Adam Searleman

Title(s)	Assistant Clinical Professor, Radiology
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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The effect of cartilage dehydration and rehydration on quantitative ultrashort echo time biomarkers. Quant Imaging Med Surg. 2023 Oct 01; 13(10):6942-6951. Wan L, Searleman AC, Ma Y, Wong JH, Williams J, Murphy ME, Du J, Chang EY, Tang G. PMID: 37869338; PMCID: PMC10585582.

View in: PubMed Mentions:
Correction: Lombardi et al. AcidoCEST-UTE MRI Reveals an Acidic Microenvironment in Knee Osteoarthritis. Int. J. Mol. Sci. 2022, 23, 4466. Int J Mol Sci. 2023 Aug 02; 24(15). Lombardi AF, Ma Y, Jang H, Jerban S, Tang Q, Searleman AC, Meyer RS, Du J, Chang EY. PMID: 37569908; PMCID: PMC10418682.

View in: PubMed Mentions: Fields:
Bio Biochemistry Che Chemistry Mol Molecular Biology
AcidoCEST-UTE MRI Reveals an Acidic Microenvironment in Knee Osteoarthritis. Int J Mol Sci. 2022 Apr 18; 23(8). Lombardi AF, Ma Y, Jang H, Jerban S, Tang Q, Searleman AC, Meyer RS, Du J, Chang EY. PMID: 35457284; PMCID: PMC9027981.

View in: PubMed Mentions: 6 Fields:
Bio Biochemistry Che Chemistry Mol Molecular Biology
Translation:Humans
Evaluation of enzymatic proteoglycan loss and collagen degradation in human articular cartilage using ultrashort echo time-based biomarkers: A feasibility study. NMR Biomed. 2022 05; 35(5):e4664. Wan L, Cheng X, Searleman AC, Ma YJ, Wong JH, Meyer RS, Du J, Tang G, Chang EY. PMID: 34904305; PMCID: PMC9042587.

View in: PubMed Mentions: 4 Fields:
Dia Diagnostic Imaging Nuc Nuclear Medicine
Translation:Humans
Taspase1 orchestrates fetal liver hematopoietic stem cell and vertebrae fates by cleaving TFIIA. JCI Insight. 2021 08 09; 6(15). Niizuma H, Searleman AC, Takeda S, Armstrong SA, Park CY, Cheng EH, Hsieh JJ. PMID: 34156981; PMCID: PMC8410044.

View in: PubMed Mentions: 2 Fields:
Med Medicine (General)
Translation:Animals Cells
Incidental Liver Findings on Cross-sectional Imaging. Radiol Clin North Am. 2021 Jul; 59(4):569-590. Searleman AC, Aganovic L, Santillan CS. PMID: 34053606.

View in: PubMed Mentions: Fields:
Rad Radiology
Translation:Humans
Volumetric imaging of myelin in vivo using 3D inversion recovery-prepared ultrashort echo time cones magnetic resonance imaging. NMR Biomed. 2020 10; 33(10):e4326. Ma YJ, Searleman AC, Jang H, Fan SJ, Wong J, Xue Y, Cai Z, Chang EY, Corey-Bloom J, Du J. PMID: 32691472; PMCID: PMC7952008.

View in: PubMed Mentions: 7 Fields:
Dia Diagnostic Imaging Nuc Nuclear Medicine
Translation:Humans Animals Cells
Fast quantitative three-dimensional ultrashort echo time (UTE) Cones magnetic resonance imaging of major tissues in the knee joint using extended sprial sampling. NMR Biomed. 2020 10; 33(10):e4376. Wan L, Ma Y, Yang J, Jerban S, Searleman AC, Carl M, Le N, Chang EY, Tang G, Du J. PMID: 32667115; PMCID: PMC7952018.

View in: PubMed Mentions: 5 Fields:
Dia Diagnostic Imaging Nuc Nuclear Medicine
Translation:Humans
Inversion recovery zero echo time (IR-ZTE) imaging for direct myelin detection in human brain: a feasibility study. Quant Imaging Med Surg. 2020 May; 10(5):895-906. Jang H, Carl M, Ma Y, Searleman AC, Jerban S, Chang EY, Corey-Bloom J, Du J. PMID: 32489915; PMCID: PMC7242298.

View in: PubMed Mentions: 4
Whole-Brain Myelin Imaging Using 3D Double-Echo Sliding Inversion Recovery Ultrashort Echo Time (DESIRE UTE) MRI. Radiology. 2020 02; 294(2):362-374. Ma YJ, Searleman AC, Jang H, Wong J, Chang EY, Corey-Bloom J, Bydder GM, Du J. PMID: 31746689; PMCID: PMC6996715.

View in: PubMed Mentions: 26 Fields:
Rad Radiology
Translation:Humans Cells
Assessment of an in vitro model of rotator cuff degeneration using quantitative magnetic resonance and ultrasound imaging with biochemical and histological correlation. Eur J Radiol. 2019 Dec; 121:108706. Guo T, Ma YJ, High RA, Tang Q, Wong JH, Byra M, Searleman AC, To SC, Wan L, Le N, Le N, Du J, Chang EY. PMID: 31655315; PMCID: PMC6881559.

