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Wenxian Fu

Title(s)Assistant Professor, Pediatrics
SchoolHealth Sciences
Phone858-246-0022
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Yang BH, Wang K, Wan S, Liang Y, Yuan X, Dong Y, Cho S, Xu W, Jepsen K, Feng GS, Lu LF, Xue HH, Fu W. TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases. Cell Rep. 2019 Jun 18; 27(12):3629-3645.e6. PMID: 31216480.
      View in: PubMed
    2. Li M, Zhao W, Wang Y, Jin L, Jin G, Sun X, Wang W, Wang K, Xu X, Hao J, Jin R, Fu W, Sun Y, Chang Y, Huang X, Zhou X, Wu H, Zhang K, Ge Q. A wave of Foxp3+ regulatory T cell accumulation in the neonatal liver plays unique roles in maintaining self-tolerance. Cell Mol Immunol. 2019 Jun 06. PMID: 31171863.
      View in: PubMed
    3. Ying W, Lee YS, Dong Y, Seidman JS, Yang M, Isaac R, Seo JB, Yang BH, Wollam J, Riopel M, McNelis J, Glass CK, Olefsky JM, Fu W. Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting ß Cell Proliferation and Function in Obesity. Cell Metab. 2019 Feb 05; 29(2):457-474.e5. PMID: 30595478.
      View in: PubMed
    4. Kraakman MJ, Liu Q, Postigo-Fernandez J, Ji R, Kon N, Larrea D, Namwanje M, Fan L, Chan M, Area-Gomez E, Fu W, Creusot RJ, Qiang L. PPAR? deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects. J Clin Invest. 2018 Jun 01; 128(6):2600-2612. PMID: 29589839.
      View in: PubMed
    5. Yuan X, Dong Y, Tsurushita N, Tso JY, Fu W. CD122 blockade restores immunological tolerance in autoimmune type 1 diabetes via multiple mechanisms. JCI Insight. 2018 Jan 25; 3(2). PMID: 29367461.
      View in: PubMed
    6. Chen K, Jih A, Osborn O, Kavaler ST, Fu W, Sasik R, Saito R, Kim JJ. Distinct gene signatures predict insulin resistance in young mice with high fat diet-induced obesity. Physiol Genomics. 2018 03 01; 50(3):144-157. PMID: 29341863.
      View in: PubMed
    7. Yuan X, Yang BH, Dong Y, Yamamura A, Fu W. CRIg, a tissue-resident macrophage specific immune checkpoint molecule, promotes immunological tolerance in NOD mice, via a dual role in effector and regulatory T cells. Elife. 2017 11 24; 6. PMID: 29171836.
      View in: PubMed
    8. Lee J, Liao R, Wang G, Yang BH, Luo X, Varki NM, Qiu SJ, Ren B, Fu W, Feng GS. Preventive Inhibition of Liver Tumorigenesis by Systemic Activation of Innate Immune Functions. Cell Rep. 2017 Nov 14; 21(7):1870-1882. PMID: 29141219.
      View in: PubMed
    9. Ying W, Riopel M, Bandyopadhyay G, Dong Y, Birmingham A, Seo JB, Ofrecio JM, Wollam J, Hernandez-Carretero A, Fu W, Li P, Olefsky JM. Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity. Cell. 2017 Oct 05; 171(2):372-384.e12. PMID: 28942920.
      View in: PubMed
    10. Cho S, Wu CJ, Nguyen DT, Lin LL, Chen MC, Khan AA, Yang BH, Fu W, Lu LF. A Novel miR-24-TCF1 Axis in Modulating Effector T Cell Responses. J Immunol. 2017 05 15; 198(10):3919-3926. PMID: 28404635.
      View in: PubMed
    11. Fu W, Farache J, Clardy SM, Hattori K, Mander P, Lee K, Rioja I, Weissleder R, Prinjha RK, Benoist C, Mathis D. Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and ß cells. Elife. 2014 Nov 19; 3:e04631. PMID: 25407682; PMCID: PMC4270084.
    12. Gutierrez DA, Fu W, Schonefeldt S, Feyerabend TB, Ortiz-Lopez A, Lampi Y, Liston A, Mathis D, Rodewald HR. Type 1 diabetes in NOD mice unaffected by mast cell deficiency. Diabetes. 2014 Nov; 63(11):3827-34. PMID: 24917576.
      View in: PubMed
    13. Engin F, Yermalovich A, Nguyen T, Ngyuen T, Hummasti S, Fu W, Eizirik DL, Mathis D, Hotamisligil GS. Restoration of the unfolded protein response in pancreatic ß cells protects mice against type 1 diabetes. Sci Transl Med. 2013 Nov 13; 5(211):211ra156. PMID: 24225943; PMCID: PMC4169117.
    14. Fu W, Ergun A, Lu T, Hill JA, Haxhinasto S, Fassett MS, Gazit R, Adoro S, Glimcher L, Chan S, Kastner P, Rossi D, Collins JJ, Mathis D, Benoist C. A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells. Nat Immunol. 2012 Oct; 13(10):972-80. PMID: 22961053; PMCID: PMC3698954.
    15. Fu W, Wojtkiewicz G, Weissleder R, Benoist C, Mathis D. Early window of diabetes determinism in NOD mice, dependent on the complement receptor CRIg, identified by noninvasive imaging. Nat Immunol. 2012 Feb 26; 13(4):361-8. PMID: 22366893; PMCID: PMC3309063.
    16. Fu W, Zhang Y, Zhang J, Chen WF. Cloning and characterization of mouse homolog of the CXC chemokine receptor CXCR1. Cytokine. 2005 Jul 07; 31(1):9-17. PMID: 15967374.
      View in: PubMed
    17. Fu W, Chen W. Roles of chemokines in thymopoiesis: redundancy and regulation. Cell Mol Immunol. 2004 Aug; 1(4):266-73. PMID: 16225769.
      View in: PubMed