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Graham Timmins

Title(s)Visiting Professor, Political Science
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Neuronal Zinc Transporter ZnT3 Modulates Cerebral Ischemia-Induced Blood-Brain Barrier Disruption. Aging Dis. 2023 10 18; 15(6):2727-2741. Qi Z, Zhou X, Dong W, Timmins GS, Pan R, Shi W, Yuan S, Zhao Y, Ji X, Liu KJ. PMID: 37962463; PMCID: PMC11567248.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    2. Mammalian ATG8 proteins maintain autophagosomal membrane integrity through ESCRTs. EMBO J. 2023 07 17; 42(14):e112845. Javed R, Jain A, Duque T, Hendrix E, Paddar MA, Khan S, Claude-Taupin A, Jia J, Allers L, Wang F, Mudd M, Timmins G, Lidke K, Rusten TE, Akepati PR, He Y, Reggiori F, Eskelinen EL, Deretic V. PMID: 37272163; PMCID: PMC10350836.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    3. Mammalian hybrid prophagophore is a precursor to autophagosomes. Autophagy. 2023 Aug; 19(8):2391-2392. Kumar S, Javed R, Paddar MA, Eskelinen EL, Timmins GS, Deretic V. PMID: 36571474; PMCID: PMC10351457.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    4. Mammalian hybrid pre-autophagosomal structure HyPAS generates autophagosomes. Cell. 2021 11 24; 184(24):5950-5969.e22. Kumar S, Javed R, Mudd M, Pallikkuth S, Lidke KA, Jain A, Tangavelou K, Gudmundsson SR, Ye C, Rusten TE, Anonsen JH, Lystad AH, Claude-Taupin A, Simonsen A, Salemi M, Phinney B, Li J, Guo LW, Bradfute SB, Timmins GS, Eskelinen EL, Deretic V. PMID: 34741801; PMCID: PMC8616855.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    5. Rapamycin modulates pulmonary pathology in a murine model of Mycobacterium tuberculosis infection. Dis Model Mech. 2021 10 01; 14(10). Bhatt K, Bhagavathula M, Verma S, Timmins GS, Deretic VP, Ellner JJ, Salgame P. PMID: 34486033; PMCID: PMC8560501.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    6. Endogenous zinc protoporphyrin formation critically contributes to hemorrhagic stroke-induced brain damage. J Cereb Blood Flow Metab. 2021 12; 41(12):3232-3247. Pan R, Yu S, Zhang H, Timmins GS, Weaver J, Yang Y, Zhou X, Liu KJ. PMID: 34187233; PMCID: PMC8669275.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    7. Ambroxol and Ciprofloxacin Show Activity Against SARS-CoV2 in Vero E6 Cells at Clinically-Relevant Concentrations. bioRxiv. 2020 Aug 11. Bradfute SB, Ye C, Clarke EC, Kumar S, Timmins GS, Deretic V. PMID: 32817934; PMCID: PMC7430564.
      View in: PubMed   Mentions:
    8. AMPK is activated during lysosomal damage via a galectin-ubiquitin signal transduction system. Autophagy. 2020 08; 16(8):1550-1552. Jia J, Bissa B, Brecht L, Allers L, Choi SW, Gu Y, Zbinden M, Burge MR, Timmins G, Hallows K, Behrends C, Deretic V. PMID: 32597364; PMCID: PMC7469532.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    9. Azithromycin and ciprofloxacin have a chloroquine-like effect on respiratory epithelial cells. bioRxiv. 2020 Mar 31. Poschet JF, Perkett EA, Timmins GS, Deretic V. PMID: 32511331; PMCID: PMC7239066.
