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Derek Brown

Title(s)Clinical Professor, Radiation Medicine and Applied Science
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Integration of Germline and Somatic Variation Improves Chronic Lymphocytic Leukemia Risk Stratification. Cancer Res. 2025 Jul 15; 85(14):2743-2752. Hubbard AK, Brown DW, Liu J, Chan IC, Zhou W, Genovese G, DePaulis A, Srinivasan S, Lin SH, Blechter B, Buller ID, Zeng Q, Cao Y, Huang WY, Freedman ND, Zhang H, Dutta D, Chanock SJ, Bolton KL, Machiela MJ. PMID: 40305105; PMCID: PMC12263322.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Fragmentomic-based algorithm to computationally predict tumor-somatic, germline, and clonal hematopoiesis variant origin in liquid biopsy. J Liq Biopsy. 2025 Sep; 9:100311. Brown DW, Sun D, Fine AD, He S, McDevitt M, Pontbriand K, Polisecki E, Kou A, Li M, Zhang S, Kuang Z, Fabrizio D, Madison RW, He J, Assaf ZJ, Powles T, Sweeney C, Gandara D, Antonarakis ES, Albacker LA, Aiyer A, Yilmazel B, Decker BJ, Hughes JD, Tukachinsky H, Xu C. PMID: 40704056; PMCID: PMC12284786.
      View in: PubMed   Mentions:
    3. Author Correction: Genetic drivers and cellular selection of female mosaic X chromosome loss. Nature. 2024 Dec; 636(8043):E7. Liu A, Genovese G, Zhao Y, Pirinen M, Zekavat SM, Kentistou KA, Yang Z, Yu K, Vlasschaert C, Liu X, Brown DW, Hudjashov G, Gorman BR, Dennis J, Zhou W, Momozawa Y, Pyarajan S, Tuzov V, Pajuste FD, Aavikko M, Sipilä TP, Ghazal A, Huang WY, Freedman ND, Song L, Gardner EJ, FinnGen, Estonian Biobank Research Team, Breast Cancer Association Consortium, Million Veteran Program, Sankaran VG, Palotie A, Ollila HM, Tukiainen T, Chanock SJ, Mägi R, Natarajan P, Daly MJ, Bick A, McCarroll SA, Terao C, Loh PR, Ganna A, Perry JRB, Machiela MJ. PMID: 39627447.
      View in: PubMed   Mentions:    Fields:    
    4. Genetic drivers and cellular selection of female mosaic X chromosome loss. Nature. 2024 Jul; 631(8019):134-141. Liu A, Genovese G, Zhao Y, Pirinen M, Zekavat SM, Kentistou KA, Yang Z, Yu K, Vlasschaert C, Liu X, Brown DW, Hudjashov G, Gorman BR, Dennis J, Zhou W, Momozawa Y, Pyarajan S, Tuzov V, Pajuste FD, Aavikko M, Sipilä TP, Ghazal A, Huang WY, Freedman ND, Song L, Gardner EJ, FinnGen, Estonian Biobank Research Team, Breast Cancer Association Consortium, Million Veteran Program, Sankaran VG, Palotie A, Ollila HM, Tukiainen T, Chanock SJ, Mägi R, Natarajan P, Daly MJ, Bick A, McCarroll SA, Terao C, Loh PR, Ganna A, Perry JRB, Machiela MJ. PMID: 38867047.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    5. Measurement of ctDNA Tumor Fraction Identifies Informative Negative Liquid Biopsy Results and Informs Value of Tissue Confirmation. Clin Cancer Res. 2024 Jun 03; 30(11):2452-2460. Rolfo CD, Madison RW, Pasquina LW, Brown DW, Huang Y, Hughes JD, Graf RP, Oxnard GR, Husain H. PMID: 38526394; PMCID: PMC11145175.