Wendy Huang
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Title(s) | Assistant Professor, Cellular and Molecular Medicine |
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School | Vc-health Sciences-schools |
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Address | 9500 Gilman Drive # La Jolla CA 92093
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vCard | Download vCard |
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Biography New York University School of Medicine | Postdoctoral Fellowship | 2016 | Skirball Institute | University of California San Diego | Ph.D. | 2010 | Biomedical Sciences | University of California Berkeley | B.A. | 2005 | Molecular and Cellular Biology |
Overview To examine molecular mechanisms underlying immune-cell development and effector functions and to assess their contributions to immune homeostasis and pathologies.
Focus Area #1: To assess the contributions of RNA binding proteins, including RNA-helicases and RNA editing enzymes, to host immune homeostasis and autoimmune pathologies.
Focus Area #2: To assess the identify and characterize contributions of chromatin associated non-coding RNAs to host immune homeostasis and autoimmune pathologies.
Focus Area #3: To uncover the tissue-specific post-transcriptional and post-translational mechanisms that orchestrate local immune responses in models of mucosal inflammation, tumorigenesis, and autoimmunity.
Research ORNG Applications Bibliographic
Altmetrics Details
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
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RNA adenosine deaminase ADAR2 modulates T helper 17 cell effector function. bioRxiv. 2020.
Shengyun Ma, Benjamin S. Cho, Yuxin Li, Nazia Abbasi, Brian A. Yee, Ge Sun, Claire Luo, John T. Chang, Bing Zhou, Xiang-dong Fu, Gene W. Yeo, Wendy Jia Men Huang. . View Publication.
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The DNA Glycosylase NEIL2 Suppresses Fusobacterium-Infection-Induced Inflammation and DNA Damage in Colonic Epithelial Cells. Cells. 2020 08 28; 9(9).
Sayed IM, Chakraborty A, Abd El-Hafeez AA, Sharma A, Sahan AZ, Huang WJM, Sahoo D, Ghosh P, Hazra TK, Das S. PMID: 32872214.
View in: PubMed Mentions: Fields:
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DDX5 promotes oncogene C3 and FABP1 expressions and drives intestinal inflammation and tumorigenesis. Life Sci Alliance. 2020 10; 3(10).
Abbasi N, Long T, Li Y, Yee BA, Cho BS, Hernandez JE, Ma E, Patel PR, Sahoo D, Sayed IM, Varki N, Das S, Ghosh P, Yeo GW, Huang WJM. PMID: 32817263.
View in: PubMed Mentions: Fields:
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Early precursors and molecular determinants of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing. Sci Immunol. 2020 05 15; 5(47).
Kurd NS, He Z, Louis TL, Milner JJ, Omilusik KD, Jin W, Tsai MS, Widjaja CE, Kanbar JN, Olvera JG, Tysl T, Quezada LK, Boland BS, Huang WJ, Murre C, Goldrath AW, Yeo GW, Chang JT. PMID: 32414833.
View in: PubMed Mentions: 4 Fields: Translation: HumansAnimalsCells
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Noncoding RNAs in inflammation and colorectal cancer. RNA Biol. 2020 Nov; 17(11):1628-1635.
Ma S, Long T, Huang WJM. PMID: 31847691.
View in: PubMed Mentions: 1 Fields:
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Bacteria engineered to produce IL-22 in intestine induce expression of REG3G to reduce ethanol-induced liver disease in mice. Gut. 2019 08; 68(8):1504-1515.
Hendrikx T, Duan Y, Wang Y, Oh JH, Alexander LM, Huang W, Stärkel P, Ho SB, Gao B, Fiehn O, Emond P, Sokol H, van Pijkeren JP, Schnabl B. PMID: 30448775.
View in: PubMed Mentions: 23 Fields: Translation: AnimalsCells
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Regulation of RORγt in Inflammatory Lymphoid Cell Differentiation. Cold Spring Harb Symp Quant Biol. 2015; 80:257-63.
Huang W, Littman DR. PMID: 26968628.
View in: PubMed Mentions: 2 Fields: Translation: HumansAnimalsCells
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An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses. Cell. 2015 Oct 08; 163(2):381-93.
Sano T, Huang W, Hall JA, Yang Y, Chen A, Gavzy SJ, Lee JY, Ziel JW, Miraldi ER, Domingos AI, Bonneau R, Littman DR. PMID: 26411290.