      View in: PubMed   Mentions: 4  
    10. AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System. Mol Cell. 2020 03 05; 77(5):951-969.e9. Jia J, Bissa B, Brecht L, Allers L, Choi SW, Gu Y, Zbinden M, Burge MR, Timmins G, Hallows K, Behrends C, Deretic V. PMID: 31995728; PMCID: PMC7785494.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    11. What are the challenges in commercial non-tuberculous mycobacteria (NTM) drug discovery and how should we move forward? Expert Opin Drug Discov. 2020 01; 15(1):7-9. Timmins GS. PMID: 31566439.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    12. Evidence-based obviousness for use in patent prosecution and review. Nat Biotechnol. 2019 09; 37(9):997-1000. Timmins GS. PMID: 31485044.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Potential for breath test diagnosis of urease positive pathogens in lung infections. J Breath Res. 2019 06 04; 13(3):032002. Bishai WR, Timmins GS. PMID: 31096193.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    14. Enhancement of lung levels of antibiotics by ambroxol and bromhexine. Expert Opin Drug Metab Toxicol. 2019 Mar; 15(3):213-218. Deretic V, Timmins GS. PMID: 30721101; PMCID: PMC6947664.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    15. Pharmacist perceptions of the New Mexico pharmacist-performed tuberculosis testing program. J Am Pharm Assoc (2003). 2018 Nov - Dec; 58(6):647-651. Logothetis SJ, Borrego ME, Roberts MH, Bachyrycz A, Timmins GS, Jakeman B. PMID: 30274884; PMCID: PMC8083186.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Ambroxol Induces Autophagy and Potentiates Rifampin Antimycobacterial Activity. Antimicrob Agents Chemother. 2018 09; 62(9). Choi SW, Gu Y, Peters RS, Salgame P, Ellner JJ, Timmins GS, Deretic V. PMID: 30012752; PMCID: PMC6125555.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    17. Normobaric Hyperoxia Reduces Blood Occludin Fragments in Rats and Patients With Acute Ischemic Stroke. Stroke. 2017 10; 48(10):2848-2854. Shi S, Qi Z, Ma Q, Pan R, Timmins GS, Zhao Y, Shi W, Zhang Y, Ji X, Liu KJ. PMID: 28931617; PMCID: PMC5659343.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimals
    18. Deuterated drugs; updates and obviousness analysis. Expert Opin Ther Pat. 2017 Dec; 27(12):1353-1361. Timmins GS. PMID: 28885861.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    19. Stool microbiome reveals diverse bacterial ureases as confounders of oral urea breath testing for Helicobacter pylori and Mycobacterium tuberculosis in Bamako, Mali. J Breath Res. 2016 08 17; 10(3):036012. Maiga M, Cohen K, Baya B, Srikrishna G, Siddiqui S, Sanogo M, Somboro AM, Diarra B, Diallo MH, Mazumdar V, Yoder C, Orsega S, Belson M, Kassambara H, Goita D, Murphy RL, Dao S, Polis M, Diallo S, Timmins GS, Dodd L, Earl AM, Bishai WR. PMID: 27532494; PMCID: PMC5046223.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    20. Stable isotope biomarker breath tests for human metabolic and infectious diseases: a review of recent patent literature. Expert Opin Ther Pat. 2016 Dec; 26(12):1393-1398. Timmins GS. PMID: 27467014; PMCID: PMC5160749.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    21. A Proof of Concept Study to Detect Urease Producing Bacteria in Lungs Using Aerosolized 13C-Urea. Pediatr Allergy Immunol Pulmonol. 2016 Jun 01; 29(2):68-73. Raissy HH, Timmins G, Davies L, Heynekamp T, Harkins M, Sharp ZD, Kelly HW. PMID: 27458537; PMCID: PMC4926200.
