Takayuki Morimoto

Title(s)Postdoctoral Scholar, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    1. Immunotherapy using allogenic NK cells downregulates mitochondrial-related genes and inhibits the OXPHOS system of malignant meningioma. Biomed Pharmacother. 2025 Jun; 187:118099. Maeoka R, Matsuda R, Nakazawa T, Mochida Y, Ouji-Sageshima N, Yamada K, Morimoto T, Takeshima Y, Yamada S, Nishimura F, Park YS, Ito T, Nakagawa I. PMID: 40300389.
      View in: PubMed   Mentions:    Fields:    
    2. Interfinger Differences in Pulse Oximetry Signal-Derived Peripheral Perfusion Index: A Single-Center Exploratory Study. Cureus. 2025 Apr; 17(4):e82131. Shintani R, Sekino M, Sato S, Morimoto T, Kaneko S, Iwasaki N, Araki H, Ichinomiya T, Higashijima U, Hara T. PMID: 40357060; PMCID: PMC12067496.
      View in: PubMed   Mentions:
    3. Systemic inflammation response index predicts overall survival in patients undergoing stereotactic radiosurgery for brain metastasis from non-small cell lung cancer. J Radiat Res. 2025 Mar 24; 66(2):129-136. Matsuda R, Tamamoto T, Inooka N, Hontsu S, Doi A, Maeoka R, Nakazawa T, Morimoto T, Yamaki K, Miura S, Morisaki Y, Yokoyama S, Kotsugi M, Takeshima Y, Isohashi F, Nakagawa I. PMID: 39967449; PMCID: PMC11932349.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Anesthetic management in the lateral position in a patient with Parkinson's disease who developed severe long-seated forward flexion with the face buried between the knees: a case report. JA Clin Rep. 2025 Feb 14; 11(1):9. Morimoto T, Ono M, Harada Y, Ichinomiya T, Higashijima U, Hara T. PMID: 39951202; PMCID: PMC11828767.
      View in: PubMed   Mentions:
    5. Kissing balloon treatment for stenosis of the internal and external carotid artery orifice associated with moyamoya disease: illustrative case. J Neurosurg Case Lessons. 2024 Dec 02; 8(23). Morimoto T, Fujimoto K, Ko SC, Nishioka T, Tokunaga H. PMID: 39622020; PMCID: PMC11616142.
      View in: PubMed   Mentions:
    6. Vertebral artery stump syndrome associated with a bihemispheric posterior inferior cerebellar artery. Surg Neurol Int. 2024; 15:350. Morimoto T, Fujimoto K, Ko SC, Nishioka T, Tokunaga H. PMID: 39372974; PMCID: PMC11450790.
      View in: PubMed   Mentions:
    7. A case of spontaneous direct vertebral artery - External vertebral venous plexus fistula in the upper cervical portion. Surg Neurol Int. 2024; 15:351. Morimoto T, Fujimoto K, Ko S, Nishioka T, Tokunaga H. PMID: 39373003; PMCID: PMC11450823.
      View in: PubMed   Mentions:
    8. Combined endovascular therapy and surgery for central giant cell granuloma in the temporal bone: A case report. Surg Neurol Int. 2024; 15:335. Morimoto T, Ko SC, Shimada K, Nishioka T, Tokunaga H. PMID: 39372987; PMCID: PMC11450781.
      View in: PubMed   Mentions:
    9. Effect of Intraoperative Ventricular Opening on Recurrence Patterns Following Bis-Chloroethyl-Nitrosourea Wafer Implantation for Newly Diagnosed Glioblastoma. J Korean Neurosurg Soc. 2025 Jan; 68(1):60-66. Matsuda R, Maeoka R, Morimoto T, Nakazawa T, Tokuda N, Kotsugi M, Takeshima Y, Tamura K, Yamada S, Nishimura F, Park YS, Nakagawa I. PMID: 39081094; PMCID: PMC11725460.
      View in: PubMed   Mentions:
    10. Characterization of HIF-1α Knockout Primary Human Natural Killer Cells Including Populations in Allogeneic Glioblastoma. Int J Mol Sci. 2024 May 28; 25(11). Nakazawa T, Morimoto T, Maeoka R, Yamada K, Matsuda R, Nakamura M, Nishimura F, Yamada S, Park YS, Tsujimura T, Nakagawa I. PMID: 38892084; PMCID: PMC11173110.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. Pre-treatment systemic inflammation response index and systemic immune inflammation in patients with primary central nerve system lymphoma as a useful prognostic indicator. J Neurooncol. 2024 Jul; 168(3):487-494. Matsuda R, Maeoka R, Morimoto T, Nakazawa T, Morisaki Y, Yokoyama S, Kotsugi M, Takeshima Y, Yamada S, Nishimura F, Park YS, Nakagawa I. PMID: 38658464.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    12. Preoperative Blood Counts Predict Overall Survival in Patients Undergoing Surgical Removal of Brain Metastasis. World Neurosurg. 2024 06; 186:e727-e733. Matsuda R, Maeoka R, Morimoto T, Nakazawa T, Morisaki Y, Nakase K, Yokoyama S, Kotsugi M, Takeshima Y, Yamada S, Nakagawa I. PMID: 38636630.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    13. Bulk RNA sequencing reveals the comprehensive genetic characteristics of human cord blood-derived natural killer cells. Regen Ther. 2024 Mar; 25:367-376. Morimoto T, Nakazawa T, Maeoka R, Matsuda R, Nakamura M, Nishimura F, Yamada S, Nakagawa I, Park YS, Tsujimura T. PMID: 38405180; PMCID: PMC10891285.
