. Ann N Y Acad Sci. 2002 Oct; 971:497-505. Parmer RJ, Zinder O. PMID: 12438170.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    40. Localization of regulatory elements mediating constitutive and cytokine-stimulated plasminogen gene expression. J Biol Chem. 2002 Oct 11; 277(41):38579-88. Bannach FG, Gutierrez A, Fowler BJ, Bugge TH, Degen JL, Parmer RJ, Miles LA. PMID: 12149246.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    41. Early decline in the catecholamine release-inhibitory peptide catestatin in humans at genetic risk of hypertension. J Hypertens. 2002 Jul; 20(7):1335-45. O'Connor DT, Kailasam MT, Kennedy BP, Ziegler MG, Yanaihara N, Parmer RJ. PMID: 12131530.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCTClinical Trials
    42. Plasminogen has a broad extrahepatic distribution. Thromb Haemost. 2002 Mar; 87(3):493-501. Zhang L, Seiffert D, Fowler BJ, Jenkins GR, Thinnes TC, Loskutoff DJ, Parmer RJ, Miles LA. PMID: 11916082.
      View in: PubMed   Mentions: 43     Fields:    Translation:Animals
    43. Processing of chromogranin A by plasmin provides a novel mechanism for regulating catecholamine secretion. J Clin Invest. 2000 Oct; 106(7):907-15. Parmer RJ, Mahata M, Gong Y, Mahata SK, Jiang Q, O'Connor DT, Xi XP, Miles LA. PMID: 11018079; PMCID: PMC381423.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    44. Tissue plasminogen activator (t-PA) is targeted to the regulated secretory pathway. Catecholamine storage vesicles as a reservoir for the rapid release of t-PA. J Biol Chem. 1997 Jan 17; 272(3):1976-82. Parmer RJ, Mahata M, Mahata S, Sebald MT, O'Connor DT, Miles LA. PMID: 8999889.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
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