      View in: PubMed   Mentions: 3     Fields:    
    22. Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential. Nat Commun. 2015 Oct 27; 6:8620. Chauhan S, Ahmed Z, Bradfute SB, Arko-Mensah J, Mandell MA, Won Choi S, Kimura T, Blanchet F, Waller A, Mudd MH, Jiang S, Sklar L, Timmins GS, Maphis N, Bhaskar K, Piguet V, Deretic V. PMID: 26503418; PMCID: PMC4624223.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    23. Spray-Dried Multiscale Nano-biocomposites Containing Living Cells. ACS Nano. 2015 Jul 28; 9(7):6961-77. Johnson PE, Muttil P, MacKenzie D, Carnes EC, Pelowitz J, Mara NA, Mook WM, Jett SD, Dunphy DR, Timmins GS, Brinker CJ. PMID: 26083188.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    24. Detecting virulence and drug-resistance mycobacterial phenotypes in vivo. Trends Microbiol. 2015 Jun; 23(6):321-3. Timmins GS. PMID: 25800730; PMCID: PMC4458167.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    25. Autophagy Mediates Astrocyte Death During Zinc-Potentiated Ischemia--Reperfusion Injury. Biol Trace Elem Res. 2015 Jul; 166(1):89-95. Pan R, Timmins GS, Liu W, Liu KJ. PMID: 25758719; PMCID: PMC4470843.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    26. Immunologic manifestations of autophagy. J Clin Invest. 2015 Jan; 125(1):75-84. Deretic V, Kimura T, Timmins G, Moseley P, Chauhan S, Mandell M. PMID: 25654553; PMCID: PMC4350422.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimalsCells
    27. Rapid in vivo detection of isoniazid-sensitive Mycobacterium tuberculosis by breath test. Nat Commun. 2014 Sep 23; 5:4989. Choi SW, Maiga M, Maiga MC, Atudorei V, Sharp ZD, Bishai WR, Timmins GS. PMID: 25247851; PMCID: PMC4182730.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    28. Deuterated drugs: where are we now? Expert Opin Ther Pat. 2014 Oct; 24(10):1067-75. Timmins GS. PMID: 25069517; PMCID: PMC4579527.
      View in: PubMed   Mentions: 39     Fields:    
    29. In vitro and in vivo studies of a rapid and selective breath test for tuberculosis based upon mycobacterial CO dehydrogenase. mBio. 2014 Apr 15; 5(2):e00990. Maiga M, Choi SW, Atudorei V, Maiga MC, Sharp ZD, Bishai WR, Timmins GS. PMID: 24736224; PMCID: PMC3993857.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    30. Nox2 modification of LDL is essential for optimal apolipoprotein B-mediated control of agr type III Staphylococcus aureus quorum-sensing. PLoS Pathog. 2013 Feb; 9(2):e1003166. Hall PR, Elmore BO, Spang CH, Alexander SM, Manifold-Wheeler BC, Castleman MJ, Daly SM, Peterson MM, Sully EK, Femling JK, Otto M, Horswill AR, Timmins GS, Gresham HD. PMID: 23459693; PMCID: PMC3573103.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    31. Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation. Proc Natl Acad Sci U S A. 2012 Nov 13; 109(46):E3168-76. Castillo EF, Dekonenko A, Arko-Mensah J, Mandell MA, Dupont N, Jiang S, Delgado-Vargas M, Timmins GS, Bhattacharya D, Yang H, Hutt J, Lyons CR, Dobos KM, Deretic V. PMID: 23093667; PMCID: PMC3503152.
      View in: PubMed   Mentions: 278     Fields:    Translation:AnimalsCells
    32. Reporter phage and breath tests: emerging phenotypic assays for diagnosing active tuberculosis, antibiotic resistance, and treatment efficacy. J Infect Dis. 2011 Nov 15; 204 Suppl 4:S1142-50. Jain P, Thaler DS, Maiga M, Timmins GS, Bishai WR, Hatfull GF, Larsen MH, Jacobs WR. PMID: 21996696; PMCID: PMC3247800.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    33. 13[C]-urea breath test as a novel point-of-care biomarker for tuberculosis treatment and diagnosis. PLoS One. 2010 Aug 27; 5(8):e12451. Jassal MS, Nedeltchev GG, Lee JH, Choi SW, Atudorei V, Sharp ZD, Deretic V, Timmins GS, Bishai WR. PMID: 20805989; PMCID: PMC2929202.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCellsPHPublic Health
    34. Stable isotope-labeled excipients for drug product identification and counterfeit detection. Drug Dev Ind Pharm. 2011 Jan; 37(1):88-92. Felton LA, Shah PP, Sharp Z, Atudorei V, Timmins GS. PMID: 20560792.
