Edward Koellhoffer

Title(s)Resident Physician, Radiology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    University of Texas Health Sciences Center at Houston, Houston, TX06/2019Preliminary Internship (Internal Medicine)
    McGovern Medical School at UTHealth, Houston, TXMD05/2019Doctor of Medicine
    The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TXPhD05/2019Neuroscience
    Boston College, Chestnut Hill, MABS05/2009Biochemistry

    Collapse Research 
    Collapse Research Activities and Funding
    The Aging Microglia: the Role of Exh2 in Pro-Inflammatory Phenotype Polarization
    NIH F30NS095511Sep 1, 2016 - Jan 31, 2020
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. 3D bioprinting cowpea mosaic virus as an immunotherapy depot for ovarian cancer prevention in a preclinical mouse model. Mater Adv. 2024 Feb 19; 5(4):1480-1486. Zhao Z, Xiang Y, Koellhoffer EC, Shukla S, Fiering S, Chen S, Steinmetz NF. PMID: 38380337; PMCID: PMC10876074.
      View in: PubMed   Mentions:
    2. Inactivated Cowpea Mosaic Virus for In Situ Vaccination: Differential Efficacy of Formalin vs UV-Inactivated Formulations. Mol Pharm. 2023 01 02; 20(1):500-507. Jung E, Mao C, Bhatia M, Koellhoffer EC, Fiering SN, Steinmetz NF. PMID: 36399598; PMCID: PMC9812890.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCellsPHPublic Health
    3. Cowpea Mosaic Virus and Natural Killer Cell Agonism for In Situ Cancer Vaccination. Nano Lett. 2022 07 13; 22(13):5348-5356. Koellhoffer EC, Steinmetz NF. PMID: 35713326; PMCID: PMC9665426.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    4. Inactivated Cowpea Mosaic Virus in Combination with OX40 Agonist Primes Potent Antitumor Immunity in a Bilateral Melanoma Mouse Model. Mol Pharm. 2022 02 07; 19(2):592-601. Koellhoffer EC, Mao C, Beiss V, Wang L, Fiering SN, Boone CE, Steinmetz NF. PMID: 34978197; PMCID: PMC9207558.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    5. Integrating plant molecular farming and materials research for next-generation vaccines. Nat Rev Mater. 2022; 7(5):372-388. Chung YH, Church D, Koellhoffer EC, Osota E, Shukla S, Rybicki EP, Pokorski JK, Steinmetz NF. PMID: 34900343; PMCID: PMC8647509.
      View in: PubMed   Mentions: 32  
    6. Transforming growth factor-β promotes basement membrane fibrosis, alters perivascular cerebrospinal fluid distribution, and worsens neurological recovery in the aged brain after stroke. Geroscience. 2019 10; 41(5):543-559. Howe MD, Furr JW, Munshi Y, Roy-O'Reilly MA, Maniskas ME, Koellhoffer EC, d'Aigle J, Sansing LH, McCullough LD, Urayama A. PMID: 31721012; PMCID: PMC6885082.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    7. Inhibition of calcium/calmodulin-dependent protein kinase kinase (CaMKK) exacerbates impairment of endothelial cell and blood-brain barrier after stroke. Eur J Neurosci. 2019 01; 49(1):27-39. Sun P, Bu F, Min JW, Munshi Y, Howe MD, Liu L, Koellhoffer EC, Qi L, McCullough LD, Li J. PMID: 30422362; PMCID: PMC6590081.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    8. Myeloid-specific TAK1 deletion results in reduced brain monocyte infiltration and improved outcomes after stroke. J Neuroinflammation. 2018 May 17; 15(1):148. Chauhan A, Hudobenko J, Al Mamun A, Koellhoffer EC, Patrizz A, Ritzel RM, Ganesh BP, McCullough LD. PMID: 29776451; PMCID: PMC5960093.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    9. Ras-Related C3 Botulinum Toxin Substrate 1 Promotes Axonal Regeneration after Stroke in Mice. Transl Stroke Res. 2018 10; 9(5):506-514. Liu L, Yuan H, Yi Y, Koellhoffer EC, Munshi Y, Bu F, Zhang Y, Zhang Z, McCullough LD, Li J. PMID: 29476448; PMCID: PMC6598679.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    10. The G-quadruplex DNA stabilizing drug pyridostatin promotes DNA damage and downregulates transcription of Brca1 in neurons. Aging (Albany NY). 2017 09 12; 9(9):1957-1970. Moruno-Manchon JF, Koellhoffer EC, Gopakumar J, Hambarde S, Kim N, McCullough LD, Tsvetkov AS. PMID: 28904242; PMCID: PMC5636668.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    11. Multiparity improves outcomes after cerebral ischemia in female mice despite features of increased metabovascular risk. Proc Natl Acad Sci U S A. 2017 07 11; 114(28):E5673-E5682. Ritzel RM, Patel AR, Spychala M, Verma R, Crapser J, Koellhoffer EC, Schrecengost A, Jellison ER, Zhu L, Venna VR, McCullough LD. PMID: 28645895; PMCID: PMC5514696.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    12. Old Maids: Aging and Its Impact on Microglia Function. Int J Mol Sci. 2017 Apr 05; 18(4). Koellhoffer EC, McCullough LD, Ritzel RM. PMID: 28379162; PMCID: PMC5412353.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansAnimalsCells
    13. Ischemic stroke induces gut permeability and enhances bacterial translocation leading to sepsis in aged mice. Aging (Albany NY). 2016 05; 8(5):1049-63. Crapser J, Ritzel R, Verma R, Venna VR, Liu F, Chauhan A, Koellhoffer E, Patel A, Ricker A, Maas K, Graf J, McCullough LD. PMID: 27115295; PMCID: PMC4931853.
      View in: PubMed   Mentions: 74     Fields:    Translation:Animals
    14. Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters. Proc Natl Acad Sci U S A. 2013 Jun 18; 110(25):10165-70. Tolstorukov MY, Sansam CG, Lu P, Koellhoffer EC, Helming KC, Alver BH, Tillman EJ, Evans JA, Wilson BG, Park PJ, Roberts CW. PMID: 23723349; PMCID: PMC3690861.
      View in: PubMed   Mentions: 107     Fields:    Translation:AnimalsCells
    15. The effects of estrogen in ischemic stroke. Transl Stroke Res. 2013 Aug; 4(4):390-401. Koellhoffer EC, McCullough LD. PMID: 24323337; PMCID: PMC4275797.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    16. Epigenetic inactivation of the tumor suppressor BIN1 drives proliferation of SNF5-deficient tumors. Cell Cycle. 2012 May 15; 11(10):1956-65. McKenna ES, Tamayo P, Cho YJ, Tillman EJ, Mora-Blanco EL, Sansam CG, Koellhoffer EC, Pomeroy SL, Roberts CW. PMID: 22544318; PMCID: PMC3359122.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    17. Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation. Cancer Cell. 2010 Oct 19; 18(4):316-28. Wilson BG, Wang X, Shen X, McKenna ES, Lemieux ME, Cho YJ, Koellhoffer EC, Pomeroy SL, Orkin SH, Roberts CW. PMID: 20951942; PMCID: PMC2957473.
      View in: PubMed   Mentions: 331     Fields:    Translation:HumansAnimalsCells
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