Tsung-ting Kuo

Title(s)Assistant Adjunct Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0002-8728-4477 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California San Diego (UCSD), USAPostdoc01/2019Biomedical Informatics
    National Taiwan University (NTU), TaiwanPh.D.01/2014Networking and Multimedia
    National Chao Tung University (NCTU), TaiwanM.S.06/2003Computer and Information Science
    National Cheng Kung University (NCKU), TaiwanB.S.06/2001Computer Science and Information Engineering
    Collapse Awards and Honors
    UCSD2023Academic Senate Health Science Travel Award
    UCSD2021Academic Senate Health Science Travel Award
    UCSD Health Department of Biomedical Informatics (DBMI)2020Faculty of the Year
    UCSD2019Academic Senate Health Science Travel Award
    UCSD2018Chancellor's Outstanding Postdoctoral Scholar Award
    Office of the National Coordinator for Health Information Technology (ONC)2016Use of Blockchain in Health IT and Health-related Research Challenge Winner
    Association for Computational Linguistics and Chinese Language Processing (ACLCLP)2014Best Doctoral Dissertation Award, Runner-Up
    Taiwan Institute of Electrical and Electronic Engineering (TIEEE)2014Best Doctoral Dissertation Award, Runner-Up
    Conference on Technologies and Applications of Artificial Intelligence (TAAI)2014Merit Paper Award
    ACM Special Interest Group on Knowledge Discovery and Data Mining (SIGKDD)2013Student Travel Award
    Foundation for the Advancement of Outstanding Scholarship (FAOS)2013Outstanding Students Conference Travel Grant
    Association for Computational Linguistics and Chinese Language Processing (ACLCLP)2012Outstanding Students Conference Travel Grant
    ACM SIGKDD2011KDD Cup 2011 Champion of Track 1 and 2
    NTU2011Outstanding Performance Scholarship
    ACM Special Interest Group on Computer GRAPHics and Interactive Techniques (SIGGRAPH)2010Student Research Competition Semi-Finalist
    ACM SIGKDD2010KDD Cup 2010 Champion of All-Team and Student-Team
    ACM SIGKDD2009KDD Cup 2009 3rd Place of Slow Track
    CyberLink2009Outstanding Scholarship
    ACM SIGKDD2008KDD Cup 2008 Co-Champion (with IBM Research)
    NTU2008Outstanding Study Group Award
    NCTU2002Presidential Award
    Institute of Information & Computing Machinery (IICM)2001Technology Graduate Record Examinations Computer Science Contest 46th Place (Top 4.3% in Taiwan)
    NCKU Computer Science and Information Engineering2001Graduation Project Contest Outstanding Award
    NCKU Computer Science and Information Engineering2001Programming Contest 2nd Place

    Collapse Overview 
    Collapse Overview
    Dr. Tsung-Ting Kuo is an Assistant Professor of Medicine in University of California San Diego (UCSD) Health Department of Biomedical Informatics (DBMI). He earned his PhD from National Taiwan University (NTU) in the Institute of Networking and Multimedia. Prior to becoming a faculty member, he was a Postdoctoral Scholar at UCSD DBMI and received the UCSD Chancellor’s Outstanding Postdoctoral Scholar Award. He was a major contributor towards the UCSD DBMI team winning the Office of the National Coordinator for Health Information Technology (ONC) healthcare blockchain challenge, and also the NTU team winning the Association for Computing Machinery (ACM) Knowledge Discovery and Data Mining (KDD) Cup competition four times. He was awarded a NIH R01 Research Project Grant, a K99/R00 Pathway to Independence Award with an Administrative Supplement, a R13 Support for Conferences and Scientific Meetings Grant, as well as UCSD Academic Senate Health Science Research Grants, for blockchain-based and predictive biomedical, healthcare and genomic studies. His research focuses on blockchain technologies, machine learning, and natural language processing.