View in: PubMed Mentions: 2 Fields:
Rad Radiology
Translation:Humans
Inversion recovery UTE based volumetric myelin imaging in human brain using interleaved hybrid encoding. Magn Reson Med. 2020 03; 83(3):950-961. Jang H, Ma Y, Searleman AC, Carl M, Corey-Bloom J, Chang EY, Du J. PMID: 31532032; PMCID: PMC6879796.

View in: PubMed Mentions: 10 Fields:
Dia Diagnostic Imaging
Translation:Humans Cells
Volumetric mapping of bound and pore water as well as collagen protons in cortical bone using 3D ultrashort echo time cones MR imaging techniques. Bone. 2019 10; 127:120-128. Jerban S, Ma Y, Li L, Jang H, Wan L, Guo T, Searleman A, Chang EY, Du J. PMID: 31176044; PMCID: PMC6708764.

View in: PubMed Mentions: 23 Fields:
Met Metabolism Ort Orthopedics
Translation:Humans
Ultrashort echo time magnetic resonance imaging (UTE-MRI) of cortical bone correlates well with histomorphometric assessment of bone microstructure. Bone. 2019 06; 123:8-17. Jerban S, Ma Y, Wong JH, Nazaran A, Searleman A, Wan L, Williams J, Du J, Chang EY. PMID: 30877070; PMCID: PMC6504977.

View in: PubMed Mentions: 27 Fields:
Met Metabolism Ort Orthopedics
Translation:Humans
Fast quantitative 3D ultrashort echo time MRI of cortical bone using extended cones sampling. Magn Reson Med. 2019 07; 82(1):225-236. Wan L, Zhao W, Ma Y, Jerban S, Searleman AC, Carl M, Chang EY, Tang G, Du J. PMID: 30821032; PMCID: PMC7938871.

View in: PubMed Mentions: 27 Fields:
Dia Diagnostic Imaging
Translation:Humans Animals
Collagen proton fraction from ultrashort echo time magnetization transfer (UTE-MT) MRI modelling correlates significantly with cortical bone porosity measured with micro-computed tomography (μCT). NMR Biomed. 2019 02; 32(2):e4045. Jerban S, Ma Y, Wan L, Searleman AC, Jang H, Sah RL, Chang EY, Du J. PMID: 30549338; PMCID: PMC6324959.

View in: PubMed Mentions: 25 Fields:
Dia Diagnostic Imaging Nuc Nuclear Medicine
Translation:Humans
Whole knee joint T1 values measured in vivo at 3T by combined 3D ultrashort echo time cones actual flip angle and variable flip angle methods. Magn Reson Med. 2019 03; 81(3):1634-1644. Ma YJ, Zhao W, Wan L, Guo T, Searleman A, Jang H, Chang EY, Du J. PMID: 30443925; PMCID: PMC6347520.

View in: PubMed Mentions: 35 Fields:
Dia Diagnostic Imaging
Translation:Humans
True phase quantitative susceptibility mapping using continuous single-point imaging: a feasibility study. Magn Reson Med. 2019 03; 81(3):1907-1914. Jang H, Lu X, Carl M, Searleman AC, Jerban S, Ma Y, von Drygalski A, Chang EY, Du J. PMID: 30325058; PMCID: PMC6347538.

View in: PubMed Mentions: 14 Fields:
Dia Diagnostic Imaging
Translation:Humans
3D adiabatic T1ρ prepared ultrashort echo time cones sequence for whole knee imaging. Magn Reson Med. 2018 10; 80(4):1429-1439. Ma YJ, Carl M, Searleman A, Lu X, Chang EY, Du J. PMID: 29493004; PMCID: PMC6097905.

View in: PubMed Mentions: 36 Fields:
Dia Diagnostic Imaging
Translation:Humans
Simultaneous quantitative susceptibility mapping (QSM) and R2* for high iron concentration quantification with 3D ultrashort echo time sequences: An echo dependence study. Magn Reson Med. 2018 04; 79(4):2315-2322. Lu X, Ma Y, Chang EY, He Q, Searleman A, von Drygalski A, Du J. PMID: 29314215; PMCID: PMC5811338.

View in: PubMed Mentions: 17 Fields:
Dia Diagnostic Imaging
Translation:Humans
Yet more evidence that myelin protons can be directly imaged with UTE sequences on a clinical 3T scanner: Bicomponent T2* analysis of native and deuterated ovine brain specimens. Magn Reson Med. 2018 08; 80(2):538-547. Fan SJ, Ma Y, Zhu Y, Searleman A, Szeverenyi NM, Bydder GM, Du J. PMID: 29271083; PMCID: PMC5910230.