      View in: PubMed   Mentions: 4     Fields:    
    35. Confinement-induced quorum sensing of individual Staphylococcus aureus bacteria. Nat Chem Biol. 2010 Jan; 6(1):41-5. Carnes EC, Lopez DM, Donegan NP, Cheung A, Gresham H, Timmins GS, Brinker CJ. PMID: 19935660; PMCID: PMC4201857.
      View in: PubMed   Mentions: 80     Fields:    Translation:Cells
    36. Direct visualization of mouse brain oxygen distribution by electron paramagnetic resonance imaging: application to focal cerebral ischemia. J Cereb Blood Flow Metab. 2009 Oct; 29(10):1695-703. Shen J, Sood R, Weaver J, Timmins GS, Schnell A, Miyake M, Kao JP, Rosen GM, Liu KJ. PMID: 19675560; PMCID: PMC3633216.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    37. Drugs: From Discovery to Approval:Drugs: From Discovery to Approval. Drug Dev Ind Pharm. 2009 May 26. Timmins GS. PMID: 19466899.
      View in: PubMed   Mentions:    Fields:    
    38. Low concentration of arsenite exacerbates UVR-induced DNA strand breaks by inhibiting PARP-1 activity. Toxicol Appl Pharmacol. 2008 Oct 01; 232(1):41-50. Qin XJ, Hudson LG, Liu W, Timmins GS, Liu KJ. PMID: 18619636; PMCID: PMC2584354.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    39. Mycobacterium tuberculosis prevents inflammasome activation. Cell Host Microbe. 2008 Apr 17; 3(4):224-32. Master SS, Rampini SK, Davis AS, Keller C, Ehlers S, Springer B, Timmins GS, Sander P, Deretic V. PMID: 18407066; PMCID: PMC3657562.
      View in: PubMed   Mentions: 191     Fields:    Translation:AnimalsCells
    40. Determination of wavelength-specific UV protection factors of sunscreens in intact skin by EPR measurement of UV-induced reactive melanin radical. Photochem Photobiol. 2007 Jul-Aug; 83(4):952-7. Lund L, Ley RD, Felton LA, Timmins GS. PMID: 17645669.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    41. Pharmacological modulation of cGMP levels by phosphodiesterase 5 inhibitors as a therapeutic strategy for treatment of respiratory pathology in cystic fibrosis. Am J Physiol Lung Cell Mol Physiol. 2007 Sep; 293(3):L712-9. Poschet JF, Timmins GS, Taylor-Cousar JL, Ornatowski W, Fazio J, Perkett E, Wilson KR, Yu HD, de Jonge HR, Deretic V. PMID: 17586695.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    42. Melanoma, long wavelength ultraviolet and sunscreens: controversies and potential resolutions. Pharmacol Ther. 2007 May; 114(2):198-207. Lund LP, Timmins GS. PMID: 17376535.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    43. Nitrosative stress inhibits production of the virulence factor alginate in mucoid Pseudomonas aeruginosa. Free Radic Res. 2007 Feb; 41(2):208-15. Wood SR, Firoved AM, Ornatowski W, Mai T, Deretic V, Timmins GS. PMID: 17364947.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    44. Mechanisms of action of isoniazid. Mol Microbiol. 2006 Dec; 62(5):1220-7. Timmins GS, Deretic V. PMID: 17074073.