    Collapse Research 
    Collapse Research Activities and Funding
    Positive Clostridioides Difficile Test Results Prediction
    UCSD Academic Senate RG114001Jun 1, 2023 - May 31, 2024
    Role: Principal Investigator
    iDASH Genome Privacy and Security Competition Workshop
    NIH R13HG012902Feb 16, 2023 - Jan 31, 2028
    Role: Contact Multiple Principal Investigator
    SOCAL: Privacy-protecting Sharing Of Clinical Data Across Laboratories
    NIH R01EB031030Sep 30, 2022 - Jun 30, 2026
    Role: Principal Investigator
    A FAIR Bridge2AI Center (FABRIC)
    NIH U54HG012510Jul 8, 2022 - Apr 30, 2026
    Role: Co-Investigator
    Genetic & Social Determinants of Health: Center for Admixture Science and Technology
    NIH RM1HG011558Sep 22, 2021 - Jun 30, 2026
    Role: Co-Investigator
    COVID-19 Image Sharing with Improved Availability, Provenance, and Immutability
    UCSD Academic Senate RG100836Mar 1, 2021 - Feb 28, 2022
    Role: Principal Investigator
    RADx-Rad Discoveries & Data: Consortium Coordination Center Program Organization
    NIH U24LM013755Dec 21, 2020 - Nov 30, 2024
    Role: Co-Investigator
    iAGREE: A Multi-Center, Networked Patient Consent Study
    NIH R01HG011066May 1, 2020 - Feb 28, 2025
    Role: Co-Investigator
    All-of-Us Phase II Consortium Demo Project (Parent: California Precision Medicine Research Program Consortium)
    NIH OT2OD026552 D040Nov 1, 2019 - Mar 31, 2020
    Role: Co-Investigator
    Blockchain-based Predictive Modeling on Real-World Networks
    UCSD Academic Senate RG084150Jun 1, 2019 - May 31, 2020
    Role: Principal Investigator
    BECKON - Block Estimate Chain: creating Knowledge ON demand & protecting privacy
    NIH R00HG009680May 1, 2019 - Apr 30, 2022
    Role: Principal Investigator
    CALIFORNIA: Cloud-agnostic Architecture to Locate Indexed FAIR Objects and safely Reuse them in New Integrated Analyses
    NIH OT3OD025462Sep 30, 2017 - Nov 30, 2018
    Role: Co-Investigator
    BECKON - Block Estimate Chain: creating Knowledge ON demand & protecting privacy
    NIH K99HG009680Aug 24, 2017 - Jun 30, 2019
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Biomedical blockchain with practical implementations and quantitative evaluations: a systematic review. J Am Med Inform Assoc. 2024 May 20; 31(6):1423-1435. Lacson R, Yu Y, Kuo TT, Ohno-Machado L. PMID: 38726710; PMCID: PMC11105130.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Early prediction of long hospital stay for Intensive Care units readmission patients using medication information. Comput Biol Med. 2024 Apr 08; 174:108451. Zhang M, Kuo TT. PMID: 38603899.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Profiling Clinical Researchers Effectively using Embeddings and Clustering. medRxiv. 2024 Jan 17. Sharma A, Edelson M, Kuo TT. PMID: 38293223; PMCID: PMC10827253.
      View in: PubMed   Mentions:
    4. Blockchain-enabled immutable, distributed, and highly available clinical research activity logging system for federated COVID-19 data analysis from multiple institutions. J Am Med Inform Assoc. 2023 05 19; 30(6):1167-1178. Kuo TT, Pham A, Edelson ME, Kim J, Chan J, Gupta Y, Ohno-Machado L, R2D2 Consortium. PMID: 36916740; PMCID: PMC10198529.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    5. A hierarchical strategy to minimize privacy risk when linking "De-identified" data in biomedical research consortia. J Biomed Inform. 2023 03; 139:104322. Ohno-Machado L, Jiang X, Kuo TT, Tao S, Chen L, Ram PM, Zhang GQ, Xu H. PMID: 36806328; PMCID: PMC10975485.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. The evolving privacy and security concerns for genomic data analysis and sharing as observed from the iDASH competition. J Am Med Inform Assoc. 2022 11 14; 29(12):2182-2190. Kuo TT, Jiang X, Tang H, Wang X, Harmanci A, Kim M, Post K, Bu D, Bath T, Kim J, Liu W, Chen H, Ohno-Machado L. PMID: 36164820; PMCID: PMC9667175.
