Brian Daniels

SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zika virus-induced TNF-α signaling dysregulates expression of neurologic genes associated with psychiatric disorders. J Neuroinflammation. 2022 Apr 24; 19(1):100. Kung PL, Chou TW, Lindman M, Chang NP, Estevez I, Buckley BD, Atkins C, Daniels BP. PMID: 35462541; PMCID: PMC9036774.
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    2. Fibrillar α-synuclein induces neurotoxic astrocyte activation via RIP kinase signaling and NF-κB. Cell Death Dis. 2021 07 31; 12(8):756. Chou TW, Chang NP, Krishnagiri M, Patel AP, Lindman M, Angel JP, Kung PL, Atkins C, Daniels BP. PMID: 34333522; PMCID: PMC8325686.
      View in: PubMed   Mentions:
    3. Developing human pluripotent stem cell-based cerebral organoids with a controllable microglia ratio for modeling brain development and pathology. Stem Cell Reports. 2021 08 10; 16(8):1923-1937. Xu R, Boreland AJ, Li X, Erickson C, Jin M, Atkins C, Pang ZP, Daniels BP, Jiang P. PMID: 34297942; PMCID: PMC8365109.
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    4. Outcomes of RIP Kinase Signaling During Neuroinvasive Viral Infection. Curr Top Microbiol Immunol. 2020 Apr 07. Daniels BP, Oberst A. PMID: 32253569; PMCID: PMC7781604.
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    5. Astrocyte-T cell crosstalk regulates region-specific neuroinflammation. Glia. 2020 07; 68(7):1361-1374. Williams JL, Manivasagam S, Smith BC, Sim J, Vollmer LL, Daniels BP, Russell JH, Klein RS. PMID: 31961459; PMCID: PMC7317491.
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    6. RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity. Cell Rep. 2019 08 27; 28(9):2275-2287.e5. Orozco SL, Daniels BP, Yatim N, Messmer MN, Quarato G, Chen-Harris H, Cullen SP, Snyder AG, Ralli-Jain P, Frase S, Tait SWG, Green DR, Albert ML, Oberst A. PMID: 31461645; PMCID: PMC6857709.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    7. STING is required for host defense against neuropathological West Nile virus infection. PLoS Pathog. 2019 08; 15(8):e1007899. McGuckin Wuertz K, Treuting PM, Hemann EA, Esser-Nobis K, Snyder AG, Graham JB, Daniels BP, Wilkins C, Snyder JM, Voss KM, Oberst A, Lund J, Gale M. PMID: 31415679; PMCID: PMC6695101.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    8. Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity. Sci Immunol. 2019 06 21; 4(36). Snyder AG, Hubbard NW, Messmer MN, Kofman SB, Hagan CE, Orozco SL, Chiang K, Daniels BP, Baker D, Oberst A. PMID: 31227597; PMCID: PMC6831211.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    9. The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons. Immunity. 2019 01 15; 50(1):64-76.e4. Daniels BP, Kofman SB, Smith JR, Norris GT, Snyder AG, Kolb JP, Gao X, Locasale JW, Martinez J, Gale M, Loo YM, Oberst A. PMID: 30635240; PMCID: PMC6342485.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    10. RIPK3 Restricts Viral Pathogenesis via Cell Death-Independent Neuroinflammation. Cell. 2017 Apr 06; 169(2):301-313.e11. Daniels BP, Snyder AG, Olsen TM, Orozco S, Oguin TH, Tait SWG, Martinez J, Gale M, Loo YM, Oberst A. PMID: 28366204; PMCID: PMC5405738.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    11. Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection. J Clin Invest. 2017 Mar 01; 127(3):843-856. Daniels BP, Jujjavarapu H, Durrant DM, Williams JL, Green RR, White JP, Lazear HM, Gale M, Diamond MS, Klein RS. PMID: 28134626; PMCID: PMC5330728.
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    12. MLKL Activation Triggers NLRP3-Mediated Processing and Release of IL-1β Independently of Gasdermin-D. J Immunol. 2017 03 01; 198(5):2156-2164. Gutierrez KD, Davis MA, Daniels BP, Olsen TM, Ralli-Jain P, Tait SW, Gale M, Oberst A. PMID: 28130493; PMCID: PMC5321867.