      View in: PubMed   Mentions: 1  
    14. Antitumor Effects of Intravenous Natural Killer Cell Infusion in an Orthotopic Glioblastoma Xenograft Murine Model and Gene Expression Profile Analysis. Int J Mol Sci. 2024 Feb 19; 25(4). Morimoto T, Nakazawa T, Matsuda R, Maeoka R, Nishimura F, Nakamura M, Yamada S, Park YS, Tsujimura T, Nakagawa I. PMID: 38397112; PMCID: PMC10889440.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    15. Clinical Results and Hematologic Predictors of Linear Accelerator-Based Stereotactic Radiosurgery or Fractionated Stereotactic Radiotherapy for Brain Metastasis in Patients Aged 75 Years or Older: A Retrospective Study. World Neurosurg. 2024 03; 183:e944-e952. Matsuda R, Hasegawa M, Tamamoto T, Inooka N, Morimoto T, Maeoka R, Nakazawa T, Ochi T, Miyasaka T, Hontsu S, Yamaki K, Miura S, Yamada S, Nishimura F, Nakagawa I, Park YS, Nakase H. PMID: 38244685.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Traumatic intracranial aneurysm in a distal posterior cerebral artery: A case report and literature review. Surg Neurol Int. 2023; 14:428. Yamada K, Morimoto T, Fujimoto K, Nishioka T, Tokunaga H. PMID: 38213445; PMCID: PMC10783693.
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    17. Therapeutic Anti-KIR Antibody of 1-7F9 Attenuates the Antitumor Effects of Expanded and Activated Human Primary Natural Killer Cells on In Vitro Glioblastoma-like Cells and Orthotopic Tumors Derived Therefrom. Int J Mol Sci. 2023 Sep 16; 24(18). Maeoka R, Nakazawa T, Matsuda R, Morimoto T, Shida Y, Yamada S, Nishimura F, Nakamura M, Nakagawa I, Park YS, Tsujimura T, Nakase H. PMID: 37762486; PMCID: PMC10531877.
      View in: PubMed   Mentions: 1     Fields:    
    18. CIS deletion by CRISPR/Cas9 enhances human primary natural killer cell functions against allogeneic glioblastoma. J Exp Clin Cancer Res. 2023 Aug 10; 42(1):205. Nakazawa T, Morimoto T, Maeoka R, Matsuda R, Nakamura M, Nishimura F, Ouji N, Yamada S, Nakagawa I, Park YS, Ito T, Nakase H, Tsujimura T. PMID: 37563692; PMCID: PMC10413513.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    19. Local administration of shikonin improved the overall survival in orthotopic murine glioblastoma models with temozolomide resistance. Biomed Pharmacother. 2023 Oct; 166:115296. Maeoka R, Ouji Y, Nakazawa T, Matsuda R, Morimoto T, Yokoyama S, Yamada S, Nishimura F, Nakagawa I, Park YS, Yoshikawa M, Nakase H. PMID: 37557011.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    20. An efficient feeder-free and chemically-defined expansion strategy for highly purified natural killer cells derived from human cord blood. Regen Ther. 2023 Dec; 24:32-42. Nakazawa T, Maeoka R, Morimoto T, Matsuda R, Nakamura M, Nishimura F, Yamada S, Nakagawa I, Park YS, Ito T, Nakase H, Tsujimura T. PMID: 37303464; PMCID: PMC10247952.
      View in: PubMed   Mentions: 2  
    21. Natural Killer Cell-Based Immunotherapy against Glioblastoma. Int J Mol Sci. 2023 Jan 20; 24(3). Morimoto T, Nakazawa T, Maeoka R, Nakagawa I, Tsujimura T, Matsuda R. PMID: 36768432; PMCID: PMC9916747.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    22. Response to a letter to the editor by Aoki et al.: Critical considerations, including overfitting in regression models and confounding in study designs for delirium follow-up. J Anesth. 2023 04; 37(2):323-324. Kaneko S, Sato S, Morimoto T, Ichinomiya T, Murata H, Yoshitomi O, Hara T. PMID: 36670281.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Management of Combined Cardiac Surgery Using Cardiopulmonary Bypass With Acute Normovolemic Hemodilution in a Jehovah's Witness: A Case Report. Cureus. 2023 Jan; 15(1):e33442. Morimoto T, Ichinomiya T, Murata H, Sekino M, Hara T. PMID: 36751150; PMCID: PMC9897691.
