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William Cain

TitleEmeritus Professor
InstitutionUniversity of California San Diego
DepartmentSurgery
Address9500 Gilman Drive #0957
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Human Sensory Irritation From Volitile Organic Compounds
    NIH/NIDCD R01DC005602Aug 4, 2003 - Jul 31, 2008
    Role: Principal Investigator
    CLINICAL OLFACTORY PSYCHOPHYSICS
    NIH/NIDCD R01DC000284Dec 1, 1984 - Mar 31, 2001
    Role: Principal Investigator
    CLINICAL OLFACTORY PSYCHOPHYSICS
    NIH/NINDS R01NS021644Dec 1, 1984 - Nov 30, 1991
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Abraham MH, Sánchez-Moreno R, Cometto-Muñiz JE, Cain W. An algorithm for 353 odor detection thresholds in humans. Chem Senses. 2012 Mar; 37(3):207-18. PMID: 21976369; PMCID: PMC3278675.
    2. Cain W, Dourson ML, Kohrman-Vincent MJ, Allen BC. Human chemosensory perception of methyl isothiocyanate: chemesthesis and odor. Regul Toxicol Pharmacol. 2010 Nov; 58(2):173-80. PMID: 20633589.
      View in: PubMed
    3. Schmidt R, Cain W. Making scents: dynamic olfactometry for threshold measurement. Chem Senses. 2010 Feb; 35(2):109-20. PMID: 19965900; PMCID: PMC2805809.
    4. Abraham MH, Sánchez-Moreno R, Gil-Lostes J, Acree WE, Cometto-Muñiz JE, Cain W. The biological and toxicological activity of gases and vapors. Toxicol In Vitro. 2010 Mar; 24(2):357-62. PMID: 19913608; PMCID: PMC2935277.
    5. Cometto-Muñiz JE, Cain W, Abraham MH, Gil-Lostes J. Concentration-detection functions for the odor of homologous n-acetate esters. Physiol Behav. 2008 Dec 15; 95(5):658-67. PMID: 18950650; PMCID: PMC2639399.
    6. Abraham MH, Gil-Lostes J, Acree WE, Cometto-Muñiz JE, Cain W. Solvation parameters for mercury and mercury(II) compounds: calculation of properties of environmental interest. J Environ Monit. 2008 Apr; 10(4):435-42. PMID: 18385864.
      View in: PubMed
    7. Cain W, Schmidt R, Wolkoff P. Olfactory detection of ozone and D-limonene: reactants in indoor spaces. Indoor Air. 2007 Oct; 17(5):337-47. PMID: 17880630.
      View in: PubMed
    8. Cain W, Jalowayski AA, Schmidt R, Kleinman M, Magruder K, Lee KC, Culver BD. Chemesthetic responses to airborne mineral dusts: boric acid compared to alkaline materials. Int Arch Occup Environ Health. 2008 Jan; 81(3):337-45. PMID: 17609973.
      View in: PubMed
    9. Abraham MH, Sánchez-Moreno R, Cometto-Muñiz JE, Cain W. A quantitative structure activity analysis on the relative sensitivity of the olfactory and the nasal trigeminal chemosensory systems. Chem Senses. 2007 Sep; 32(7):711-9. PMID: 17573355.
      View in: PubMed
    10. Cometto-Muñiz JE, Cain W, Abraham MH, Sánchez-Moreno R. Concentration-detection functions for eye irritation evoked by homologous n-alcohols and acetates approaching a cut-off point. Exp Brain Res. 2007 Sep; 182(1):71-9. PMID: 17503026.
      View in: PubMed
    11. Cain W, Schmidt R, Jalowayski AA. Odor and chemesthesis from exposures to glutaraldehyde vapor. Int Arch Occup Environ Health. 2007 Aug; 80(8):721-31. PMID: 17429675.
      View in: PubMed
    12. Cain W, Lee NS, Wise PM, Schmidt R, Ahn BH, Cometto-Muñiz JE, Abraham MH. Chemesthesis from volatile organic compounds: Psychophysical and neural responses. Physiol Behav. 2006 Jul 30; 88(4-5):317-24. PMID: 16806320.
      View in: PubMed
    13. Cometto-Muñiz JE, Cain W, Abraham MH, Sánchez-Moreno R. Chemical boundaries for detection of eye irritation in humans from homologous vapors. Toxicol Sci. 2006 Jun; 91(2):600-9. PMID: 16543295.
      View in: PubMed
    14. Cain W, de Wijk RA, Jalowayski AA, Pilla Caminha G, Schmidt R. Odor and chemesthesis from brief exposures to TXIB. Indoor Air. 2005 Dec; 15(6):445-57. PMID: 16268834.
