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Outcomes following radiation therapy for embryonal tumor with multilayered rosettes (ETMR): results from the Pediatric Proton/Photon Consortium Registry (PPCR). J Neurooncol. 2025 May 13.
Krisch JM, Ermoian RP, Indelicato DJ, Lee JY, Perentesis JP, Perkins SM, Laack NN, Chang JH, MacEwan IJ, Wolden SL, Wang D, Yock TI, Aridgides PD. PMID: 40358803.
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Acute Toxicities of Proton Craniospinal Irradiation in Pediatric Medulloblastoma: A Pediatric Proton/Photon Consortium Registry (PPCR) Study. Int J Part Ther. 2025 Jun; 16:100747.
Nguyen P, Indelicato DJ, Esterman A, Paulino AC, Ermoian RP, Laack NN, Perkins SM, Mangona V, Mihalcik S, Lee J, Hill-Kayser C, Kwok Y, Chang JH, Perentesis JP, MacEwan I, Le H, Yock TI. PMID: 40336980; PMCID: PMC12056773.
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A quantitative framework for patient-specific collision detection in proton therapy. J Appl Clin Med Phys. 2024 Apr; 25(4):e14247.
Northway SK, Vallejo BM, Liu L, Hansen EE, Tang S, Mah D, MacEwan IJ, Urbanic JJ, Chang C. PMID: 38131514; PMCID: PMC11005990.
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Humans
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Correction to: Radiotherapy for Atypical Teratoid/Rhabdoid Tumor (ATRT) on the Pediatric Proton/Photon Consortium Registry (PPCR). J Neurooncol. 2023 Aug; 164(1):269.
Roehrig A, Indelicato DJ, Paulino AC, Ermoian R, Hartsell W, Perentesis J, Hill-Kayser C, Lee JY, Laack NN, Mangona V, MacEwan I, Eaton BR, Gallotto S, Bajaj BVM, Aridgides PD, Yock TI. PMID: 37498475.
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Radiotherapy for Atypical Teratoid/Rhabdoid Tumor (ATRT) on the Pediatric Proton/Photon Consortium Registry (PPCR). J Neurooncol. 2023 Apr; 162(2):353-362.
Roehrig A, Indelicato DJ, Paulino AC, Ermoian R, Hartsell W, Perentesis J, Hill-Kayser C, Lee JY, Laack NN, Mangona V, MacEwan I, Eaton BR, Gallotto S, Bajaj BVM, Aridgides PD, Yock TI. PMID: 36951945.
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1 Fields:
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Humans
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Toward automatic beam angle selection for pencil-beam scanning proton liver treatments: A deep learning-based approach. Med Phys. 2022 Jul; 49(7):4293-4304.
Kaderka R, Liu KC, Liu L, VanderStraeten R, Liu TL, Lee KM, Tu YE, MacEwan I, Simpson D, Urbanic J, Chang C. PMID: 35488864.
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3 Fields:
Translation:
Humans
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Post-treatment neuroendocrine outcomes among pediatric brain tumor patients: Is there a difference between proton and photon therapy? Clin Transl Radiat Oncol. 2022 May; 34:37-41.
Yip AT, Yu JD, Huynh-Le MP, Salans M, Unnikrishnan S, Qian AS, Xu R, Kaner R, MacEwan I, Crawford JR, Hattangadi-Gluth JA. PMID: 35345865; PMCID: PMC8956840.
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1
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Volumetric de-escalation and improved acute toxicity with proton craniospinal irradiation using a vertebral body-sparing technique. Pediatr Blood Cancer. 2022 05; 69(5):e29489.
Chou B, Hopper A, Elster J, Crawford JR, McConnell K, Chang A, Mundt AJ, MacEwan I. PMID: 34866330.
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2 Fields:
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Humans
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Variation in Proton Craniospinal Irradiation Practice Patterns in the United States: A Pediatric Proton Consortium Registry (PPCR) Study. Int J Radiat Oncol Biol Phys. 2022 03 15; 112(4):901-912.
Connor M, Paulino AC, Ermoian RP, Hartsell WF, Indelicato DJ, Perkins S, Mangona V, DeNunzio N, Laack NN, Hill-Kayser C, Kwok Y, Chang JH, Yock T, MacEwan I. PMID: 34808253.
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5 Fields:
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Humans
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Practice Patterns of Pediatric Total Body Irradiation Techniques: A Children's Oncology Group Survey. Int J Radiat Oncol Biol Phys. 2021 12 01; 111(5):1155-1164.
Rassiah P, Esiashvili N, Olch AJ, Hua CH, Ulin K, Molineu A, Marcus K, Gopalakrishnan M, Pillai S, Kovalchuk N, Liu A, Niyazov G, Peñagarícano J, Cheung F, Olson AC, Wu CC, Malhotra HK, MacEwan IJ, Faught J, Breneman JC, Followill DS, FitzGerald TJ, Kalapurakal JA. PMID: 34352289; PMCID: PMC11977860.
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9 Fields:
Translation:
Humans
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Wilms Tumor (Nephroblastoma), Version 2.2021, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2021 08 01; 19(8):945-977.
Balis F, Green DM, Anderson C, Cook S, Dhillon J, Gow K, Hiniker S, Jasty-Rao R, Lin C, Lovvorn H, MacEwan I, Martinez-Agosto J, Mullen E, Murphy ES, Ranalli M, Rhee D, Rokitka D, Tracy EL, Vern-Gross T, Walsh MF, Walz A, Wickiser J, Zapala M, Berardi RA, Hughes M. PMID: 34416707.
