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George Somero

Title(s)Emeritus Professor, Marine Biology
SchoolVc-marine Sciences
Address9500 Gilman Drive #
La Jolla CA 92093
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    1. Mussel acclimatization to high, variable temperatures is lost slowly upon transfer to benign conditions. J Exp Biol. 2020 Jul 01; 223(Pt 13). Moyen NE, Somero GN, Denny MW. PMID: 32457061.
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    2. Introduction to the special issue: Comparative biology of cellular stress responses in animals. J Exp Zool A Ecol Integr Physiol. 2020 Jul; 333(6):345-349. Kültz D, Somero GN. PMID: 32588555.
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    3. Establishing typical values for hemocyte mortality in individual California mussels, Mytilus californianus. Fish Shellfish Immunol. 2020 May; 100:70-79. Moyen NE, Bump PA, Somero GN, Denny MW. PMID: 32135339.
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    4. The cellular stress response and temperature: Function, regulation, and evolution. J Exp Zool A Ecol Integr Physiol. 2020 Jul; 333(6):379-397. Somero GN. PMID: 31944627.
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    5. Impact of heating rate on cardiac thermal tolerance in the California mussel, Mytilus californianus. J Exp Biol. 2019 09 03; 222(Pt 17). Moyen NE, Somero GN, Denny MW. PMID: 31395674.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    6. Comparing mutagenesis and simulations as tools for identifying functionally important sequence changes for protein thermal adaptation. Proc Natl Acad Sci U S A. 2019 01 08; 116(2):679-688. Liao ML, Somero GN, Dong YW. PMID: 30584112.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    7. RNA thermosensors: how might animals exploit their regulatory potential? J Exp Biol. 2018 02 22; 221(Pt 4). Somero GN. PMID: 29472490.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    8. Structural flexibility and protein adaptation to temperature: Molecular dynamics analysis of malate dehydrogenases of marine molluscs. Proc Natl Acad Sci U S A. 2018 02 06; 115(6):1274-1279. Dong YW, Liao ML, Meng XL, Somero GN. PMID: 29358381.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    9. Thermal history and gape of individual Mytilus californianus correlate with oxidative damage and thermoprotective osmolytes. J Exp Biol. 2017 11 15; 220(Pt 22):4292-4304. Gleason LU, Miller LP, Winnikoff JR, Somero GN, Yancey PH, Bratz D, Dowd WW. PMID: 29141883.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    10. Heat-resistant cytosolic malate dehydrogenases (cMDHs) of thermophilic intertidal snails (genus Echinolittorina): protein underpinnings of tolerance to body temperatures reaching 55°C. J Exp Biol. 2017 06 01; 220(Pt 11):2066-2075. Liao ML, Zhang S, Zhang GY, Chu YM, Somero GN, Dong YW. PMID: 28566358.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    11. Untangling the roles of microclimate, behaviour and physiological polymorphism in governing vulnerability of intertidal snails to heat stress. Proc Biol Sci. 2017 May 17; 284(1854). Dong YW, Li XX, Choi FMP, Williams GA, Somero GN, Helmuth B. PMID: 28469014.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    12. Adaptations of protein structure and function to temperature: there is more than one way to 'skin a cat'. J Exp Biol. 2015 Jun; 218(Pt 12):1801-11. Fields PA, Dong Y, Meng X, Somero GN. PMID: 26085658.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    13. Proteomic analysis of cardiac response to thermal acclimation in the eurythermal goby fish Gillichthys mirabilis. J Exp Biol. 2015 May; 218(Pt 9):1359-72. Jayasundara N, Tomanek L, Dowd WW, Somero GN. PMID: 25954043.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    14. Temporal patterning of thermal acclimation: from behavior to membrane biophysics. J Exp Biol. 2015 Feb 01; 218(Pt 3):500. Somero G. PMID: 25653424.
