Darrell Fanestil

Title(s)Emeritus Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Hypertension Training Grant
    NIH T32HL007261Jul 1, 1996 - Aug 31, 2017
    Role: Co-Principal Investigator
    RAPID REGULATION OF THIAZIDE ACTION
    NIH R01DK040950Apr 1, 1989 - Mar 31, 1992
    Role: Principal Investigator
    RENAL BENZODIAZEPINE LIGANDS AND RECEPTORS
    NIH R01DK032579Apr 1, 1984 - Nov 30, 1987
    Role: Principal Investigator
    RENAL BENZODIAZEPINE LIGANDS AND RECEPTORS
    NIH R01AM032579Apr 1, 1984 - Mar 31, 1987
    Role: Principal Investigator
    PHOSPHATE TRANSPORT PROTEINS IN KIDNEY BRUSH BORDERS
    NIH R01AM032168Aug 1, 1983 - Mar 31, 1987
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dietary magnesium, not calcium, regulates renal thiazide receptor. J Am Soc Nephrol. 1999 Mar; 10(3):458-63. Fanestil DD, Hyde RH, Blakely P, Vaughn DA. PMID: 10073595.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    2. Genetic control of renal thiazide receptor response to dietary NaCl and hypertension. Am J Physiol. 1999 03; 276(3):R901-4. Fanestil DD, Vaughn DA, Hyde RH, Blakely P. PMID: 10070153.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    3. Dietary NaCl and KCl do not regulate renal density of the thiazide diuretic receptor. Am J Physiol. 1997 10; 273(4):R1241-5. Fanestil DD, Vaughn DA, Blakely P. PMID: 9362286.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    4. Metabolic acid-base influences on renal thiazide receptor density. Am J Physiol. 1997 Jun; 272(6 Pt 2):R2004-8. Fanestil DD, Vaughn DA, Blakely P. PMID: 9227621.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    5. Thiazide diuretics normalize urinary calcium in spontaneously hypertensive male rats. Kidney Int. 1997 Apr; 51(4):1018-21. Fanestil DD, Vaughn DA, Ma L, Hyde RH, Printz MP. PMID: 9083265.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    6. Amylin, calcitonin gene-related peptide, and adrenomedullin: effects on thiazide receptor and calcium. Am J Physiol. 1997 Mar; 272(3 Pt 2):F410-5. Blakely P, Vaughn DA, Fanestil DD. PMID: 9087686.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    7. Effects of calcium-modulating hormones on thiazide receptor density. J Am Soc Nephrol. 1996 Jul; 7(7):1052-7. Blakely P, Vaughn DA, Fanestil DD. PMID: 8829121.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    8. Adrenocortical steroids increase renal thiazide diuretic receptor density and response. J Am Soc Nephrol. 1994 Dec; 5(6):1361-8. Chen Z, Vaughn DA, Blakely P, Fanestil DD. PMID: 7894003.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    9. Influence of gender on renal thiazide diuretic receptor density and response. J Am Soc Nephrol. 1994 Oct; 5(4):1112-9. Chen Z, Vaughn DA, Fanestil DD. PMID: 7849251.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    10. Steroid regulation of thiazide-sensitive transport. Semin Nephrol. 1992 Jan; 12(1):18-23. Fanestil DD. PMID: 1549768.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    11. Licorice, computer-based analyses of dehydrogenase sequences, and the regulation of steroid and prostaglandin action. Mol Cell Endocrinol. 1991 Jun; 78(1-2):C99-102. Baker ME, Fanestil DD. PMID: 1834493.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    12. Inhibition of binding of [3H]metolazone to rat kidney membrane by stilbene disulfonates. Biochem Pharmacol. 1991 Jun 01; 41(11):1745-50. Luo H, Fanestil DD. PMID: 2043163.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    13. Effects of diuretic treatment and of dietary sodium on renal binding of 3H-metolazone. J Am Soc Nephrol. 1990 Jul; 1(1):91-8. Chen ZF, Vaughn DA, Beaumont K, Fanestil DD. PMID: 1966553.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    14. Solubilization of thiazide diuretic receptors from rat kidney membranes. Biochim Biophys Acta. 1990 Apr 09; 1052(1):119-22. Luo H, Beaumont K, Vaughn DA, Fanestil DD. PMID: 2322588.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    15. Effect of ions on binding of the thiazide-type diuretic metolazone to kidney membrane. Am J Physiol. 1990 Apr; 258(4 Pt 2):F908-15. Tran JM, Farrell MA, Fanestil DD. PMID: 2330985.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    16. Thiazide diuretic receptors in spontaneously hypertensive rats and 2-kidney 1-clip hypertensive rats. Clin Exp Hypertens A. 1990; 12(2):215-26. Beaumont K, Vaughn DA, Casto R, Printz MP, Fanestil DD. PMID: 2347095.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    17. Reversible downregulation of thiazide diuretic receptors by acute renal ischemia. Am J Physiol. 1989 Feb; 256(2 Pt 2):F329-34. Beaumont K, Vaughn DA, Maciejewski AR, Fanestil DD. PMID: 2916665.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    18. Mechanism of action of aldosterone blockers. Semin Nephrol. 1988 Sep; 8(3):249-63. Fanestil DD. PMID: 2849183.