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13 Fields:
Translation:
Humans
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Utility of Multi-institutional Pediatric Chart Rounds in the Age of Telemedicine. Int J Radiat Oncol Biol Phys. 2021 08 01; 110(5):1272-1273.
Feng CH, Braunstein SE, MacEwan I. PMID: 33775858.
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1 Fields:
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HumansPHPublic Health
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Improving the Pediatric Patient Experience During Radiation Therapy-A Children's Oncology Group Study. Int J Radiat Oncol Biol Phys. 2021 02 01; 109(2):505-514.
Holt DE, Hiniker SM, Kalapurakal JA, Breneman JC, Shiao JC, Boik N, Cooper BT, Dorn PL, Hall MD, Logie N, Lucas JT, MacEwan IJ, Olson AC, Palmer JD, Patel S, Pater LE, Surgener S, Tsang DS, Vogel JH, Wojcik A, Wu CC, Milgrom SA. PMID: 32931864; PMCID: PMC9092316.
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4 Fields:
Translation:
Humans
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An open invitation to join the Pediatric Proton/Photon Consortium Registry to standardize data collection in pediatric radiation oncology. Br J Radiol. 2020 Mar; 93(1107):20190673.
Lawell MP, Indelicato DJ, Paulino AC, Hartsell W, Laack NN, Ermoian RP, Perentesis JP, Vatner R, Perkins S, Mangona VS, Hill-Kayser CE, Wolden SL, Kwok Y, Chang JH, Wilkinson JB, MacEwan I, Chang AL, Eaton BR, Ladra MM, Gallotto SL, Weyman EA, Bajaj BVM, Baliga S, Yeap BY, Berrington de Gonzalez A, Yock TI. PMID: 31600082; PMCID: PMC7066966.
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13 Fields:
Translation:
Humans
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Effects of vertebral-body-sparing proton craniospinal irradiation on the spine of young pediatric patients with medulloblastoma. Adv Radiat Oncol. 2017 Apr-Jun; 2(2):220-227.
MacEwan I, Chou B, Moretz J, Loredo L, Bush D, Slater JD. PMID: 28740935; PMCID: PMC5514252.
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13
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Discovery of (1S,2R,3S,4S,5R,6R)-2-Amino-3-[(3,4-difluorophenyl)sulfanylmethyl]-4-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Hydrochloride (LY3020371·HCl): A Potent, Metabotropic Glutamate 2/3 Receptor Antagonist with Antidepressant-Like Activity. J Med Chem. 2016 12 22; 59(24):10974-10993.
Chappell MD, Li R, Smith SC, Dressman BA, Tromiczak EG, Tripp AE, Blanco MJ, Vetman T, Quimby SJ, Matt J, Britton TC, Fivush AM, Schkeryantz JM, Mayhugh D, Erickson JA, Bures MG, Jaramillo C, Carpintero M, Diego JE, Barberis M, Garcia-Cerrada S, Soriano JF, Antonysamy S, Atwell S, MacEwan I, Condon B, Sougias C, Wang J, Zhang A, Conners K, Groshong C, Wasserman SR, Koss JW, Witkin JM, Li X, Overshiner C, Wafford KA, Seidel W, Wang XS, Heinz BA, Swanson S, Catlow JT, Bedwell DW, Monn JA, Mitch CH, Ornstein PL. PMID: 28002967.
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7 Fields:
Translation:
HumansAnimalsCells
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Correction to The 2.5 Å Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD(+)) and an Indole (EX527 Analogue) Reveals a Novel Mechanism of Histone Deacetylase Inhibition. J Med Chem. 2016 Mar 10; 59(5):2267.
Zhao X, Allison D, Condon B, Zhang F, Gheyi T, Zhang A, Ashok S, Russell M, MacEwan I, Qian Y, Jamison JA, Luz JG. PMID: 26882000.
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1 Fields:
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Proton density water fraction as a biomarker of bone marrow cellularity: validation in ex vivo spine specimens. Magn Reson Imaging. 2014 Nov; 32(9):1097-101.
MacEwan IJ, Glembotski NE, D'Lima D, Bae W, Masuda K, Rashidi HH, Mell LK, Bydder M. PMID: 25240720.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Structural context of disease-associated mutations and putative mechanism of autoinhibition revealed by X-ray crystallographic analysis of the EZH2-SET domain. PLoS One. 2013; 8(12):e84147.
Antonysamy S, Condon B, Druzina Z, Bonanno JB, Gheyi T, Zhang F, MacEwan I, Zhang A, Ashok S, Rodgers L, Russell M, Gately Luz J. PMID: 24367637; PMCID: PMC3868555.
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PubMed Mentions:
42 Fields:
Translation:
HumansAnimalsCells
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Race and competing mortality in advanced head and neck cancer. Oral Oncol. 2014 Jan; 50(1):40-4.
Zakeri K, MacEwan I, Vazirnia A, Cohen EE, Spiotto MT, Haraf DJ, Vokes EE, Weichselbaum RR, Mell LK. PMID: 24134948.
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10 Fields:
Translation:
Humans
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The 2.5 Å crystal structure of the SIRT1 catalytic domain bound to nicotinamide adenine dinucleotide (NAD+) and an indole (EX527 analogue) reveals a novel mechanism of histone deacetylase inhibition. J Med Chem. 2013 Feb 14; 56(3):963-9.
Zhao X, Allison D, Condon B, Zhang F, Gheyi T, Zhang A, Ashok S, Russell M, MacEwan I, Qian Y, Jamison JA, Luz JG. PMID: 23311358.
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PubMed Mentions:
68 Fields:
Translation:
HumansCells