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    15. Temporal patterning of thermal acclimation: from behavior to membrane biophysics. J Exp Biol. 2015 Jan 15; 218(Pt 2):167-9. Somero G. PMID: 25609779.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    16. Master of all trades: thermal acclimation and adaptation of cardiac function in a broadly distributed marine invasive species, the European green crab, Carcinus maenas. J Exp Biol. 2014 Apr 01; 217(Pt 7):1129-38. Tepolt CK, Somero GN. PMID: 24671964.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    17. Physiological plasticity of cardiorespiratory function in a eurythermal marine teleost, the longjaw mudsucker, Gillichthys mirabilis. J Exp Biol. 2013 Jun 01; 216(Pt 11):2111-21. Jayasundara N, Somero GN. PMID: 23678101.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    18. A 1950s classic of thermal adaptation to cold. J Exp Biol. 2013 May 15; 216(Pt 10):1759-61. Somero GN. PMID: 23785104.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    19. Thermal stress and cellular signaling processes in hemocytes of native (Mytilus californianus) and invasive (M. galloprovincialis) mussels: cell cycle regulation and DNA repair. Comp Biochem Physiol A Mol Integr Physiol. 2013 Jun; 165(2):159-68. Yao CL, Somero GN. PMID: 23454628.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    20. Behavior and survival of Mytilus congeners following episodes of elevated body temperature in air and seawater. J Exp Biol. 2013 Feb 01; 216(Pt 3):502-14. Dowd WW, Somero GN. PMID: 23038732.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    21. The impact of acute temperature stress on hemocytes of invasive and native mussels (Mytilus galloprovincialis and Mytilus californianus): DNA damage, membrane integrity, apoptosis and signaling pathways. J Exp Biol. 2012 Dec 15; 215(Pt 24):4267-77. Yao CL, Somero GN. PMID: 22972891.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    22. Functional determinants of temperature adaptation in enzymes of cold- versus warm-adapted mussels (Genus Mytilus). Mol Biol Evol. 2012 Oct; 29(10):3061-70. Lockwood BL, Somero GN. PMID: 22491035.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    23. The physiology of global change: linking patterns to mechanisms. Ann Rev Mar Sci. 2012; 4:39-61. Somero GN. PMID: 22457968.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsPHPublic Health
    24. Bruce D. Sidell (20 March 1948-8 February 2011). Comp Biochem Physiol C Toxicol Pharmacol. 2011 Nov; 154(4):437-9. Driedzic WR, Shick JM, Somero GN. PMID: 22010291.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    25. Bruce D. Sidell (20 March 1948-8 February 2011). Comp Biochem Physiol A Mol Integr Physiol. 2011 Nov; 160(3):440-2. Driedzic WR, Shick JM, Somero GN. PMID: 21980604.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Bruce D. Sidell (20 March 1948-8 February 2011). Comp Biochem Physiol B Biochem Mol Biol. 2011 Oct; 160(2-3):119-21. Driedzic WR, Shick JM, Somero GN. PMID: 21984995.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    27. Bruce D. Sidell. 20 March 1948 - 8 February 2011. J Exp Biol. 2011 Aug 01; 214(Pt 15):2453-4. Driedzic W, Shick JM, Somero GN. PMID: 21877336.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    28. Comparative physiology: a "crystal ball" for predicting consequences of global change. . 2011 Jul; 301(1):R1-14. Somero GN. PMID: 21430078.
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    29. Effects of thermal acclimation on transcriptional responses to acute heat stress in the eurythermal fish Gillichthys mirabilis (Cooper). . 2011 Jun; 300(6):R1373-83. Logan CA, Somero GN. PMID: 21411771.
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    30. Transcriptomic responses to salinity stress in invasive and native blue mussels (genus Mytilus). Mol Ecol. 2011 Feb; 20(3):517-29. Lockwood BL, Somero GN. PMID: 21199031.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    31. Transcriptomic responses to heat stress in invasive and native blue mussels (genus Mytilus): molecular correlates of invasive success. J Exp Biol. 2010 Oct 15; 213(Pt 20):3548-58. Lockwood BL, Sanders JG, Somero GN. PMID: 20889835.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    32. Phosphorylation events catalyzed by major cell signaling proteins differ in response to thermal and osmotic stress among native (Mytilus californianus and Mytilus trossulus) and invasive (Mytilus galloprovincialis) species of mussels. Physiol Biochem Zool. 2010 Nov-Dec; 83(6):984-96. Evans TG, Somero GN. PMID: 20946068.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    33. Transcriptional responses to thermal acclimation in the eurythermal fish Gillichthys mirabilis (Cooper 1864). . 2010 Sep; 299(3):R843-52. Logan CA, Somero GN. PMID: 20610827.