View in: PubMed Mentions: 15 Fields:
Dia Diagnostic Imaging
Translation:Animals Cells
Interpretive Differences Between Patients and Radiologists Regarding the Diagnostic Confidence Associated With Commonly Used Phrases in the Radiology Report. AJR Am J Roentgenol. 2018 Jan; 210(1):123-126. Mityul MI, Gilcrease-Garcia B, Searleman A, Demertzis JL, Gunn AJ. PMID: 29023151.

View in: PubMed Mentions: 4 Fields:
Rad Radiology
Translation:Humans
HER2 activating mutations are targets for colorectal cancer treatment. Cancer Discov. 2015 Aug; 5(8):832-41. Kavuri SM, Jain N, Galimi F, Cottino F, Leto SM, Migliardi G, Searleman AC, Shen W, Monsey J, Trusolino L, Jacobs SA, Bertotti A, Bose R. PMID: 26243863; PMCID: PMC4527087.

View in: PubMed Mentions: 143 Fields:
Neo Neoplasms
Translation:Humans Animals Cells
Statistically identifying tumor suppressors and oncogenes from pan-cancer genome-sequencing data. Bioinformatics. 2015 Nov 15; 31(22):3561-8. Kumar RD, Searleman AC, Swamidass SJ, Griffith OL, Bose R. PMID: 26209800; PMCID: PMC4757952.

View in: PubMed Mentions: 23 Fields:
Com Computational Biology
Translation:Humans
Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription. J Clin Invest. 2015 Mar 02; 125(3):1203-14. Takeda S, Sasagawa S, Oyama T, Searleman AC, Westergard TD, Cheng EH, Hsieh JJ. PMID: 25664857; PMCID: PMC4362222.

View in: PubMed Mentions: 12 Fields:
Med Medicine (General)
Translation:Animals Cells
Tissue phosphoproteomics with PolyMAC identifies potential therapeutic targets in a transgenic mouse model of HER2 positive breast cancer. Electrophoresis. 2014 Dec; 35(24):3463-9. Searleman AC, Iliuk AB, Collier TS, Chodosh LA, Tao WA, Bose R. PMID: 24723360; PMCID: PMC4193948.

View in: PubMed Mentions: 3 Fields:
Che Chemistry Techniques
Translation:Animals
Activating HER2 mutations in HER2 gene amplification negative breast cancer. Cancer Discov. 2013 Feb; 3(2):224-37. Bose R, Kavuri SM, Searleman AC, Shen W, Shen D, Koboldt DC, Monsey J, Goel N, Aronson AB, Li S, Ma CX, Ding L, Mardis ER, Ellis MJ. PMID: 23220880; PMCID: PMC3570596.

View in: PubMed Mentions: 377 Fields:
Neo Neoplasms
Translation:Humans Animals Cells
A pharmacologic inhibitor of the protease Taspase1 effectively inhibits breast and brain tumor growth. Cancer Res. 2012 Feb 01; 72(3):736-46. Chen DY, Lee Y, Van Tine BA, Searleman AC, Westergard TD, Liu H, Tu HC, Takeda S, Dong Y, Piwnica-Worms DR, Oh KJ, Korsmeyer SJ, Hermone A, Gussio R, Shoemaker RH, Cheng EH, Hsieh JJ. PMID: 22166309; PMCID: PMC3325786.

View in: PubMed Mentions: 23 Fields:
Neo Neoplasms
Translation:Humans Animals Cells
Long-term cognitive decline in older subjects was not attributable to noncardiac surgery or major illness. Anesthesiology. 2009 Nov; 111(5):964-70. Avidan MS, Searleman AC, Storandt M, Barnett K, Vannucci A, Saager L, Xiong C, Grant EA, Kaiser D, Morris JC, Evers AS. PMID: 19786858; PMCID: PMC2783989.

View in: PubMed Mentions: 61 Fields:
Ane Anesthesiology
Translation:Humans
Prevalence of undiagnosed obstructive sleep apnea among adult surgical patients in an academic medical center. Sleep Med. 2009 Aug; 10(7):753-8. Finkel KJ, Searleman AC, Tymkew H, Tanaka CY, Saager L, Safer-Zadeh E, Bottros M, Selvidge JA, Jacobsohn E, Pulley D, Duntley S, Becker C, Avidan MS. PMID: 19186102.

View in: PubMed Mentions: 134 Fields:
Neu Neurology Psy Psychophysiology
Translation:Humans
Anesthesia awareness and the bispectral index. N Engl J Med. 2008 Mar 13; 358(11):1097-108. Avidan MS, Zhang L, Burnside BA, Finkel KJ, Searleman AC, Selvidge JA, Saager L, Turner MS, Rao S, Bottros M, Hantler C, Jacobsohn E, Evers AS. PMID: 18337600.

View in: PubMed Mentions: 197 Fields:
Med Medicine (General)
Translation:Humans
Suspected autoimmune disorders and left-handedness: evidence from individuals with diabetes. Crohn's disease and ulcerative colitis. Neuropsychologia. 1987; 25(2):367-74. Searleman A, Fugagli AK. PMID: 3601042.

View in: PubMed Mentions: 12 Fields:
Neu Neurology Psy Psychology
Translation:Humans