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    6. JAK2 V617F mutation and associated chromosomal alterations in primary and secondary myelofibrosis and post-HCT outcomes. Blood Adv. 2023 12 26; 7(24):7506-7515. Rafati M, Brown DW, Zhou W, Jones K, Luo W, St Martin A, Wang Y, He M, Spellman SR, Wang T, Deeg HJ, Gupta V, Lee SJ, Bolon YT, Chanock SJ, Machiela MJ, Saber W, Gadalla SM. PMID: 38011490; PMCID: PMC10758737.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Shared and distinct genetic etiologies for different types of clonal hematopoiesis. Nat Commun. 2023 09 08; 14(1):5536. Brown DW, Cato LD, Zhao Y, Nandakumar SK, Bao EL, Gardner EJ, Hubbard AK, DePaulis A, Rehling T, Song L, Yu K, Chanock SJ, Perry JRB, Sankaran VG, Machiela MJ. PMID: 37684235; PMCID: PMC10491829.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    8. Mosaic chromosomal alterations detected in men living with HIV and the relationship to non-Hodgkin lymphoma. AIDS. 2023 07 01; 37(8):1307-1313. Lin SH, Khan SM, Zhou W, Brown DW, Vergara C, Wolinsky SM, Martínez-Maza O, Margolick JB, Martinson JJ, Hussain SK, Engels EA, Machiela MJ. PMID: 36927626; PMCID: PMC10500031.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    9. Targeted long-read sequencing of the Ewing sarcoma 6p25.1 susceptibility locus identifies germline-somatic interactions with EWSR1-FLI1 binding. Am J Hum Genet. 2023 03 02; 110(3):427-441. Lee OW, Rodrigues C, Lin SH, Luo W, Jones K, Brown DW, Zhou W, Karlins E, Khan SM, Baulande S, Raynal V, Surdez D, Reynaud S, Rubio RA, Zaidi S, Grossetête S, Ballet S, Lapouble E, Laurence V, Pierron G, Gaspar N, Corradini N, Marec-Bérard P, Rothman N, Dagnall CL, Burdett L, Manning M, Wyatt K, Yeager M, Chari R, Leisenring WM, Kulozik AE, Kriebel J, Meitinger T, Strauch K, Kirchner T, Dirksen U, Mirabello L, Tucker MA, Tirode F, Armstrong GT, Bhatia S, Robison LL, Yasui Y, Romero-Pérez L, Hartmann W, Metzler M, Diver WR, Lori A, Freedman ND, Hoover RN, Morton LM, Chanock SJ, Grünewald TGP, Delattre O, Machiela MJ. PMID: 36787739; PMCID: PMC10027473.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    10. Population analyses of mosaic X chromosome loss identify genetic drivers and widespread signatures of cellular selection. medRxiv. 2023 Jan 31. Liu A, Genovese G, Zhao Y, Pirinen M, Zekavat MM, Kentistou K, Yang Z, Yu K, Vlasschaert C, Liu X, Brown DW, Hudjashov G, Gorman B, Dennis J, Zhou W, Momozawa Y, Pyarajan S, Tuzov V, Pajuste FD, Aavikko M, Sipilä TP, Ghazal A, Huang WY, Freedman N, Song L, Gardner EJ, Sankaran VG, Palotie A, Ollila HM, Tukiainen T, Chanock SJ, Mägi R, Natarajan P, Daly MJ, Bick A, McCarroll SA, Terao C, Loh PR, Ganna A, Perry JRB, Machiela MJ. PMID: 36778285; PMCID: PMC9915812.
