Matteo Castelli

Title(s)	Postdoctoral Scholar, Molecular Biology
School	Vc-academic Affairs
Address	9500 Gilman Drive # La Jolla CA 92093
ORCID	0000-0002-3673-0262
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Biography

Education and Training

University of Milan, Milan, Italy	B.Sc.	10/2018	Chemistry
University of Pavia, Pavia, Italy	M.Sc.	07/2020	Chemistry
University of Pavia, Pavia, Italy	Ph.D.	09/2023	Computational Biophysics

Awards and Honors

Italian Chemistry Society

2022

Italian Chemistry Society oral presentation travel grant

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Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Molecular mechanisms of chaperone-directed protein folding: Insights from atomistic simulations. Protein Sci. 2023 Dec 25; 33(3):e4880. Castelli M, Magni A, Bonollo G, Pavoni S, Frigerio F, Oliveira ASF, Cinquini F, Serapian SA, Colombo G. PMID: 38145386; PMCID: PMC10895457.

View in: PubMed Mentions: 1 Fields:
Bio Biochemistry
Decrypting Allostery in Membrane-Bound K-Ras4B Using Complementary In Silico Approaches Based on Unbiased Molecular Dynamics Simulations. J Am Chem Soc. 2024 Jan 10; 146(1):901-919. Castelli M, Marchetti F, Osuna S, F Oliveira AS, Mulholland AJ, Serapian SA, Colombo G. PMID: 38116743; PMCID: PMC10785808.

View in: PubMed Mentions: Fields:
Che Chemistry
Translation:Cells
NLRP3 monomer functional dynamics: From the effects of allosteric binding to implications for drug design. Int J Biol Macromol. 2023 Aug 15; 246:125609. Casali E, Serapian SA, Gianquinto E, Castelli M, Bertinaria M, Spyrakis F, Colombo G. PMID: 37394218.

View in: PubMed Mentions: Fields:
Bio Biochemistry Mol Molecular Biology
How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view. Structure. 2023 08 03; 31(8):987-1004.e8. Castelli M, Yan P, Rodina A, Digwal CS, Panchal P, Chiosis G, Moroni E, Colombo G. PMID: 37343552; PMCID: PMC10526633.

View in: PubMed Mentions: 5 Fields:
Bio Biochemistry Bio Biotechnology Mol Molecular Biology
Translation:Cells
PhosY-secretome profiling combined with kinase-substrate interaction screening defines active c-Src-driven extracellular signaling. Cell Rep. 2023 06 27; 42(6):112539. Backe SJ, Votra SD, Stokes MP, Sebestyén E, Castelli M, Torielli L, Colombo G, Woodford MR, Mollapour M, Bourboulia D. PMID: 37243593; PMCID: PMC10569185.

View in: PubMed Mentions: 2 Fields:
Cel Cell Biology Mol Molecular Biology
Translation:Cells
AlphaFold predicted structure of the Hsp90-like domains of the neurodegeneration linked protein sacsin reveals key residues for ATPase activity. Front Mol Biosci. 2022; 9:1074714. Perna L, Castelli M, Frasnetti E, Romano LEL, Colombo G, Prodromou C, Chapple JP. PMID: 36710881; PMCID: PMC9880540.

View in: PubMed Mentions:
Phosphorylation of the Hsp90 Co-Chaperone Hop Changes its Conformational Dynamics and Biological Function. J Mol Biol. 2023 02 01; 435(3):167931. Castelli M, Bhattacharya K, Abboud E, Serapian SA, Picard D, Colombo G. PMID: 36572238.

View in: PubMed Mentions: 3 Fields:
Mol Molecular Biology
Translation:Humans Cells
Studying the Dynamics of a Complex G-Quadruplex System: Insights into the Comparison of MD and NMR Data. J Chem Theory Comput. 2022 Jul 12; 18(7):4515-4528. Castelli M, Doria F, Freccero M, Colombo G, Moroni E. PMID: 35666124; PMCID: PMC9281369.

View in: PubMed Mentions: 1 Fields:
Bio Biochemistry Che Chemistry
Translation:Humans Cells
Protein Allostery and Ligand Design: Computational Design Meets Experiments to Discover Novel Chemical Probes. J Mol Biol. 2022 09 15; 434(17):167468. Triveri A, Sanchez-Martin C, Torielli L, Serapian SA, Marchetti F, D'Acerno G, Pirota V, Castelli M, Moroni E, Ferraro M, Quadrelli P, Rasola A, Colombo G. PMID: 35101454.

View in: PubMed Mentions: 2 Fields:
Mol Molecular Biology
Translation:Humans Cells
The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect. Nat Struct Mol Biol. 2021 08; 28(8):662-670. Woodford MR, Baker-Williams AJ, Sager RA, Backe SJ, Blanden AR, Hashmi F, Kancherla P, Gori A, Loiselle DR, Castelli M, Serapian SA, Colombo G, Haystead TA, Jensen SM, Stetler-Stevenson WG, Loh SN, Schmidt LS, Linehan WM, Bah A, Bourboulia D, Bratslavsky G, Mollapour M. PMID: 34381247; PMCID: PMC9278990.

View in: PubMed Mentions: 14 Fields:
Mol Molecular Biology
Translation:Humans Cells
New perspectives in cancer drug development: computational advances with an eye to design. RSC Med Chem. 2021 Sep 23; 12(9):1491-1502. Castelli M, Serapian SA, Marchetti F, Triveri A, Pirota V, Torielli L, Collina S, Doria F, Freccero M, Colombo G. PMID: 34671733; PMCID: PMC8459323.

View in: PubMed Mentions: 1
Exploiting Folding and Degradation Machineries To Target Undruggable Proteins: What Can a Computational Approach Tell Us? ChemMedChem. 2021 05 18; 16(10):1593-1599. Serapian SA, Triveri A, Marchetti F, Castelli M, Colombo G. PMID: 33443306.

View in: PubMed Mentions: 2 Fields:
Che Chemistry Pha Pharmacology
Translation:Humans Cells