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    13. Plasmodium falciparum Histidine-Rich Protein II Compromises Brain Endothelial Barriers and May Promote Cerebral Malaria Pathogenesis. mBio. 2016 06 07; 7(3). Pal P, Daniels BP, Oskman A, Diamond MS, Klein RS, Goldberg DE. PMID: 27273825; PMCID: PMC4959673.
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    14. CCR5 limits cortical viral loads during West Nile virus infection of the central nervous system. J Neuroinflammation. 2015 Dec 15; 12:233. Durrant DM, Daniels BP, Pasieka T, Dorsey D, Klein RS. PMID: 26667390; PMCID: PMC4678669.
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    15. The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity. Nat Med. 2015 Dec; 21(12):1464-72. Miner JJ, Daniels BP, Shrestha B, Proenca-Modena JL, Lew ED, Lazear HM, Gorman MJ, Lemke G, Klein RS, Diamond MS. PMID: 26523970; PMCID: PMC4674389.
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    16. Knocking on Closed Doors: Host Interferons Dynamically Regulate Blood-Brain Barrier Function during Viral Infections of the Central Nervous System. PLoS Pathog. 2015 Sep; 11(9):e1005096. Daniels BP, Klein RS. PMID: 26379171; PMCID: PMC4574746.
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    17. Interferon-λ restricts West Nile virus neuroinvasion by tightening the blood-brain barrier. Sci Transl Med. 2015 Apr 22; 7(284):284ra59. Lazear HM, Daniels BP, Pinto AK, Huang AC, Vick SC, Doyle SE, Gale M, Klein RS, Diamond MS. PMID: 25904743; PMCID: PMC4435724.
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    18. Chemokines Referee Inflammation within the Central Nervous System during Infection and Disease. Adv Med. 2014; 2014:806741. Durrant DM, Williams JL, Daniels BP, Klein RS. PMID: 26556427; PMCID: PMC4590974.
      View in: PubMed   Mentions:
    19. An expanded task battery in the Morris water maze reveals effects of Toxoplasma gondii infection on learning and memory in rats. Parasitol Int. 2015 Feb; 64(1):5-12. Daniels BP, Sestito SR, Rouse ST. PMID: 25220582.
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    20. IL-1R1 signaling regulates CXCL12-mediated T cell localization and fate within the central nervous system during West Nile Virus encephalitis. J Immunol. 2014 Oct 15; 193(8):4095-106. Durrant DM, Daniels BP, Klein RS. PMID: 25200953; PMCID: PMC4340598.
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    21. Viral pathogen-associated molecular patterns regulate blood-brain barrier integrity via competing innate cytokine signals. mBio. 2014 Aug 26; 5(5):e01476-14. Daniels BP, Holman DW, Cruz-Orengo L, Jujjavarapu H, Durrant DM, Klein RS. PMID: 25161189; PMCID: PMC4173776.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    22. Enhanced sphingosine-1-phosphate receptor 2 expression underlies female CNS autoimmunity susceptibility. J Clin Invest. 2014 Jun; 124(6):2571-84. Cruz-Orengo L, Daniels BP, Dorsey D, Basak SA, Grajales-Reyes JG, McCandless EE, Piccio L, Schmidt RE, Cross AH, Crosby SD, Klein RS. PMID: 24812668; PMCID: PMC4089451.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimals
    23. Targeting CXCR7/ACKR3 as a therapeutic strategy to promote remyelination in the adult central nervous system. J Exp Med. 2014 May 05; 211(5):791-9. Williams JL, Patel JR, Daniels BP, Klein RS. PMID: 24733828; PMCID: PMC4010893.
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    24. Immortalized human cerebral microvascular endothelial cells maintain the properties of primary cells in an in vitro model of immune migration across the blood brain barrier. J Neurosci Methods. 2013 Jan 15; 212(1):173-9. Daniels BP, Cruz-Orengo L, Pasieka TJ, Couraud PO, Romero IA, Weksler B, Cooper JA, Doering TL, Klein RS. PMID: 23068604; PMCID: PMC3641664.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    25. 2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo. PLoS Pathog. 2012; 8(5):e1002698. Szretter KJ, Daniels BP, Cho H, Gainey MD, Yokoyama WM, Gale M, Virgin HW, Klein RS, Sen GC, Diamond MS. PMID: 22589727; PMCID: PMC3349756.
      View in: PubMed   Mentions:
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