      View in: PubMed   Mentions:
    11. Lower Extremity Musculoskeletal Injuries After Concussion in Collegiate Student-Athletes. Am J Sports Med. 2023 02; 51(2):511-519. Buckley TA, Chandran A, Mauntel TC, Kerr ZY, Brown DW, Boltz AJ, Herman DC, Hall EE, Lynall RC. PMID: 36255302.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    12. Examining the Effect of Direct Patient Care for Medical Physicists: A Randomized Prospective Phase III Trial. Int J Radiat Oncol Biol Phys. 2023 01 01; 115(1):224-232. Atwood TF, Brown DW, Murphy JD, Moore KL, Juang T, Azuara A, Mayadev JS, Rose BS, Sandhu AP, Mundt AJ, Pawlicki T. PMID: 36289039.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    13. Hazardous Attitudes: Physician Decision Making in Radiation Oncology. Adv Radiat Oncol. 2022 Nov-Dec; 7(6):101033. Saeed NA, Blakaj A, Kelly JR, Decker RH, Ford EC, Brown DW, Dosoretz AP, Evans SB. PMID: 36177486; PMCID: PMC9513093.
      View in: PubMed   Mentions: 1  
    14. Mitigating Bias in Recruitment: Attracting a Diverse, Dynamic Workforce to Sustain the Future of Radiation Oncology. Adv Radiat Oncol. 2022 Nov-Dec; 7(6):100977. Mokhtech M, Jagsi R, Vega RM, Brown DW, Golden DW, Juang T, Mattes MD, Pinnix CC, Evans SB. PMID: 36060636; PMCID: PMC9436705.
      View in: PubMed   Mentions:
    15. Patient Communication for Medical Physicists. J Am Coll Radiol. 2021 12; 18(12):1601-1604. Atwood TF, Brown DW, Pasciak AS, Samei E, Mahesh M, Pawlicki T. PMID: 34762832.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Comparative study of survival among small cell lung cancer patients in the U.S. military health system and those in the surveillance, epidemiology, and end results (SEER) program. Ann Epidemiol. 2021 12; 64:132-139. Lin J, Kamamia C, Brown DW, Shao S, McGlynn KA, Nations JA, Carter CA, Shriver CD, Zhu K. PMID: 34547444.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection. Nat Med. 2021 06; 27(6):1012-1024. Zekavat SM, Lin SH, Bick AG, Liu A, Paruchuri K, Wang C, Uddin MM, Ye Y, Yu Z, Liu X, Kamatani Y, Bhattacharya R, Pirruccello JP, Pampana A, Loh PR, Kohli P, McCarroll SA, Kiryluk K, Neale B, Ionita-Laza I, Engels EA, Brown DW, Smoller JW, Green R, Karlson EW, Lebo M, Ellinor PT, Weiss ST, Daly MJ, Biobank Japan Project, FinnGen Consortium, Terao C, Zhao H, Ebert BL, Reilly MP, Ganna A, Machiela MJ, Genovese G, Natarajan P. PMID: 34099924; PMCID: PMC8245201.
      View in: PubMed   Mentions: 105     Fields:    Translation:Humans
    18. Estimating local arterial stiffness using mixed-effects model-based residuals: a novel approach. Hypertens Res. 2021 06; 44(6):727-729. Chandran A, Brown DW, Zieff GH, Kerr ZY, Credeur D, Stoner L. PMID: 33510450.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Comparative Trends in the Distribution of Lung Cancer Stage at Diagnosis in the Department of Defense Cancer Registry and the Surveillance, Epidemiology, and End Results data, 1989-2012. Mil Med. 2020 12 30; 185(11-12):e2044-e2048. Nations JA, Brown DW, Shao S, Shriver CD, Zhu K. PMID: 32857164.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    20. A machine learning compatible method for ordinal propensity score stratification and matching. Stat Med. 2021 03 15; 40(6):1383-1399. Greene TJ, DeSantis SM, Brown DW, Wilkinson AV, Swartz MD. PMID: 33352615; PMCID: PMC8919399.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. Propensity score stratification methods for continuous treatments. Stat Med. 2021 02 28; 40(5):1189-1203. Brown DW, Greene TJ, Swartz MD, Wilkinson AV, DeSantis SM. PMID: 33305367; PMCID: PMC8629138.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    22. Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer. medRxiv. 2020 Nov 16. Zekavat SM, Lin SH, Bick AG, Liu A, Paruchuri K, Uddin MM, Ye Y, Yu Z, Liu X, Kamatani Y, Pirruccello JP, Pampana A, Loh PR, Kohli P, McCarroll SA, Neale B, Engels EA, Brown DW, Smoller JW, Green R, Karlson EW, Lebo M, Ellinor PT, Weiss ST, Daly MJ, Biobank Japan Project, FinnGen Consortium, Terao C, Zhao H, Ebert BL, COVID-19 Host Genetics Initiative, Ganna A, Machiela MJ, Genovese G, Natarajan P. PMID: 33236019; PMCID: PMC7685330.