View in: PubMed Mentions: 135 Fields: Translation: AnimalsCells
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The transcriptional specificity of NF-κB dimers is coded within the κB DNA response elements. Cell Rep. 2012 Oct 25; 2(4):824-39.
Wang VY, Huang W, Asagiri M, Spann N, Hoffmann A, Glass C, Ghosh G. PMID: 23063365.
View in: PubMed Mentions: 41 Fields: Translation: AnimalsCells
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A validated regulatory network for Th17 cell specification. Cell. 2012 Oct 12; 151(2):289-303.
Ciofani M, Madar A, Galan C, Sellars M, Mace K, Pauli F, Agarwal A, Huang W, Parkhurst CN, Muratet M, Newberry KM, Meadows S, Greenfield A, Yang Y, Jain P, Kirigin FK, Birchmeier C, Wagner EF, Murphy KM, Myers RM, Bonneau R, Littman DR. PMID: 23021777.
View in: PubMed Mentions: 382 Fields: Translation: HumansAnimalsCells
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A global clustering algorithm to identify long intergenic non-coding RNA--with applications in mouse macrophages. PLoS One. 2011; 6(9):e24051.
Garmire LX, Garmire DG, Huang W, Yao J, Glass CK, Subramaniam S. PMID: 21980340.
View in: PubMed Mentions: 19 Fields: Translation: HumansAnimalsCells
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Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Nature. 2011 Feb 17; 470(7334):414-8.
Huang W, Ghisletti S, Saijo K, Gandhi M, Aouadi M, Tesz GJ, Zhang DX, Yao J, Czech MP, Goode BL, Rosenfeld MG, Glass CK. PMID: 21331046.
View in: PubMed Mentions: 75 Fields: Translation: HumansAnimalsCells
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Serum response factor utilizes distinct promoter- and enhancer-based mechanisms to regulate cytoskeletal gene expression in macrophages. Mol Cell Biol. 2011 Feb; 31(4):861-75.
Sullivan AL, Benner C, Heinz S, Huang W, Xie L, Miano JM, Glass CK. PMID: 21135125.
View in: PubMed Mentions: 33 Fields: Translation: AnimalsCells
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Nuclear receptors and inflammation control: molecular mechanisms and pathophysiological relevance. Arterioscler Thromb Vasc Biol. 2010 Aug; 30(8):1542-9.
Huang W, Glass CK. PMID: 20631355.
View in: PubMed Mentions: 44 Fields: Translation: HumansAnimalsCells
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Low doses of lipopolysaccharide and minimally oxidized low-density lipoprotein cooperatively activate macrophages via nuclear factor kappa B and activator protein-1: possible mechanism for acceleration of atherosclerosis by subclinical endotoxemia. Circ Res. 2010 Jul 09; 107(1):56-65.
Wiesner P, Choi SH, Almazan F, Benner C, Huang W, Diehl CJ, Gonen A, Butler S, Witztum JL, Glass CK, Miller YI. PMID: 20489162.
View in: PubMed Mentions: 77 Fields: Translation: AnimalsCells
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Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint. Mol Cell. 2009 Jul 10; 35(1):48-57.
Huang W, Ghisletti S, Perissi V, Rosenfeld MG, Glass CK. PMID: 19595715.
View in: PubMed Mentions: 55 Fields: Translation: AnimalsCells
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Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways. Genes Dev. 2009 Mar 15; 23(6):681-93.
Ghisletti S, Huang W, Jepsen K, Benner C, Hardiman G, Rosenfeld MG, Glass CK. PMID: 19299558.
View in: PubMed Mentions: 119 Fields: Translation: AnimalsCells
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Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma. Mol Cell. 2007 Jan 12; 25(1):57-70.
Ghisletti S, Huang W, Ogawa S, Pascual G, Lin ME, Willson TM, Rosenfeld MG, Glass CK. PMID: 17218271.
View in: PubMed Mentions: 208 Fields: Translation: HumansAnimalsCells
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Year | Publications |
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2007 | 1 | 2009 | 2 | 2010 | 3 | 2011 | 2 | 2012 | 2 | 2015 | 1 | 2016 | 1 | 2018 | 1 | 2019 | 1 | 2020 | 4 |
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This graph shows the number and percent of publications by field.
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