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    19. Thiazide diuretic drug receptors in rat kidney: identification with [3H]metolazone. Proc Natl Acad Sci U S A. 1988 Apr; 85(7):2311-4. Beaumont K, Vaughn DA, Fanestil DD. PMID: 3353380.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    20. Photoaffinity labeling of peripheral-type benzodiazepine receptors in rat kidney mitochondria with [3H]PK 14105. Eur J Pharmacol. 1988 Mar 29; 148(2):187-93. Skowronski R, Fanestil DD, Beaumont K. PMID: 2837399.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    21. Interactions of lipids with peripheral-type benzodiazepine receptors. Biochem Pharmacol. 1988 Mar 15; 37(6):1009-14. Beaumont K, Skowronski R, Vaughn DA, Fanestil DD. PMID: 2833268.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    22. Binding of calcium to the proteolipid phosphorin. Miner Electrolyte Metab. 1988; 14(2-3):135-41. Kessler RJ, Vaughn DA, Fanestil DD. PMID: 2454386.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    23. Selective pharmacological modulation of renal peripheral-type benzodiazepine binding by treatment with diuretic drugs. Life Sci. 1988; 42(4):367-73. Lukeman DS, Vaughn DA, Fanestil DD. PMID: 2828789.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    24. Effect of adrenocorticoid receptors on potassium and sodium flux in rat C6 glioma cells. J Steroid Biochem. 1987 Dec; 28(6):593-8. Beaumont K, Vaughn DA, Fanestil DD. PMID: 2826917.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    25. Modification of the peripheral-type benzodiazepine receptor by arachidonate, diethylpyrocarbonate and thiol reagents. Eur J Pharmacol. 1987 Nov 17; 143(3):305-14. Skowronski R, Beaumont K, Fanestil DD. PMID: 2826190.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    26. Artifactual phosphate binding due to impurities in [32P]orthophosphate. Anal Biochem. 1986 Oct; 158(1):117-8. Kessler RJ, Vaughn DA, Fanestil DD. PMID: 3026200.
      View in: PubMed   Mentions:    Fields:    
    27. Reconstitution of the partially purified renal phosphate (Pi) transporter. Biochem J. 1986 Apr 01; 235(1):189-97. Schäli C, Vaughn DA, Fanestil DD. PMID: 3741379.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    28. Phosphorin, a phosphate-binding hydrophobic protein isolated from renal brush border membranes. Adv Exp Med Biol. 1986; 208:83-92. Kessler RJ, Vaughn DA, Schäli C, Fanestil DD. PMID: 3565163.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    29. Autoradiographic localization of benzodiazepine receptors in the rat kidney. Am J Physiol. 1984 Nov; 247(5 Pt 2):F718-24. Beaumont K, Healy DP, Fanestil DD. PMID: 6093586.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    30. Enzymatic removal of alkaline phosphatase from renal brush-border membranes. Effect on phosphate transport and on phosphate binding. Biochim Biophys Acta. 1984 Jan 25; 769(2):277-83. Schäli C, Vaughn DA, Fanestil DD. PMID: 6696885.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    31. Mineralo- and glucocorticoid effects on renal excretion of electrolytes. Pflugers Arch. 1983 Oct; 399(2):93-101. Campen TJ, Vaughn DA, Fanestil DD. PMID: 6647008.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    32. Phosphate-binding proteolipid from brush border. J Biol Chem. 1982 Dec 10; 257(23):14311-7. Kessler RJ, Vaughn DA, Fanestil DD. PMID: 7142211.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    33. Competitive inhibition of dexamethasone binding to the glucocorticoid receptor in HTC cells by tryptophan methyl ester. J Steroid Biochem. 1980 Aug; 13(8):993-5. Baker ME, Vaughn DA, Fanestil DD. PMID: 7464144.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    34. Inhibition of short-circuit current by triaminopyrimidine in isolated toad urinary bladder. Am J Physiol. 1979 May; 236(5):C221-4. Fanestil DD, Vaughn DA. PMID: 109013.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    35. Specific binding of deoxycorticosterone by canine kidney cells in culture. J Steroid Biochem. 1978 Jan; 9(1):17-21. Ludens JH, Vaughn DA, Mawe RC, Fanestil DD. PMID: 564426.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    36. Inhibition by protease inhibitors of binding of adrenal and sex steroid hormones. J Supramol Struct. 1978; 9(3):421-6. Baker ME, Vaughn DA, Fanestil DD. PMID: 85807.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    37. Stimulation of urinary acidification by aldosterone and inhibitors of RNA and protein synthesis. J Membr Biol. 1978; 40 Spec No:199-211. Ludens JH, Vaughn DA, Fanestil DD. PMID: 83364.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    38. Induction of RNA and protein synthesis in the action of aldosterone in the rat. Am J Physiol. 1967 Oct; 213(4):954-62. Fimognari GM, Fanestil DD, Edelman IS. PMID: 6051194.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
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