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A highly sensitive genetically encoded red cAMP sensor for multiplex imaging in vivo. Nat Commun. 2026 May 25; 17(1).
Wang L, Li L, Li X, Guo L, Luo B, Han Y, Fang S, Wang S, Shao R, Chen J, Stehle D, Zhang J, Mu Y, Zhu C, Du Y, Zhong H, Li Y, Chu J. PMID: 42185274.
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Single-cell analysis identifies the CNP/GC-B/cGMP axis as marker and regulator of modulated VSMCs in atherosclerosis. Nat Commun. 2025 Jan 15; 16(1):429.
Lehners M, Schmidt H, Zaldivia MTK, Stehle D, Krämer M, Peter A, Adler J, Lukowski R, Feil S, Feil R. PMID: 39814746; PMCID: PMC11735800.
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Inhibition of Phosphodiesterase 10A Alleviates Pain-like Behavior in Mice. Anesthesiology. 2025 Feb 01; 142(2):332-348.
Gross T, Stehle D, Nagel C, Zhou F, Duman E, Hernandez-Olmos V, Sinderwald R, Gerninghaus H, Petersen J, Feil S, Kallenborn-Gerhardt W, Lu R, Metzner K, Feil R, Proschak E, Schmidtko A. PMID: 39503623.
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Heterogeneity of cGMP signalling in tumour cells and the tumour microenvironment: Challenges and chances for cancer pharmacology and therapeutics. Pharmacol Ther. 2023 02; 242:108337.
Stehle D, Barresi M, Schulz J, Feil R. PMID: 36623589.
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9 Fields:
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Optogenetic manipulation of cyclic guanosine monophosphate to probe phosphodiesterase activities in megakaryocytes. Open Biol. 2022 08; 12(8):220058.
Zhang Y, Benz P, Stehle D, Yang S, Kurz H, Feil S, Nagel G, Feil R, Gao S, Bender M. PMID: 35975649; PMCID: PMC9382455.
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Novel soluble guanylyl cyclase activators increase glomerular cGMP, induce vasodilation and improve blood flow in the murine kidney. Br J Pharmacol. 2022 06; 179(11):2476-2489.
Stehle D, Xu MZ, Schomber T, Hahn MG, Schweda F, Feil S, Kraehling JR, Eitner F, Patzak A, Sandner P, Feil R, Bénardeau A. PMID: 34096053; PMCID: PMC9292672.
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23 Fields:
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Visualising and understanding cGMP signals in the cardiovascular system. Br J Pharmacol. 2022 06; 179(11):2394-2412.
Feil R, Lehners M, Stehle D, Feil S. PMID: 33880767.
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13 Fields:
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Amelanotic B16-F10 Melanoma Compatible with Advanced Three-Dimensional Imaging Modalities. J Invest Dermatol. 2021 08; 141(8):2090-2094.e6.
Tikoo S, Jain R, Tomasetig F, On K, Martinez B, Heu C, Stehle D, Obeidy P, Guo D, Vincent JN, Cook AJL, Roediger B, Feil R, Whan RM, Weninger W. PMID: 33675788.
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5 Fields:
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Contribution of BH3-domain and Transmembrane-domain to the Activity and Interaction of the Pore-forming Bcl-2 Proteins Bok, Bak, and Bax. Sci Rep. 2018 08 20; 8(1):12434.
Stehle D, Grimm M, Einsele-Scholz S, Ladwig F, Johänning J, Fischer G, Gillissen B, Schulze-Osthoff K, Essmann F. PMID: 30127460; PMCID: PMC6102298.
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13 Fields:
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Bok is a genuine multi-BH-domain protein that triggers apoptosis in the absence of Bax and Bak. J Cell Sci. 2016 08 01; 129(15):3054.
Einsele-Scholz S, Malmsheimer S, Bertram K, Stehle D, Johänning J, Manz M, Daniel PT, Gillissen BF, Schulze-Osthoff K, Essmann F. PMID: 27505430.
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Bok is a genuine multi-BH-domain protein that triggers apoptosis in the absence of Bax and Bak. J Cell Sci. 2016 06 01; 129(11):2213-23.
Einsele-Scholz S, Malmsheimer S, Bertram K, Stehle D, Johänning J, Manz M, Daniel PT, Gillissen BF, Schulze-Osthoff K, Essmann F. PMID: 27076518.
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28 Fields:
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