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    34. The physiology of climate change: how potentials for acclimatization and genetic adaptation will determine 'winners' and 'losers'. J Exp Biol. 2010 Mar 15; 213(6):912-20. Somero GN. PMID: 20190116.
      View in: PubMed   Mentions: 204     Fields:    Translation:AnimalsCells
    35. Heterologous hybridization to a complementary DNA microarray reveals the effect of thermal acclimation in the endothermic bluefin tuna (Thunnus orientalis). Mol Ecol. 2009 May; 18(10):2092-102. Castilho PC, Buckley BA, Somero G, Block BA. PMID: 19389180.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    36. Protein-protein interactions enable rapid adaptive response to osmotic stress in fish gills. Commun Integr Biol. 2009; 2(2):94-6. Evans TG, Somero GN. PMID: 19704899.
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    37. Temperature adaptation of cytosolic malate dehydrogenases of limpets (genus Lottia): differences in stability and function due to minor changes in sequence correlate with biogeographic and vertical distributions. J Exp Biol. 2009 Jan; 212(Pt 2):169-77. Dong Y, Somero GN. PMID: 19112135.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    38. A microarray-based transcriptomic time-course of hyper- and hypo-osmotic stress signaling events in the euryhaline fish Gillichthys mirabilis: osmosensors to effectors. J Exp Biol. 2008 Nov; 211(Pt 22):3636-49. Evans TG, Somero GN. PMID: 18978229.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    39. Rhythms of gene expression in a fluctuating intertidal environment. Curr Biol. 2008 Oct 14; 18(19):1501-7. Gracey AY, Chaney ML, Boomhower JP, Tyburczy WR, Connor K, Somero GN. PMID: 18848447.
      View in: PubMed   Mentions: 37     Fields:    Translation:Animals
    40. Heat-shock protein 70 (Hsp70) expression in four limpets of the genus Lottia: interspecific variation in constitutive and inducible synthesis correlates with in situ exposure to heat stress. Biol Bull. 2008 Oct; 215(2):173-81. Dong Y, Miller LP, Sanders JG, Somero GN. PMID: 18840778.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    41. Thermal limits and adaptation in marine Antarctic ectotherms: an integrative view. Philos Trans R Soc Lond B Biol Sci. 2007 Dec 29; 362(1488):2233-58. Pörtner HO, Peck L, Somero G. PMID: 17553776.
      View in: PubMed   Mentions: 44     Fields:    Translation:Animals
    42. Extreme anoxia tolerance in embryos of the annual killifish Austrofundulus limnaeus: insights from a metabolomics analysis. J Exp Biol. 2007 Jul; 210(Pt 13):2253-66. Podrabsky JE, Lopez JP, Fan TW, Higashi R, Somero GN. PMID: 17575031.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    43. Guest editors' introduction. J Exp Biol. 2007 May; 210(Pt 9):1491. Cossins A, Somero G. PMID: 17449813.
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    44. An inducible 70 kDa-class heat shock protein is constitutively expressed during early development and diapause in the annual killifish Austrofundulus limnaeus. Cell Stress Chaperones. 2007; 12(3):199-204. Podrabsky JE, Somero GN. PMID: 17915551.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    45. Biochemical adaptations of notothenioid fishes: comparisons between cold temperate South American and New Zealand species and Antarctic species. Comp Biochem Physiol A Mol Integr Physiol. 2007 Jul; 147(3):799-807. Petricorena ZL, Somero GN. PMID: 17293146.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    46. Following the heart: temperature and salinity effects on heart rate in native and invasive species of blue mussels (genus Mytilus). J Exp Biol. 2006 Jul; 209(Pt 13):2554-66. Braby CE, Somero GN. PMID: 16788038.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    47. The cellular response to heat stress in the goby Gillichthys mirabilis: a cDNA microarray and protein-level analysis. J Exp Biol. 2006 Jul; 209(Pt 14):2660-77. Buckley BA, Gracey AY, Somero GN. PMID: 16809457.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    48. Temperature sensitivities of cytosolic malate dehydrogenases from native and invasive species of marine mussels (genus Mytilus): sequence-function linkages and correlations with biogeographic distribution. J Exp Biol. 2006 Feb; 209(Pt 4):656-67. Fields PA, Rudomin EL, Somero GN. PMID: 16449560.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    49. Evolutionary and acclimation-induced variation in the thermal limits of heart function in congeneric marine snails (genus Tegula): implications for vertical zonation. Biol Bull. 2005 Apr; 208(2):138-44. Stenseng E, Braby CE, Somero GN. PMID: 15837963.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    50. Linking biogeography to physiology: Evolutionary and acclimatory adjustments of thermal limits. Front Zool. 2005 Jan 17; 2(1):1. Somero GN. PMID: 15679952.