      View in: PubMed   Mentions: 3  
    23. Genetically predicted telomere length is associated with clonal somatic copy number alterations in peripheral leukocytes. PLoS Genet. 2020 10; 16(10):e1009078. Brown DW, Lin SH, Loh PR, Chanock SJ, Savage SA, Machiela MJ. PMID: 33090998; PMCID: PMC7608979.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    24. Consolidation of Cancer Registry and Administrative Claims Data on Cancer Diagnosis and Treatment in the US Military Health System. JCO Clin Cancer Inform. 2020 10; 4:906-917. Eaglehouse YL, Park AB, Georg MW, Brown DW, Lin J, Shao S, Bytnar JA, Shriver CD, Zhu K. PMID: 33074744; PMCID: PMC7608597.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    25. ACR-ASTRO Practice Parameter for Communication: Radiation Oncology. Am J Clin Oncol. 2020 08; 43(8):553-558. Schechter NR, Brown DW, Bovi JA, Dominello MM, Liu AK, Mattes MD, Michalski JM, Shih HA, Strom E, Wilkinson JB, Rosenthal SA, Hartford A. PMID: 32520791.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    26. Evaluation of a Patient Communication Skills Training Program for Medical Physicists. Int J Radiat Oncol Biol Phys. 2020 12 01; 108(5):1284-1291. Brown DW, Atwood TF, Juang T, Moore KL, MacAulay R, Bazzo D, Murphy JD, Mundt AJ, Pawlicki T. PMID: 32711038.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    27. A review of patient questions from physicist-patient consults. J Appl Clin Med Phys. 2020 Aug; 21(8):305-308. Atwood TF, Brown DW, Juang T, Moore KL, McConnell KA, Steers JM, Murphy JD, Mundt AJ, Pawlicki T. PMID: 32519450; PMCID: PMC7484844.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    28. A novel approach for propensity score matching and stratification for multiple treatments: Application to an electronic health record-derived study. Stat Med. 2020 07 30; 39(17):2308-2323. Brown DW, DeSantis SM, Greene TJ, Maroufy V, Yaseen A, Wu H, Williams G, Swartz MD. PMID: 32297677; PMCID: PMC7334100.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    29. Global differences in the prevalence of the CpG island methylator phenotype of colorectal cancer. BMC Cancer. 2019 Oct 17; 19(1):964. Advani SM, Advani PS, Brown DW, DeSantis SM, Korphaisarn K, VonVille HM, Bressler J, Lopez DS, Davis JS, Daniel CR, Sarshekeh AM, Braithwaite D, Swartz MD, Kopetz S. PMID: 31623592; PMCID: PMC6796359.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    30. Sensitivity of the Mount Fuji Sign After Evacuation of Chronic Subdural Hematoma in Nonagenarians. J Comput Assist Tomogr. 2019 Sep/Oct; 43(5):686-689. Moscovici S, Halevy D, Mizrahi CJ, Goldberg SN, Brown DW, Ben-David E. PMID: 31356520.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    31. Error Types and Associations of Clinically Significant Events Within Food and Drug Administration Recalls of Linear Accelerators and Related Products. Pract Radiat Oncol. 2020 Jan - Feb; 10(1):e8-e15. Jairam V, Lincoln HM, Brown DW, Park HS, Evans SB. PMID: 31408733.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    32. A program to train medical physicists for direct patient care responsibilities. J Appl Clin Med Phys. 2018 Nov; 19(6):332-335. Brown DW, Atwood TF, Moore KL, MacAulay R, Murphy JD, Mundt AJ, Pawlicki T. PMID: 30328675; PMCID: PMC6236817.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    33. Establishing a New Clinical Role for Medical Physicists: A Prospective Phase II Trial. Int J Radiat Oncol Biol Phys. 2018 11 01; 102(3):635-641. Atwood TF, Brown DW, Murphy JD, Moore KL, Mundt AJ, Pawlicki T. PMID: 30244881.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    34. A ring-based compensator IMRT system optimized for low- and middle-income countries: Design and treatment planning study. Med Phys. 2018 Jul; 45(7):3275-3286. Van Schelt J, Smith DL, Fong N, Toomeh D, Sponseller PA, Brown DW, Macomber MW, Mayr NA, Patel S, Shulman A, Subrahmanyam GV, Govindarajan KN, Ford EC. PMID: 29777595; PMCID: PMC8522994.