      View in: PubMed   Mentions: 138     Fields:    Translation:Cells
    45. UV radiation induces delayed hyperrecombination associated with hypermutation in human cells. Mol Cell Biol. 2006 Aug; 26(16):6047-55. Durant ST, Paffett KS, Shrivastav M, Timmins GS, Morgan WF, Nickoloff JA. PMID: 16880516; PMCID: PMC1592811.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    46. Endosomal hyperacidification in cystic fibrosis is due to defective nitric oxide-cylic GMP signalling cascade. EMBO Rep. 2006 May; 7(5):553-9. Poschet JF, Fazio JA, Timmins GS, Ornatowski W, Perkett E, Delgado M, Deretic V. PMID: 16612392; PMCID: PMC1479567.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    47. Molecular and physiological effects of mycobacterial oxyR inactivation. J Bacteriol. 2006 Apr; 188(7):2674-80. Pagán-Ramos E, Master SS, Pritchett CL, Reimschuessel R, Trucksis M, Timmins GS, Deretic V. PMID: 16547055; PMCID: PMC1428386.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    48. UV causation of melanoma in Xiphophorus is dominated by melanin photosensitized oxidant production. Proc Natl Acad Sci U S A. 2006 Mar 14; 103(11):4111-5. Wood SR, Berwick M, Ley RD, Walter RB, Setlow RB, Timmins GS. PMID: 16537493; PMCID: PMC1449655.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimals
    49. A nondestructive technique to determine the rate of oxygen permeation into solid dosage forms. Pharm Dev Technol. 2006 Feb; 11(1):141-7. Felton LA, Timmins GS. PMID: 16544917.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    50. Measurement of S-nitrosothiols in extracellular fluids from healthy human volunteers and rheumatoid arthritis patients, using electron paramagnetic resonance spectrometry. Free Radic Biol Med. 2005 Oct 01; 39(7):937-48. Rocks SA, Davies CA, Hicks SL, Webb AJ, Klocke R, Timmins GS, Johnston A, Jawad AS, Blake DR, Benjamin N, Winyard PG. PMID: 16140213.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    51. Endothelin-1-mediated increase in reactive oxygen species and NADPH Oxidase activity in hearts of aryl hydrocarbon receptor (AhR) null mice. Toxicol Sci. 2005 Nov; 88(1):265-73. Lund AK, Peterson SL, Timmins GS, Walker MK. PMID: 16107552.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    52. Evaluation of spin trapping agents and trapping conditions for detection of cell-generated reactive oxygen species. Arch Biochem Biophys. 2005 May 01; 437(1):59-68. Shi H, Timmins G, Monske M, Burdick A, Kalyanaraman B, Liu Y, Clément JL, Burchiel S, Liu KJ. PMID: 15820217.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    53. Inactivation of a bacterial virulence pheromone by phagocyte-derived oxidants: new role for the NADPH oxidase in host defense. Proc Natl Acad Sci U S A. 2004 Sep 21; 101(38):13867-72. Rothfork JM, Timmins GS, Harris MN, Chen X, Lusis AJ, Otto M, Cheung AL, Gresham HD. PMID: 15353593; PMCID: PMC518845.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    54. Application of in vivo EPR in brain research: monitoring tissue oxygenation, blood flow, and oxidative stress. NMR Biomed. 2004 Aug; 17(5):327-34. Liu S, Timmins GS, Shi H, Gasparovic CM, Liu KJ. PMID: 15366032.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    55. Nitric oxide generated from isoniazid activation by KatG: source of nitric oxide and activity against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2004 Aug; 48(8):3006-9. Timmins GS, Master S, Rusnak F, Deretic V. PMID: 15273113; PMCID: PMC478481.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    56. Requirements for nitric oxide generation from isoniazid activation in vitro and inhibition of mycobacterial respiration in vivo. J Bacteriol. 2004 Aug; 186(16):5427-31. Timmins GS, Master S, Rusnak F, Deretic V. PMID: 15292144; PMCID: PMC490879.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    57. Microarray analysis and functional characterization of the nitrosative stress response in nonmucoid and mucoid Pseudomonas aeruginosa. J Bacteriol. 2004 Jun; 186(12):4046-50. Firoved AM, Wood SR, Ornatowski W, Deretic V, Timmins GS. PMID: 15175322; PMCID: PMC419947.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    58. Xanthine oxidase activates pro-matrix metalloproteinase-2 in cultured rat vascular smooth muscle cells through non-free radical mechanisms. Arch Biochem Biophys. 2004 Jun 01; 426(1):11-7. Liu W, Rosenberg GA, Shi H, Furuichi T, Timmins GS, Cunningham LA, Liu KJ. PMID: 15130778.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    59. Mycobacteria inhibit nitric oxide synthase recruitment to phagosomes during macrophage infection. Infect Immun. 2004 May; 72(5):2872-8. Miller BH, Fratti RA, Poschet JF, Timmins GS, Master SS, Burgos M, Marletta MA, Deretic V. PMID: 15102799; PMCID: PMC387846.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    60. Interstitial pO2 in ischemic penumbra and core are differentially affected following transient focal cerebral ischemia in rats. J Cereb Blood Flow Metab. 2004 Mar; 24(3):343-9. Liu S, Shi H, Liu W, Furuichi T, Timmins GS, Liu KJ. PMID: 15091115.