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    51. Peter Hochachka: adventures in biochemical adaptation. Annu Rev Physiol. 2005; 67:25-37. Somero GN, Suarez RK. PMID: 15709951.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    52. Preface to Peter Hochachka memorial volume. Comp Biochem Physiol B Biochem Mol Biol. 2004 Nov; 139(3):311-5. Somero GN. PMID: 15544956.
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    53. Adaptation of enzymes to temperature: searching for basic "strategies". Comp Biochem Physiol B Biochem Mol Biol. 2004 Nov; 139(3):321-33. Somero GN. PMID: 15544958.
      View in: PubMed   Mentions: 55     Fields:    Translation:Animals
    54. Changes in gene expression associated with acclimation to constant temperatures and fluctuating daily temperatures in an annual killifish Austrofundulus limnaeus. J Exp Biol. 2004 Jun; 207(Pt 13):2237-54. Podrabsky JE, Somero GN. PMID: 15159429.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    55. Evolutionary convergence in adaptation of proteins to temperature: A4-lactate dehydrogenases of Pacific damselfishes (Chromis spp.). Mol Biol Evol. 2004 Feb; 21(2):314-20. Johns GC, Somero GN. PMID: 14660697.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    56. Protein adaptations to temperature and pressure: complementary roles of adaptive changes in amino acid sequence and internal milieu. Comp Biochem Physiol B Biochem Mol Biol. 2003 Dec; 136(4):577-91. Somero GN. PMID: 14662287.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    57. Influences of thermal acclimation and acute temperature change on the motility of epithelial wound-healing cells (keratocytes) of tropical, temperate and Antarctic fish. J Exp Biol. 2003 Dec; 206(Pt 24):4539-51. Ream RA, Theriot JA, Somero GN. PMID: 14610038.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    58. Local selection and latitudinal variation in a marine predator-prey interaction. Science. 2003 May 16; 300(5622):1135-7. Sanford E, Roth MS, Johns GC, Wares JP, Somero GN. PMID: 12750518.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    59. Base compositions of genes encoding alpha-actin and lactate dehydrogenase-A from differently adapted vertebrates show no temperature-adaptive variation in G + C content. Mol Biol Evol. 2003 Jan; 20(1):105-10. Ream RA, Johns GC, Somero GN. PMID: 12519912.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    60. Obituary: Peter W. Hochachka (1937-2002). Comp Biochem Physiol C Toxicol Pharmacol. 2002 Dec; 133(4):471-3. Somero GN. PMID: 12841218.
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    61. Thermal physiology and vertical zonation of intertidal animals: optima, limits, and costs of living. . 2002 Aug; 42(4):780-9. Somero GN. PMID: 21708776.