      View in: PubMed   Mentions: 7     Fields:    
    35. Care for Patients, Not for Charts: A Future for Clinical Medical Physics. Int J Radiat Oncol Biol Phys. 2018 01 01; 100(1):21-22. Atwood TF, Brown DW, Murphy JD, Moore KL, Mundt AJ, Pawlicki T. PMID: 29254774.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    36. A consensus-based, process commissioning template for high-dose-rate gynecologic treatments. Brachytherapy. 2016 Sep-Oct; 15(5):570-7. Brown DW, Damato AL, Sutlief S, Morcovescu S, Park SJ, Reiff J, Shih A, Scanderbeg DJ. PMID: 27364873.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    37. Application of systems and control theory-based hazard analysis to radiation oncology. Med Phys. 2016 Mar; 43(3):1514-30. Pawlicki T, Samost A, Brown DW, Manger RP, Kim GY, Leveson NG. PMID: 26936735.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    38. The Case for Elective International Residency Rotations. Int J Radiat Oncol Biol Phys. 2015 Dec 01; 93(5):963-4. Brown DW, Einck J, Pawlicki T, Mundt AJ. PMID: 26581134.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    39. A framework for the implementation of new radiation therapy technologies and treatment techniques in low-income countries. Phys Med. 2014 Nov; 30(7):791-8. Brown DW, Shulman A, Hudson A, Smith W, Fisher B, Hollon J, Pipman Y, Van Dyk J, Einck J. PMID: 25096162.
      View in: PubMed   Mentions: 5     Fields:    
    40. Two-dimensional in vivo dose verification using portal imaging and correlation ratios. J Appl Clin Med Phys. 2014 Jul 08; 15(4):4752. Peca S, Brown DW. PMID: 25207402; PMCID: PMC5875516.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    41. Implementation of a high-dose-rate brachytherapy program for carcinoma of the cervix in Senegal: a pragmatic model for the developing world. Int J Radiat Oncol Biol Phys. 2014 Jul 01; 89(3):462-7. Einck JP, Hudson A, Shulman AC, Yashar CM, Dieng MM, Diagne M, Gueye L, Gningue F, Gaye PM, Fisher BJ, Mundt AJ, Brown DW. PMID: 24929155.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    42. Cobalt, linac, or other: what is the best solution for radiation therapy in developing countries? Int J Radiat Oncol Biol Phys. 2014 Jul 01; 89(3):476-80. Page BR, Hudson AD, Brown DW, Shulman AC, Abdel-Wahab M, Fisher BJ, Patel S. PMID: 24929157.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansPHPublic Health
    43. Aperture modulated, translating bed total body irradiation. Med Phys. 2011 Feb; 38(2):932-41. Hussain A, Villarreal-Barajas JE, Dunscombe P, Brown DW. PMID: 21452729.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
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