      View in: PubMed   Mentions: 83     Fields:    Translation:Animals
    61. Comparison of cross-linked polyethylene materials for orthopaedic applications. Clin Orthop Relat Res. 2003 Sep; (414):289-304. Collier JP, Currier BH, Kennedy FE, Currier JH, Timmins GS, Jackson SK, Brewer RL. PMID: 12966304.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    62. Determining the site of spin trapping of the equine myoglobin radical by combined use of EPR, electrophoretic purification, and mass spectrometry. Chem Res Toxicol. 2002 Dec; 15(12):1589-94. Harris MN, Burchiel SW, Winyard PG, Engen JR, Mobarak CD, Timmins GS. PMID: 12482241.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    63. Oxidative stress response genes in Mycobacterium tuberculosis: role of ahpC in resistance to peroxynitrite and stage-specific survival in macrophages. Microbiology (Reading). 2002 Oct; 148(Pt 10):3139-3144. Master SS, Springer B, Sander P, Boettger EC, Deretic V, Timmins GS. PMID: 12368447.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    64. Addition of candesartan to angiotensin converting enzyme inhibitor therapy in patients with chronic heart failure does not reduce levels of oxidative stress. Eur J Heart Fail. 2002 Mar; 4(2):193-9. Ellis GR, Nightingale AK, Blackman DJ, Anderson RA, Mumford C, Timmins G, Lang D, Jackson SK, Penney MD, Lewis MJ, Frenneaux MP, Morris-Thurgood J. PMID: 11959049.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    65. Detection and removal of contaminating hydroxylamines from the spin trap DEPMPO, and re-evaluation of its use to indicate nitrone radical cation formation and S(N)1 reactions. Free Radic Biol Med. 2002 Feb 01; 32(3):228-32. Jackson SK, Liu KJ, Liu M, Timmins GS. PMID: 11827748.
      View in: PubMed   Mentions: 5     Fields:    
    66. Firefly flashing is controlled by gating oxygen to light-emitting cells. J Exp Biol. 2001 Aug; 204(Pt 16):2795-801. Timmins GS, Robb FJ, Wilmot CM, Jackson SK, Swartz HM. PMID: 11683435.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    67. Characterization of the radical product formed from the reaction of nitric oxide with the spin trap 3,5-dibromo-4-nitrosobenzene sulfonate. Nitric Oxide. 2001 Apr; 5(2):116-27. Davies CA, Nielsen BR, Timmins G, Hamilton L, Brooker A, Guo R, Symons MC, Winyard PG. PMID: 11292361.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    68. The evolution of bioluminescent oxygen consumption as an ancient oxygen detoxification mechanism. J Mol Evol. 2001 Apr; 52(4):321-32. Timmins GS, Jackson SK, Swartz HM. PMID: 11343128.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    69. Applications of in vivo electron paramagnetic resonance (EPR) spectroscopy: measurements of pO2 and NO in endotoxin shock. Toxicol Lett. 2001 Mar 31; 120(1-3):253-7. Jackson SK, Madhani M, Thomas M, Timmins GS, James PE. PMID: 11323183.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    70. Direct determination of the kinetics of oxygen diffusion to the photocytes of a bioluminescent elaterid larva, measurement of gas- and aqueous-phase diffusional barriers and modelling of oxygen supply. J Exp Biol. 2000 Aug; 203(Pt 16):2479-84. Timmins GS, Bechara EJ, Swartz HM. PMID: 10903162.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    71. Measurement of oxygen partial pressure, its control during hypoxia and hyperoxia, and its effect upon light emission in a bioluminescent elaterid larva. J Exp Biol. 1999 Oct; 202(Pt 19):2631-8. Timmins GS, Penatti CA, Bechara EJ, Swartz HM. PMID: 10482722.