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    62. Temperature adaptation in Gillichthys (Teleost: Gobiidae) A(4)-lactate dehydrogenases: identical primary structures produce subtly different conformations. J Exp Biol. 2002 May; 205(Pt 9):1293-303. Fields PA, Kim YS, Carpenter JF, Somero GN. PMID: 11948206.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    63. Interspecific- and acclimation-induced variation in levels of heat-shock proteins 70 (hsp70) and 90 (hsp90) and heat-shock transcription factor-1 (HSF1) in congeneric marine snails (genus Tegula): implications for regulation of hsp gene expression. J Exp Biol. 2002 Mar; 205(Pt 5):677-85. Tomanek L, Somero GN. PMID: 11907057.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    64. Phylogenetic relationships and biochemical properties of the duplicated cytosolic and mitochondrial isoforms of malate dehydrogenase from a teleost fish, Sphyraena idiastes. J Mol Evol. 2002 Jan; 54(1):107-17. Lin JJ, Yang TH, Wahlstrand BD, Fields PA, Somero GN. PMID: 11734904.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    65. Intrinsic versus extrinsic stabilization of enzymes: the interaction of solutes and temperature on A4-lactate dehydrogenase orthologs from warm-adapted and cold-adapted marine fishes. Eur J Biochem. 2001 Aug; 268(16):4497-505. Fields PA, Wahlstrand BD, Somero GN. PMID: 11502210.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    66. Hypoxia-induced gene expression profiling in the euryoxic fish Gillichthys mirabilis. Proc Natl Acad Sci U S A. 2001 Feb 13; 98(4):1993-8. Gracey AY, Troll JV, Somero GN. PMID: 11172064.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    67. A comparative analysis of the evolutionary patterning and mechanistic bases of lactate dehydrogenase thermal stability in porcelain crabs, genus Petrolisthes. J Exp Biol. 2001 Feb; 204(Pt 4):767-76. Stillman JH, Somero GN. PMID: 11171359.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    68. Heat-shock protein expression is absent in the antarctic fish Trematomus bernacchii (family Nototheniidae). J Exp Biol. 2000 Aug; 203(Pt 15):2331-9. Hofmann GE, Buckley BA, Airaksinen S, Keen JE, Somero GN. PMID: 10887071.
      View in: PubMed   Mentions: 50     Fields:    Translation:Animals
    69. A comparative analysis of the upper thermal tolerance limits of eastern Pacific porcelain crabs, genus Petrolisthes: influences of latitude, vertical zonation, acclimation, and phylogeny. Physiol Biochem Zool. 2000 Mar-Apr; 73(2):200-8. Stillman JH, Somero GN. PMID: 10801398.
      View in: PubMed   Mentions: 47     Fields:    Translation:Animals
    70. Time course and magnitude of synthesis of heat-shock proteins in congeneric marine snails (Genus tegula) from different tidal heights. Physiol Biochem Zool. 2000 Mar-Apr; 73(2):249-56. Tomanek L, Somero GN. PMID: 10801403.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    71. Unity in diversity: a perspective on the methods, contributions, and future of comparative physiology. Annu Rev Physiol. 2000; 62:927-37. Somero GN. PMID: 10845117.
      View in: PubMed   Mentions: 4     Fields:    
    72. Hot spots in cold adaptation: localized increases in conformational flexibility in lactate dehydrogenase A4 orthologs of Antarctic notothenioid fishes. Proc Natl Acad Sci U S A. 1998 Sep 15; 95(19):11476-81. Fields PA, Somero GN. PMID: 9736762.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    73. Heat-Shock Protein Expression in Mytilus californianus: Acclimatization (Seasonal and Tidal-Height Comparisons) and Acclimation Effects. Biol Bull. 1997 Apr; 192(2):309-320. Roberts DA, Hofmann GE, Somero GN. PMID: 28581871.
      View in: PubMed   Mentions: 10     Fields:    
    74. Evolution of lactate dehydrogenase-A homologs of barracuda fishes (genus Sphyraena) from different thermal environments: differences in kinetic properties and thermal stability are due to amino acid substitutions outside the active site. Biochemistry. 1997 Mar 18; 36(11):3207-15. Holland LZ, McFall-Ngai M, Somero GN. PMID: 9115998.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    75. Serge Timasheff: the man with a genius for solutions in biology. Biophys J. 1996 Oct; 71(4):1985-93. Schellman JA, Somero GN. PMID: 8889172.
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    76. Activity of lactate dehydrogenase but not its concentration of messenger RNA increases with body size in barred sand bass, Paralabrax nebulifer (Teleostei). Biol Bull. 1996 Oct; 191(2):155-8. Yang TH, Somero GN. PMID: 8916541.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    77. Differences in protein patterns of gill epithelial cells of the fish Gillichthys mirabilis after osmotic and thermal acclimation. J Comp Physiol B. 1996; 166(2):88-100. Kültz D, Somero GN. PMID: 8766907.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    78. Ion transport in gills of the euryhaline fish Gillichthys mirabilis is facilitated by a phosphocreatine circuit. Am J Physiol. 1995 Apr; 268(4 Pt 2):R1003-12. Kültz D, Somero GN. PMID: 7733382.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    79. Proteins and temperature. Annu Rev Physiol. 1995; 57:43-68. Somero GN. PMID: 7778874.