      View in: PubMed
    15. Cometto-Muñiz JE, Cain W, Abraham MH. Molecular restrictions for human eye irritation by chemical vapors. Toxicol Appl Pharmacol. 2005 Sep 15; 207(3):232-43. PMID: 16129116.
      View in: PubMed
    16. Cometto-Muñiz JE, Cain W, Abraham MH. Determinants for nasal trigeminal detection of volatile organic compounds. Chem Senses. 2005 Oct; 30(8):627-42. PMID: 16141291.
      View in: PubMed
    17. Cometto-Muñiz JE, Cain W, Abraham MH. Odor detection of single chemicals and binary mixtures. Behav Brain Res. 2005 Jan 06; 156(1):115-23. PMID: 15474656.
      View in: PubMed
    18. Cometto-Muñiz JE, Cain W, Abraham MH. Chemosensory additivity in trigeminal chemoreception as reflected by detection of mixtures. Exp Brain Res. 2004 Sep; 158(2):196-206. PMID: 15112117; PMCID: PMC1388341.
    19. Cain W, Jalowayski AA, Kleinman M, Lee NS, Lee BR, Ahn BH, Magruder K, Schmidt R, Hillen BK, Warren CB, Culver BD. Sensory and associated reactions to mineral dusts: sodium borate, calcium oxide, and calcium sulfate. J Occup Environ Hyg. 2004 Apr; 1(4):222-36. PMID: 15204861.
      View in: PubMed
    20. Cometto-Muñiz JE, Cain W, Abraham MH. Detection of single and mixed VOCs by smell and by sensory irritation. Indoor Air. 2004; 14 Suppl 8:108-17. PMID: 15663466.
      View in: PubMed
    21. Abraham MH, Hassanisadi M, Jalali-Heravi M, Ghafourian T, Cain W, Cometto-Muniz JE. Draize rabbit eye test compatibility with eye irritation thresholds in humans: a quantitative structure-activity relationship analysis. Toxicol Sci. 2003 Dec; 76(2):384-91. PMID: 14514959.
      View in: PubMed
    22. Cometto-Muñiz JE, Cain W, Abraham MH. Quantification of chemical vapors in chemosensory research. Chem Senses. 2003 Jul; 28(6):467-77. PMID: 12907584.
      View in: PubMed
    23. Cometto-Muñiz JE, Cain W, Abraham MH. Dose-addition of individual odorants in the odor detection of binary mixtures. Behav Brain Res. 2003 Jan 06; 138(1):95-105. PMID: 12493633.
      View in: PubMed
    24. Olsson MJ, Cain W. Implicit and explicit memory for odors: hemispheric differences. Mem Cognit. 2003 Jan; 31(1):44-50. PMID: 12699142.
      View in: PubMed
    25. Mendell MJ, Fisk WJ, Kreiss K, Levin H, Alexander D, Cain W, Girman JR, Hines CJ, Jensen PA, Milton DK, Rexroat LP, Wallingford KM. Improving the health of workers in indoor environments: priority research needs for a national occupational research agenda. Am J Public Health. 2002 Sep; 92(9):1430-40. PMID: 12197969; PMCID: PMC1447254.
    26. Cain W, Schmidt R. Sensory detection of glutaraldehyde in drinking water-emergence of sensitivity and specific anosmia. Chem Senses. 2002 Jun; 27(5):425-33. PMID: 12052779.
      View in: PubMed
    27. Abraham MH, Gola JM, Cometto-Muniz JE, Cain W. A model for odour thresholds. Chem Senses. 2002 Feb; 27(2):95-104. PMID: 11839607.
      View in: PubMed
    28. Cometto-Muñiz JE, Cain W, Abraham MH, Gola JM. Psychometric functions for the olfactory and trigeminal detectability of butyl acetate and toluene. J Appl Toxicol. 2002 Jan-Feb; 22(1):25-30. PMID: 11807926.
      View in: PubMed
    29. Cain W, de Wijk R, Lulejian C, Schiet F, See LC. Odor identification: perceptual and semantic dimensions. Chem Senses. 1998 Jun; 23(3):309-26. PMID: 9669044.
      View in: PubMed
    30. Cain W, Algom D. Perceptual and mental mixtures in odor and in taste: are there similarities and differences between experiments or between modalities? Reply to Schifferstein (1997) J Exp Psychol Hum Percept Perform. 1997 Oct; 23(5):1588-93. PMID: 9336966.
      View in: PubMed
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