Humans homozygous for rare or common hypomorphic IL23R variants are prone to tuberculosis. J Exp Med. 2026 Aug 03; 223(8).
Olguín Calderón D, Kilpatrick LE, Conil C, Philippot Q, Ogishi M, Vellutini J, Han JE, Keating N, Li H, Rao G, Bohlen J, Lay CS, Platt S, Kerner G, Feredj E, Peel JN, Momenilandi M, Seeleuthner Y, Lainé C, Soudée C, Leloup C, Debuisson C, Lanternier F, Bitoun S, Pavy S, Mariette X, Rafik A, Skhoun H, El Ouazzani H, Abderahmani-Ghorfi I, El-Baghdadi J, Baena A, Tejada-Giraldo M, Barrera LF, Arias AA, Fabio G, Carrabba M, Emiroglu M, Bezrodnik L, El Zein L, Hammoud H, Gregersen PK, Terrier B, Leon Lopez R, Touzet M, Pestre V, Pasquet M, Rogge L, Fayon M, Galode F, Jeziorski E, Duffy D, Quintana-Murci L, Patin E, Cunningham-Rundles C, Meyts I, Zhang SY, Zhang Q, Jouanguy E, Boisson B, Rosain J, Béziat V, Shahrooei M, Mahdaviani SA, Rezaei N, Parvaneh N, Chavoshzadeh Z, Yazdanpanah N, Aladjidi N, Noguera-Julian A, Esteve-Solé A, Alsina L, Mansouri D, Keles S, Ortakoylu MG, Aygun D, Yucel E, Kiykim A, Camcioglu Y, Ma CS, Tangye SG, Zhang P, Abel L, Craggs PD, Casanova JL, Cobat A, Puel A, Bustamante J, Hill SJ, Boisson-Dupuis S. PMID: 42424313.
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Expanded T cell clones with lymphoma driver somatic mutations accumulate in refractory celiac disease. Sci Transl Med. 2025 May 14; 17(798):eadp6812.
Singh M, Louie RHY, Samir J, Field MA, Milthorpe C, Adikari T, Mackie J, Roper E, Faulks M, Jackson KJL, Calcino A, Hardy MY, Blombery P, Amos TG, Deveson IW, Wende HV, Floor SN, Read SA, Shek D, Guerin A, Ma CS, Tangye SG, Di Sabatino A, Lenti MV, Pasini A, Ciccocioppo R, Ahlenstiel G, Suan D, Tye-Din JA, Goodnow CC, Luciani F. PMID: 40367192.
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STAT5B restrains human B-cell differentiation to maintain humoral immune homeostasis. J Allergy Clin Immunol. 2022 10; 150(4):931-946.
Pelham SJ, Caldirola MS, Avery DT, Mackie J, Rao G, Gothe F, Peters TJ, Guerin A, Neumann D, Vokurkova D, Hwa V, Zhang W, Lyu SC, Chang I, Manohar M, Nadeau KC, Gaillard MI, Bezrodnik L, Iotova V, Zwirner NW, Gutierrez M, Al-Herz W, Goodnow CC, Vargas-Hernández A, Forbes Satter LR, Hambleton S, Deenick EK, Ma CS, Tangye SG. PMID: 35469842.
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