      View in: PubMed   Mentions: 108     Fields:    Translation:AnimalsCells
    80. Effects of expected global climate change on marine faunas. Trends Ecol Evol. 1993 Oct; 8(10):361-7. Fields PA, Graham JB, Rosenblatt RH, Somero GN. PMID: 21236196.
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    81. Respiratory, Blood, and Heart Enzymatic Adaptations of Sebastolobus alascanus (Scorpaenidae; Teleostei) to the Oxygen Minimum Zone: A Comparative Study. Biol Bull. 1992 Dec; 183(3):490-499. Yang TH, Lai NC, Graham JB, Somero GN. PMID: 29300502.
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    82. Biochemical ecology of deep-sea animals. Experientia. 1992 Jun 15; 48(6):537-43. Somero GN. PMID: 1319350.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    83. The threshold induction temperature of the 90-kDa heat shock protein is subject to acclimatization in eurythermal goby fishes (genus Gillichthys). Proc Natl Acad Sci U S A. 1992 Apr 15; 89(8):3389-93. Dietz TJ, Somero GN. PMID: 1565632.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    84. Temperature- and concentration-dependence of compatibility of the organic osmolyte beta-dimethylsulfoniopropionate. Cryobiology. 1992 Feb; 29(1):118-24. Nishiguchi MK, Somero GN. PMID: 1295491.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    85. Adaptations to high hydrostatic pressure. Annu Rev Physiol. 1992; 54:557-77. Somero GN. PMID: 1314046.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    86. Pressure-Temperature Interactions on M4-Lactate Dehydrogenases From Hydrothermal Vent Fishes: Evidence for Adaptation to Elevated Temperatures by the Zoarcid Thermarces andersoni, but not by the Bythitid, Bythites hollisi. Biol Bull. 1990 Aug; 179(1):134-139. Dahlhoff E, Schneidemann S, Somero GN. PMID: 29314911.
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    87. Pressure adaptation of Na+/K+-ATPase in gills of marine teleosts. J Exp Biol. 1989 May; 143:475-92. Gibbs A, Somero GN. PMID: 2543729.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    88. Properties of the interaction between phosphofructokinase and actin. Arch Biochem Biophys. 1989 Feb 15; 269(1):284-94. Roberts SJ, Somero GN. PMID: 2521786.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    89. Regulation of binding of phosphofructokinase to myofibrils in the red and white muscle of the barred sand bass, Paralabrax nebulifer (Serranidae). J Exp Biol. 1988 Jul; 137:13-27. Roberts SJ, Lowery MS, Somero GN. PMID: 2974860.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    90. Binding of phosphofructokinase to filamentous actin. Biochemistry. 1987 Jun 16; 26(12):3437-42. Roberts SJ, Somero GN. PMID: 2958082.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    91. Protein adaptation and biogeography: Threshold effects on molecular evolution. Trends Ecol Evol. 1986 Nov; 1(5):124-7. Somero GN. PMID: 21227795.
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    92. Protons, osmolytes, and fitness of internal milieu for protein function. Am J Physiol. 1986 Aug; 251(2 Pt 2):R197-213. Somero GN. PMID: 3017133.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    93. Hydrogen Sulfide Oxidation Is Coupled to Oxidative Phosphorylation in Mitochondria of Solemya reidi. Science. 1986 Aug 01; 233(4763):563-6. Powell MA, Somero GN. PMID: 17820467.
      View in: PubMed   Mentions: 21     Fields:    
    94. Pressure effects on actin self-assembly: interspecific differences in the equilibrium and kinetics of the G to F transformation. Biochemistry. 1985 Feb 12; 24(4):852-60. Swezey RR, Somero GN. PMID: 3994993.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    95. Influence of osmolytes, thin filaments, and solubility state on elasmobranch phosphofructokinase in vitro. J Exp Zool. 1984 Aug; 231(2):297-302. Hand SC, Somero GN. PMID: 6237173.
