Stacia Keller

SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Opaganib Promotes Weight Loss and Suppresses High-Fat Diet-Induced Obesity and Glucose Intolerance. Diabetes Metab Syndr Obes. 2025; 18:969-983. Maines LW, Keller SN, Smith RA, Smith CD. PMID: 40191829; PMCID: PMC11971975.
      View in: PubMed   Mentions:
    2. Opaganib Downregulates N-Myc Expression and Suppresses In Vitro and In Vivo Growth of Neuroblastoma Cells. Cancers (Basel). 2024 May 05; 16(9). Maines LW, Keller SN, Smith RA, Schrecengost RS, Smith CD. PMID: 38730731; PMCID: PMC11082966.
      View in: PubMed   Mentions:
    3. The Sphingolipid-Modulating Drug Opaganib Protects against Radiation-Induced Lung Inflammation and Fibrosis: Potential Uses as a Medical Countermeasure and in Cancer Radiotherapy. Int J Mol Sci. 2024 Feb 15; 25(4). Maines LW, Keller SN, Smith RA, Green CL, Smith CD. PMID: 38396999; PMCID: PMC10888706.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsPHPublic Health
    4. Opaganib (ABC294640) Induces Immunogenic Tumor Cell Death and Enhances Checkpoint Antibody Therapy. Int J Mol Sci. 2023 Nov 29; 24(23). Maines LW, Keller SN, Smith CD. PMID: 38069222; PMCID: PMC10706694.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    5. The Sphingosine Kinase 2 Inhibitor Opaganib Protects Against Acute Kidney Injury in Mice. Int J Nephrol Renovasc Dis. 2022; 15:323-334. Maines LW, Green CL, Keller SN, Fitzpatrick LR, Smith CD. PMID: 36420520; PMCID: PMC9677921.
      View in: PubMed   Mentions: 1  
    6. Opaganib Protects against Radiation Toxicity: Implications for Homeland Security and Antitumor Radiotherapy. Int J Mol Sci. 2022 Oct 29; 23(21). Maines LW, Schrecengost RS, Zhuang Y, Keller SN, Smith RA, Green CL, Smith CD. PMID: 36361977; PMCID: PMC9655569.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    7. Recent Progress in the Development of Opaganib for the Treatment of Covid-19. Drug Des Devel Ther. 2022; 16:2199-2211. Smith CD, Maines LW, Keller SN, Katz Ben-Yair V, Fathi R, Plasse TF, Levitt ML. PMID: 35855741; PMCID: PMC9288228.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCellsPHPublic Health
    8. In Vitro and In Vivo Antitumor and Anti-Inflammatory Capabilities of the Novel GSK3 and CDK9 Inhibitor ABC1183. J Pharmacol Exp Ther. 2018 04; 365(1):107-116. Schrecengost RS, Green CL, Zhuang Y, Keller SN, Smith RA, Maines LW, Smith CD. PMID: 29434052; PMCID: PMC5830635.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression. Mol Cancer Res. 2015 Dec; 13(12):1591-601. Schrecengost RS, Keller SN, Schiewer MJ, Knudsen KE, Smith CD. PMID: 26271487; PMCID: PMC4685021.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    10. 2-Amino-4-methyl-5-phenylethyl substituted-7-N-benzyl-pyrrolo[2,3-d]pyrimidines as novel antitumor antimitotic agents that also reverse tumor resistance. Bioorg Med Chem. 2011 Jul 15; 19(14):4355-65. Gangjee A, Namjoshi OA, Keller SN, Smith CD. PMID: 21680190; PMCID: PMC3138178.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2. J Pharmacol Exp Ther. 2010 Apr; 333(1):129-39. French KJ, Zhuang Y, Maines LW, Gao P, Wang W, Beljanski V, Upson JJ, Green CL, Keller SN, Smith CD. PMID: 20061445; PMCID: PMC2846016.
      View in: PubMed   Mentions: 177     Fields:    Translation:HumansAnimalsCells
    12. Suppression of ulcerative colitis in mice by orally available inhibitors of sphingosine kinase. Dig Dis Sci. 2008 Apr; 53(4):997-1012. Maines LW, Fitzpatrick LR, French KJ, Zhuang Y, Xia Z, Keller SN, Upson JJ, Smith CD. PMID: 18058233; PMCID: PMC2660406.
      View in: PubMed   Mentions: 84     Fields:    
    13. Discovery and characterization of inhibitors of human palmitoyl acyltransferases. Mol Cancer Ther. 2006 Jul; 5(7):1647-59. Ducker CE, Griffel LK, Smith RA, Keller SN, Zhuang Y, Xia Z, Diller JD, Smith CD. PMID: 16891450; PMCID: PMC2888271.
      View in: PubMed   Mentions: 38     Fields:    
    14. Antitumor activity of sphingosine kinase inhibitors. J Pharmacol Exp Ther. 2006 Aug; 318(2):596-603. French KJ, Upson JJ, Keller SN, Zhuang Y, Yun JK, Smith CD. PMID: 16632640.
      View in: PubMed   Mentions: 100     Fields:    
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