Ziwei Huang

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Title(s)	Adjunct Professor, Medicine
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
vCard	Download vCard

Research

research activities and funding

NOVEL INHIBITORS OF THE HIV GP120-CD4 INTERACTION
NIH R21AI045414Sep 30, 1999 - Sep 29, 2001
Role: Principal Investigator

BIOLOGIC &CLINICAL PROPERTIES OF CD4 STRUCTURAL ANALOGS
NIH P01CA077401Apr 1, 1999 - Mar 31, 2004
Role: Co-Investigator

Structures and Interactions of Chemokine Receptors
NIH R01GM057761May 1, 1998 - Apr 30, 2018
Role: Principal Investigator

IMMUNOLOGICAL APPROACHES FOR ALLERGIC DISEASE
NIH R21AI042936May 1, 1998 - Apr 30, 2000
Role: Principal Investigator

CD4 PEPTIDES AND PEPTIDOMIMETICS AS INHIBITORS OF MS
NIH R29AI040081Jul 1, 1996 - Jun 30, 2002
Role: Principal Investigator

A Synchroton Radiation Structural Biology Resource
NIH P41RR001209Mar 1, 1980 - Feb 28, 2015
Role: Co-Investigator

Laboratory for Fluorescence Dynamics
NIH P41RR003155Jun 30, 2016
Role: Co-Investigator

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Synergistic inhibition of hepatitis C virus infection by a novel microtubule inhibitor in combination with daclatasvir. Biochem Biophys Rep. 2022 Jul; 30:101283. Zhang H, Zhang XQ, Huang LS, Fang X, Khan M, Xu Y, An J, Schooley RT, Huang Z. PMID: 35647321; PMCID: PMC9136107.

View in: PubMed Mentions:
Trends in application of advancing computational approaches in GPCR ligand discovery. Exp Biol Med (Maywood). 2021 05; 246(9):1011-1024. Zhu S, Wu M, Huang Z, An J. PMID: 33641446; PMCID: PMC8113737.

View in: PubMed Mentions: 3 Fields:
Bio Biology Med Medicine (General)Phy Physiology
Translation:Humans
Chemical mutagenesis of a GPCR ligand: Detoxifying "inflammo-attraction" to direct therapeutic stem cell migration. Proc Natl Acad Sci U S A. 2020 12 08; 117(49):31177-31188. Lee JP, Zhang R, Yan M, Duggineni S, Wakeman DR, Niles WL, Feng Y, Chen J, Hamblin MH, Han EB, Gonzalez R, Fang X, Zhu Y, Wang J, Xu Y, Wenger DA, Seyfried TN, An J, Sidman RL, Huang Z, Snyder EY. PMID: 33219123; PMCID: PMC7733796.

View in: PubMed Mentions: 9 Fields:
Sci Science
Translation:Humans Cells
Discoveries and developments of CXCR4-targeted HIV-1 entry inhibitors. Exp Biol Med (Maywood). 2020 03; 245(5):477-485. Zhang C, Zhu R, Cao Q, Yang X, Huang Z, An J. PMID: 32019336; PMCID: PMC7082890.

View in: PubMed Mentions: 12 Fields:
Bio Biology Med Medicine (General)Phy Physiology
Translation:Humans Cells
Pharmacokinetics of a novel microtubule inhibitor mHA11 in rats. Chem Biol Interact. 2019 Aug 01; 308:235-243. Yang S, Zhu Y, Fang X, Xu Y, Huang Y, An J, Huang Z. PMID: 31145889.

View in: PubMed Mentions: Fields:
Bio Biochemistry Pha Pharmacology
Translation:Humans Animals Cells
The chemical biology of apoptosis: Revisited after 17 years. Eur J Med Chem. 2019 Sep 01; 177:63-75. Yang S, Mao Y, Zhang H, Xu Y, An J, Huang Z. PMID: 31129454.

View in: PubMed Mentions: 12 Fields:
Che Chemistry
Translation:Humans Animals Cells
Discovery and Computational Analyses of Novel Small Molecule Zika Virus Inhibitors. Molecules. 2019 Apr 13; 24(8). Zhu S, Zhang C, Huang LS, Zhang XQ, Xu Y, Fang X, Zhou J, Wu M, Schooley RT, Huang Z, An J. PMID: 31013906; PMCID: PMC6514826.

View in: PubMed Mentions: 5 Fields:
Bio Biology
Translation:Humans Animals Cells
High affinity CXCR4 inhibitors generated by linking low affinity peptides. Eur J Med Chem. 2019 Jun 15; 172:174-185. Zhang C, Huang LS, Zhu R, Meng Q, Zhu S, Xu Y, Zhang H, Fang X, Zhang X, Zhou J, Schooley RT, Yang X, Huang Z, An J. PMID: 30978562; PMCID: PMC6677133.

View in: PubMed Mentions: 3 Fields:
Che Chemistry
Translation:Humans Cells
Virtual Screening, Biological Evaluation, and 3D-QSAR Studies of New HIV-1 Entry Inhibitors That Function via the CD4 Primary Receptor. Molecules. 2018 Nov 20; 23(11). Zhang C, Zhang H, Huang LS, Zhu S, Xu Y, Zhang XQ, Schooley RT, Yang X, Huang Z, An J. PMID: 30463393; PMCID: PMC6278378.

View in: PubMed Mentions: 2 Fields:
Bio Biology
Translation:Humans Cells
LC-MS/MS assay for the determination of a novel D-peptide antagonist of CXCR4 in rat plasma and its application to a preclinical pharmacokinetic study. J Pharm Biomed Anal. 2018 Nov 30; 161:159-167. Zhu Y, Yang S, Wang J, Mao Y, Xu Y, An J, Huang Z. PMID: 30165332; PMCID: PMC10264084.

View in: PubMed Mentions: 3 Fields:
Bio Biochemistry Pha Pharmacology
Translation:Animals
Design, synthesis, and biological characterization of novel PEG-linked dimeric modulators for CXCR4. Bioorg Med Chem. 2016 11 01; 24(21):5393-5399. Yang Y, Gao M, Zhang Q, Zhang C, Yang X, Huang Z, An J. PMID: 27658790; PMCID: PMC5498155.

View in: PubMed Mentions: 7 Fields:
Bio Biochemistry Che Chemistry
Translation:Humans Cells