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    96. Blood Components Prevent Sulfide Poisoning of Respiration of the Hydrothermal Vent Tube Worm Riftia pachyptila. Science. 1983 Jan 21; 219(4582):297-9. Powell MA, Somero GN. PMID: 17798280.
      View in: PubMed   Mentions: 1     Fields:    
    97. Environmental adaptation of proteins: strategies for the conservation of critical functional and structural traits. Comp Biochem Physiol A Comp Physiol. 1983; 76(3):621-33. Somero GN. PMID: 6139233.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    98. KINETIC AND ELECTROPHORETIC DIFFERENTIATION OF LACTATE DEHYDROGENASES OF TELEOST SPECIES-PAIRS FROM THE ATLANTIC AND PACIFIC COASTS OF PANAMA. Evolution. 1983 Jan; 37(1):30-37. Graves JE, Rosenblatt RH, Somero GN. PMID: 28568030.
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    99. Living with water stress: evolution of osmolyte systems. Science. 1982 Sep 24; 217(4566):1214-22. Yancey PH, Clark ME, Hand SC, Bowlus RD, Somero GN. PMID: 7112124.
      View in: PubMed   Mentions: 642     Fields:    Translation:AnimalsCells
    100. Polymerization thermodynamics and structural stabilities of skeletal muscle actins from vertebrates adapted to different temperatures and hydrostatic pressures. Biochemistry. 1982 Aug 31; 21(18):4496-503. Swezey RR, Somero GN. PMID: 7126554.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    101. Urea and methylamine effects on rabbit muscle phosphofructokinase. Catalytic stability and aggregation state as a function of pH and temperature. J Biol Chem. 1982 Jan 25; 257(2):734-41. Hand SC, Somero GN. PMID: 6459323.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    102. Acid-base regulation and phospholipid adaptations to temperature: time courses and physiological significance of modifying the milieu for protein function. Physiol Rev. 1982 Jan; 62(1):40-90. White FN, Somero G. PMID: 7034010.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    103. ELECTROPHORETIC AND FUNCTIONAL ENZYMIC EVOLUTION IN FOUR SPECIES OF EASTERN PACIFIC BARRACUDAS FROM DIFFERENT THERMAL ENVIRONMENTS. Evolution. 1982 Jan; 36(1):97-106. Graves JE, Somero GN. PMID: 28581099.
      View in: PubMed   Mentions: 7     Fields:    
    104. Effects of anions on the activation thermodynamics and fluorescence emission spectrum of alkaline phosphatase: evidence for enzyme hydration changes during catalysis. Biochemistry. 1979 Nov 27; 18(24):5322-32. Greaney GS, Somero GN. PMID: 518838.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    105. Inefficient lactate dehydrogenases of deep-sea fishes. Nature. 1979 Nov 01; 282(5734):100-2. Somero GN, Siebenaller JF. PMID: 503183.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    106. Counteraction of urea destabilization of protein structure by methylamine osmoregulatory compounds of elasmobranch fishes. Biochem J. 1979 Nov 01; 183(2):317-23. Yancey PH, Somero GN. PMID: 534499.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    107. Solute compatibility with enzyme function and structure: rationales for the selection of osmotic agents and end-products of anaerobic metabolism in marine invertebrates. J Exp Zool. 1979 May; 208(2):137-51. Bowlus RD, Somero GN. PMID: 469480.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    108. Pressure-adaptive differences in lactate dehydrogenases of congeneric fishes living at different depths. Science. 1978 Jul 21; 201(4352):255-7. Siebenaller J, Somero GN. PMID: 208149.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    109. Protein water binding ability correlates with cellular osmolarity. Experientia. 1978 Mar 15; 34(3):314-5. Low PS, Hoffmann KH, Swezey R, Somero GN. PMID: 631253.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    110. Neutral salt effects on the velocity and activation volume of the lactate dehydrogenase reaction: evidence for enzyme hydration changes during catalysis. Arch Biochem Biophys. 1977 Jun; 181(2):438-46. Somero GN, Neubauer M, Low PS. PMID: 900931.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    111. Enzyme hydration may explain catalytic efficiency differences among lactate dehydrogenase homologues. Nature. 1977 Mar 17; 266(5599):276-8. Somero GN, Low PS. PMID: 846575.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    112. Lead accumulation rates in tissues of the estuarine teleost fish, Gillichthys mirabilis: salinity and temperature effects. Arch Environ Contam Toxicol. 