Ace George Santiago

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School	Vc-academic Affairs
Address	9500 Gilman Drive # La Jolla CA 92093
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Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

AuxB interacts directly with GpsB and PknB to coordinate cell envelope processes that contribute to intrinsic antibiotic resistance in Staphylococcus aureus. mBio. 2025 Oct 08; 16(10):e0185825. Sisley TA, Park Y, Santiago AG, Beroual W, Sobolewski IA, Lee W, Paulo JA, Walker S. PMID: 40852988; PMCID: PMC12505970.

View in: PubMed Mentions: Fields:
Mic Microbiology
Conformation-gated binding underlies kinetic asymmetry and negative cooperativity in ATP:cob(I)alamin adenosyltransferase. Cell Rep Phys Sci. 2025 Aug 20; 6(8). Yan G, Pan M, Keller AM, Santiago AG, Lofgren M, Banerjee R, Chen P, Chen TY. PMID: 40950835; PMCID: PMC12431680.

View in: PubMed Mentions:
Conformation-gated binding drives negative cooperativity in ATP:cob(I)alamin Adenosyltransferase for optimized cobalamin handling. bioRxiv. 2025 Jan 10. Yan G, Pan M, Keller AM, Santiago AG, Lofgren M, Banerjee R, Chen P, Chen TY. PMID: 39829891; PMCID: PMC11741278.

View in: PubMed Mentions:
Memory effects of transcription regulator-DNA interactions in bacteria. Proc Natl Acad Sci U S A. 2024 Oct 08; 121(41):e2407647121. Jung W, Chen TY, Santiago AG, Chen P. PMID: 39361642; PMCID: PMC11474097.

View in: PubMed Mentions: Fields:
Sci Science
Translation:Cells
The length of lipoteichoic acid polymers controls Staphylococcus aureus cell size and envelope integrity. J Bacteriol. 2020 Jun 01. Hesser AR, Matano LM, Vickery CR, Wood BM, Santiago AG, Morris HG, Do T, Losick R, Walker S. PMID: 32482719; PMCID: PMC8404710.

View in: PubMed Mentions: 33 Fields:
Bac Bacteriology
Metal-induced sensor mobilization turns on affinity to activate regulator for metal detoxification in live bacteria. Proc Natl Acad Sci U S A. 2020 06 16; 117(24):13248-13255. Fu B, Sengupta K, Genova LA, Santiago AG, Jung W, Krzeminski L, Chakraborty UK, Zhang W, Chen P. PMID: 32467170; PMCID: PMC7306728.

View in: PubMed Mentions: 11 Fields:
Sci Science
Translation:Cells
Staphylococcus aureus cell growth and division are regulated by an amidase that trims peptides from uncrosslinked peptidoglycan. Nat Microbiol. 2020 02; 5(2):291-303. Do T, Schaefer K, Santiago AG, Coe KA, Fernandes PB, Kahne D, Pinho MG, Walker S. PMID: 31932712; PMCID: PMC7046134.

View in: PubMed Mentions: 35 Fields:
Mic Microbiology Par Parasitology Vir Virology
Translation:Cells
Mechanical stress compromises multicomponent efflux complexes in bacteria. Proc Natl Acad Sci U S A. 2019 12 17; 116(51):25462-25467. Genova LA, Roberts MF, Wong YC, Harper CE, Santiago AG, Fu B, Srivastava A, Jung W, Wang LM, Krzeminski L, Mao X, Sun X, Hui CY, Chen P, Hernandez CJ. PMID: 31772020; PMCID: PMC6925999.

View in: PubMed Mentions: 15 Fields:
Sci Science
Translation:Cells
Adaptor protein mediates dynamic pump assembly for bacterial metal efflux. Proc Natl Acad Sci U S A. 2017 06 27; 114(26):6694-6699. Santiago AG, Chen TY, Genova LA, Jung W, George Thompson AM, McEvoy MM, Chen P. PMID: 28607072; PMCID: PMC5495265.

View in: PubMed Mentions: 20 Fields:
Sci Science
Translation:Cells
Single-molecule dynamics of the molecular chaperone trigger factor in living cells. Mol Microbiol. 2016 12; 102(6):992-1003. Yang F, Chen TY, Krzeminski L, Santiago AG, Jung W, Chen P. PMID: 27626893; PMCID: PMC5161668.

View in: PubMed Mentions: 10 Fields:
Mic Microbiology Mol Molecular Biology
Translation:Cells
Quantifying Multistate Cytoplasmic Molecular Diffusion in Bacterial Cells via Inverse Transform of Confined Displacement Distribution. J Phys Chem B. 2015 Nov 12; 119(45):14451-9. Chen TY, Jung W, Santiago AG, Yang F, Krzeminski L, Chen P. PMID: 26491971; PMCID: PMC4645974.

View in: PubMed Mentions: 10 Fields:
Che Chemistry
Translation:Cells
Metalloregulator CueR biases RNA polymerase's kinetic sampling of dead-end or open complex to repress or activate transcription. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):13467-72. Martell DJ, Joshi CP, Gaballa A, Santiago AG, Chen TY, Jung W, Helmann JD, Chen P. PMID: 26483469; PMCID: PMC4640755.

View in: PubMed Mentions: 19 Fields:
Sci Science
Translation:Cells
Concentration- and chromosome-organization-dependent regulator unbinding from DNA for transcription regulation in living cells. Nat Commun. 2015 Jul 06; 6:7445. Chen TY, Santiago AG, Jung W, Krzeminski L, Yang F, Martell DJ, Helmann JD, Chen P. PMID: 26145755; PMCID: PMC4507017.

View in: PubMed Mentions: 62 Fields:
Bio Biology Sci Science
Translation:Cells
Single-molecule dynamics and mechanisms of metalloregulators and metallochaperones. Biochemistry. 2013 Oct 15; 52(41):7170-83. Chen P, Keller AM, Joshi CP, Martell DJ, Andoy NM, Benítez JJ, Chen TY, Santiago AG, Yang F. PMID: 24053279; PMCID: PMC3830456.

View in: PubMed Mentions: 9 Fields:
Bio Biochemistry
Translation:Humans Animals Cells