      View in: PubMed   Mentions: 3     Fields:    
    7. Quorum-based model learning on a blockchain hierarchical clinical research network using smart contracts. Int J Med Inform. 2023 01; 169:104924. Kuo TT, Pham A. PMID: 36402113; PMCID: PMC9984225.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Predicting COVID-19 county-level case number trend by combining demographic characteristics and social distancing policies. JAMIA Open. 2022 Oct; 5(3):ooac056. Li MM, Pham A, Kuo TT. PMID: 35855422; PMCID: PMC9278037.
      View in: PubMed   Mentions:
    9. Generalizable prediction of COVID-19 mortality on worldwide patient data. JAMIA Open. 2022 Jul; 5(2):ooac036. Edelson M, Kuo TT. PMID: 35663116; PMCID: PMC9129227.
      View in: PubMed   Mentions: 2  
    10. NLM's sponsorship of research in biomedical informatics (1985-2016). Inf Serv Use. 2022; 42(1):61-70. Kuo TT, Ohno-Machado L. PMID: 35600120; PMCID: PMC9108565.
      View in: PubMed   Mentions:
    11. CertificateChain: decentralized healthcare training certificate management system using blockchain and smart contracts. JAMIA Open. 2022 Apr; 5(1):ooac019. Tellew J, Kuo TT. PMID: 35571362; PMCID: PMC9097703.
      View in: PubMed   Mentions: 5  
    12. Detecting model misconducts in decentralized healthcare federated learning. Int J Med Inform. 2021 Dec 09; 158:104658. Kuo TT, Pham A. PMID: 34923447; PMCID: PMC10017272.
      View in: PubMed   Mentions: 3     Fields:    
    13. Previewable Contract-Based On-Chain X-Ray Image Sharing Framework for Clinical Research. Int J Med Inform. 2021 12; 156:104599. Li MM, Kuo TT. PMID: 34628257; PMCID: PMC8479449.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    14. Benchmarking blockchain-based gene-drug interaction data sharing methods: A case study from the iDASH 2019 secure genome analysis competition blockchain track. Int J Med Inform. 2021 10; 154:104559. Kuo TT, Bath T, Ma S, Pattengale N, Yang M, Cao Y, Hudson CM, Kim J, Post K, Xiong L, Ohno-Machado L. PMID: 34474309; PMCID: PMC9933142.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    15. Privacy-protecting, reliable response data discovery using COVID-19 patient observations. J Am Med Inform Assoc. 2021 07 30; 28(8):1765-1776. Kim J, Neumann L, Paul P, Day ME, Aratow M, Bell DS, Doctor JN, Hinske LC, Jiang X, Kim KK, Matheny ME, Meeker D, Pletcher MJ, Schilling LM, SooHoo S, Xu H, Zheng K, Ohno-Machado L, R2D2 Consortium. PMID: 34051088; PMCID: PMC8194878.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    16. Hypertension prevalence in the All of Us Research Program among groups traditionally underrepresented in medical research. Sci Rep. 2021 06 22; 11(1):12849. Chandler PD, Clark CR, Zhou G, Noel NL, Achilike C, Mendez L, Ramirez AH, Loperena-Cortes R, Mayo K, Cohn E, Ohno-Machado L, Boerwinkle E, Cicek M, Qian J, Schully S, Ratsimbazafy F, Mockrin S, Gebo K, Dedier JJ, Murphy SN, Smoller JW, Karlson EW, All of Us Research Program Investigators. PMID: 34158555; PMCID: PMC8219813.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    17. Predictive Analytics for Glaucoma Using Data From the All of Us Research Program. Am J Ophthalmol. 2021 07; 227:74-86. Baxter SL, Saseendrakumar BR, Paul P, Kim J, Bonomi L, Kuo TT, Loperena R, Ratsimbazafy F, Boerwinkle E, Cicek M, Clark CR, Cohn E, Gebo K, Mayo K, Mockrin S, Schully SD, Ramirez A, Ohno-Machado L, All of Us Research Program Investigators. PMID: 33497675; PMCID: PMC8184631.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    18. iDASH secure genome analysis competition 2018: blockchain genomic data access logging, homomorphic encryption on GWAS, and DNA segment searching. BMC Med Genomics. 2020 07 21; 13(Suppl 7):98. Kuo TT, Jiang X, Tang H, Wang X, Bath T, Bu D, Wang L, Harmanci A, Zhang S, Zhi D, Sofia HJ, Ohno-Machado L. PMID: 32693816; PMCID: PMC7372776.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    19. The anatomy of a distributed predictive modeling framework: online learning, blockchain network, and consensus algorithm. JAMIA Open. 2020 Jul; 3(2):201-208. Kuo TT. PMID: 32734160; PMCID: PMC7382618.