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    72. Trapping of free radicals with direct in vivo EPR detection: a comparison of 5,5-dimethyl-1-pyrroline-N-oxide and 5-diethoxyphosphoryl-5-methyl-1-pyrroline-N-oxide as spin traps for HO* and SO4*-. Free Radic Biol Med. 1999 Aug; 27(3-4):329-33. Timmins GS, Liu KJ, Bechara EJ, Kotake Y, Swartz HM. PMID: 10468206.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    73. Photodynamically generated bovine serum albumin radicals: evidence for damage transfer and oxidation at cysteine and tryptophan residues. Free Radic Biol Med. 1998 Mar 15; 24(5):754-66. Silvester JA, Timmins GS, Davies MJ. PMID: 9586806.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    74. Protein hydroperoxides and carbonyl groups generated by porphyrin-induced photo-oxidation of bovine serum albumin. Arch Biochem Biophys. 1998 Feb 15; 350(2):249-58. Silvester JA, Timmins GS, Davies MJ. PMID: 9473299.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    75. A study of photochemically-generated protein radical spin adducts on bovine serum albumin: the detection of genuine spin-trapping and artefactual, non-radical addition in the same molecule. Redox Rep. 1997 Aug; 3(4):225-31. Silvester JA, Wei XD, Davies MJ, Timmins GS. PMID: 27415024.
      View in: PubMed   Mentions: 2     Fields:    
    76. Use of isotopically labelled spin-traps to determine definitively the presence or absence of non-radical addition artefacts in EPR spin-trapping systems. Redox Rep. 1997 Apr; 3(2):125-33. Timmins GS, Barlow GK, Silvester JA, Wei X, Whitwood AC. PMID: 27406887.
      View in: PubMed   Mentions: 4     Fields:    
    77. The synthesis and use of a (15)N and (2)H isotopically-labelled derivative of the spin-trap 3, 5-dibromo-4-nitrosobenzenesulphonic acid. Redox Rep. 1996 Dec; 2(6):407-10. Timmins GS, Wei X, Hawkins CL, Taylor RJ, Davies MJ. PMID: 27406676.
      View in: PubMed   Mentions:    Fields:    
    78. EPR studies on the effects of complexation of heme by hemopexin upon its reactions with organic peroxides. Free Radic Res. 1995 Dec; 23(6):559-69. Timmins GS, Davies MJ, Song DX, Muller-Eberhard U. PMID: 8574350.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    79. Detection of protein radicals formed by the photodynamic action of porphyrin sensitizers. Biochem Soc Trans. 1995 May; 23(2):261S. Silvester JA, Timmins GS, Davies MJ. PMID: 7672285.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    80. A study of the effects of complexation of heme by hemopexin upon its reactions with organic peroxides. Biochem Soc Trans. 1995 May; 23(2):244S. Timmins GS, Davies MJ, Muller-Eberhard U. PMID: 7672265.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    81. Conformational changes induced in bovine serum albumin by the photodynamic action of haematoporphyrin. J Photochem Photobiol B. 1994 Jul; 24(2):117-22. Timmins GS, Davies MJ. PMID: 7931850.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    82. An EPR spin trapping study of albumin protein radicals formed by the photodynamic action of haematoporphyrin. J Photochem Photobiol B. 1993 Dec; 21(2-3):167-73. Timmins GS, Davies MJ. PMID: 8301413.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    83. Free radical formation in isolated murine keratinocytes treated with organic peroxides and its modulation by antioxidants. Carcinogenesis. 1993 Aug; 14(8):1615-20. Timmins GS, Davies MJ. PMID: 8394781.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    84. Free radical formation in murine skin treated with tumour promoting organic peroxides. Carcinogenesis. 1993 Aug; 14(8):1499-503. Timmins GS, Davies MJ. PMID: 8394776.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
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