      View in: PubMed   Mentions:
    24. Intraoperative Ventricular Opening has No Effect on Complication Development Following BCNU Wafer Implantation for Malignant Glioma. World Neurosurg. 2023 03; 171:e707-e713. Matsuda R, Maeoka R, Tokuda N, Nakazawa T, Morimoto T, Kotsugi M, Takeshima Y, Tamura K, Yamada S, Nishimura F, Nakagawa I, Park YS, Nakase H. PMID: 36574919.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. Effect of remimazolam on the incidence of delirium after transcatheter aortic valve implantation under general anesthesia: a retrospective exploratory study. J Anesth. 2023 04; 37(2):210-218. Kaneko S, Morimoto T, Ichinomiya T, Murata H, Yoshitomi O, Hara T. PMID: 36463532.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    26. Capability of Human Dendritic Cells Pulsed with Autologous Induced Pluripotent Stem Cell Lysate to Induce Cytotoxic T Lymphocytes against HLA-A33-Matched Cancer Cells. Int J Mol Sci. 2022 Oct 27; 23(21). Nakazawa T, Maeoka R, Morimoto T, Matsuda R, Nakamura M, Nishimura F, Yamada S, Nakagawa I, Park YS, Nakase H, Tsujimura T. PMID: 36361783; PMCID: PMC9654950.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    27. Long-Term Survival after Linac-Based Stereotactic Radiosurgery and Radiotherapy with a Micro-Multileaf Collimator for Brain Metastasis. Curr Oncol. 2022 08 24; 29(9):6068-6076. Matsuda R, Hasegawa M, Tamamoto T, Inooka N, Nikimoto M, Ochi T, Miyasaka T, Hontsu S, Yamaki K, Miura S, Morimoto T, Mitsui T, Furuta T, Yokoyama S, Kotsugi M, Yamada S, Nakagawa I, Park YS, Nakase H. PMID: 36135046; PMCID: PMC9497847.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    28. Impact of surgical factors on delayed hyponatremia in patients with nonfunctioning pituitary adenoma after endonasal endoscopic transsphenoidal procedure. Endocrine. 2022 11; 78(2):354-362. Tanaka H, Nishimura F, Nakase K, Kakutani M, Yokoyama S, Morimoto T, Kim T, Park YS, Nakagawa I, Yamada S, Tamura K, Matsuda R, Takeshima Y, Kotsugi M, Nakase H. PMID: 35984619; PMCID: PMC9584842.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. Establishment of an efficient ex vivo expansion strategy for human natural killer cells stimulated by defined cytokine cocktail and antibodies against natural killer cell activating receptors. Regen Ther. 2022 Dec; 21:185-191. Nakazawa T, Morimoto T, Maeoka R, Matsuda R, Nakamura M, Nishimura F, Yamada S, Nakagawa I, Park YS, Nakase H, Tsujimura T. PMID: 35919498; PMCID: PMC9309574.
      View in: PubMed   Mentions: 13  
    30. Combined Treatment With Radiotherapy and Immunotherapy for Isocitrate Dehydrogenase Mutant Brainstem Glioma in Adult: A Case Report. Brain Tumor Res Treat. 2022 Apr; 10(2):129-133. Morimoto T, Matsuda R, Nakazawa T, Nishimura F, Nakagawa I. PMID: 35545834; PMCID: PMC9098982.
      View in: PubMed   Mentions: 2  
    31. Awake Craniotomy for Subcortical Brain Metastasis Beneath the Speech Center: A Technical Case Report. Anticancer Res. 2022 Mar; 42(3):1641-1644. Matsuda R, Kotsugi M, Nakase K, Morimoto T, Nishimura F, Nakagawa I, Nakase H. PMID: 35220263.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. Awake Surgery for Local Recurrence of Brain Metastasis in the Precentral Gyrus After Fractionated Stereotactic Radiotherapy: A Technical Case Report. Anticancer Res. 2022 Feb; 42(2):1151-1155. Matsuda R, Sato F, Kotsugi M, Morimoto T, Nishimura F, Nakagawa I, Nakase H. PMID: 35093919.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. Salvage Surgical Resection after Linac-Based Stereotactic Radiosurgery for Newly Diagnosed Brain Metastasis. Curr Oncol. 2021 12 09; 28(6):5255-5265. Matsuda R, Morimoto T, Tamamoto T, Inooka N, Ochi T, Miyasaka T, Hontsu S, Yamaki K, Miura S, Takeshima Y, Tamura K, Yamada S, Nishimura F, Nakagawa I, Motoyama Y, Park YS, Hasegawa M, Nakase H. PMID: 34940078; PMCID: PMC8699906.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    34. Evaluation of Comprehensive Gene Expression and NK Cell-Mediated Killing in Glioblastoma Cell Line-Derived Spheroids. Cancers (Basel). 2021 Sep 29; 13(19). Morimoto T, Nakazawa T, Matsuda R, Nishimura F, Nakamura M, Yamada S, Nakagawa I, Park YS, Tsujimura T, Nakase H. PMID: 34638384; PMCID: PMC8508082.