      View in: PubMed   Mentions: 8  
    20. EXpectation Propagation LOgistic REgRession on permissioned blockCHAIN (ExplorerChain): decentralized online healthcare/genomics predictive model learning. J Am Med Inform Assoc. 2020 05 01; 27(5):747-756. Kuo TT, Gabriel RA, Cidambi KR, Ohno-Machado L. PMID: 32364235; PMCID: PMC7309256.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    21. Comparison of Smart Contract Blockchains for Healthcare Applications. AMIA Annu Symp Proc. 2019; 2019:1266-1275. Yu H, Sun H, Wu D, Kuo TT. PMID: 32308924; PMCID: PMC7153130.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    22. Privacy-preserving model learning on a blockchain network-of-networks. J Am Med Inform Assoc. 2020 03 01; 27(3):343-354. Kuo TT, Kim J, Gabriel RA. PMID: 31943009; PMCID: PMC7025358.
      View in: PubMed   Mentions: 11     Fields:    
    23. Machine Learning-Based Predictive Modeling of Surgical Intervention in Glaucoma Using Systemic Data From Electronic Health Records. Am J Ophthalmol. 2019 12; 208:30-40. Baxter SL, Marks C, Kuo TT, Ohno-Machado L, Weinreb RN. PMID: 31323204; PMCID: PMC6888922.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    24. Fair compute loads enabled by blockchain: sharing models by alternating client and server roles. J Am Med Inform Assoc. 2019 05 01; 26(5):392-403. Kuo TT, Gabriel RA, Ohno-Machado L. PMID: 30892656; PMCID: PMC7787356.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    25. Comparison of blockchain platforms: a systematic review and healthcare examples. J Am Med Inform Assoc. 2019 05 01; 26(5):462-478. Kuo TT, Zavaleta Rojas H, Ohno-Machado L. PMID: 30907419; PMCID: PMC7787359.
      View in: PubMed   Mentions: 43     Fields:    
    26. 'Fit-for-purpose?' - challenges and opportunities for applications of blockchain technology in the future of healthcare. BMC Med. 2019 03 27; 17(1):68. Mackey TK, Kuo TT, Gummadi B, Clauson KA, Church G, Grishin D, Obbad K, Barkovich R, Palombini M. PMID: 30914045; PMCID: PMC6436239.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    27. Identifying and characterizing highly similar notes in big clinical note datasets. J Biomed Inform. 2018 06; 82:63-69. Gabriel RA, Kuo TT, McAuley J, Hsu CN. PMID: 29679685.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    28. Blockchain distributed ledger technologies for biomedical and health care applications. J Am Med Inform Assoc. 2017 Nov 01; 24(6):1211-1220. Kuo TT, Kim HE, Ohno-Machado L. PMID: 29016974; PMCID: PMC6080687.
      View in: PubMed   Mentions: 138     Fields:    
    29. Ensembles of NLP Tools for Data Element Extraction from Clinical Notes. AMIA Annu Symp Proc. 2016; 2016:1880-1889. Kuo TT, Rao P, Maehara C, Doan S, Chaparro JD, Day ME, Farcas C, Ohno-Machado L, Hsu CN. PMID: 28269947; PMCID: PMC5333200.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    30. Finding Related Publications: Extending the Set of Terms Used to Assess Article Similarity. AMIA Jt Summits Transl Sci Proc. 2016; 2016:225-34. Wei W, Marmor R, Singh S, Wang S, Demner-Fushman D, Kuo TT, Hsu CN, Ohno-Machado L. PMID: 27570676; PMCID: PMC5001748.
      View in: PubMed   Mentions: 4  
    31. Weakly supervised learning of biomedical information extraction from curated data. BMC Bioinformatics. 2016 Jan 11; 17 Suppl 1:1. Jain S, Tumkur KR, Kuo TT, Bhargava S, Lin G, Hsu CN. PMID: 26817711; PMCID: PMC4847485.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
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