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Xiaohua Huang

Title(s)Associate Professor, Bioengineering
SchoolAcademic Aff
Address9500 Gilman Drive #0412
La Jolla CA 92093
Phone858-822-2155
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    Collapse Research 
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    Technology for measuring telomere length of individual chromosomes of single cancer cells
    NIH/NCI R21CA223727Mar 1, 2019 - Feb 28, 2021
    Role: Principal Investigator
    Nanopore Direct Single-Molecule Protein Sequencing
    NIH/NIGMS R01GM126013Aug 1, 2018 - Apr 30, 2022
    Role: Principal Investigator
    Single-stranded sequencing using microfluidic reactors (SISSOR)
    NIH/NHGRI R01HG007836Aug 1, 2014 - May 31, 2018
    Role: Principal Investigator
    Direct real-time single molecule DNA sequencing
    NIH/NHGRI R21HG005096Sep 1, 2010 - Jun 30, 2013
    Role: Principal Investigator
    Genome Sequencing by Natural DNA Synthesis on Amplified DNA Clones
    NIH/NHGRI R01HG004804Aug 19, 2008 - May 31, 2012
    Role: Principal Investigator
    Genome Sequencing by Ligation Using Nano-Arrays of Single DNA Molecules
    NIH/NHGRI R21HG004130Sep 29, 2006 - Sep 30, 2009
    Role: Principal Investigator
    Massively Parallel Cloning and Sequencing of DNA
    NIH/NHGRI R21HG003587Aug 1, 2005 - May 31, 2008
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. DNA multi-bit non-volatile memory and bit-shifting operations using addressable electrode arrays and electric field-induced hybridization. Nat Commun. 2018 01 18; 9(1):281. Song Y, Kim S, Heller MJ, Huang X. PMID: 29348493.
      View in: PubMed   Mentions:    Fields:    
    2. Measurement of incorporation kinetics of non-fluorescent native nucleotides by DNA polymerases using fluorescence microscopy. Nucleic Acids Res. 2017 Dec 01; 45(21):e175. Walsh MT, Huang X. PMID: 29036327.
      View in: PubMed   Mentions:    Fields:    
    3. Ultraaccurate genome sequencing and haplotyping of single human cells. Proc Natl Acad Sci U S A. 2017 11 21; 114(47):12512-12517. Chu WK, Edge P, Lee HS, Bansal V, Bafna V, Huang X, Zhang K. PMID: 29078313.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    4. Capture and enumeration of mRNA transcripts from single cells using a microfluidic device. Lab Chip. 2015 Jul 21; 15(14):2968-80. Walsh MT, Hsiao AP, Lee HS, Liu Z, Huang X. PMID: 26040942.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    5. Measurement of DNA Polymerase Incorporation Kinetics of Dye-Labeled Nucleotides Using Total Internal Reflection Fluorescence Microscopy. Biochemistry. 2015 Jul 07; 54(26):4019-21. Walsh MT, Roller EE, Ko KS, Huang X. PMID: 26096371.
      View in: PubMed   Mentions: 4     Fields:    
    6. Microfluidic devices with permeable polymer barriers for capture and transport of biomolecules and cells. Lab Chip. 2013 Sep 07; 13(17):3389-97. Lee HS, Chu WK, Zhang K, Huang X. PMID: 23828542.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    7. Linear nicking endonuclease-mediated strand-displacement DNA amplification. Anal Biochem. 2011 Jul 01; 414(1):58-69. Joneja A, Huang X. PMID: 21342654.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    8. Fabrication of DNA polymer brush arrays by destructive micropatterning and rolling-circle amplification. Macromol Biosci. 2011 May 12; 11(5):607-17. Barbee KD, Chandrangsu M, Huang X. PMID: 21305694.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    9. Multiplexed protein detection using antibody-conjugated microbead arrays in a microfabricated electrophoretic device. Lab Chip. 2010 Nov 21; 10(22):3084-93. Barbee KD, Hsiao AP, Roller EE, Huang X. PMID: 20820631.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    10. Microfluidic Device for Capture and Isolation of Single Cells. Proc SPIE Int Soc Opt Eng. 2010 Aug 01; 7759. Hsiao AP, Barbee KD, Huang X. PMID: 21614137.
      View in: PubMed   Mentions:
    11. DNA sequencing by denaturation: experimental proof of concept with an integrated fluidic device. Lab Chip. 2010 May 07; 10(9):1153-9. Chen YJ, Roller EE, Huang X. PMID: 20390134.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    12. Electric field directed assembly of high-density microbead arrays. Lab Chip. 2009 Nov 21; 9(22):3268-74. Barbee KD, Hsiao AP, Heller MJ, Huang X. PMID: 19865735.
      View in: PubMed   Mentions: 10     Fields:    
    13. A device for automated hydrodynamic shearing of genomic DNA. Biotechniques. 2009 Jun; 46(7):553-6. Joneja A, Huang X. PMID: 19594456.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. DNA sequencing by denaturation: principle and thermodynamic simulations. Anal Biochem. 2009 Jan 01; 384(1):170-9. Chen YJ, Huang X. PMID: 18930015.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    15. Magnetic assembly of high-density DNA arrays for genomic analyses. Anal Chem. 2008 Mar 15; 80(6):2149-54. Barbee KD, Huang X. PMID: 18260655.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
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