1977; 6(2-3):337-48. Somero GN, Chow TJ, Yancey PH, Snyder CB. PMID: 901012.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    113. Lead effects on tissue and whole organism respiration of the estuarine teleost fish, Gillichthys mirabilis. Arch Environ Contam Toxicol. 1977; 6(2-3):349-54. Somero GN, Yancey PH, Chow TJ, Snyder CB. PMID: 901013.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    114. Adaptation of muscle pyruvate kinases to environmental temperatures and pressures. J Exp Zool. 1976 Oct; 198(1):1-11. Low PS, Somero GN. PMID: 824400.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    115. Temperature: a "shaping force' in protein evolution. Biochem Soc Symp. 1976; (41):33-42. Somero GN, Low PS. PMID: 788719.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    116. Temperature as a selective factor in protein evolution: the adaptational strategy of "compromise". J Exp Zool. 1975 Oct; 194(1):175-88. Somero GN. PMID: 1104753.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    117. Pressure effects on enzyme structure and function in vitro and under simulated in vivo conditions. Comp Biochem Physiol B. 1975 Sep 15; 52(1):67-74. Low PS, Somero GN. PMID: 1183178.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    118. Protein hydration changes during catalysis: a new mechanism of enzymic rate-enhancement and ion activation/inhibition of catalysis. Proc Natl Acad Sci U S A. 1975 Sep; 72(9):3305-9. Low PS, Somero GN. PMID: 1059113.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    119. Activation volumes in enzymic catalysis: their sources and modification by low-molecular-weight solutes. Proc Natl Acad Sci U S A. 1975 Aug; 72(8):3014-8. Low PS, Somero GN. PMID: 1059089.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    120. Temperature adaptation of enzymes: a proposed molecular basis for the different catalytic efficiencies of enzymes from ectotherms and endotherms. Comp Biochem Physiol B. 1974 Oct 15; 49(2):307-12. Low PS, Somero GN. PMID: 4420155.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    121. Genetic variation in marine fishes as a test of the niche-variation hypothesis. Nature. 1974 Jun 14; 249(458):670-2. Somero GN, Soulé M. PMID: 4833808.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    122. Temperature and rates of protein degradation in the fish Gillichthys mirabilis. Comp Biochem Physiol B. 1973 Nov 15; 46(3):463-74. Somero GN, Doyle D. PMID: 4754763.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    123. Temperature adaptation of enzymes: roles of the free energy, the enthalpy, and the entropy of activation. Proc Natl Acad Sci U S A. 1973 Feb; 70(2):430-2. Low PS, Bada JL, Somero GN. PMID: 4510286.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    124. Thermal modulation of pyruvate metabolism in the fish Gillichthys mirabilis: the role of lactate dehydrogenases. Comp Biochem Physiol B. 1973 Jan 15; 44(1):205-9. Somero GN. PMID: 4683999.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    125. Pyruvate kinase variants of the Alaskan king-crab. Evidence for a temperature-dependent interconversion between two forms having distinct and adaptive kinetic properties. Biochem J. 1969 Sep; 114(2):237-41. Somero GN. PMID: 5810080.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    126. Isoenzymes and short-term temperature compensation in poikilotherms: activation of lactate dehydrogenase isoenzymes by temperature decreases. Nature. 1969 Jul 12; 223(5202):194-5. Somero GN, Hochachka PW. PMID: 5791732.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    127. The adaptation of enzymes to temperature. Comp Biochem Physiol. 1968 Dec; 27(3):659-68. Hochachka PW, Somero GN. PMID: 5710275.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    128. The effect of temperature on catalytic and regulatory functions of pyruvate kinases of the rainbow trout and the antarctic fish Trematomus bernacchii. Biochem J. 1968 Dec; 110(3):395-400. Somero GN, Hochachka PW. PMID: 5701664.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    129. Temperature tolerance of some Antarctic fishes. Science. 1967 Apr 14; 156(3772):257-8. Somero GN, DeVries AL. PMID: 6021046.
      View in: PubMed   Mentions: 42     Fields:    Translation:Animals
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