      View in: PubMed   Mentions: 11  
    35. Ex Vivo Expanded and Activated Natural Killer Cells Prolong the Overall Survival of Mice with Glioblastoma-like Cell-Derived Tumors. Int J Mol Sci. 2021 Sep 15; 22(18). Shida Y, Nakazawa T, Matsuda R, Morimoto T, Nishimura F, Nakamura M, Maeoka R, Yamada S, Nakagawa I, Park YS, Yasukawa M, Tojo T, Tsujimura T, Nakase H. PMID: 34576141; PMCID: PMC8472834.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    36. CRISPR-Cas9-Mediated TIM3 Knockout in Human Natural Killer Cells Enhances Growth Inhibitory Effects on Human Glioma Cells. Int J Mol Sci. 2021 Mar 28; 22(7). Morimoto T, Nakazawa T, Matsuda R, Nishimura F, Nakamura M, Yamada S, Nakagawa I, Park YS, Tsujimura T, Nakase H. PMID: 33800561; PMCID: PMC8036491.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    37. Arabidopsis SMN2/HEN2, Encoding DEAD-Box RNA Helicase, Governs Proper Expression of the Resistance Gene SMN1/RPS6 and Is Involved in Dwarf, Autoimmune Phenotypes of mekk1 and mpk4 Mutants. Plant Cell Physiol. 2020 Aug 01; 61(8):1507-1516. Takagi M, Iwamoto N, Kubo Y, Morimoto T, Takagi H, Takahashi F, Nishiuchi T, Tanaka K, Taji T, Kaminaka H, Shinozaki K, Akimitsu K, Terauchi R, Shirasu K, Ichimura K. PMID: 32467981.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    38. KHYG-1 Cells With EGFRvIII-specific CAR Induced a Pseudoprogression-like Feature in Subcutaneous Tumours Derived from Glioblastoma-like Cells. Anticancer Res. 2020 Jun; 40(6):3231-3237. Nakazawa T, Murakami T, Natsume A, Nishimura F, Morimoto T, Matsuda R, Nakamura M, Yamada S, Nakagawa I, Park YS, Motoyama Y, Tsujimura T, Wakabayashi T, Nakase H. PMID: 32487617.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    39. Effect of CRISPR/Cas9-Mediated PD-1-Disrupted Primary Human Third-Generation CAR-T Cells Targeting EGFRvIII on In Vitro Human Glioblastoma Cell Growth. Cells. 2020 04 16; 9(4). Nakazawa T, Natsume A, Nishimura F, Morimoto T, Matsuda R, Nakamura M, Yamada S, Nakagawa I, Motoyama Y, Park YS, Tsujimura T, Wakabayashi T, Nakase H. PMID: 32316275; PMCID: PMC7227242.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    40. Disruption of the MAMP-Induced MEKK1-MKK1/MKK2-MPK4 Pathway Activates the TNL Immune Receptor SMN1/RPS6. Plant Cell Physiol. 2019 Apr 01; 60(4):778-787. Takagi M, Hamano K, Takagi H, Morimoto T, Akimitsu K, Terauchi R, Shirasu K, Ichimura K. PMID: 30590768.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    41. Acetoxybenzhydrols as highly active and stable analogues of 1'S-1'-acetoxychavicol, a potent antiallergic principal from Alpinia galanga. Bioorg Med Chem Lett. 2009 Jun 01; 19(11):2944-6. Yasuhara T, Manse Y, Morimoto T, Qilong W, Matsuda H, Yoshikawa M, Muraoka O. PMID: 19414259.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    42. A simple and efficient iron-catalyzed intramolecular hydroamination of unactivated olefins. Angew Chem Int Ed Engl. 2006 Apr 28; 45(18):2938-41. Komeyama K, Morimoto T, Takaki K. PMID: 16555362.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    43. Development of injectable O-15 oxygen and estimation of rat OEF. J Cereb Blood Flow Metab. 2003 Jun; 23(6):671-6. Magata Y, Temma T, Iida H, Ogawa M, Mukai T, Iida Y, Morimoto T, Konishi J, Saji H. PMID: 12796715.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
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